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Items: 1 to 20 of 139


Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype.

Metz SW, Thomas A, Brackbill A, Xianwen Y, Stone M, Horvath K, Miley MJ, Luft C, DeSimone JM, Tian S, de Silva AM.

PLoS Negl Trop Dis. 2018 Sep 24;12(9):e0006793. doi: 10.1371/journal.pntd.0006793. eCollection 2018 Sep.


Formulation of High-Performance Dry Powder Aerosols for Pulmonary Protein Delivery.

Wilson EM, Luft JC, DeSimone JM.

Pharm Res. 2018 Aug 23;35(10):195. doi: 10.1007/s11095-018-2452-z.


Use of iontophoresis for the treatment of cancer.

Byrne JD, Yeh JJ, DeSimone JM.

J Control Release. 2018 Aug 28;284:144-151. doi: 10.1016/j.jconrel.2018.06.020. Epub 2018 Jun 15. Review.


Spatially controlled coating of continuous liquid interface production microneedles for transdermal protein delivery.

Caudill CL, Perry JL, Tian S, Luft JC, DeSimone JM.

J Control Release. 2018 Aug 28;284:122-132. doi: 10.1016/j.jconrel.2018.05.042. Epub 2018 Jun 9.


Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer.

Byrne JD, Jajja MRN, O'Neill AT, Schorzman AN, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ.

Cancer Chemother Pharmacol. 2018 Jun;81(6):991-998. doi: 10.1007/s00280-018-3570-3. Epub 2018 Mar 30.


Controlling release from 3D printed medical devices using CLIP and drug-loaded liquid resins.

Bloomquist CJ, Mecham MB, Paradzinsky MD, Janusziewicz R, Warner SB, Luft JC, Mecham SJ, Wang AZ, DeSimone JM.

J Control Release. 2018 May 28;278:9-23. doi: 10.1016/j.jconrel.2018.03.026. Epub 2018 Mar 27.


Extending antigen release from particulate vaccines results in enhanced antitumor immune response.

Kapadia CH, Tian S, Perry JL, Sailer D, Christopher Luft J, DeSimone JM.

J Control Release. 2018 Jan 10;269:393-404. doi: 10.1016/j.jconrel.2017.11.020. Epub 2017 Nov 13.


Mechanism of ion transport in perfluoropolyether electrolytes with a lithium salt.

Timachova K, Chintapalli M, Olson KR, Mecham SJ, DeSimone JM, Balsara NP.

Soft Matter. 2017 Aug 16;13(32):5389-5396. doi: 10.1039/c7sm00794a.


Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy.

Min Y, Roche KC, Tian S, Eblan MJ, McKinnon KP, Caster JM, Chai S, Herring LE, Zhang L, Zhang T, DeSimone JM, Tepper JE, Vincent BG, Serody JS, Wang AZ.

Nat Nanotechnol. 2017 Sep;12(9):877-882. doi: 10.1038/nnano.2017.113. Epub 2017 Jun 26.


Incipient microphase separation in short chain perfluoropolyether-block-poly(ethylene oxide) copolymers.

Chintapalli M, Timachova K, Olson KR, Banaszak M, Thelen JL, Mecham SJ, DeSimone JM, Balsara NP.

Soft Matter. 2017 Jun 7;13(22):4047-4056. doi: 10.1039/c7sm00738h.


Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location.

Perry JL, Reuter KG, Luft JC, Pecot CV, Zamboni W, DeSimone JM.

Nano Lett. 2017 May 10;17(5):2879-2886. doi: 10.1021/acs.nanolett.7b00021. Epub 2017 Apr 11.


Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.

Bowerman CJ, Byrne JD, Chu KS, Schorzman AN, Keeler AW, Sherwood CA, Perry JL, Luft JC, Darr DB, Deal AM, Napier ME, Zamboni WC, Sharpless NE, Perou CM, DeSimone JM.

Nano Lett. 2017 Jan 11;17(1):242-248. doi: 10.1021/acs.nanolett.6b03971. Epub 2016 Dec 22.


Novel materials.

Rogers JA, DeSimone JM.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11667-11669. No abstract available. Erratum in: Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7346.


Layerless fabrication with continuous liquid interface production.

Janusziewicz R, Tumbleston JR, Quintanilla AL, Mecham SJ, DeSimone JM.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11703-11708. Epub 2016 Sep 26.


Organic Polymer Chemistry in the Context of Novel Processes.

DeSimone JM, Mecham SJ, Farrell CL.

ACS Cent Sci. 2016 Sep 28;2(9):588-597. Epub 2016 Sep 13. Review.


Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production.

Johnson AR, Caudill CL, Tumbleston JR, Bloomquist CJ, Moga KA, Ermoshkin A, Shirvanyants D, Mecham SJ, Luft JC, DeSimone JM.

PLoS One. 2016 Sep 8;11(9):e0162518. doi: 10.1371/journal.pone.0162518. eCollection 2016.


Reduction Sensitive PEG Hydrogels for Codelivery of Antigen and Adjuvant To Induce Potent CTLs.

Kapadia CH, Tian S, Perry JL, Luft JC, DeSimone JM.

Mol Pharm. 2016 Oct 3;13(10):3381-3394. Epub 2016 Sep 22.


Co-opting Moore's law: Therapeutics, vaccines and interfacially active particles manufactured via PRINT®.

DeSimone JM.

J Control Release. 2016 Oct 28;240:541-543. doi: 10.1016/j.jconrel.2016.07.019. Epub 2016 Jul 14. Review.


Pulmonary Delivery of Butyrylcholinesterase as a Model Protein to the Lung.

Rahhal TB, Fromen CA, Wilson EM, Kai MP, Shen TW, Luft JC, DeSimone JM.

Mol Pharm. 2016 May 2;13(5):1626-35. doi: 10.1021/acs.molpharmaceut.6b00066. Epub 2016 Apr 5.


Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma.

Byrne JD, Jajja MR, Schorzman AN, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2200-5. doi: 10.1073/pnas.1600421113. Epub 2016 Feb 8.

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