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Items: 1 to 50 of 109

1.

Bacteriophage-associated genes responsible for the widely divergent phenotypes of variants of Burkholderia pseudomallei strain MSHR5848.

DeShazer D, Lovett S, Richardson J, Koroleva G, Kuehl K, Amemiya K, Sun M, Worsham P, Welkos S.

J Med Microbiol. 2019 Feb;68(2):263-278. doi: 10.1099/jmm.0.000908. Epub 2019 Jan 10.

2.

A MarR family transcriptional regulator and subinhibitory antibiotics regulate type VI secretion gene clusters in Burkholderia pseudomallei.

Losada L, Shea AA, DeShazer D.

Microbiology. 2018 Sep;164(9):1196-1211. doi: 10.1099/mic.0.000697. Epub 2018 Jul 27.

PMID:
30052173
3.

The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy.

Chua J, Fisher NA, Falcinelli SD, DeShazer D, Friedlander AM.

J Vis Exp. 2017 Nov 24;(129). doi: 10.3791/56491.

PMID:
29286449
4.

Development of Subunit Vaccines That Provide High-Level Protection and Sterilizing Immunity against Acute Inhalational Melioidosis.

Burtnick MN, Shaffer TL, Ross BN, Muruato LA, Sbrana E, DeShazer D, Torres AG, Brett PJ.

Infect Immun. 2017 Dec 19;86(1). pii: e00724-17. doi: 10.1128/IAI.00724-17. Print 2018 Jan.

5.

AOAC SMPR 2016.010.

Gee J, Arce J, Beck LC, Blank TR, Blyn L, Cahall R, Clark AJ, Currie B, Damer K, Davenport M, DeShazer D, Johns M, Keim PS, Kiss K, Lesho M, Lin N, Morse SA, Naraghi-Arani P, Ozanich R, Roberto F, Rozak D, Sahl J, Schaefer F, Schutzer S, Schweizer HP, Sozhamannan S, Tuanyok A, Coates S.

J AOAC Int. 2017 Jan 1;100(1):261-265. doi: 10.5740/jaoacint.SMPR2016.010. No abstract available.

PMID:
28825553
6.

pH Alkalinization by Chloroquine Suppresses Pathogenic Burkholderia Type 6 Secretion System 1 and Multinucleated Giant Cells.

Chua J, Senft JL, Lockett SJ, Brett PJ, Burtnick MN, DeShazer D, Friedlander AM.

Infect Immun. 2016 Dec 29;85(1). pii: e00586-16. doi: 10.1128/IAI.00586-16. Print 2017 Jan.

7.

DBSecSys 2.0: a database of Burkholderia mallei and Burkholderia pseudomallei secretion systems.

Memišević V, Kumar K, Zavaljevski N, DeShazer D, Wallqvist A, Reifman J.

BMC Bioinformatics. 2016 Sep 20;17:387. doi: 10.1186/s12859-016-1242-z.

8.

Mining host-pathogen protein interactions to characterize Burkholderia mallei infectivity mechanisms.

Memišević V, Zavaljevski N, Rajagopala SV, Kwon K, Pieper R, DeShazer D, Reifman J, Wallqvist A.

PLoS Comput Biol. 2015 Mar 4;11(3):e1004088. doi: 10.1371/journal.pcbi.1004088. eCollection 2015 Mar.

9.

Melioidosis: molecular aspects of pathogenesis.

Stone JK, DeShazer D, Brett PJ, Burtnick MN.

Expert Rev Anti Infect Ther. 2014 Dec;12(12):1487-99. doi: 10.1586/14787210.2014.970634. Epub 2014 Oct 14. Review.

10.

DBSecSys: a database of Burkholderia mallei secretion systems.

Memišević V, Kumar K, Cheng L, Zavaljevski N, DeShazer D, Wallqvist A, Reifman J.

BMC Bioinformatics. 2014 Jul 16;15:244. doi: 10.1186/1471-2105-15-244.

11.

The chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity.

Biggins JB, Kang HS, Ternei MA, DeShazer D, Brady SF.

J Am Chem Soc. 2014 Jul 2;136(26):9484-90. doi: 10.1021/ja504617n. Epub 2014 Jun 24.

12.

Proteomic analysis of the Burkholderia pseudomallei type II secretome reveals hydrolytic enzymes, novel proteins, and the deubiquitinase TssM.

Burtnick MN, Brett PJ, DeShazer D.

Infect Immun. 2014 Aug;82(8):3214-26. doi: 10.1128/IAI.01739-14. Epub 2014 May 27.

13.

A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages.

Pegoraro G, Eaton BP, Ulrich RL, Lane DJ, Ojeda JF, Bavari S, DeShazer D, Panchal RG.

BMC Microbiol. 2014 Apr 22;14:98. doi: 10.1186/1471-2180-14-98.

14.

Characterization of the Burkholderia thailandensis SOS response by using whole-transcriptome shotgun sequencing.

Ulrich RL, Deshazer D, Kenny TA, Ulrich MP, Moravusova A, Opperman T, Bavari S, Bowlin TL, Moir DT, Panchal RG.

Appl Environ Microbiol. 2013 Oct;79(19):5830-43. doi: 10.1128/AEM.00538-13. Epub 2013 Jul 19.

15.

Novel Burkholderia mallei virulence factors linked to specific host-pathogen protein interactions.

Memisević V, Zavaljevski N, Pieper R, Rajagopala SV, Kwon K, Townsend K, Yu C, Yu X, DeShazer D, Reifman J, Wallqvist A.

Mol Cell Proteomics. 2013 Nov;12(11):3036-51. doi: 10.1074/mcp.M113.029041. Epub 2013 Jun 24.

16.

φX216, a P2-like bacteriophage with broad Burkholderia pseudomallei and B. mallei strain infectivity.

Kvitko BH, Cox CR, DeShazer D, Johnson SL, Voorhees KJ, Schweizer HP.

BMC Microbiol. 2012 Dec 7;12:289. doi: 10.1186/1471-2180-12-289.

17.

Distinct human antibody response to the biological warfare agent Burkholderia mallei.

Varga JJ, Vigil A, DeShazer D, Waag DM, Felgner P, Goldberg JB.

Virulence. 2012 Oct 1;3(6):510-4. doi: 10.4161/viru.22056. Epub 2012 Oct 1.

18.

The Madagascar hissing cockroach as a novel surrogate host for Burkholderia pseudomallei, B. mallei and B. thailandensis.

Fisher NA, Ribot WJ, Applefeld W, DeShazer D.

BMC Microbiol. 2012 Jun 22;12:117. doi: 10.1186/1471-2180-12-117.

19.

Humoral immune responses in a human case of glanders.

Waag DM, England MJ, DeShazer D.

Clin Vaccine Immunol. 2012 May;19(5):814-6. doi: 10.1128/CVI.05567-11. Epub 2012 Mar 7.

20.

The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei.

Burtnick MN, Brett PJ, Harding SV, Ngugi SA, Ribot WJ, Chantratita N, Scorpio A, Milne TS, Dean RE, Fritz DL, Peacock SJ, Prior JL, Atkins TP, Deshazer D.

Infect Immun. 2011 Apr;79(4):1512-25. doi: 10.1128/IAI.01218-10. Epub 2011 Feb 7.

21.

Burkholderia thailandensis oacA mutants facilitate the expression of Burkholderia mallei-like O polysaccharides.

Brett PJ, Burtnick MN, Heiss C, Azadi P, DeShazer D, Woods DE, Gherardini FC.

Infect Immun. 2011 Feb;79(2):961-9. doi: 10.1128/IAI.01023-10. Epub 2010 Nov 29.

22.

Genetic and phenotypic diversity in Burkholderia: contributions by prophage and phage-like elements.

Ronning CM, Losada L, Brinkac L, Inman J, Ulrich RL, Schell M, Nierman WC, Deshazer D.

BMC Microbiol. 2010 Jul 28;10:202. doi: 10.1186/1471-2180-10-202.

23.

Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis.

Galyov EE, Brett PJ, DeShazer D.

Annu Rev Microbiol. 2010;64:495-517. doi: 10.1146/annurev.micro.112408.134030. Review.

PMID:
20528691
24.

Continuing evolution of Burkholderia mallei through genome reduction and large-scale rearrangements.

Losada L, Ronning CM, DeShazer D, Woods D, Fedorova N, Kim HS, Shabalina SA, Pearson TR, Brinkac L, Tan P, Nandi T, Crabtree J, Badger J, Beckstrom-Sternberg S, Saqib M, Schutzer SE, Keim P, Nierman WC.

Genome Biol Evol. 2010 Jan 22;2:102-16. doi: 10.1093/gbe/evq003.

25.

Molecular epidemiology of glanders, Pakistan.

Hornstra H, Pearson T, Georgia S, Liguori A, Dale J, Price E, O'Neill M, Deshazer D, Muhammad G, Saqib M, Naureen A, Keim P.

Emerg Infect Dis. 2009 Dec;15(12):2036-9. doi: 10.3201/eid1512.090738.

26.

Burkholderia mallei cluster 1 type VI secretion mutants exhibit growth and actin polymerization defects in RAW 264.7 murine macrophages.

Burtnick MN, DeShazer D, Nair V, Gherardini FC, Brett PJ.

Infect Immun. 2010 Jan;78(1):88-99. doi: 10.1128/IAI.00985-09. Epub 2009 Nov 2.

27.

Burkholderia mallei tssM encodes a putative deubiquitinase that is secreted and expressed inside infected RAW 264.7 murine macrophages.

Shanks J, Burtnick MN, Brett PJ, Waag DM, Spurgers KB, Ribot WJ, Schell MA, Panchal RG, Gherardini FC, Wilkinson KD, Deshazer D.

Infect Immun. 2009 Apr;77(4):1636-48. doi: 10.1128/IAI.01339-08. Epub 2009 Jan 21.

28.

A disruption of ctpA encoding carboxy-terminal protease attenuates Burkholderia mallei and induces partial protection in CD1 mice.

Bandara AB, DeShazer D, Inzana TJ, Sriranganathan N, Schurig GG, Boyle SM.

Microb Pathog. 2008 Sep;45(3):207-16. doi: 10.1016/j.micpath.2008.05.005. Epub 2008 Jun 3.

PMID:
18614331
29.

Management of accidental laboratory exposure to Burkholderia pseudomallei and B. mallei.

Peacock SJ, Schweizer HP, Dance DA, Smith TL, Gee JE, Wuthiekanun V, DeShazer D, Steinmetz I, Tan P, Currie BJ.

Emerg Infect Dis. 2008 Jul;14(7):e2. doi: 10.3201/eid1407.071501.

30.

Application of carbohydrate microarray technology for the detection of Burkholderia pseudomallei, Bacillus anthracis and Francisella tularensis antibodies.

Parthasarathy N, Saksena R, Kováč P, Deshazer D, Peacock SJ, Wuthiekanun V, Heine HS, Friedlander AM, Cote CK, Welkos SL, Adamovicz JJ, Bavari S, Waag DM.

Carbohydr Res. 2008 Nov 3;343(16):2783-8. doi: 10.1016/j.carres.2008.05.021. Epub 2008 Jun 14.

PMID:
18558401
31.

Characterization of clinically-attenuated Burkholderia mallei by whole genome sequencing: candidate strain for exclusion from Select Agent lists.

Schutzer SE, Schlater LR, Ronning CM, DeShazer D, Luft BJ, Dunn JJ, Ravel J, Fraser-Liggett CM, Nierman WC.

PLoS One. 2008 Apr 30;3(4):e2058. doi: 10.1371/journal.pone.0002058.

32.

Comparative genomics and an insect model rapidly identify novel virulence genes of Burkholderia mallei.

Schell MA, Lipscomb L, DeShazer D.

J Bacteriol. 2008 Apr;190(7):2306-13. doi: 10.1128/JB.01735-07. Epub 2008 Jan 25.

34.

Detection of the host immune response to Burkholderia mallei heat-shock proteins GroEL and DnaK in a glanders patient and infected mice.

Amemiya K, Meyers JL, Deshazer D, Riggins RN, Halasohoris S, England M, Ribot W, Norris SL, Waag DM.

Diagn Microbiol Infect Dis. 2007 Oct;59(2):137-47.

PMID:
17908615
35.

Type VI secretion is a major virulence determinant in Burkholderia mallei.

Schell MA, Ulrich RL, Ribot WJ, Brueggemann EE, Hines HB, Chen D, Lipscomb L, Kim HS, Mrázek J, Nierman WC, Deshazer D.

Mol Microbiol. 2007 Jun;64(6):1466-85.

36.
37.

Tandem repeat regions within the Burkholderia pseudomallei genome and their application for high resolution genotyping.

U'Ren JM, Schupp JM, Pearson T, Hornstra H, Friedman CL, Smith KL, Daugherty RR, Rhoton SD, Leadem B, Georgia S, Cardon M, Huynh LY, DeShazer D, Harvey SP, Robison R, Gal D, Mayo MJ, Wagner D, Currie BJ, Keim P.

BMC Microbiol. 2007 Mar 30;7:23.

38.

Genome sequence alterations detected upon passage of Burkholderia mallei ATCC 23344 in culture and in mammalian hosts.

Romero CM, DeShazer D, Feldblyum T, Ravel J, Woods D, Kim HS, Yu Y, Ronning CM, Nierman WC.

BMC Genomics. 2006 Sep 5;7:228.

39.

Polysaccharide microarray technology for the detection of Burkholderia pseudomallei and Burkholderia mallei antibodies.

Parthasarathy N, DeShazer D, England M, Waag DM.

Diagn Microbiol Infect Dis. 2006 Nov;56(3):329-32. Epub 2006 Jun 12. Erratum in: Diagn Microbiol Infect Dis. 2008 Sep;62(1):117.

PMID:
16765554
40.

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis.

Yu Y, Kim HS, Chua HH, Lin CH, Sim SH, Lin D, Derr A, Engels R, DeShazer D, Birren B, Nierman WC, Tan P.

BMC Microbiol. 2006 May 26;6:46.

41.

Synchronization and symmetry breaking in mutually coupled fiber lasers.

Rogers-Dakin EA, García-Ojalvo J, DeShazer DJ, Roy R.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Apr;73(4 Pt 2):045201. Epub 2006 Apr 11.

PMID:
16711866
42.
43.
44.
45.

Aerogenic vaccination with a Burkholderia mallei auxotroph protects against aerosol-initiated glanders in mice.

Ulrich RL, Amemiya K, Waag DM, Roy CJ, DeShazer D.

Vaccine. 2005 Mar 14;23(16):1986-92.

PMID:
15734072
46.

Quorum sensing: a transcriptional regulatory system involved in the pathogenicity of Burkholderia mallei.

Ulrich RL, Deshazer D, Hines HB, Jeddeloh JA.

Infect Immun. 2004 Nov;72(11):6589-96.

47.

Role of quorum sensing in the pathogenicity of Burkholderia pseudomallei.

Ulrich RL, Deshazer D, Brueggemann EE, Hines HB, Oyston PC, Jeddeloh JA.

J Med Microbiol. 2004 Nov;53(Pt 11):1053-64.

PMID:
15496380
48.

Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei.

Holden MT, Titball RW, Peacock SJ, Cerdeño-Tárraga AM, Atkins T, Crossman LC, Pitt T, Churcher C, Mungall K, Bentley SD, Sebaihia M, Thomson NR, Bason N, Beacham IR, Brooks K, Brown KA, Brown NF, Challis GL, Cherevach I, Chillingworth T, Cronin A, Crossett B, Davis P, DeShazer D, Feltwell T, Fraser A, Hance Z, Hauser H, Holroyd S, Jagels K, Keith KE, Maddison M, Moule S, Price C, Quail MA, Rabbinowitsch E, Rutherford K, Sanders M, Simmonds M, Songsivilai S, Stevens K, Tumapa S, Vesaratchavest M, Whitehead S, Yeats C, Barrell BG, Oyston PC, Parkhill J.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14240-5. Epub 2004 Sep 17.

49.

Structural flexibility in the Burkholderia mallei genome.

Nierman WC, DeShazer D, Kim HS, Tettelin H, Nelson KE, Feldblyum T, Ulrich RL, Ronning CM, Brinkac LM, Daugherty SC, Davidsen TD, Deboy RT, Dimitrov G, Dodson RJ, Durkin AS, Gwinn ML, Haft DH, Khouri H, Kolonay JF, Madupu R, Mohammoud Y, Nelson WC, Radune D, Romero CM, Sarria S, Selengut J, Shamblin C, Sullivan SA, White O, Yu Y, Zafar N, Zhou L, Fraser CM.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14246-51. Epub 2004 Sep 17.

50.

Contribution of gene loss to the pathogenic evolution of Burkholderia pseudomallei and Burkholderia mallei.

Moore RA, Reckseidler-Zenteno S, Kim H, Nierman W, Yu Y, Tuanyok A, Warawa J, DeShazer D, Woods DE.

Infect Immun. 2004 Jul;72(7):4172-87.

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