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Items: 22


Toll-like Receptor-6 Signaling Prevents Inflammation and Impacts Composition of the Microbiota During Inflammation-Induced Colorectal Cancer.

Kim JH, Kordahi MC, Chac D, DePaolo RW.

Cancer Prev Res (Phila). 2020 Jan;13(1):25-40. doi: 10.1158/1940-6207.CAPR-19-0286. Epub 2019 Nov 26.


Commensal Bacteria Decontaminating Your Diet.

Kordahi MC, DePaolo RW.

Cell Host Microbe. 2019 Oct 9;26(4):446-448. doi: 10.1016/j.chom.2019.09.013.


Innate Recognition of the Microbiota by TLR1 Promotes Epithelial Homeostasis and Prevents Chronic Inflammation.

Kamdar K, Johnson AMF, Chac D, Myers K, Kulur V, Truevillian K, DePaolo RW.

J Immunol. 2018 Jul 1;201(1):230-242. doi: 10.4049/jimmunol.1701216. Epub 2018 May 23.


Infectious Scarring: Setting the Trigger for Intestinal Inflammation.

Johnson AMF, DePaolo RW.

Cell Host Microbe. 2018 Feb 14;23(2):154-156. doi: 10.1016/j.chom.2018.01.017.


Window-of-opportunity: neonatal gut microbiota and atopy.

Johnson AMF, DePaolo RW.

Hepatobiliary Surg Nutr. 2017 Jun;6(3):190-192. doi: 10.21037/hbsn.2017.03.05. No abstract available.


Predictive value of TLR7 polymorphism for cetuximab-based chemotherapy in patients with metastatic colorectal cancer.

Okazaki S, Stintzing S, Sunakawa Y, Cao S, Zhang W, Yang D, Ning Y, Matsusaka S, Berger MD, Miyamoto Y, Suenaga M, Schirripa M, West JD, Gopez R, Akihito T, Ichikawa W, Heinemann V, DePaolo RW, Lenz HJ.

Int J Cancer. 2017 Sep 15;141(6):1222-1230. doi: 10.1002/ijc.30810. Epub 2017 Jun 21.


Clinical Significance of TLR1 I602S Polymorphism for Patients with Metastatic Colorectal Cancer Treated with FOLFIRI plus Bevacizumab.

Okazaki S, Loupakis F, Stintzing S, Cao S, Zhang W, Yang D, Ning Y, Sunakawa Y, Stremitzer S, Matsusaka S, Berger MD, Parekh A, West JD, Miyamoto Y, Suenaga M, Schirripa M, Cremolini C, Falcone A, Heinemann V, DePaolo RW, Lenz HJ.

Mol Cancer Ther. 2016 Jul;15(7):1740-5. doi: 10.1158/1535-7163.MCT-15-0931. Epub 2016 May 11.


Genetic and Metabolic Signals during Acute Enteric Bacterial Infection Alter the Microbiota and Drive Progression to Chronic Inflammatory Disease.

Kamdar K, Khakpour S, Chen J, Leone V, Brulc J, Mangatu T, Antonopoulos DA, Chang EB, Kahn SA, Kirschner BS, Young G, DePaolo RW.

Cell Host Microbe. 2016 Jan 13;19(1):21-31. doi: 10.1016/j.chom.2015.12.006.


Retinoic acid can exacerbate T cell intrinsic TLR2 activation to promote tolerance.

Nguyen V, Pearson K, Kim JH, Kamdar K, DePaolo RW.

PLoS One. 2015 Mar 31;10(3):e0118875. doi: 10.1371/journal.pone.0118875. eCollection 2015.


Genetic variants associated with Crohn's disease.

Michail S, Bultron G, Depaolo RW.

Appl Clin Genet. 2013 Jul 16;6:25-32. doi: 10.2147/TACG.S33966. Print 2013.


TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica.

Sugiura Y, Kamdar K, Khakpour S, Young G, Karpus WJ, DePaolo RW.

Mucosal Immunol. 2013 Nov;6(6):1101-9. doi: 10.1038/mi.2013.5. Epub 2013 Feb 27.


Toll-like receptor signaling and regulation of intestinal immunity.

Kamdar K, Nguyen V, DePaolo RW.

Virulence. 2013 Apr 1;4(3):207-12. doi: 10.4161/viru.23354. Epub 2013 Jan 18. Review.


A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.

DePaolo RW, Kamdar K, Khakpour S, Sugiura Y, Wang W, Jabri B.

J Exp Med. 2012 Jul 30;209(8):1437-44. doi: 10.1084/jem.20112339. Epub 2012 Jul 9.


Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens.

DePaolo RW, Abadie V, Tang F, Fehlner-Peach H, Hall JA, Wang W, Marietta EV, Kasarda DD, Waldmann TA, Murray JA, Semrad C, Kupfer SS, Belkaid Y, Guandalini S, Jabri B.

Nature. 2011 Mar 10;471(7337):220-4. doi: 10.1038/nature09849. Epub 2011 Feb 9.


Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis.

Elhofy A, Depaolo RW, Lira SA, Lukacs NW, Karpus WJ.

J Neuroimmunol. 2009 Aug 18;213(1-2):91-9. doi: 10.1016/j.jneuroim.2009.05.011. Epub 2009 Jun 17.


Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis.

Depaolo RW, Tang F, Kim I, Han M, Levin N, Ciletti N, Lin A, Anderson D, Schneewind O, Jabri B.

Cell Host Microbe. 2008 Oct 16;4(4):350-61. doi: 10.1016/j.chom.2008.09.004.


Immunogenicity and protective immunity against bubonic plague and pneumonic plague by immunization of mice with the recombinant V10 antigen, a variant of LcrV.

DeBord KL, Anderson DM, Marketon MM, Overheim KA, DePaolo RW, Ciletti NA, Jabri B, Schneewind O.

Infect Immun. 2006 Aug;74(8):4910-4.


The chemokine CCL2 is required for control of murine gastric Salmonella enterica infection.

Depaolo RW, Lathan R, Rollins BJ, Karpus WJ.

Infect Immun. 2005 Oct;73(10):6514-22.


Plague bacteria target immune cells during infection.

Marketon MM, DePaolo RW, DeBord KL, Jabri B, Schneewind O.

Science. 2005 Sep 9;309(5741):1739-41. Epub 2005 Jul 28.


LcrV plague vaccine with altered immunomodulatory properties.

Overheim KA, Depaolo RW, Debord KL, Morrin EM, Anderson DM, Green NM, Brubaker RR, Jabri B, Schneewind O.

Infect Immun. 2005 Aug;73(8):5152-9.


CCR5 regulates high dose oral tolerance by modulating CC chemokine ligand 2 levels in the GALT.

DePaolo RW, Lathan R, Karpus WJ.

J Immunol. 2004 Jul 1;173(1):314-20.


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