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Items: 17

1.

Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane.

DeLalio LJ, Billaud M, Ruddiman CA, Johnstone SR, Butcher JT, Wolpe AG, Jin X, Keller TCS 4th, Keller AS, Rivière T, Good ME, Best AK, Lohman AW, Swayne LA, Penuela S, Thompson RJ, Lampe PD, Yeager M, Isakson BE.

J Biol Chem. 2019 Apr 26;294(17):6940-6956. doi: 10.1074/jbc.RA118.006982. Epub 2019 Feb 27.

PMID:
30814251
2.

Ablation of both Cx40 and Panx1 results in similar cardiovascular phenotypes exhibited in Cx40 knockout mice.

Novielli-Kuntz NM, Jelen M, Barr K, DeLalio LJ, Feng Q, Isakson BE, Gros R, Laird DW.

Biosci Rep. 2019 Feb 27;39(2). pii: BSR20182350. doi: 10.1042/BSR20182350. Print 2019 Feb 28.

3.

Vascular Smooth Muscle Remodeling in Conductive and Resistance Arteries in Hypertension.

Brown IAM, Diederich L, Good ME, DeLalio LJ, Murphy SA, Cortese-Krott MM, Hall JL, Le TH, Isakson BE.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):1969-1985. doi: 10.1161/ATVBAHA.118.311229.

PMID:
30354262
4.

Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure.

DeLalio LJ, Keller AS, Chen J, Boyce AKJ, Artamonov MV, Askew-Page HR, Keller TCS 4th, Johnstone SR, Weaver RB, Good ME, Murphy SA, Best AK, Mintz EL, Penuela S, Greenwood IA, Machado RF, Somlyo AV, Swayne LA, Minshall RD, Isakson BE.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2065-2078. doi: 10.1161/ATVBAHA.118.311290.

PMID:
30026274
5.

Replacement Therapies in Metabolic Disease.

Keller AS, Keller Iv TCS, DeLalio LJ, Shahab G, Yang Y, Murphy SA, Shu X, Isakson BE.

Curr Pharm Biotechnol. 2018;19(5):382-399. doi: 10.2174/1389201019666180619151413. Review.

PMID:
29921204
6.

TRPV4 (Transient Receptor Potential Vanilloid 4) Channel-Dependent Negative Feedback Mechanism Regulates Gq Protein-Coupled Receptor-Induced Vasoconstriction.

Hong K, Cope EL, DeLalio LJ, Marziano C, Isakson BE, Sonkusare SK.

Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):542-554. doi: 10.1161/ATVBAHA.117.310038. Epub 2018 Jan 4.

7.

Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone.

Good ME, Chiu YH, Poon IKH, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett E, Lorenz UM, Desai BN, Jaffe IZ, Bayliss DA, Isakson BE, Ravichandran KS.

Circ Res. 2018 Feb 16;122(4):606-615. doi: 10.1161/CIRCRESAHA.117.312380. Epub 2017 Dec 13.

8.

Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway.

Keller AS, Diederich L, Panknin C, DeLalio LJ, Drake JC, Sherman R, Jackson EK, Yan Z, Kelm M, Cortese-Krott MM, Isakson BE.

Am J Physiol Cell Physiol. 2017 Dec 1;313(6):C593-C603. doi: 10.1152/ajpcell.00178.2017. Epub 2017 Aug 30.

9.

ZP1609/danegaptide and mitochondrial connexin hemichannels: a harbinger for peptide drug design.

DeLalio LJ, Isakson BE.

Br J Pharmacol. 2017 Aug;174(15):2606-2607. doi: 10.1111/bph.13891. Epub 2017 Jul 9.

10.

Pannexin channel and connexin hemichannel expression in vascular function and inflammation.

Begandt D, Good ME, Keller AS, DeLalio LJ, Rowley C, Isakson BE, Figueroa XF.

BMC Cell Biol. 2017 Jan 17;18(Suppl 1):2. doi: 10.1186/s12860-016-0119-3. Review.

11.

Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).

Keller TC 4th, Butcher JT, Broseghini-Filho GB, Marziano C, DeLalio LJ, Rogers S, Ning B, Martin JN, Chechova S, Cabot M, Shu X, Best AK, Good ME, Simão Padilha A, Purdy M, Yeager M, Peirce SM, Hu S, Doctor A, Barrett E, Le TH, Columbus L, Isakson BE.

Hypertension. 2016 Dec;68(6):1494-1503. Epub 2016 Oct 31.

12.

AXL-Mediated Productive Infection of Human Endothelial Cells by Zika Virus.

Liu S, DeLalio LJ, Isakson BE, Wang TT.

Circ Res. 2016 Nov 11;119(11):1183-1189. doi: 10.1161/CIRCRESAHA.116.309866. Epub 2016 Sep 20.

13.

Small Interfering RNA-Mediated Connexin Gene Knockdown in Vascular Endothelial and Smooth Muscle Cells.

Good ME, Begandt D, DeLalio LJ, Johnstone SR, Isakson BE.

Methods Mol Biol. 2016;1437:71-82. doi: 10.1007/978-1-4939-3664-9_5.

PMID:
27207287
14.

Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation.

Lohman AW, Leskov IL, Butcher JT, Johnstone SR, Stokes TA, Begandt D, DeLalio LJ, Best AK, Penuela S, Leitinger N, Ravichandran KS, Stokes KY, Isakson BE.

Nat Commun. 2015 Aug 5;6:7965. doi: 10.1038/ncomms8965.

15.

Emerging concepts regarding pannexin 1 in the vasculature.

Good ME, Begandt D, DeLalio LJ, Keller AS, Billaud M, Isakson BE.

Biochem Soc Trans. 2015 Jun;43(3):495-501. doi: 10.1042/BST20150045. Review.

16.

Direct effects of hypoxia and nitric oxide on ecdysone secretion by insect prothoracic glands.

DeLalio LJ, Dion SM, Bootes AM, Smith WA.

J Insect Physiol. 2015 May;76:56-66. doi: 10.1016/j.jinsphys.2015.02.009. Epub 2015 Mar 4.

PMID:
25747870
17.

A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells.

Billaud M, Chiu YH, Lohman AW, Parpaite T, Butcher JT, Mutchler SM, DeLalio LJ, Artamonov MV, Sandilos JK, Best AK, Somlyo AV, Thompson RJ, Le TH, Ravichandran KS, Bayliss DA, Isakson BE.

Sci Signal. 2015 Feb 17;8(364):ra17. doi: 10.1126/scisignal.2005824.

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