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Items: 14


Lysyl oxidase enzymes mediate TGF-β1-induced fibrotic phenotypes in human skin-like tissues.

Huang M, Liu Z, Baugh L, DeFuria J, Maione A, Smith A, Kashpur O, Black Iii LD, Georgakoudi I, Whitfield ML, Garlick J.

Lab Invest. 2019 Apr;99(4):514-527. doi: 10.1038/s41374-018-0159-8. Epub 2018 Dec 19.


Dietary supplementation with blueberry partially restores T-cell-mediated function in high-fat-diet-induced obese mice.

Lewis ED, Ren Z, DeFuria J, Obin MS, Meydani SN, Wu D.

Br J Nutr. 2018 Jun;119(12):1393-1399. doi: 10.1017/S0007114518001034.


Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production.

Ip B, Cilfone NA, Belkina AC, DeFuria J, Jagannathan-Bogdan M, Zhu M, Kuchibhatla R, McDonnell ME, Xiao Q, Kepler TB, Apovian CM, Lauffenburger DA, Nikolajczyk BS.

Obesity (Silver Spring). 2016 Jan;24(1):102-12. doi: 10.1002/oby.21243. Epub 2015 Nov 18.


B cells promote obesity-associated periodontitis and oral pathogen-associated inflammation.

Zhu M, Belkina AC, DeFuria J, Carr JD, Van Dyke TE, Gyurko R, Nikolajczyk BS.

J Leukoc Biol. 2014 Aug;96(2):349-57. doi: 10.1189/jlb.4A0214-095R. Epub 2014 Apr 29.


Extended lifespan and reduced adiposity in mice lacking the FAT10 gene.

Canaan A, DeFuria J, Perelman E, Schultz V, Seay M, Tuck D, Flavell RA, Snyder MP, Obin MS, Weissman SM.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5313-8. doi: 10.1073/pnas.1323426111. Epub 2014 Mar 24.


Deletion of TNF-like weak inducer of apoptosis (TWEAK) protects mice from adipose and systemic impacts of severe obesity.

Bennett G, Strissel KJ, DeFuria J, Wang J, Wu D, Burkly LC, Obin MS.

Obesity (Silver Spring). 2014 Jun;22(6):1485-94. doi: 10.1002/oby.20726. Epub 2014 Mar 8.


B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile.

DeFuria J, Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, Carr JD, Nersesova YR, Markham D, Strissel KJ, Watkins AA, Zhu M, Allen J, Bouchard J, Toraldo G, Jasuja R, Obin MS, McDonnell ME, Apovian C, Denis GV, Nikolajczyk BS.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5133-8. doi: 10.1073/pnas.1215840110. Epub 2013 Mar 11.


Adipose tissue inflammation and reduced insulin sensitivity in ovariectomized mice occurs in the absence of increased adiposity.

Vieira Potter VJ, Strissel KJ, Xie C, Chang E, Bennett G, Defuria J, Obin MS, Greenberg AS.

Endocrinology. 2012 Sep;153(9):4266-77. doi: 10.1210/en.2011-2006. Epub 2012 Jul 9.


T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice.

Strissel KJ, DeFuria J, Shaul ME, Bennett G, Greenberg AS, Obin MS.

Obesity (Silver Spring). 2010 Oct;18(10):1918-25. doi: 10.1038/oby.2010.1. Epub 2010 Jan 28.


Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity.

Danilova OV, Tai AK, Mele DA, Beinborn M, Leiter AB, Greenberg AS, Perfield JW 2nd, Defuria J, Singru PS, Lechan RM, Huber BT.

Endocrinology. 2009 Dec;150(12):5240-8. doi: 10.1210/en.2009-0386. Epub 2009 Oct 9.


Dietary blueberry attenuates whole-body insulin resistance in high fat-fed mice by reducing adipocyte death and its inflammatory sequelae.

DeFuria J, Bennett G, Strissel KJ, Perfield JW 2nd, Milbury PE, Greenberg AS, Obin MS.

J Nutr. 2009 Aug;139(8):1510-6. doi: 10.3945/jn.109.105155. Epub 2009 Jun 10.


Adipocyte death, adipose tissue remodeling, and obesity complications.

Strissel KJ, Stancheva Z, Miyoshi H, Perfield JW 2nd, DeFuria J, Jick Z, Greenberg AS, Obin MS.

Diabetes. 2007 Dec;56(12):2910-8. Epub 2007 Sep 11.

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