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Items: 13

1.

Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens.

DeFalco J, Harbell M, Manning-Bog A, Baia G, Scholz A, Millare B, Sumi M, Zhang D, Chu F, Dowd C, Zuno-Mitchell P, Kim D, Leung Y, Jiang S, Tang X, Williamson KS, Chen X, Carroll SM, Espiritu Santo G, Haaser N, Nguyen N, Giladi E, Minor D, Tan YC, Sokolove JB, Steinman L, Serafini TA, Cavet G, Greenberg NM, Glanville J, Volkmuth W, Emerling DE, Robinson WH.

Clin Immunol. 2018 Feb;187:37-45. doi: 10.1016/j.clim.2017.10.002. Epub 2017 Oct 12.

2.

Identification of orally-bioavailable antagonists of the TRPV4 ion-channel.

Wei ZL, Nguyen MT, O'Mahony DJ, Acevedo A, Zipfel S, Zhang Q, Liu L, Dourado M, Chi C, Yip V, DeFalco J, Gustafson A, Emerling DE, Kelly MG, Kincaid J, Vincent F, Duncton MA.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. doi: 10.1016/j.bmcl.2015.06.098. Epub 2015 Jul 6.

PMID:
26235950
3.

TRPM8 biology and medicinal chemistry.

DeFalco J, Duncton MA, Emerling D.

Curr Top Med Chem. 2011;11(17):2237-52. Review.

PMID:
21671871
4.

5-benzyloxytryptamine as an antagonist of TRPM8.

DeFalco J, Steiger D, Dourado M, Emerling D, Duncton MA.

Bioorg Med Chem Lett. 2010 Dec 1;20(23):7076-9. doi: 10.1016/j.bmcl.2010.09.099. Epub 2010 Sep 22.

PMID:
20965726
5.

Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically.

Stanley S, Pinto S, Segal J, PĂ©rez CA, Viale A, DeFalco J, Cai X, Heisler LK, Friedman JM.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7024-9. doi: 10.1073/pnas.1002790107. Epub 2010 Mar 29.

6.

Oxime derivatives related to AP18: Agonists and antagonists of the TRPA1 receptor.

Defalco J, Steiger D, Gustafson A, Emerling DE, Kelly MG, Duncton MA.

Bioorg Med Chem Lett. 2010 Jan 1;20(1):276-9. doi: 10.1016/j.bmcl.2009.10.113. Epub 2009 Oct 30.

PMID:
19945872
7.

Functional assessment of temperature-gated ion-channel activity using a real-time PCR machine.

Reubish D, Emerling D, Defalco J, Steiger D, Victoria C, Vincent F.

Biotechniques. 2009 Sep;47(3):iii-ix. doi: 10.2144/000113198.

8.

Identification and characterization of novel TRPV4 modulators.

Vincent F, Acevedo A, Nguyen MT, Dourado M, DeFalco J, Gustafson A, Spiro P, Emerling DE, Kelly MG, Duncton MA.

Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4. doi: 10.1016/j.bbrc.2009.09.007. Epub 2009 Sep 6.

PMID:
19737537
9.

Virus-assisted mapping of neural inputs to a feeding center in the hypothalamus.

DeFalco J, Tomishima M, Liu H, Zhao C, Cai X, Marth JD, Enquist L, Friedman JM.

Science. 2001 Mar 30;291(5513):2608-13.

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The heart of the matter: Ottawa surgeons make history and create a controversy.

Defalco J.

CMAJ. 1986 Sep 1;135(5):510-3. No abstract available.

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