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Items: 6


p53 and ΔNp63α Coregulate the Transcriptional and Cellular Response to TGFβ and BMP Signals.

Balboni AL, Cherukuri P, Ung M, DeCastro AJ, Cheng C, DiRenzo J.

Mol Cancer Res. 2015 Apr;13(4):732-42. doi: 10.1158/1541-7786.MCR-14-0152-T. Epub 2015 Feb 19.


ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to regulate breast cancer stem cell activity and chemotaxis.

DeCastro AJ, Cherukuri P, Balboni A, DiRenzo J.

Mol Cancer Ther. 2015 Jan;14(1):225-35. doi: 10.1158/1535-7163.MCT-14-0194. Epub 2014 Nov 5.


MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition.

DeCastro AJ, Dunphy KA, Hutchinson J, Balboni AL, Cherukuri P, Jerry DJ, DiRenzo J.

Cell Death Dis. 2013 Feb 28;4:e514. doi: 10.1038/cddis.2013.37.


ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.

Balboni AL, Hutchinson JA, DeCastro AJ, Cherukuri P, Liby K, Sporn MB, Schwartz GN, Wells WA, Sempere LF, Yu PB, DiRenzo J.

Cancer Res. 2013 Jan 15;73(2):1020-30. doi: 10.1158/0008-5472.CAN-12-2862. Epub 2012 Dec 14.


Phosphorylation of ΔNp63α via a novel TGFβ/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGFβ.

Cherukuri P, DeCastro AJ, Balboni AL, Downey SL, Liu JY, Hutchinson JA, DiRenzo J.

PLoS One. 2012;7(11):e50066. doi: 10.1371/journal.pone.0050066. Epub 2012 Nov 16.


Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats.

Paul S, DeCastro AJ, Lee HJ, Smolarek AK, So JY, Simi B, Wang CX, Zhou R, Rimando AM, Suh N.

Carcinogenesis. 2010 Jul;31(7):1272-8. doi: 10.1093/carcin/bgq004. Epub 2010 Jan 8.

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