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Items: 1 to 50 of 141

1.

Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB.

Schade AE, Oser MG, Nicholson HE, DeCaprio JA.

Oncogene. 2019 Jun;38(25):4962-4976. doi: 10.1038/s41388-019-0767-9. Epub 2019 Mar 4.

PMID:
30833638
2.

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.

Menon VR, Ananthapadmanabhan V, Swanson S, Saini S, Sesay F, Yakovlev V, Florens L, DeCaprio JA, Washburn MP, Dozmorov M, Litovchick L.

Cell Cycle. 2019 Mar;18(5):531-551. doi: 10.1080/15384101.2019.1577525. Epub 2019 Feb 17.

3.

A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion.

Yin S, Gambe RG, Sun J, Martinez AZ, Cartun ZJ, Regis FFD, Wan Y, Fan J, Brooks AN, Herman SEM, Ten Hacken E, Taylor-Weiner A, Rassenti LZ, Ghia EM, Kipps TJ, Obeng EA, Cibulskis CL, Neuberg D, Campagna DR, Fleming MD, Ebert BL, Wiestner A, Leshchiner I, DeCaprio JA, Getz G, Reed R, Carrasco RD, Wu CJ, Wang L.

Cancer Cell. 2019 Feb 11;35(2):283-296.e5. doi: 10.1016/j.ccell.2018.12.013. Epub 2019 Jan 31.

4.

Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response.

Park DE, Cheng J, Berrios C, Montero J, Cortés-Cros M, Ferretti S, Arora R, Tillgren ML, Gokhale PC, DeCaprio JA.

Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1027-1032. doi: 10.1073/pnas.1818798116. Epub 2018 Dec 31.

PMID:
30598450
5.

SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression.

Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, Ren S, Shulga YV, Beca F, Gan W, Wu F, Lin YM, Zhou X, DeCaprio JA, Beck AH, Lu KP, Huang J, Zhao C, Sun Y, Gao X, Pandolfi PP, Wei W.

Dev Cell. 2019 Feb 11;48(3):329-344.e5. doi: 10.1016/j.devcel.2018.11.035. Epub 2018 Dec 27.

6.

Merkel Cell Carcinoma in the HIV-1/AIDS Patient.

Goldstein RH, DeCaprio JA.

Cancer Treat Res. 2019;177:211-229. doi: 10.1007/978-3-030-03502-0_8.

PMID:
30523626
7.

Contribution of DNA Replication to the FAM111A-Mediated Simian Virus 40 Host Range Phenotype.

Tarnita RM, Wilkie AR, DeCaprio JA.

J Virol. 2018 Dec 10;93(1). pii: e01330-18. doi: 10.1128/JVI.01330-18. Print 2019 Jan 1.

8.

The biology and treatment of Merkel cell carcinoma: current understanding and research priorities.

Harms PW, Harms KL, Moore PS, DeCaprio JA, Nghiem P, Wong MKK, Brownell I; International Workshop on Merkel Cell Carcinoma Research (IWMCC) Working Group.

Nat Rev Clin Oncol. 2018 Dec;15(12):763-776. doi: 10.1038/s41571-018-0103-2. Review.

9.

Cabozantinib in Patients with Advanced Merkel Cell Carcinoma.

Rabinowits G, Lezcano C, Catalano PJ, McHugh P, Becker H, Reilly MM, Huang J, Tyagi A, Thakuria M, Bresler SC, Sholl LM, Shapiro GI, Haddad R, DeCaprio JA.

Oncologist. 2018 Jul;23(7):814-821. doi: 10.1634/theoncologist.2017-0552. Epub 2018 Feb 14.

PMID:
29445030
10.

Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC.

Becker JC, Stang A, Hausen AZ, Fischer N, DeCaprio JA, Tothill RW, Lyngaa R, Hansen UK, Ritter C, Nghiem P, Bichakjian CK, Ugurel S, Schrama D.

Cancer Immunol Immunother. 2018 Mar;67(3):341-351. doi: 10.1007/s00262-017-2099-3. Epub 2017 Nov 30. Review.

11.

Merkel cell carcinoma.

Becker JC, Stang A, DeCaprio JA, Cerroni L, Lebbé C, Veness M, Nghiem P.

Nat Rev Dis Primers. 2017 Oct 26;3:17077. doi: 10.1038/nrdp.2017.77. Review.

12.

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.

Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, Brown M, Howley PM, Padi M, Washburn MP, DeCaprio JA.

PLoS Pathog. 2017 Oct 13;13(10):e1006668. doi: 10.1371/journal.ppat.1006668. eCollection 2017 Oct.

13.

Merkel cell polyomavirus and Merkel cell carcinoma.

DeCaprio JA.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 19;372(1732). pii: 20160276. doi: 10.1098/rstb.2016.0276. Review.

14.

Transcriptional landscape of the human cell cycle.

Liu Y, Chen S, Wang S, Soares F, Fischer M, Meng F, Du Z, Lin C, Meyer C, DeCaprio JA, Brown M, Liu XS, He HH.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3473-3478. doi: 10.1073/pnas.1617636114. Epub 2017 Mar 13.

15.

Merkel Cell Polyomavirus Exhibits Dominant Control of the Tumor Genome and Transcriptome in Virus-Associated Merkel Cell Carcinoma.

Starrett GJ, Marcelus C, Cantalupo PG, Katz JP, Cheng J, Akagi K, Thakuria M, Rabinowits G, Wang LC, Symer DE, Pipas JM, Harris RS, DeCaprio JA.

MBio. 2017 Jan 3;8(1). pii: e02079-16. doi: 10.1128/mBio.02079-16.

16.

Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation.

Berrios C, Padi M, Keibler MA, Park DE, Molla V, Cheng J, Lee SM, Stephanopoulos G, Quackenbush J, DeCaprio JA.

PLoS Pathog. 2016 Nov 23;12(11):e1006020. doi: 10.1371/journal.ppat.1006020. eCollection 2016 Nov.

17.

Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo.

Odajima J, Saini S, Jung P, Ndassa-Colday Y, Ficaro S, Geng Y, Marco E, Michowski W, Wang YE, DeCaprio JA, Litovchick L, Marto J, Sicinski P.

PLoS Genet. 2016 Nov 9;12(11):e1006429. doi: 10.1371/journal.pgen.1006429. eCollection 2016 Nov.

18.

Merkel Cell Carcinoma: A Population Analysis on Survival.

Sridharan V, Muralidhar V, Margalit DN, Tishler RB, DeCaprio JA, Thakuria M, Rabinowits G, Schoenfeld JD.

J Natl Compr Canc Netw. 2016 Oct;14(10):1247-1257.

PMID:
27697979
19.

APC/C and SCF(cyclin F) Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry.

Choudhury R, Bonacci T, Arceci A, Lahiri D, Mills CA, Kernan JL, Branigan TB, DeCaprio JA, Burke DJ, Emanuele MJ.

Cell Rep. 2016 Sep 20;16(12):3359-3372. doi: 10.1016/j.celrep.2016.08.058.

20.

Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.

Fischer M, Grossmann P, Padi M, DeCaprio JA.

Nucleic Acids Res. 2016 Jul 27;44(13):6070-86. doi: 10.1093/nar/gkw523. Epub 2016 Jun 8.

21.

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.

Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W.

Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26.

22.

Does Arabidopsis thaliana DREAM of cell cycle control?

Fischer M, DeCaprio JA.

EMBO J. 2015 Aug 4;34(15):1987-9. doi: 10.15252/embj.201592196. Epub 2015 Jun 18.

23.

Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice.

Spurgeon ME, Cheng J, Bronson RT, Lambert PF, DeCaprio JA.

Cancer Res. 2015 Mar 15;75(6):1068-79. doi: 10.1158/0008-5472.CAN-14-2425. Epub 2015 Jan 16.

24.

Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.

Berrios C, Jung J, Primi B, Wang M, Pedamallu C, Duke F, Marcelus C, Cheng J, Garcea RL, Meyerson M, DeCaprio JA.

J Virol. 2015 Jan;89(1):857-62. doi: 10.1128/JVI.02328-14. Epub 2014 Oct 15.

25.

SMCX and components of the TIP60 complex contribute to E2 regulation of the HPV E6/E7 promoter.

Smith JA, Haberstroh FS, White EA, Livingston DM, DeCaprio JA, Howley PM.

Virology. 2014 Nov;468-470:311-321. doi: 10.1016/j.virol.2014.08.022. Epub 2014 Sep 16.

26.

PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length.

Naetar N, Soundarapandian V, Litovchick L, Goguen KL, Sablina AA, Bowman-Colin C, Sicinski P, Hahn WC, DeCaprio JA, Livingston DM.

Mol Cell. 2014 Jun 19;54(6):932-45. doi: 10.1016/j.molcel.2014.04.023. Epub 2014 May 22.

27.

The DREAM complex in antitumor activity of imatinib mesylate in gastrointestinal stromal tumors.

DeCaprio JA, Duensing A.

Curr Opin Oncol. 2014 Jul;26(4):415-21. doi: 10.1097/CCO.0000000000000090. Review.

28.

Loss of the mammalian DREAM complex deregulates chondrocyte proliferation.

Forristal C, Henley SA, MacDonald JI, Bush JR, Ort C, Passos DT, Talluri S, Ishak CA, Thwaites MJ, Norley CJ, Litovchick L, DeCaprio JA, DiMattia G, Holdsworth DW, Beier F, Dick FA.

Mol Cell Biol. 2014 Jun;34(12):2221-34. doi: 10.1128/MCB.01523-13. Epub 2014 Apr 7.

29.

Nuclear interferon-inducible protein 16 promotes silencing of herpesviral and transfected DNA.

Orzalli MH, Conwell SE, Berrios C, DeCaprio JA, Knipe DM.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4492-501. doi: 10.1073/pnas.1316194110. Epub 2013 Nov 6.

30.

Human papillomavirus type 16 E7 perturbs DREAM to promote cellular proliferation and mitotic gene expression.

DeCaprio JA.

Oncogene. 2014 Jul 31;33(31):4036-8. doi: 10.1038/onc.2013.449. Epub 2013 Oct 28.

31.

The DNA damage and the DNA replication checkpoints converge at the MBF transcription factor.

Ivanova T, Alves-Rodrigues I, Gómez-Escoda B, Dutta C, DeCaprio JA, Rhind N, Hidalgo E, Ayté J.

Mol Biol Cell. 2013 Nov;24(21):3350-7. doi: 10.1091/mbc.E13-05-0257. Epub 2013 Sep 4.

32.

The DREAM complex: master coordinator of cell cycle-dependent gene expression.

Sadasivam S, DeCaprio JA.

Nat Rev Cancer. 2013 Aug;13(8):585-95. doi: 10.1038/nrc3556. Epub 2013 Jul 11. Review. Erratum in: Nat Rev Cancer. 2013 Oct;13(10):752.

33.

The DREAM complex mediates GIST cell quiescence and is a novel therapeutic target to enhance imatinib-induced apoptosis.

Boichuk S, Parry JA, Makielski KR, Litovchick L, Baron JL, Zewe JP, Wozniak A, Mehalek KR, Korzeniewski N, Seneviratne DS, Schöffski P, Debiec-Rychter M, DeCaprio JA, Duensing A.

Cancer Res. 2013 Aug 15;73(16):5120-9. doi: 10.1158/0008-5472.CAN-13-0579. Epub 2013 Jun 20.

34.

Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities.

Cheng J, Rozenblatt-Rosen O, Paulson KG, Nghiem P, DeCaprio JA.

J Virol. 2013 Jun;87(11):6118-26. doi: 10.1128/JVI.00385-13. Epub 2013 Mar 20.

35.

A cornucopia of human polyomaviruses.

DeCaprio JA, Garcea RL.

Nat Rev Microbiol. 2013 Apr;11(4):264-76. doi: 10.1038/nrmicro2992. Epub 2013 Mar 11. Review.

36.

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus.

Rodig SJ, Cheng J, Wardzala J, DoRosario A, Scanlon JJ, Laga AC, Martinez-Fernandez A, Barletta JA, Bellizzi AM, Sadasivam S, Holloway DT, Cooper DJ, Kupper TS, Wang LC, DeCaprio JA.

J Clin Invest. 2012 Dec;122(12):4645-53. doi: 10.1172/JCI64116. Epub 2012 Nov 1.

37.

Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor.

Fine DA, Rozenblatt-Rosen O, Padi M, Korkhin A, James RL, Adelmant G, Yoon R, Guo L, Berrios C, Zhang Y, Calderwood MA, Velmurgan S, Cheng J, Marto JA, Hill DE, Cusick ME, Vidal M, Florens L, Washburn MP, Litovchick L, DeCaprio JA.

PLoS Pathog. 2012;8(10):e1002949. doi: 10.1371/journal.ppat.1002949. Epub 2012 Oct 18.

38.

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M.

Nature. 2012 Jul 26;487(7408):491-5. doi: 10.1038/nature11288.

39.

Viral perturbations of host networks reflect disease etiology.

Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A, Zhao B, Santhanam B, Braun P, Simonis N, Huh KW, Hellner K, Grace M, Chen A, Rubio R, Marto JA, Christakis NA, Kieff E, Roth FP, Roecklein-Canfield J, Decaprio JA, Cusick ME, Quackenbush J, Hill DE, Münger K, Vidal M, Barabási AL.

PLoS Comput Biol. 2012;8(6):e1002531. doi: 10.1371/journal.pcbi.1002531. Epub 2012 Jun 28.

40.

Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface.

Duda DM, Olszewski JL, Tron AE, Hammel M, Lambert LJ, Waddell MB, Mittag T, DeCaprio JA, Schulman BA.

Mol Cell. 2012 Aug 10;47(3):371-82. doi: 10.1016/j.molcel.2012.05.044. Epub 2012 Jun 28.

41.

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.

Min SH, Lau AW, Lee TH, Inuzuka H, Wei S, Huang P, Shaik S, Lee DY, Finn G, Balastik M, Chen CH, Luo M, Tron AE, Decaprio JA, Zhou XZ, Wei W, Lu KP.

Mol Cell. 2012 Jun 29;46(6):771-83. doi: 10.1016/j.molcel.2012.04.012. Epub 2012 May 17.

42.

The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

Tron AE, Arai T, Duda DM, Kuwabara H, Olszewski JL, Fujiwara Y, Bahamon BN, Signoretti S, Schulman BA, DeCaprio JA.

Mol Cell. 2012 Apr 13;46(1):67-78. doi: 10.1016/j.molcel.2012.02.005. Epub 2012 Mar 8.

43.

The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression.

Sadasivam S, Duan S, DeCaprio JA.

Genes Dev. 2012 Mar 1;26(5):474-89. doi: 10.1101/gad.181933.111.

44.

The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.

Müller GA, Quaas M, Schümann M, Krause E, Padi M, Fischer M, Litovchick L, DeCaprio JA, Engeland K.

Nucleic Acids Res. 2012 Feb;40(4):1561-78. doi: 10.1093/nar/gkr793. Epub 2011 Nov 7.

45.

A kinase shRNA screen links LATS2 and the pRB tumor suppressor.

Tschöp K, Conery AR, Litovchick L, Decaprio JA, Settleman J, Harlow E, Dyson N.

Genes Dev. 2011 Apr 15;25(8):814-30. doi: 10.1101/gad.2000211.

46.

DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.

Litovchick L, Florens LA, Swanson SK, Washburn MP, DeCaprio JA.

Genes Dev. 2011 Apr 15;25(8):801-13. doi: 10.1101/gad.2034211.

47.

Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.

Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W.

Mol Cell. 2010 Sep 10;39(5):797-808. doi: 10.1016/j.molcel.2010.08.016.

48.

Does detection of Merkel cell polyomavirus in Merkel cell carcinoma provide prognostic information?

DeCaprio JA.

J Natl Cancer Inst. 2009 Jul 1;101(13):905-7. doi: 10.1093/jnci/djp162. Epub 2009 Jun 17. No abstract available.

PMID:
19535772
49.

Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.

Cheng J, DeCaprio JA, Fluck MM, Schaffhausen BS.

Semin Cancer Biol. 2009 Aug;19(4):218-28. doi: 10.1016/j.semcancer.2009.03.002. Epub 2009 Mar 31. Review.

50.

A compendium of potential biomarkers of pancreatic cancer.

Harsha HC, Kandasamy K, Ranganathan P, Rani S, Ramabadran S, Gollapudi S, Balakrishnan L, Dwivedi SB, Telikicherla D, Selvan LD, Goel R, Mathivanan S, Marimuthu A, Kashyap M, Vizza RF, Mayer RJ, Decaprio JA, Srivastava S, Hanash SM, Hruban RH, Pandey A.

PLoS Med. 2009 Apr 7;6(4):e1000046. doi: 10.1371/journal.pmed.1000046. Epub 2009 Apr 7. Review. No abstract available.

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