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Items: 1 to 50 of 159

1.

Loss of a Negative Regulator of mTORC1 Induces Aerobic Glycolysis and Altered Fiber Composition in Skeletal Muscle.

Dutchak PA, Estill-Terpack SJ, Plec AA, Zhao X, Yang C, Chen J, Ko B, Deberardinis RJ, Yu Y, Tu BP.

Cell Rep. 2018 May 15;23(7):1907-1914. doi: 10.1016/j.celrep.2018.04.058.

2.

Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis.

Ryu KW, Nandu T, Kim J, Challa S, DeBerardinis RJ, Kraus WL.

Science. 2018 May 11;360(6389). pii: eaan5780. doi: 10.1126/science.aan5780.

PMID:
29748257
3.

Applications of metabolomics to study cancer metabolism.

Kaushik AK, DeBerardinis RJ.

Biochim Biophys Acta. 2018 Apr 25. pii: S0304-419X(18)30050-7. doi: 10.1016/j.bbcan.2018.04.009. [Epub ahead of print] Review.

PMID:
29702206
4.

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.

McMillan EA, Ryu MJ, Diep CH, Mendiratta S, Clemenceau JR, Vaden RM, Kim JH, Motoyaji T, Covington KR, Peyton M, Huffman K, Wu X, Girard L, Sung Y, Chen PH, Mallipeddi PL, Lee JY, Hanson J, Voruganti S, Yu Y, Park S, Sudderth J, DeSevo C, Muzny DM, Doddapaneni H, Gazdar A, Gibbs RA, Hwang TH, Heymach JV, Wistuba I, Coombes KR, Williams NS, Wheeler DA, MacMillan JB, Deberardinis RJ, Roth MG, Posner BA, Minna JD, Kim HS, White MA.

Cell. 2018 May 3;173(4):864-878.e29. doi: 10.1016/j.cell.2018.03.028. Epub 2018 Apr 19.

PMID:
29681454
5.

Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis.

Zhang Z, Zi Z, Lee EE, Zhao J, Contreras DC, South AP, Abel ED, Chong BF, Vandergriff T, Hosler GA, Scherer PE, Mettlen M, Rathmell JC, DeBerardinis RJ, Wang RC.

Nat Med. 2018 May;24(5):617-627. doi: 10.1038/s41591-018-0003-0. Epub 2018 Apr 16.

PMID:
29662201
6.

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

Flowers EM, Sudderth J, Zacharias L, Mernaugh G, Zent R, DeBerardinis RJ, Carroll TJ.

Nat Commun. 2018 Feb 26;9(1):814. doi: 10.1038/s41467-018-03036-y.

7.

RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells.

Hawk MA, Gorsuch CL, Fagan P, Lee C, Kim SE, Hamann JC, Mason JA, Weigel KJ, Tsegaye MA, Shen L, Shuff S, Zuo J, Hu S, Jiang L, Chapman S, Leevy WM, DeBerardinis RJ, Overholtzer M, Schafer ZT.

Nat Cell Biol. 2018 Mar;20(3):272-284. doi: 10.1038/s41556-018-0034-2. Epub 2018 Feb 19.

PMID:
29459781
8.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

9.

Genomic regression analysis of coordinated expression.

Cai L, Li Q, Du Y, Yun J, Xie Y, DeBerardinis RJ, Xiao G.

Nat Commun. 2017 Dec 19;8(1):2187. doi: 10.1038/s41467-017-02181-0.

10.

Lipoic acid metabolism and mitochondrial redox regulation.

Solmonson A, DeBerardinis RJ.

J Biol Chem. 2018 May 18;293(20):7522-7530. doi: 10.1074/jbc.TM117.000259. Epub 2017 Nov 30. Review.

PMID:
29191830
11.

The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts.

Shi X, Tasdogan A, Huang F, Hu Z, Morrison SJ, DeBerardinis RJ.

Sci Adv. 2017 Nov 1;3(11):eaao5268. doi: 10.1126/sciadv.aao5268. eCollection 2017 Nov.

12.

Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications.

Fischer GM, Vashisht Gopal YN, McQuade JL, Peng W, DeBerardinis RJ, Davies MA.

Pigment Cell Melanoma Res. 2018 Jan;31(1):11-30. doi: 10.1111/pcmr.12661. Epub 2017 Nov 2. Review.

PMID:
29049843
13.

Lactate Metabolism in Human Lung Tumors.

Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ.

Cell. 2017 Oct 5;171(2):358-371.e9. doi: 10.1016/j.cell.2017.09.019.

PMID:
28985563
14.

Engineering approaches to study cancer metabolism.

Metallo CM, Deberardinis RJ.

Metab Eng. 2017 Sep;43(Pt B):93. doi: 10.1016/j.ymben.2017.09.002. No abstract available.

PMID:
28918847
15.

The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.

Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME.

J Biol Chem. 2017 Nov 3;292(44):18203-18216. doi: 10.1074/jbc.M117.813923. Epub 2017 Sep 15.

PMID:
28916726
16.

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.

Agathocleous M, Meacham CE, Burgess RJ, Piskounova E, Zhao Z, Crane GM, Cowin BL, Bruner E, Murphy MM, Chen W, Spangrude GJ, Hu Z, DeBerardinis RJ, Morrison SJ.

Nature. 2017 Sep 28;549(7673):476-481. doi: 10.1038/nature23876. Epub 2017 Aug 21.

17.

Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.

Schell JC, Wisidagama DR, Bensard C, Zhao H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, Olson KA, Miao R, Waller TC, Delker D, Kanth P, Jiang L, DeBerardinis RJ, Bronner MP, Li DY, Cox JE, Christofk HR, Lowry WE, Thummel CS, Rutter J.

Nat Cell Biol. 2017 Sep;19(9):1027-1036. doi: 10.1038/ncb3593. Epub 2017 Aug 14.

PMID:
28812582
18.

Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI.

Zhang Y, Udayakumar D, Cai L, Hu Z, Kapur P, Kho EY, Pavía-Jiménez A, Fulkerson M, de Leon AD, Yuan Q, Dimitrov IE, Yokoo T, Ye J, Mitsche MA, Kim H, McDonald JG, Xi Y, Madhuranthakam AJ, Dwivedi DK, Lenkinski RE, Cadeddu JA, Margulis V, Brugarolas J, DeBerardinis RJ, Pedrosa I.

JCI Insight. 2017 Aug 3;2(15). pii: 94278. doi: 10.1172/jci.insight.94278. [Epub ahead of print]

19.

Cytochrome c Oxidase Activity Is a Metabolic Checkpoint that Regulates Cell Fate Decisions During T Cell Activation and Differentiation.

Tarasenko TN, Pacheco SE, Koenig MK, Gomez-Rodriguez J, Kapnick SM, Diaz F, Zerfas PM, Barca E, Sudderth J, DeBerardinis RJ, Covian R, Balaban RS, DiMauro S, McGuire PJ.

Cell Metab. 2017 Jun 6;25(6):1254-1268.e7. doi: 10.1016/j.cmet.2017.05.007.

20.

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ.

Nature. 2017 Jun 1;546(7656):168-172. doi: 10.1038/nature22359. Epub 2017 May 24.

21.

Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation.

Liu X, Zhang Y, Ni M, Cao H, Signer RAJ, Li D, Li M, Gu Z, Hu Z, Dickerson KE, Weinberg SE, Chandel NS, DeBerardinis RJ, Zhou F, Shao Z, Xu J.

Nat Cell Biol. 2017 Jun;19(6):626-638. doi: 10.1038/ncb3527. Epub 2017 May 15.

22.

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.

Eskiocak B, McMillan EA, Mendiratta S, Kollipara RK, Zhang H, Humphries CG, Wang C, Garcia-Rodriguez J, Ding M, Zaman A, Rosales TI, Eskiocak U, Smith MP, Sudderth J, Komurov K, Deberardinis RJ, Wellbrock C, Davies MA, Wargo JA, Yu Y, De Brabander JK, Williams NS, Chin L, Rizos H, Long GV, Kittler R, White MA.

Cancer Discov. 2017 Aug;7(8):832-851. doi: 10.1158/2159-8290.CD-16-0955. Epub 2017 Apr 28.

PMID:
28455392
23.

Using a novel NQO1 bioactivatable drug, beta-lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer.

Beg MS, Huang X, Silvers MA, Gerber DE, Bolluyt J, Sarode V, Fattah F, Deberardinis RJ, Merritt ME, Xie XJ, Leff R, Laheru D, Boothman DA.

J Surg Oncol. 2017 Jul;116(1):83-88. doi: 10.1002/jso.24624. Epub 2017 Mar 27.

PMID:
28346693
24.

Understanding the Intersections between Metabolism and Cancer Biology.

Vander Heiden MG, DeBerardinis RJ.

Cell. 2017 Feb 9;168(4):657-669. doi: 10.1016/j.cell.2016.12.039. Review.

25.

Oxidation of [U-13 C]glucose in the human brain at 7T under steady state conditions.

Cheshkov S, Dimitrov IE, Jakkamsetti V, Good L, Kelly D, Rajasekaran K, DeBerardinis RJ, Pascual JM, Sherry AD, Malloy CR.

Magn Reson Med. 2017 Dec;78(6):2065-2071. doi: 10.1002/mrm.26603. Epub 2017 Jan 23.

PMID:
28112825
26.

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.

Hasan M, Gonugunta VK, Dobbs N, Ali A, Palchik G, Calvaruso MA, DeBerardinis RJ, Yan N.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):746-751. doi: 10.1073/pnas.1611113114. Epub 2017 Jan 9.

27.

Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.

Fan J, Lin R, Xia S, Chen D, Elf SE, Liu S, Pan Y, Xu H, Qian Z, Wang M, Shan C, Zhou L, Lei QY, Li Y, Mao H, Lee BH, Sudderth J, DeBerardinis RJ, Zhang G, Owonikoko T, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Kang S, Doetsch PW, Lonial S, Boggon TJ, Curran WJ, Chen J.

Mol Cell. 2016 Dec 1;64(5):859-874. doi: 10.1016/j.molcel.2016.10.014. Epub 2016 Nov 17.

28.

Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein.

Jiang L, Boufersaoui A, Yang C, Ko B, Rakheja D, Guevara G, Hu Z, DeBerardinis RJ.

Metab Eng. 2017 Sep;43(Pt B):198-207. doi: 10.1016/j.ymben.2016.11.004. Epub 2016 Nov 14.

PMID:
27856334
29.

Hypoxia induces heart regeneration in adult mice.

Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA.

Nature. 2017 Jan 12;541(7636):222-227. doi: 10.1038/nature20173. Epub 2016 Oct 31.

PMID:
27798600
30.

Glutathione Depletion, Pentose Phosphate Pathway Activation, and Hemolysis in Erythrocytes Protecting Cancer Cells from Vitamin C-induced Oxidative Stress.

Zhang ZZ, Lee EE, Sudderth J, Yue Y, Zia A, Glass D, Deberardinis RJ, Wang RC.

J Biol Chem. 2016 Oct 28;291(44):22861-22867. Epub 2016 Sep 22.

31.

Blocking fatty acid synthesis reduces lung tumor growth in mice.

Kim J, DeBerardinis RJ.

Nat Med. 2016 Oct 6;22(10):1077-1078. doi: 10.1038/nm.4195. No abstract available.

PMID:
27711061
32.

AACR Cancer Progress Report 2016.

Davidson NE, Armstrong SA, Coussens LM, Cruz-Correa MR, DeBerardinis RJ, Doroshow JH, Foti M, Hwu P, Kensler TW, Morrow M, Mulligan CG, Pao W, Platz EA, Smith TJ, Willman CL.

Clin Cancer Res. 2016 Oct 1;22(19 Supplement):S1-S137. No abstract available.

33.

Erratum: Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma.

Eskiocak U, Ramesh V, Gill JG, Zhao Z, Yuan SW, Wang M, Vandergriff T, Shackleton M, Quintana E, Frankel AE, Johnson TM, DeBerardinis RJ, Morrison SJ.

Nat Commun. 2016 Sep 29;7:13080. doi: 10.1038/ncomms13080. No abstract available.

34.

Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine.

Cetinbas NM, Sudderth J, Harris RC, Cebeci A, Negri GL, Yılmaz ÖH, DeBerardinis RJ, Sorensen PH.

Sci Rep. 2016 Sep 8;6:32606. doi: 10.1038/srep32606.

35.

Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features.

Ouyang Q, Nakayama T, Baytas O, Davidson SM, Yang C, Schmidt M, Lizarraga SB, Mishra S, Ei-Quessny M, Niaz S, Gul Butt M, Imran Murtaza S, Javed A, Chaudhry HR, Vaughan DJ, Hill RS, Partlow JN, Yoo SY, Lam AT, Nasir R, Al-Saffar M, Barkovich AJ, Schwede M, Nagpal S, Rajab A, DeBerardinis RJ, Housman DE, Mochida GH, Morrow EM.

Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5598-607. doi: 10.1073/pnas.1609221113. Epub 2016 Sep 6.

36.

Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities.

Goveia J, Pircher A, Conradi LC, Kalucka J, Lagani V, Dewerchin M, Eelen G, DeBerardinis RJ, Wilson ID, Carmeliet P.

EMBO Mol Med. 2016 Oct 4;8(10):1134-1142. doi: 10.15252/emmm.201606798. Print 2016 Oct.

37.

Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma.

Eskiocak U, Ramesh V, Gill JG, Zhao Z, Yuan SW, Wang M, Vandergriff T, Shackleton M, Quintana E, Johnson TM, DeBerardinis RJ, Morrison SJ.

Nat Commun. 2016 Aug 22;7:12336. doi: 10.1038/ncomms12336.

38.

Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.

Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, Yang C, Batten K, Huffman KE, Liu J, Tang X, Rodriguez-Canales J, Kalhor N, Shay JW, Minna JD, McDonald J, Wistuba II, DeBerardinis RJ, Scaglioni PP.

Cell Rep. 2016 Aug 9;16(6):1614-1628. doi: 10.1016/j.celrep.2016.07.009. Epub 2016 Jul 28.

39.

Fundamentals of cancer metabolism.

DeBerardinis RJ, Chandel NS.

Sci Adv. 2016 May 27;2(5):e1600200. doi: 10.1126/sciadv.1600200. eCollection 2016 May. Review.

40.

Proliferating Cells Conserve Nitrogen to Support Growth.

DeBerardinis RJ.

Cell Metab. 2016 Jun 14;23(6):957-958. doi: 10.1016/j.cmet.2016.05.008.

41.

From "N of 1" to N of more.

DeBerardinis RJ, Mardis ER.

Cold Spring Harb Mol Case Stud. 2015 Oct;1(1):a000521. doi: 10.1101/mcs.a000521. No abstract available.

42.

Liposuction: Extracellular Fat Removal Promotes Proliferation.

Egnatchik RA, DeBerardinis RJ.

Cell Chem Biol. 2016 Apr 21;23(4):431-2. doi: 10.1016/j.chembiol.2016.04.003.

43.

Reductive carboxylation supports redox homeostasis during anchorage-independent growth.

Jiang L, Shestov AA, Swain P, Yang C, Parker SJ, Wang QA, Terada LS, Adams ND, McCabe MT, Pietrak B, Schmidt S, Metallo CM, Dranka BP, Schwartz B, DeBerardinis RJ.

Nature. 2016 Apr 14;532(7598):255-8. doi: 10.1038/nature17393. Epub 2016 Apr 6.

44.

Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer.

DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC.

Nat Genet. 2016 Apr;48(4):473. doi: 10.1038/ng0329-473a. No abstract available.

PMID:
27023779
45.

Hepatic gluconeogenesis influences (13)C enrichment in lactate in human brain tumors during metabolism of [1,2-(13)C]acetate.

Pichumani K, Mashimo T, Vemireddy V, Kovacs Z, Ratnakar J, Mickey B, Malloy CR, DeBerardinis RJ, Bachoo RM, Maher EA.

Neurochem Int. 2016 Jul;97:133-6. doi: 10.1016/j.neuint.2016.03.015. Epub 2016 Mar 26.

46.

Metabolic Heterogeneity in Human Lung Tumors.

Hensley CT, Faubert B, Yuan Q, Lev-Cohain N, Jin E, Kim J, Jiang L, Ko B, Skelton R, Loudat L, Wodzak M, Klimko C, McMillan E, Butt Y, Ni M, Oliver D, Torrealba J, Malloy CR, Kernstine K, Lenkinski RE, DeBerardinis RJ.

Cell. 2016 Feb 11;164(4):681-94. doi: 10.1016/j.cell.2015.12.034. Epub 2016 Feb 4.

47.

Cutting Edge: Critical Role of Glycolysis in Human Plasmacytoid Dendritic Cell Antiviral Responses.

Bajwa G, DeBerardinis RJ, Shao B, Hall B, Farrar JD, Gill MA.

J Immunol. 2016 Mar 1;196(5):2004-9. doi: 10.4049/jimmunol.1501557. Epub 2016 Jan 29.

48.

TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions.

Martínez-Reyes I, Diebold LP, Kong H, Schieber M, Huang H, Hensley CT, Mehta MM, Wang T, Santos JH, Woychik R, Dufour E, Spelbrink JN, Weinberg SE, Zhao Y, DeBerardinis RJ, Chandel NS.

Mol Cell. 2016 Jan 21;61(2):199-209. doi: 10.1016/j.molcel.2015.12.002. Epub 2015 Dec 24.

49.

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis.

Griss T, Vincent EE, Egnatchik R, Chen J, Ma EH, Faubert B, Viollet B, DeBerardinis RJ, Jones RG.

PLoS Biol. 2015 Dec 1;13(12):e1002309. doi: 10.1371/journal.pbio.1002309. eCollection 2015 Dec.

50.

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.

Chakrabarti G, Silvers MA, Ilcheva M, Liu Y, Moore ZR, Luo X, Gao J, Anderson G, Liu L, Sarode V, Gerber DE, Burma S, DeBerardinis RJ, Gerson SL, Boothman DA.

Sci Rep. 2015 Nov 25;5:17066. doi: 10.1038/srep17066.

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