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Items: 31

1.

CSF-1 controls cerebellar microglia and is required for motor function and social interaction.

Kana V, Desland FA, Casanova-Acebes M, Ayata P, Badimon A, Nabel E, Yamamuro K, Sneeboer M, Tan IL, Flanigan ME, Rose SA, Chang C, Leader A, Le Bourhis H, Sweet ES, Tung N, Wroblewska A, Lavin Y, See P, Baccarini A, Ginhoux F, Chitu V, Stanley ER, Russo SJ, Yue Z, Brown BD, Joyner AL, De Witte LD, Morishita H, Schaefer A, Merad M.

J Exp Med. 2019 Jul 26. pii: jem.20182037. doi: 10.1084/jem.20182037. [Epub ahead of print]

PMID:
31350310
2.

Vitamin D concentration and psychotic disorder: associations with disease status, clinical variables and urbanicity.

van der Leeuw C, de Witte LD, Stellinga A, van der Ley C, Bruggeman R, Kahn RS, van Os J, Marcelis M; for G.R.O.U.P.

Psychol Med. 2019 Jul 22:1-7. doi: 10.1017/S0033291719001739. [Epub ahead of print]

PMID:
31327333
3.

B-cells and schizophrenia: A promising link or a finding lost in translation?

van Mierlo HC, Broen JCA, Kahn RS, de Witte LD.

Brain Behav Immun. 2019 Jul 2. pii: S0889-1591(19)30484-2. doi: 10.1016/j.bbi.2019.06.043. [Epub ahead of print] Review.

PMID:
31271869
4.

Synapse Pathology in Schizophrenia: A Meta-analysis of Postsynaptic Elements in Postmortem Brain Studies.

Berdenis van Berlekom A, Muflihah CH, Snijders GJLJ, MacGillavry HD, Middeldorp J, Hol EM, Kahn RS, de Witte LD.

Schizophr Bull. 2019 Jun 13. pii: sbz060. doi: 10.1093/schbul/sbz060. [Epub ahead of print]

PMID:
31192350
5.

Neurons and glial cells in bipolar disorder: A systematic review of postmortem brain studies of cell number and size.

Gigase FAJ, Snijders GJLJ, Boks MP, de Witte LD.

Neurosci Biobehav Rev. 2019 Aug;103:150-162. doi: 10.1016/j.neubiorev.2019.05.027. Epub 2019 Jun 1. Review.

PMID:
31163205
6.

The association between schizophrenia and the immune system: Review of the evidence from unbiased 'omic-studies'.

van Mierlo HC, Schot A, Boks MPM, de Witte LD.

Schizophr Res. 2019 May 23. pii: S0920-9964(19)30204-X. doi: 10.1016/j.schres.2019.05.028. [Epub ahead of print]

PMID:
31130400
7.

Microglia in post-mortem brain tissue of patients with bipolar disorder are not immune activated.

Sneeboer MAM, Snijders GJLJ, Berdowski WM, Fernández-Andreu A; Psychiatric Donor Program of the Netherlands Brain Bank (NBB-Psy), van Mierlo HC, Berdenis van Berlekom A, Litjens M, Kahn RS, Hol EM, de Witte LD.

Transl Psychiatry. 2019 May 24;9(1):153. doi: 10.1038/s41398-019-0490-x.

8.

DNA methylation changes related to nutritional deprivation: a genome-wide analysis of population and in vitro data.

He Y, de Witte LD, Houtepen LC, Nispeling DM, Xu Z, Yu Q, Yu Y, Hol EM, Kahn RS, Boks MP.

Clin Epigenetics. 2019 May 16;11(1):80. doi: 10.1186/s13148-019-0680-7.

9.

Liprin alfa 2 gene expression is increased by cannabis use and associated with neuropsychological function.

He Y, de Witte LD, Schubart CD, Van Gastel WA, Koeleman BPC, de Jong S, Ophoff RA, Hol EM, Boks MP.

Eur Neuropsychopharmacol. 2019 May;29(5):643-652. doi: 10.1016/j.euroneuro.2019.03.004. Epub 2019 Mar 15.

PMID:
30879928
10.

Childhood Adversity Is Associated With Increased KITLG Methylation in Healthy Individuals but Not in Bipolar Disorder Patients.

He Y, Vinkers CH, Houtepen LC, de Witte LD, Boks MP.

Front Psychiatry. 2019 Jan 22;9:743. doi: 10.3389/fpsyt.2018.00743. eCollection 2018.

11.

Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry.

Böttcher C, Schlickeiser S, Sneeboer MAM, Kunkel D, Knop A, Paza E, Fidzinski P, Kraus L, Snijders GJL, Kahn RS, Schulz AR, Mei HE; NBB-Psy, Hol EM, Siegmund B, Glauben R, Spruth EJ, de Witte LD, Priller J.

Nat Neurosci. 2019 Jan;22(1):78-90. doi: 10.1038/s41593-018-0290-2. Epub 2018 Dec 17.

PMID:
30559476
12.

Microglia innately develop within cerebral organoids.

Ormel PR, Vieira de Sá R, van Bodegraven EJ, Karst H, Harschnitz O, Sneeboer MAM, Johansen LE, van Dijk RE, Scheefhals N, Berdenis van Berlekom A, Ribes Martínez E, Kling S, MacGillavry HD, van den Berg LH, Kahn RS, Hol EM, de Witte LD, Pasterkamp RJ.

Nat Commun. 2018 Oct 9;9(1):4167. doi: 10.1038/s41467-018-06684-2.

13.

Genetic vulnerability to DUSP22 promoter hypermethylation is involved in the relation between in utero famine exposure and schizophrenia.

Boks MP, Houtepen LC, Xu Z, He Y, Ursini G, Maihofer AX, Rajarajan P, Yu Q, Xu H, Wu Y, Wang S, Shi JP, Hulshoff Pol HE, Strengman E, Rutten BPF, Jaffe AE, Kleinman JE, Baker DG, Hol EM, Akbarian S, Nievergelt CM, De Witte LD, Vinkers CH, Weinberger DR, Yu J, Kahn RS.

NPJ Schizophr. 2018 Aug 21;4(1):16. doi: 10.1038/s41537-018-0058-4.

14.

Virus discovery analyses on post-mortem brain tissue and cerebrospinal fluid of schizophrenia patients.

Tomasik J, Smits SL, Leweke FM, Eljasz P, Pas S, Kahn RS, Osterhaus ADME, Bahn S, de Witte LD.

Schizophr Res. 2018 Jul;197:605-606. doi: 10.1016/j.schres.2018.02.012. Epub 2018 Feb 23. No abstract available.

PMID:
29478863
15.

Are infectious agents involved in the pathogenesis of postpartum psychosis?

de Witte LD, Snijders G, Litjens M, Kamperman AM, Kushner SA, Kahn RS, Bergink V.

J Affect Disord. 2018 Mar 15;229:141-144. doi: 10.1016/j.jad.2017.12.069. Epub 2018 Jan 3.

PMID:
29310062
16.

Characterization of macrophages from schizophrenia patients.

Ormel PR, van Mierlo HC, Litjens M, Strien MEV, Hol EM, Kahn RS, de Witte LD.

NPJ Schizophr. 2017 Nov 14;3(1):41. doi: 10.1038/s41537-017-0042-4.

17.

No neuronal autoantibodies detected in plasma of patients with a bipolar I disorder.

Snijders G, Titulaer MJ, Bergink V, Bastiaansen AE, Schreurs MWJ, Ophoff RA, Boks MP, Kahn RS, de Witte LD.

Psychiatry Res. 2018 Jan;259:460-462. doi: 10.1016/j.psychres.2017.10.043. Epub 2017 Nov 2.

PMID:
29136601
18.

Telomere quantification in frontal and temporal brain tissue of patients with schizophrenia.

van Mierlo HC, Wichers CGK, He Y, Sneeboer MAM, Radstake TRDJ, Kahn RS, Broen JCA, de Witte LD.

J Psychiatr Res. 2017 Dec;95:231-234. doi: 10.1016/j.jpsychires.2017.09.006. Epub 2017 Sep 7.

PMID:
28910708
19.

Immune involvement in the pathogenesis of schizophrenia: a meta-analysis on postmortem brain studies.

van Kesteren CF, Gremmels H, de Witte LD, Hol EM, Van Gool AR, Falkai PG, Kahn RS, Sommer IE.

Transl Psychiatry. 2017 Mar 28;7(3):e1075. doi: 10.1038/tp.2017.4.

20.

Clinical consequences of extensive routine laboratory investigations in patients with a recent onset psychotic disorder.

van Mierlo HC, de Jel DVC, Palmen SJMC, van Veelen NM, Vinkers CH, de Witte LD.

Schizophr Res. 2017 Nov;189:210-212. doi: 10.1016/j.schres.2017.01.052. Epub 2017 Feb 3. No abstract available.

PMID:
28162811
21.

In vivo (R)-[(11)C]PK11195 PET imaging of 18kDa translocator protein in recent onset psychosis.

van der Doef TF, de Witte LD, Sutterland AL, Jobse E, Yaqub M, Boellaard R, de Haan L, Eriksson J, Lammertsma AA, Kahn RS, van Berckel BN.

NPJ Schizophr. 2016 Aug 31;2:16031. doi: 10.1038/npjschz.2016.31. eCollection 2016.

22.

[Aggression and restlessness following baclofen overdose: the narrow line between intoxication and withdrawal symptoms].

de Witte LD, Dekker D, Veraart J, Kromkamp M, Kaasjager K, Vinkers CH.

Ned Tijdschr Geneeskd. 2016;160:A9604. Dutch.

PMID:
27484417
23.

Characterizing primary human microglia: A comparative study with myeloid subsets and culture models.

Melief J, Sneeboer MA, Litjens M, Ormel PR, Palmen SJ, Huitinga I, Kahn RS, Hol EM, de Witte LD.

Glia. 2016 Nov;64(11):1857-68. doi: 10.1002/glia.23023. Epub 2016 Jul 21.

PMID:
27442614
24.

[Cushing's syndrome in a manic patient with a long-standing bipolar disorder: cause or coincidence?].

de Witte LD, Smits RB, Bartel M, Kleijweg M, Valk GD, Vinkers CH, Vergeer M.

Tijdschr Psychiatr. 2015;57(10):757-61. Dutch.

25.

Early recognition of anti-N-methyl-D-aspartate receptor encephalitis in psychiatric patients.

van Mierlo HC, Titulaer MJ, Kromkamp M, van de Kraats R, van Veelen NM, Palmen SJ, Kahn RS, de Witte LD.

Acta Psychiatr Scand. 2015 Oct;132(4):312-3. doi: 10.1111/acps.12471. No abstract available.

PMID:
26371800
26.

Absence of N-Methyl-D-Aspartate Receptor IgG Autoantibodies in Schizophrenia: The Importance of Cross-Validation Studies.

de Witte LD, Hoffmann C, van Mierlo HC, Titulaer MJ, Kahn RS, Martinez-Martinez P; European Consortium of Autoimmune Mental Disorders (CAIMED).

JAMA Psychiatry. 2015 Jul;72(7):731-3. doi: 10.1001/jamapsychiatry.2015.0526. No abstract available.

PMID:
25970159
27.

[Auto-immune disorders as a possible cause of neuropsychiatric syndromes].

Martinez-Martinez P, Molenaar PC, Losen M, Hoffmann C, Stevens J, de Witte LD, van Amelsvoort T, van Os J, Rutten BP.

Tijdschr Psychiatr. 2015;57(3):183-91. Review. Dutch.

28.

Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.

de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML.

Int J Cancer. 2015 Oct 1;137(7):1630-42. doi: 10.1002/ijc.29521. Epub 2015 Apr 7.

29.

The association between antibodies to neurotropic pathogens and schizophrenia: a case-control study.

de Witte LD, van Mierlo HC, Litjens M, Klein HC, Bahn S, Osterhaus AD; GROUP Investigators.

NPJ Schizophr. 2015 Nov 4;1:15041. doi: 10.1038/npjschz.2015.41. eCollection 2015.

30.

Genetic liability for schizophrenia predicts risk of immune disorders.

Stringer S, Kahn RS, de Witte LD, Ophoff RA, Derks EM.

Schizophr Res. 2014 Nov;159(2-3):347-52. doi: 10.1016/j.schres.2014.09.004. Epub 2014 Sep 26. Review.

31.

Efficacy of anti-inflammatory agents to improve symptoms in patients with schizophrenia: an update.

Sommer IE, van Westrhenen R, Begemann MJ, de Witte LD, Leucht S, Kahn RS.

Schizophr Bull. 2014 Jan;40(1):181-91. doi: 10.1093/schbul/sbt139. Epub 2013 Oct 8.

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