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Low Methoxyl Pectin Protects against Autoimmune Diabetes and Associated Caecal Dysfunction.

Wu C, Pan LL, Luo Y, Niu W, Fang X, Liang W, Li J, Li H, Pan X, Yang G, Chen W, Zhang H, Lakey JRT, Agerberth B, de Vos P, Sun J.

Mol Nutr Food Res. 2019 Aug 18:e1900307. doi: 10.1002/mnfr.201900307. [Epub ahead of print]


Modulation of Gut Microbiota by Low Methoxyl Pectin Attenuates Type 1 Diabetes in Non-obese Diabetic Mice.

Wu C, Pan LL, Niu W, Fang X, Liang W, Li J, Li H, Pan X, Chen W, Zhang H, Lakey JRT, Agerberth B, de Vos P, Sun J.

Front Immunol. 2019 Jul 30;10:1733. doi: 10.3389/fimmu.2019.01733. eCollection 2019.


Effect of oat and soybean rich in distinct non-starch polysaccharides on fermentation, appetite regulation and fat accumulation in rat.

Tian L, Scholte J, Scheurink AJW, van den Berg M, Bruggeman G, Bruininx E, de Vos P, Schols HA, Gruppen H.

Int J Biol Macromol. 2019 Aug 5;140:515-521. doi: 10.1016/j.ijbiomac.2019.08.032. [Epub ahead of print]


The Impact of Pectin Supplementation on Intestinal Barrier Function in Healthy Young Adults and Healthy Elderly.

Wilms E, Jonkers DMAE, Savelkoul HFJ, Elizalde M, Tischmann L, de Vos P, Masclee AAM, Troost FJ.

Nutrients. 2019 Jul 9;11(7). pii: E1554. doi: 10.3390/nu11071554.


Polymeric Approaches to Reduce Tissue Responses Against Devices Applied for Islet-Cell Encapsulation.

Hu S, de Vos P.

Front Bioeng Biotechnol. 2019 Jun 4;7:134. doi: 10.3389/fbioe.2019.00134. eCollection 2019. Review.


Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates.

Sremac M, Lei J, Penson MFE, Schuetz C, Lakey JRT, Papas KK, Varde PS, Hering B, de Vos P, Brauns T, Markmann J, Poznansky MC.

Transplant Direct. 2019 Apr 15;5(5):e447. doi: 10.1097/TXD.0000000000000890. eCollection 2019 May. Erratum in: Transplant Direct. 2019 Jun 21;5(7):e471.


Modulation of Intestinal Epithelial Glycocalyx Development by Human Milk Oligosaccharides and Non-Digestible Carbohydrates.

Kong C, Elderman M, Cheng L, de Haan BJ, Nauta A, de Vos P.

Mol Nutr Food Res. 2019 Sep;63(17):e1900303. doi: 10.1002/mnfr.201900303. Epub 2019 Jun 11.


Mathematical predictions of oxygen availability in micro- and macro-encapsulated human and porcine pancreatic islets.

Cao R, Avgoustiniatos E, Papas K, de Vos P, Lakey JRT.

J Biomed Mater Res B Appl Biomater. 2019 Apr 23. doi: 10.1002/jbm.b.34393. [Epub ahead of print]


Fibroblasts Impact Goblet Cell Responses to Lactic Acid Bacteria After Exposure to Inflammatory Cytokines and Mucus Disruptors.

Ren C, Dokter-Fokkens J, Figueroa Lozano S, Zhang Q, de Haan BJ, Zhang H, Faas MM, de Vos P.

Mol Nutr Food Res. 2019 Jun;63(12):e1801427. doi: 10.1002/mnfr.201801427. Epub 2019 Apr 22.


Shaping the Infant Microbiome With Non-digestible Carbohydrates.

Verkhnyatskaya S, Ferrari M, de Vos P, Walvoort MTC.

Front Microbiol. 2019 Feb 25;10:343. doi: 10.3389/fmicb.2019.00343. eCollection 2019. Review.


Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high d-glucose conditions.

Sáez T, de Vos P, Kuipers J, Sobrevia L, Faas MM.

Immunobiology. 2019 Mar;224(2):325-333. doi: 10.1016/j.imbio.2019.02.004. Epub 2019 Feb 22.


The role of autoimmunity in women with type 1 diabetes and adverse pregnancy outcome: A missing link.

Groen B, Links TP, van den Berg PP, de Vos P, Faas MM.

Immunobiology. 2019 Mar;224(2):334-338. doi: 10.1016/j.imbio.2019.02.003. Epub 2019 Feb 15. Review.


Editorial: Immunomodulatory Functions of Nutritional Ingredients in Health and Disease.

Sun J, de Vos P.

Front Immunol. 2019 Jan 24;10:50. doi: 10.3389/fimmu.2019.00050. eCollection 2019. No abstract available.


Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity.

Sovran B, Hugenholtz F, Elderman M, Van Beek AA, Graversen K, Huijskes M, Boekschoten MV, Savelkoul HFJ, De Vos P, Dekker J, Wells JM.

Sci Rep. 2019 Feb 5;9(1):1437. doi: 10.1038/s41598-018-35228-3.


Assessment of hypertension management and control: a registry-based observational study in two municipalities in Cuba.

Londoño Agudelo E, Rodríguez Salvá A, Díaz Piñera A, García Roche R, De Vos P, Battaglioli T, Van der Stuyft P.

BMC Cardiovasc Disord. 2019 Jan 30;19(1):29. doi: 10.1186/s12872-019-1006-6.


Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota.

van Beek AA, Fransen F, Meijer B, de Vos P, Knol EF, Savelkoul HFJ.

Immun Ageing. 2018 Nov 29;15:32. doi: 10.1186/s12979-018-0135-6. eCollection 2018.


Higher Chain Length Distribution in Debranched Type-3 Resistant Starches (RS3) Increases TLR Signaling and Supports Dendritic Cell Cytokine Production.

Lépine AFP, de Hilster RHJ, Leemhuis H, Oudhuis L, Buwalda PL, de Vos P.

Mol Nutr Food Res. 2019 Jan;63(2):e1801007. doi: 10.1002/mnfr.201801007. Epub 2018 Nov 23.


Identification of a TLR2 Inhibiting Wheat Hydrolysate.

Kiewiet MBG, Dekkers R, van Gool MP, Ulfman LH, Groeneveld A, Faas MM, de Vos P.

Mol Nutr Food Res. 2018 Dec;62(23):e1800716. doi: 10.1002/mnfr.201800716. Epub 2018 Nov 2.


Cuba's Strategy Toward Universal Health.

De Vos P.

Int J Health Serv. 2019 Jan;49(1):186-192. doi: 10.1177/0020731418804406. Epub 2018 Oct 6.


Sex differences in lipid metabolism are affected by presence of the gut microbiota.

Baars A, Oosting A, Lohuis M, Koehorst M, El Aidy S, Hugenholtz F, Smidt H, Mischke M, Boekschoten MV, Verkade HJ, Garssen J, van der Beek EM, Knol J, de Vos P, van Bergenhenegouwen J, Fransen F.

Sci Rep. 2018 Sep 7;8(1):13426. doi: 10.1038/s41598-018-31695-w.


The epithelial barrier-protecting properties of a soy hydrolysate.

Kiewiet MBG, González Rodríguez MI, Dekkers R, Gros M, Ulfman LH, Groeneveld A, de Vos P, Faas MM.

Food Funct. 2018 Aug 15;9(8):4164-4172. doi: 10.1039/c8fo00913a.


Lactobacillus acidophilus Attenuates Salmonella-Induced Stress of Epithelial Cells by Modulating Tight-Junction Genes and Cytokine Responses.

Lépine AFP, de Wit N, Oosterink E, Wichers H, Mes J, de Vos P.

Front Microbiol. 2018 Jul 2;9:1439. doi: 10.3389/fmicb.2018.01439. eCollection 2018.


Immunomodulatory Protein Hydrolysates and Their Application.

Kiewiet MBG, Faas MM, de Vos P.

Nutrients. 2018 Jul 14;10(7). pii: E904. doi: 10.3390/nu10070904. Review.


Changes in intestinal gene expression and microbiota composition during late pregnancy are mouse strain dependent.

Elderman M, Hugenholtz F, Belzer C, Boekschoten M, de Haan B, de Vos P, Faas M.

Sci Rep. 2018 Jul 3;8(1):10001. doi: 10.1038/s41598-018-28292-2.


Sex and strain dependent differences in mucosal immunology and microbiota composition in mice.

Elderman M, Hugenholtz F, Belzer C, Boekschoten M, van Beek A, de Haan B, Savelkoul H, de Vos P, Faas M.

Biol Sex Differ. 2018 Jun 18;9(1):26. doi: 10.1186/s13293-018-0186-6.


Role of Microbiota in Sexually Dimorphic Immunity.

Elderman M, de Vos P, Faas M.

Front Immunol. 2018 May 22;9:1018. doi: 10.3389/fimmu.2018.01018. eCollection 2018. Review.


Fetoplacental endothelial exosomes modulate high d-glucose-induced endothelial dysfunction.

Sáez T, de Vos P, Kuipers J, Sobrevia L, Faas MM.

Placenta. 2018 Jun;66:26-35. doi: 10.1016/j.placenta.2018.04.010. Epub 2018 Apr 21.


Polymer scaffolds for pancreatic islet transplantation - Progress and challenges.

Smink AM, de Haan BJ, Lakey JRT, de Vos P.

Am J Transplant. 2018 Sep;18(9):2113-2119. doi: 10.1111/ajt.14942. Epub 2018 Jun 13. Review.


Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells.

Sambathkumar R, Akkerman R, Dastidar S, Roelandt P, Kumar M, Bajaj M, Mestre Rosa AR, Helsen N, Vanslembrouck V, Kalo E, Khurana S, Laureys J, Gysemans C, Faas MM, de Vos P, Verfaillie CM.

PLoS One. 2018 May 11;13(5):e0197046. doi: 10.1371/journal.pone.0197046. eCollection 2018.


Innate immune cells in the placental bed in healthy pregnancy and preeclampsia.

Faas MM, De Vos P.

Placenta. 2018 Sep;69:125-133. doi: 10.1016/j.placenta.2018.04.012. Epub 2018 Apr 25. Review.


Corrigendum: Inulin-Type Fructans Modulates Pancreatic-Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner.

He Y, Wu C, Li J, Li H, Sun Z, Zhang H, de Vos P, Pan LL, Sun J.

Front Immunol. 2018 Apr 18;9:812. doi: 10.3389/fimmu.2018.00812. eCollection 2018.


Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply.

Evron Y, Colton CK, Ludwig B, Weir GC, Zimermann B, Maimon S, Neufeld T, Shalev N, Goldman T, Leon A, Yavriyants K, Shabtay N, Rozenshtein T, Azarov D, DiIenno AR, Steffen A, de Vos P, Bornstein SR, Barkai U, Rotem A.

Sci Rep. 2018 Apr 25;8(1):6508. doi: 10.1038/s41598-018-23862-w.


Dietary Fiber Pectin Directly Blocks Toll-Like Receptor 2-1 and Prevents Doxorubicin-Induced Ileitis.

Sahasrabudhe NM, Beukema M, Tian L, Troost B, Scholte J, Bruininx E, Bruggeman G, van den Berg M, Scheurink A, Schols HA, Faas MM, de Vos P.

Front Immunol. 2018 Mar 1;9:383. doi: 10.3389/fimmu.2018.00383. eCollection 2018.


Collagen type VI interaction improves human islet survival in immunoisolating microcapsules for treatment of diabetes.

Llacua LA, Hoek A, de Haan BJ, de Vos P.

Islets. 2018 Mar 4;10(2):60-68. doi: 10.1080/19382014.2017.1420449. Epub 2018 Mar 9.


Increased fecal calprotectin levels in Crohn's disease correlate with elevated serum Th1- and Th17-associated cytokines.

Bourgonje AR, von Martels JZH, de Vos P, Faber KN, Dijkstra G.

PLoS One. 2018 Feb 21;13(2):e0193202. doi: 10.1371/journal.pone.0193202. eCollection 2018.


Engineering a Clinically Translatable Bioartificial Pancreas to Treat Type I Diabetes.

Orive G, Emerich D, Khademhosseini A, Matsumoto S, Hernández RM, Pedraz JL, Desai T, Calafiore R, de Vos P.

Trends Biotechnol. 2018 Apr;36(4):445-456. doi: 10.1016/j.tibtech.2018.01.007. Epub 2018 Feb 15. Review.


L. plantarum WCFS1 enhances Treg frequencies by activating DCs even in absence of sampling of bacteria in the Peyer Patches.

Bermudez-Brito M, Borghuis T, Daniel C, Pot B, de Haan BJ, Faas MM, de Vos P.

Sci Rep. 2018 Jan 29;8(1):1785. doi: 10.1038/s41598-018-20243-1.


Non-digestible carbohydrates in infant formula as substitution for human milk oligosaccharide functions: Effects on microbiota and gut maturation.

Akkerman R, Faas MM, de Vos P.

Crit Rev Food Sci Nutr. 2019;59(9):1486-1497. doi: 10.1080/10408398.2017.1414030. Epub 2018 Jan 15.


Lactic Acid Bacteria May Impact Intestinal Barrier Function by Modulating Goblet Cells.

Ren C, Dokter-Fokkens J, Figueroa Lozano S, Zhang Q, de Haan BJ, Zhang H, Faas MM, de Vos P.

Mol Nutr Food Res. 2018 Mar;62(6):e1700572. doi: 10.1002/mnfr.201700572. Epub 2018 Feb 26.


Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets.

Llacua LA, Faas MM, de Vos P.

Diabetologia. 2018 Jun;61(6):1261-1272. doi: 10.1007/s00125-017-4524-8. Epub 2018 Jan 6. Review.


Is there a role for exosomes in foetoplacental endothelial dysfunction in gestational diabetes mellitus?

Sáez T, de Vos P, Sobrevia L, Faas MM.

Placenta. 2018 Jan;61:48-54. doi: 10.1016/j.placenta.2017.11.007. Epub 2017 Nov 14. Review.


Recent progress in the use and tracking of transplanted islets as a personalized treatment for type 1 diabetes.

Paredes-Juarez GA, de Vos P, Bulte JWM.

Expert Rev Precis Med Drug Dev. 2017;2(1):57-67. doi: 10.1080/23808993.2017.1302305. Epub 2017 Mar 13.


Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice.

Fransen F, van Beek AA, Borghuis T, Aidy SE, Hugenholtz F, van der Gaast-de Jongh C, Savelkoul HFJ, De Jonge MI, Boekschoten MV, Smidt H, Faas MM, de Vos P.

Front Immunol. 2017 Nov 2;8:1385. doi: 10.3389/fimmu.2017.01385. eCollection 2017.


Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus.

Sáez T, Salsoso R, Leiva A, Toledo F, de Vos P, Faas M, Sobrevia L.

Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):499-508. doi: 10.1016/j.bbadis.2017.11.010. Epub 2017 Nov 15.


Unbiased random mutagenesis contributes to a better understanding of the virulent behaviour of Paenibacillus larvae.

Descamps T, De Smet L, De Vos P, de Graaf DC.

J Appl Microbiol. 2018 Jan;124(1):28-41. doi: 10.1111/jam.13611. Epub 2017 Dec 18.


Inulin-Type Fructans Modulates Pancreatic-Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner.

He Y, Wu C, Li J, Li H, Sun Z, Zhang H, de Vos P, Pan LL, Sun J.

Front Immunol. 2017 Sep 26;8:1209. doi: 10.3389/fimmu.2017.01209. eCollection 2017. Erratum in: Front Immunol. 2018 Apr 18;9:812.

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