Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38

1.

MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics.

Larrea D, Pera M, Gonelli A, Cabrera RQ, Akman HO, Guardia-Laguarta C, Velasco KR, Area-Gomez E, Dal Bello F, De Stefani D, Horvath R, Shy ME, Schon EA, Giacomello M.

Hum Mol Genet. 2019 Jan 11. doi: 10.1093/hmg/ddz008. [Epub ahead of print]

PMID:
30649465
2.

Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)-Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans.

Carnevale D, Facchinello N, Iodice D, Bizzotto D, Perrotta M, De Stefani D, Pallante F, Carnevale L, Ricciardi F, Cifelli G, Da Ros F, Casaburo M, Fardella S, Bonaldo P, Innocenzi G, Rizzuto R, Braghetta P, Lembo G, Bressan GM.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2484-2497. doi: 10.1161/ATVBAHA.118.311115.

PMID:
30354220
3.

Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference.

Gherardi G, Nogara L, Ciciliot S, Fadini GP, Blaauw B, Braghetta P, Bonaldo P, De Stefani D, Rizzuto R, Mammucari C.

Cell Death Differ. 2019 Jan;26(2):362-381. doi: 10.1038/s41418-018-0191-7. Epub 2018 Sep 19.

4.

Tau localises within mitochondrial sub-compartments and its caspase cleavage affects ER-mitochondria interactions and cellular Ca2+ handling.

Cieri D, Vicario M, Vallese F, D'Orsi B, Berto P, Grinzato A, Catoni C, De Stefani D, Rizzuto R, Brini M, Calì T.

Biochim Biophys Acta Mol Basis Dis. 2018 Oct;1864(10):3247-3256. doi: 10.1016/j.bbadis.2018.07.011. Epub 2018 Jul 11.

PMID:
30006151
5.

Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism.

Díaz-Vegas AR, Cordova A, Valladares D, Llanos P, Hidalgo C, Gherardi G, De Stefani D, Mammucari C, Rizzuto R, Contreras-Ferrat A, Jaimovich E.

Front Physiol. 2018 Jun 25;9:791. doi: 10.3389/fphys.2018.00791. eCollection 2018.

6.

MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake.

Patron M, Granatiero V, Espino J, Rizzuto R, De Stefani D.

Cell Death Differ. 2019 Jan;26(1):179-195. doi: 10.1038/s41418-018-0113-8. Epub 2018 May 3.

7.

LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux.

Austin S, Tavakoli M, Pfeiffer C, Seifert J, Mattarei A, De Stefani D, Zoratti M, Nowikovsky K.

Front Physiol. 2017 Nov 17;8:839. doi: 10.3389/fphys.2017.00839. eCollection 2017.

8.

Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy.

Zaglia T, Ceriotti P, Campo A, Borile G, Armani A, Carullo P, Prando V, Coppini R, Vida V, Stølen TO, Ulrik W, Cerbai E, Stellin G, Faggian G, De Stefani D, Sandri M, Rizzuto R, Di Lisa F, Pozzan T, Catalucci D, Mongillo M.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9006-E9015. doi: 10.1073/pnas.1708772114. Epub 2017 Oct 9.

9.

The MCU complex in cell death.

Penna E, Espino J, De Stefani D, Rizzuto R.

Cell Calcium. 2018 Jan;69:73-80. doi: 10.1016/j.ceca.2017.08.008. Epub 2017 Aug 25. Review.

PMID:
28867646
10.

Mitochondrial Calcium Handling in Physiology and Disease.

Granatiero V, De Stefani D, Rizzuto R.

Adv Exp Med Biol. 2017;982:25-47. doi: 10.1007/978-3-319-55330-6_2. Review.

PMID:
28551780
11.

Reply to Filadi et al.: Does Mitofusin 2 tether or separate endoplasmic reticulum and mitochondria?

Naon D, Zaninello M, Giacomello M, Varanita T, Grespi F, Lakshminaranayan S, Serafini A, Semenzato M, Herkenne S, Hernández-Alvarez MI, Zorzano A, De Stefani D, Dorn GW 2nd, Scorrano L.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2268-E2269. doi: 10.1073/pnas.1618610114. Epub 2017 Mar 13. No abstract available.

12.

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum-mitochondria tether.

Naon D, Zaninello M, Giacomello M, Varanita T, Grespi F, Lakshminaranayan S, Serafini A, Semenzato M, Herkenne S, Hernández-Alvarez MI, Zorzano A, De Stefani D, Dorn GW 2nd, Scorrano L.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11249-11254. Epub 2016 Sep 19.

13.

The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria.

König T, Tröder SE, Bakka K, Korwitz A, Richter-Dennerlein R, Lampe PA, Patron M, Mühlmeister M, Guerrero-Castillo S, Brandt U, Decker T, Lauria I, Paggio A, Rizzuto R, Rugarli EI, De Stefani D, Langer T.

Mol Cell. 2016 Oct 6;64(1):148-162. doi: 10.1016/j.molcel.2016.08.020. Epub 2016 Sep 15.

14.

Enjoy the Trip: Calcium in Mitochondria Back and Forth.

De Stefani D, Rizzuto R, Pozzan T.

Annu Rev Biochem. 2016 Jun 2;85:161-92. doi: 10.1146/annurev-biochem-060614-034216. Epub 2016 May 4. Review.

PMID:
27145841
15.

Reduced mitochondrial Ca(2+) transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase.

Granatiero V, Giorgio V, Calì T, Patron M, Brini M, Bernardi P, Tiranti V, Zeviani M, Pallafacchina G, De Stefani D, Rizzuto R.

Cell Death Differ. 2016 Feb;23(2):231-41. doi: 10.1038/cdd.2015.84. Epub 2015 Jul 24.

16.

Structure and function of the mitochondrial calcium uniporter complex.

De Stefani D, Patron M, Rizzuto R.

Biochim Biophys Acta. 2015 Sep;1853(9):2006-11. doi: 10.1016/j.bbamcr.2015.04.008. Epub 2015 Apr 18. Review.

17.

The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo.

Mammucari C, Gherardi G, Zamparo I, Raffaello A, Boncompagni S, Chemello F, Cagnin S, Braga A, Zanin S, Pallafacchina G, Zentilin L, Sandri M, De Stefani D, Protasi F, Lanfranchi G, Rizzuto R.

Cell Rep. 2015 Mar 3;10(8):1269-79. doi: 10.1016/j.celrep.2015.01.056. Epub 2015 Feb 26.

18.

Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB.

Medina DL, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, Montefusco S, Scotto-Rosato A, Prezioso C, Forrester A, Settembre C, Wang W, Gao Q, Xu H, Sandri M, Rizzuto R, De Matteis MA, Ballabio A.

Nat Cell Biol. 2015 Mar;17(3):288-99.

19.

Measuring baseline Ca(2+) levels in subcellular compartments using genetically engineered fluorescent indicators.

Hill JM, De Stefani D, Jones AW, Ruiz A, Rizzuto R, Szabadkai G.

Methods Enzymol. 2014;543:47-72. doi: 10.1016/B978-0-12-801329-8.00003-9.

PMID:
24924127
20.

Molecular control of mitochondrial calcium uptake.

De Stefani D, Rizzuto R.

Biochem Biophys Res Commun. 2014 Jul 11;449(4):373-6. doi: 10.1016/j.bbrc.2014.04.142. Epub 2014 Apr 30.

PMID:
24792182
21.

MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity.

Patron M, Checchetto V, Raffaello A, Teardo E, Vecellio Reane D, Mantoan M, Granatiero V, Szabò I, De Stefani D, Rizzuto R.

Mol Cell. 2014 Mar 6;53(5):726-37. doi: 10.1016/j.molcel.2014.01.013. Epub 2014 Feb 20.

22.

Human white adipocytes express the cold receptor TRPM8 which activation induces UCP1 expression, mitochondrial activation and heat production.

Rossato M, Granzotto M, Macchi V, Porzionato A, Petrelli L, Calcagno A, Vencato J, De Stefani D, Silvestrin V, Rizzuto R, Bassetto F, De Caro R, Vettor R.

Mol Cell Endocrinol. 2014 Mar 5;383(1-2):137-46. doi: 10.1016/j.mce.2013.12.005. Epub 2013 Dec 14.

PMID:
24342393
23.

Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling.

Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R; UK10K Consortium, Duchen MR, Muntoni F, Sheridan E.

Nat Genet. 2014 Feb;46(2):188-93. doi: 10.1038/ng.2851. Epub 2013 Dec 15.

PMID:
24336167
24.

The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.

Raffaello A, De Stefani D, Sabbadin D, Teardo E, Merli G, Picard A, Checchetto V, Moro S, Szabò I, Rizzuto R.

EMBO J. 2013 Aug 28;32(17):2362-76. doi: 10.1038/emboj.2013.157. Epub 2013 Jul 30.

25.

The mitochondrial calcium uniporter (MCU): molecular identity and physiological roles.

Patron M, Raffaello A, Granatiero V, Tosatto A, Merli G, De Stefani D, Wright L, Pallafacchina G, Terrin A, Mammucari C, Rizzuto R.

J Biol Chem. 2013 Apr 12;288(15):10750-8. doi: 10.1074/jbc.R112.420752. Epub 2013 Feb 11. Review.

26.

Mitochondria as sensors and regulators of calcium signalling.

Rizzuto R, De Stefani D, Raffaello A, Mammucari C.

Nat Rev Mol Cell Biol. 2012 Sep;13(9):566-78. doi: 10.1038/nrm3412. Epub 2012 Aug 1. Review.

PMID:
22850819
27.

Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes.

Drago I, De Stefani D, Rizzuto R, Pozzan T.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):12986-91. doi: 10.1073/pnas.1210718109. Epub 2012 Jul 20.

28.

Respiratory dysfunction by AFG3L2 deficiency causes decreased mitochondrial calcium uptake via organellar network fragmentation.

Maltecca F, De Stefani D, Cassina L, Consolato F, Wasilewski M, Scorrano L, Rizzuto R, Casari G.

Hum Mol Genet. 2012 Sep 1;21(17):3858-70. doi: 10.1093/hmg/dds214. Epub 2012 Jun 7.

29.

The mitochondrial Ca(2+) uniporter.

Raffaello A, De Stefani D, Rizzuto R.

Cell Calcium. 2012 Jul;52(1):16-21. doi: 10.1016/j.ceca.2012.04.006. Epub 2012 Jun 4. Review.

PMID:
22672876
30.

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria.

De Stefani D, Bononi A, Romagnoli A, Messina A, De Pinto V, Pinton P, Rizzuto R.

Cell Death Differ. 2012 Feb;19(2):267-73. doi: 10.1038/cdd.2011.92. Epub 2011 Jul 1.

31.

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.

De Stefani D, Raffaello A, Teardo E, Szabò I, Rizzuto R.

Nature. 2011 Jun 19;476(7360):336-40. doi: 10.1038/nature10230.

32.

Structural and functional link between the mitochondrial network and the endoplasmic reticulum.

Giorgi C, De Stefani D, Bononi A, Rizzuto R, Pinton P.

Int J Biochem Cell Biol. 2009 Oct;41(10):1817-27. doi: 10.1016/j.biocel.2009.04.010. Epub 2009 Apr 21. Review.

33.

Ca(2+) transfer from the ER to mitochondria: when, how and why.

Rizzuto R, Marchi S, Bonora M, Aguiari P, Bononi A, De Stefani D, Giorgi C, Leo S, Rimessi A, Siviero R, Zecchini E, Pinton P.

Biochim Biophys Acta. 2009 Nov;1787(11):1342-51. doi: 10.1016/j.bbabio.2009.03.015. Epub 2009 Mar 31. Review.

34.

Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization.

Vettor R, Granzotto M, De Stefani D, Trevellin E, Rossato M, Farina MG, Milan G, Pilon C, Nigro A, Federspil G, Vigneri R, Vitiello L, Rizzuto R, Baratta R, Frittitta L.

J Clin Endocrinol Metab. 2008 Sep;93(9):3541-50. doi: 10.1210/jc.2007-2680. Epub 2008 Jun 26.

PMID:
18583466
35.

Endoplasmic reticulum/mitochondria calcium cross-talk.

Romagnoli A, Aguiari P, De Stefani D, Leo S, Marchi S, Rimessi A, Zecchini E, Pinton P, Rizzuto R.

Novartis Found Symp. 2007;287:122-31; discussion 131-9. Review.

PMID:
18074635
36.

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

Szabadkai G, Bianchi K, Várnai P, De Stefani D, Wieckowski MR, Cavagna D, Nagy AI, Balla T, Rizzuto R.

J Cell Biol. 2006 Dec 18;175(6):901-11.

37.

Mitochondrial dynamics and Ca2+ signaling.

Szabadkai G, Simoni AM, Bianchi K, De Stefani D, Leo S, Wieckowski MR, Rizzuto R.

Biochim Biophys Acta. 2006 May-Jun;1763(5-6):442-9. Epub 2006 Apr 20. Review.

38.

[Gangliosides: a new prospective therapy of uremic neuropathy].

Bernardi A, Dainese R, Brazzo F, Caniato G, Uliari U, De Stefani D, Poluzzi P, Bernardi G.

Clin Ter. 1983 Feb 15;104(3):211-8. Italian. No abstract available.

PMID:
6861458

Supplemental Content

Loading ...
Support Center