Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 60

1.

Role of cathepsin S in ozone-induced airway hyperresponsiveness and inflammation.

Williams AS, Eynott PR, Leung SY, Nath P, Jupp R, De Sanctis GT, Resnick R, Adcock IM, Chung KF.

Pulm Pharmacol Ther. 2009 Feb;22(1):27-32. doi: 10.1016/j.pupt.2008.11.002. Epub 2008 Nov 14.

PMID:
19041950
2.

Ventilatory responses to acute hypoxia in neurokinin-1 receptor deficient mice.

Grasemann H, Gerard NP, De Sanctis GT.

Respir Physiol Neurobiol. 2007 Nov 15;159(2):227-31. Epub 2007 Aug 6.

PMID:
17869190
3.

Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats.

Tesfaigzi Y, McDonald JD, Reed MD, Singh SP, De Sanctis GT, Eynott PR, Hahn FF, Campen MJ, Mauderly JL.

Toxicol Sci. 2005 Dec;88(2):505-13. Epub 2005 Sep 14.

PMID:
16162849
4.

Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema.

Zheng T, Kang MJ, Crothers K, Zhu Z, Liu W, Lee CG, Rabach LA, Chapman HA, Homer RJ, Aldous D, De Sanctis GT, Underwood S, Graupe M, Flavell RA, Schmidt JA, Elias JA.

J Immunol. 2005 Jun 15;174(12):8106-15. Erratum in: J Immunol. 2005 Aug 1;175(3):2026. Desanctis, George [corrected to De Sanctis, George T].

5.

The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.

Doganci A, Eigenbrod T, Krug N, De Sanctis GT, Hausding M, Erpenbeck VJ, Haddad el-B, Lehr HA, Schmitt E, Bopp T, Kallen KJ, Herz U, Schmitt S, Luft C, Hecht O, Hohlfeld JM, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Renz H, Neurath MF, Galle PR, Finotto S.

J Clin Invest. 2005 Feb;115(2):313-25. Erratum in: J Clin Invest. 2005 May;115(5):1388. Lehr, Hans A [added].

6.

Nitric oxide synthase-2 down-regulates surfactant protein-B expression and enhances endotoxin-induced lung injury in mice.

Baron RM, Carvajal IM, Fredenburgh LE, Liu X, Porrata Y, Cullivan ML, Haley KJ, Sonna LA, De Sanctis GT, Ingenito EP, Perrella MA.

FASEB J. 2004 Aug;18(11):1276-8. Epub 2004 Jun 18.

PMID:
15208261
7.

Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness.

Hjoberg J, Shore S, Kobzik L, Okinaga S, Hallock A, Vallone J, Subramaniam V, De Sanctis GT, Elias JA, Drazen JM, Silverman ES.

J Appl Physiol (1985). 2004 Jul;97(1):249-59. Epub 2004 Mar 12.

8.

Lipoxins and aspirin-triggered lipoxins in airway responses.

Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt B, Szczeklik W, Drazen JM, Serhan CN.

Adv Exp Med Biol. 2003;525:19-23.

PMID:
12751730
9.

Molecular characterization of antigen-induced lung inflammation in a murine model of asthma.

Daheshia M, Tian N, Connolly T, Drawid A, Wu Q, Bienvenu JG, Cavallo J, Jupp R, De Sanctis GT, Minnich A.

Ann N Y Acad Sci. 2002 Dec;975:148-59.

PMID:
12538161
10.

Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia.

Tesfaigzi Y, Fischer MJ, Daheshia M, Green FH, De Sanctis GT, Wilder JA.

J Immunol. 2002 Nov 15;169(10):5919-25.

11.

Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).

Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt BA, Szczeklik W, Drazen JM, Serhan CN.

Nat Med. 2002 Sep;8(9):1018-23. Epub 2002 Aug 12.

PMID:
12172542
12.

Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation.

Haddad el-B, McCluskie K, Birrell MA, Dabrowski D, Pecoraro M, Underwood S, Chen B, De Sanctis GT, Webber SE, Foster ML, Belvisi MG.

J Immunol. 2002 Jul 15;169(2):974-82.

13.

IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.

Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y.

J Immunol. 2002 May 1;168(9):4764-71.

14.

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet.

Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FH, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, De Sanctis GT, Glimcher LH.

Science. 2002 Jan 11;295(5553):336-8.

15.

Genetics of allergen-induced asthma.

Daser A, Daheshia M, De Sanctis GT.

J Allergy Clin Immunol. 2001 Aug;108(2):167-74. Review.

PMID:
11496230
16.

Genetics of airway hyperresponsiveness.

De Sanctis GT, Daheshia M, Daser A.

J Allergy Clin Immunol. 2001 Jul;108(1):11-20. Review.

PMID:
11447377
17.

Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression.

Finotto S, De Sanctis GT, Lehr HA, Herz U, Buerke M, Schipp M, Bartsch B, Atreya R, Schmitt E, Galle PR, Renz H, Neurath MF.

J Exp Med. 2001 Jun 4;193(11):1247-60.

18.

Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lung.

Huang C, De Sanctis GT, O'Brien PJ, Mizgerd JP, Friend DS, Drazen JM, Brass LF, Stevens RL.

J Biol Chem. 2001 Jul 13;276(28):26276-84. Epub 2001 May 2.

19.

The transcription factor early growth-response factor 1 modulates tumor necrosis factor-alpha, immunoglobulin E, and airway responsiveness in mice.

Silverman ES, De Sanctis GT, Boyce J, Maclean JA, Jiao A, Green FH, Grasemann H, Faunce D, Fitzmaurice G, Shi GP, Stein-Streilein J, Milbrandt J, Collins T, Drazen JM.

Am J Respir Crit Care Med. 2001 Mar;163(3 Pt 1):778-85.

PMID:
11254538
20.

CC chemokine receptor-2 is not essential for the development of antigen-induced pulmonary eosinophilia and airway hyperresponsiveness.

MacLean JA, De Sanctis GT, Ackerman KG, Drazen JM, Sauty A, DeHaan E, Green FH, Charo IF, Luster AD.

J Immunol. 2000 Dec 1;165(11):6568-75.

21.

B7-1 (CD80) and B7-2 (CD86) have complementary roles in mediating allergic pulmonary inflammation and airway hyperresponsiveness.

Mark DA, Donovan CE, De Sanctis GT, He HZ, Cernadas M, Kobzik L, Perkins DL, Sharpe A, Finn PW.

Am J Respir Cell Mol Biol. 2000 Mar;22(3):265-71.

PMID:
10696062
22.

Quantitative trait locus mapping of airway responsiveness to chromosomes 6 and 7 in inbred mice.

De Sanctis GT, Singer JB, Jiao A, Yandava CN, Lee YH, Haynes TC, Lander ES, Beier DR, Drazen JM.

Am J Physiol. 1999 Dec;277(6):L1118-23. doi: 10.1152/ajplung.1999.277.6.L1118.

PMID:
10600881
23.

NF-kappa B/Rel transcription factors: c-Rel promotes airway hyperresponsiveness and allergic pulmonary inflammation.

Donovan CE, Mark DA, He HZ, Liou HC, Kobzik L, Wang Y, De Sanctis GT, Perkins DL, Finn PW.

J Immunol. 1999 Dec 15;163(12):6827-33.

24.

Targeted deletion of the neutral endopeptidase gene alters ventilatory responses to acute hypoxia in mice.

Grasemann H, Lu B, Jiao A, Boudreau J, Gerard NP, De Sanctis GT.

J Appl Physiol (1985). 1999 Oct;87(4):1266-71.

25.

Mutations in the human 5-lipoxygenase gene.

In KH, Silverman ES, Asano K, Beier D, Fischer AR, Keith TP, Serino K, Yandava C, De Sanctis GT, Drazen JM.

Clin Rev Allergy Immunol. 1999 Spring-Summer;17(1-2):59-69.

PMID:
10436859
26.

Animal models of asthma and chronic bronchitis.

Drazen JM, Takebayashi T, Long NC, De Sanctis GT, Shore SA.

Clin Exp Allergy. 1999 Jun;29 Suppl 2:37-47. Review.

PMID:
10421821
27.

Simple tandem repeat polymorphisms in the neuronal nitric oxide synthase gene in different ethnic populations.

Grasemann H, Drazen JM, Deykin A, Israel E, De Sanctis GT, Pillari A, Yandava CH.

Hum Hered. 1999 Jun;49(3):139-41.

PMID:
10364677
28.

Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma.

De Sanctis GT, MacLean JA, Hamada K, Mehta S, Scott JA, Jiao A, Yandava CN, Kobzik L, Wolyniec WW, Fabian AJ, Venugopal CS, Grasemann H, Huang PL, Drazen JM.

J Exp Med. 1999 May 17;189(10):1621-30.

29.
30.

Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice.

MacLean JA, Sauty A, Luster AD, Drazen JM, De Sanctis GT.

Am J Respir Cell Mol Biol. 1999 Mar;20(3):379-87.

PMID:
10030835
31.

Interleukin-8 receptor modulates IgE production and B-cell expansion and trafficking in allergen-induced pulmonary inflammation.

De Sanctis GT, MacLean JA, Qin S, Wolyniec WW, Grasemann H, Yandava CN, Jiao A, Noonan T, Stein-Streilein J, Green FH, Drazen JM.

J Clin Invest. 1999 Feb;103(4):507-15.

32.

CD23 and allergic pulmonary inflammation: potential role as an inhibitor.

Cernadas M, De Sanctis GT, Krinzman SJ, Mark DA, Donovan CE, Listman JA, Kobzik L, Kikutani H, Christiani DC, Perkins DL, Finn PW.

Am J Respir Cell Mol Biol. 1999 Jan;20(1):1-8.

PMID:
9870911
33.

Both CD80 and CD86 co-stimulatory molecules regulate allergic pulmonary inflammation.

Mark DA, Donovan CE, De Sanctis GT, Krinzman SJ, Kobzik L, Linsley PS, Sayegh MH, Lederer J, Perkins DL, Finn PW.

Int Immunol. 1998 Nov;10(11):1647-55.

PMID:
9846693
34.

Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants.

Silverman ES, Du J, De Sanctis GT, Rådmark O, Samuelsson B, Drazen JM, Collins T.

Am J Respir Cell Mol Biol. 1998 Aug;19(2):316-23.

PMID:
9698605
35.

Ventilatory responses in awake guinea pigs exposed to acid aerosols.

Roth SH, Bjarnason SG, De Sanctis GT, Feroah T, Jiang X, Karkhanis A, Green FH.

J Toxicol Environ Health A. 1998 Jun 26;54(4):261-83.

PMID:
9638899
36.

Reduction of antigen-induced airway hyperreactivity and eosinophilia in ICAM-1-deficient mice.

Wolyniec WW, De Sanctis GT, Nabozny G, Torcellini C, Haynes N, Joetham A, Gelfand EW, Drazen JM, Noonan TC.

Am J Respir Cell Mol Biol. 1998 Jun;18(6):777-85.

PMID:
9618382
37.

Cathepsin S activity regulates antigen presentation and immunity.

Riese RJ, Mitchell RN, Villadangos JA, Shi GP, Palmer JT, Karp ER, De Sanctis GT, Ploegh HL, Chapman HA.

J Clin Invest. 1998 Jun 1;101(11):2351-63.

38.

Contribution of type I NOS to expired gas NO and bronchial responsiveness in mice.

De Sanctis GT, Mehta S, Kobzik L, Yandava C, Jiao A, Huang PL, Drazen JM.

Am J Physiol. 1997 Oct;273(4):L883-8. doi: 10.1152/ajplung.1997.273.4.L883.

PMID:
9357865
39.

Genetics of native airway responsiveness in mice.

De Sanctis GT, Drazen JM.

Am J Respir Crit Care Med. 1997 Oct;156(4 Pt 2):S82-8. Review.

PMID:
9351585
40.

Reduction of allergic airway responses in P-selectin-deficient mice.

De Sanctis GT, Wolyniec WW, Green FH, Qin S, Jiao A, Finn PW, Noonan T, Joetham AA, Gelfand E, Doerschuk CM, Drazen JM.

J Appl Physiol (1985). 1997 Sep;83(3):681-7.

41.

T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice.

De Sanctis GT, Itoh A, Green FH, Qin S, Kimura T, Grobholz JK, Martin TR, Maki T, Drazen JM.

Nat Med. 1997 Apr;3(4):460-2.

PMID:
9095183
42.

Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription.

In KH, Asano K, Beier D, Grobholz J, Finn PW, Silverman EK, Silverman ES, Collins T, Fischer AR, Keith TP, Serino K, Kim SW, De Sanctis GT, Yandava C, Pillari A, Rubin P, Kemp J, Israel E, Busse W, Ledford D, Murray JJ, Segal A, Tinkleman D, Drazen JM.

J Clin Invest. 1997 Mar 1;99(5):1130-7.

43.

Genetics of airway responsiveness in the inbred mouse.

De Sanctis GT, Drazen JM.

Res Immunol. 1997 Jan;148(1):73-9; discussion 79-83. Review. No abstract available.

PMID:
9176921
44.

Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model.

Krinzman SJ, De Sanctis GT, Cernadas M, Mark D, Wang Y, Listman J, Kobzik L, Donovan C, Nassr K, Katona I, Christiani DC, Perkins DL, Finn PW.

J Clin Invest. 1996 Dec 15;98(12):2693-9.

45.

T cell activation in a murine model of asthma.

Krinzman SJ, De Sanctis GT, Cernadas M, Kobzik L, Listman JA, Christiani DC, Perkins DL, Finn PW.

Am J Physiol. 1996 Sep;271(3 Pt 1):L476-83.

PMID:
8843798
46.

A comparison of a new mucolytic N-acetylcysteine L-lysinate with N-acetylcysteine: airway epithelial function and mucus changes in dog.

Tomkiewicz RP, App EM, De Sanctis GT, Coffiner M, Maes P, Rubin BK, King M.

Pulm Pharmacol. 1995 Dec;8(6):259-65.

PMID:
8819180
47.

Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice.

De Sanctis GT, Merchant M, Beier DR, Dredge RD, Grobholz JK, Martin TR, Lander ES, Drazen JM.

Nat Genet. 1995 Oct;11(2):150-4.

PMID:
7550342
48.

Species differences in the physical and transport properties of airway secretions.

Tomkiewicz RP, Albers GM, De Sanctis GT, Ramirez OE, King M, Rubin BK.

Can J Physiol Pharmacol. 1995 Feb;73(2):165-71. Review.

PMID:
7621353
49.

Exogenous surfactant enhances mucociliary clearance in the anaesthetized dog.

De Sanctis GT, Tomkiewicz RP, Rubin BK, Schürch S, King M.

Eur Respir J. 1994 Sep;7(9):1616-21.

50.

Ventilatory responses to hypoxia in rats pretreated with nonpeptide NK1 receptor antagonist CP-96,345.

De Sanctis GT, Green FH, Jiang X, King M, Remmers JE.

J Appl Physiol (1985). 1994 Apr;76(4):1528-32.

PMID:
7519186

Supplemental Content

Loading ...
Support Center