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Lithium chloride increases sensitivity to photon irradiation treatment in primary mesenchymal colon cancer cells.

Cammarota F, Conte A, Aversano A, Muto P, Ametrano G, Riccio P, Turano M, Valente V, Delrio P, Izzo P, Pierantoni GM, De Rosa M.

Mol Med Rep. 2020 Jan 21. doi: 10.3892/mmr.2020.10956. [Epub ahead of print]


β-cyclodextrin coating: improving biocompatibility of magnetic nanocomposites for biomedical applications.

Agotegaray M, Blanco MG, Campelo A, García E, Zysler R, Massheimer V, De Rosa MJ, Lassalle V.

J Mater Sci Mater Med. 2020 Jan 30;31(2):22. doi: 10.1007/s10856-020-6361-4.


Safety of hospital discharge before return of bowel function after elective colorectal surgery.

EuroSurg Collaborative.

Br J Surg. 2020 Jan 24. doi: 10.1002/bjs.11422. [Epub ahead of print]


New compounds for a good old class: Synthesis of two Β-lactam bearing cephalosporins and their evaluation with a multidisciplinary approach.

Vigliotta G, Giordano D, Verdino A, Caputo I, Martucciello S, Soriente A, Marabotti A, De Rosa M.

Bioorg Med Chem. 2020 Feb 15;28(4):115302. doi: 10.1016/j.bmc.2019.115302. Epub 2020 Jan 3.


Prismarenes: A New Class of Macrocyclic Hosts Obtained by Templation in a Thermodynamically Controlled Synthesis.

Della Sala P, Del Regno R, Talotta C, Capobianco A, Hickey N, Geremia S, De Rosa M, Spinella A, Soriente A, Neri P, Gaeta C.

J Am Chem Soc. 2020 Jan 29;142(4):1752-1756. doi: 10.1021/jacs.9b12216. Epub 2020 Jan 15.


Promising Colorectal Cancer Biomarkers for Precision Prevention and Therapy.

Turano M, Delrio P, Rega D, Cammarota F, Polverino A, Duraturo F, Izzo P, De Rosa M.

Cancers (Basel). 2019 Dec 4;11(12). pii: E1932. doi: 10.3390/cancers11121932. Review.


Hyaluronan-based hydrogels via ether-crosslinking: Is HA molecular weight an effective means to tune gel performance?

La Gatta A, Salzillo R, Catalano C, Pirozzi AVA, D'Agostino A, Bedini E, Cammarota M, De Rosa M, Schiraldi C.

Int J Biol Macromol. 2020 Feb 1;144:94-101. doi: 10.1016/j.ijbiomac.2019.11.227. Epub 2019 Nov 30.


The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.

de Rosa M, Barbiroli A, Bonì F, Scalone E, Mattioni D, Vanoni MA, Patrone M, Bollati M, Mastrangelo E, Giorgino T, Milani M.

Eur Biophys J. 2020 Jan;49(1):11-19. doi: 10.1007/s00249-019-01409-9. Epub 2019 Nov 13.


The Hexameric Resorcinarene Capsule as a Brønsted Acid Catalyst for the Synthesis of Bis(heteroaryl)methanes in a Nanoconfined Space.

Gambaro S, La Manna P, De Rosa M, Soriente A, Talotta C, Gaeta C, Neri P.

Front Chem. 2019 Oct 22;7:687. doi: 10.3389/fchem.2019.00687. eCollection 2019.


Current and emerging medications for borderline personality disorder: is pharmacotherapy alone enough?

Bozzatello P, Rocca P, De Rosa ML, Bellino S.

Expert Opin Pharmacother. 2020 Jan;21(1):47-61. doi: 10.1080/14656566.2019.1686482. Epub 2019 Nov 6. Review.


Synergic Interplay Between Halogen Bonding and Hydrogen Bonding in the Activation of a Neutral Substrate in a Nanoconfined Space.

La Manna P, De Rosa M, Talotta C, Rescifina A, Floresta G, Soriente A, Gaeta C, Neri P.

Angew Chem Int Ed Engl. 2020 Jan 7;59(2):811-818. doi: 10.1002/anie.201909865. Epub 2019 Nov 27.


In Silico Insights towards the Identification of NLRP3 Druggable Hot Spots.

Mekni N, De Rosa M, Cipollina C, Gulotta MR, De Simone G, Lombino J, Padova A, Perricone U.

Int J Mol Sci. 2019 Oct 9;20(20). pii: E4974. doi: 10.3390/ijms20204974.


Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery.

EuroSurg Collaborative.

Br J Surg. 2020 Jan;107(2):e161-e169. doi: 10.1002/bjs.11326. Epub 2019 Oct 9.


Multiple threading of a triple-calix[6]arene host.

Iuliano V, Ciao R, Vignola E, Talotta C, Iannece P, De Rosa M, Soriente A, Gaeta C, Neri P.

Beilstein J Org Chem. 2019 Sep 3;15:2092-2104. doi: 10.3762/bjoc.15.207. eCollection 2019.


In Vitro Evaluation of Novel Hybrid Cooperative Complexes in a Wound Healing Model: A Step Toward Improved Bioreparation.

D'Agostino A, Maritato R, La Gatta A, Fusco A, Reale S, Stellavato A, Pirozzi AVA, De Rosa M, Donnarumma G, Schiraldi C.

Int J Mol Sci. 2019 Sep 24;20(19). pii: E4727. doi: 10.3390/ijms20194727.


Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer.

Mitran B, Varasteh Z, Abouzayed A, Rinne SS, Puuvuori E, De Rosa M, Larhed M, Tolmachev V, Orlova A, Rosenström U.

Cancers (Basel). 2019 Sep 14;11(9). pii: E1371. doi: 10.3390/cancers11091371.


Comparative Analyses of Pharmaceuticals or Food Supplements Containing Chondroitin Sulfate: Are Their Bioactivities Equivalent?

Stellavato A, Restaino OF, Vassallo V, Finamore R, Ruosi C, Cassese E, De Rosa M, Schiraldi C.

Adv Ther. 2019 Nov;36(11):3221-3237. doi: 10.1007/s12325-019-01064-8. Epub 2019 Sep 7.


The flight response impairs cytoprotective mechanisms by activating the insulin pathway.

De Rosa MJ, Veuthey T, Florman J, Grant J, Blanco MG, Andersen N, Donnelly J, Rayes D, Alkema MJ.

Nature. 2019 Sep;573(7772):135-138. doi: 10.1038/s41586-019-1524-5. Epub 2019 Aug 28.


The uPAR System as a Potential Therapeutic Target in the Diseased Eye.

Cammalleri M, Dal Monte M, Pavone V, De Rosa M, Rusciano D, Bagnoli P.

Cells. 2019 Aug 18;8(8). pii: E925. doi: 10.3390/cells8080925. Review.


Threading of Conformationally Stable Calix[6]arene Wheels Substituted at the Methylene Bridges.

Tranfić Bakić M, Iuliano V, Talotta C, Geremia S, Hickey N, Spinella A, De Rosa M, Soriente A, Gaeta C, Neri P.

J Org Chem. 2019 Sep 20;84(18):11922-11927. doi: 10.1021/acs.joc.9b01779. Epub 2019 Sep 6.


High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion.

Bollati M, Scalone E, Bonì F, Mastrangelo E, Giorgino T, Milani M, de Rosa M.

Biochem Biophys Res Commun. 2019 Oct 8;518(1):94-99. doi: 10.1016/j.bbrc.2019.08.013. Epub 2019 Aug 12.


Novel variants of unknown significance in the PMS2 gene identified in patients with hereditary colon cancer.

Liccardo R, Della Ragione C, Mitilini N, De Rosa M, Izzo P, Duraturo F.

Cancer Manag Res. 2019 Jul 18;11:6719-6725. doi: 10.2147/CMAR.S167348. eCollection 2019.


Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors.

Boccellino M, Donniacuo M, Bruno F, Rinaldi B, Quagliuolo L, Ambruosi M, Pace S, De Rosa M, Olgaç A, Banoglu E, Alessio N, Massa A, Kahn H, Werz O, Fiorentino A, Filosa R.

Eur J Med Chem. 2019 Oct 15;180:637-647. doi: 10.1016/j.ejmech.2019.07.033. Epub 2019 Jul 10.


An alternative non-proteolytic mechanism may underlie AGel amyloidosis.

Bonì F, Milani M, Mastrangelo E, Babiroli A, Diomede L, de Rosa M.

Amyloid. 2019;26(sup1):150-151. doi: 10.1080/13506129.2019.1582510. No abstract available.


European chondroitin sulfate and glucosamine food supplements: A systematic quality and quantity assessment compared to pharmaceuticals.

Restaino OF, Finamore R, Stellavato A, Diana P, Bedini E, Trifuoggi M, De Rosa M, Schiraldi C.

Carbohydr Polym. 2019 Oct 15;222:114984. doi: 10.1016/j.carbpol.2019.114984. Epub 2019 Jun 20.


Robot-assisted Toupet fundoplication and associated cholecystectomy in symptomatic giant hiatal hernia with situs viscerum inversus-A case report and literature review.

Ceccarelli G, Romano A, Esposito G, De Rosa M, Bugiantella W, Miranda E, Fontani A, D'Andrea V.

Int J Surg Case Rep. 2019;60:371-375. doi: 10.1016/j.ijscr.2019.06.038. Epub 2019 Jun 22.


Synthesis, Characterization, and Solid-State Structure of [8]Cycloparaphenylenes with Inherent Chirality.

Della Sala P, Talotta C, De Rosa M, Soriente A, Geremia S, Hickey N, Neri P, Gaeta C.

J Org Chem. 2019 Aug 2;84(15):9489-9496. doi: 10.1021/acs.joc.9b01026. Epub 2019 Jul 19.


The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: New pre-clinical evidence in the rd10 mouse model.

Cammalleri M, Dal Monte M, Locri F, Pecci V, De Rosa M, Pavone V, Bagnoli P.

J Cell Mol Med. 2019 Aug;23(8):5176-5192. doi: 10.1111/jcmm.14391. Epub 2019 Jun 28.


Video-robotic aneurismectomy for splenic artery aneurysm: case report and literature review.

Ceccarelli G, Gusai G, Rondelli F, Balestra F, De Rosa M.

Minim Invasive Ther Allied Technol. 2019 Jun 28:1-6. doi: 10.1080/13645706.2019.1623819. [Epub ahead of print]


UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis.

Locri F, Dal Monte M, Aronsson M, Cammalleri M, De Rosa M, Pavone V, Kvanta A, Bagnoli P, André H.

J Mol Med (Berl). 2019 Sep;97(9):1273-1283. doi: 10.1007/s00109-019-01794-w. Epub 2019 Jun 26.


Hyaluronic acid and chondroitin sulfate, alone or in combination, efficiently counteract induced bladder cell damage and inflammation.

Stellavato A, Pirozzi AVA, Diana P, Reale S, Vassallo V, Fusco A, Donnarumma G, De Rosa M, Schiraldi C.

PLoS One. 2019 Jun 25;14(6):e0218475. doi: 10.1371/journal.pone.0218475. eCollection 2019.


Hyaluronan-based hydrogels as dermal fillers: The biophysical properties that translate into a "volumetric" effect.

La Gatta A, Salzillo R, Catalano C, D'Agostino A, Pirozzi AVA, De Rosa M, Schiraldi C.

PLoS One. 2019 Jun 11;14(6):e0218287. doi: 10.1371/journal.pone.0218287. eCollection 2019.


Novel Hybrid Gels Made of High and Low Molecular Weight Hyaluronic Acid Induce Proliferation and Reduce Inflammation in an Osteoarthritis In Vitro Model Based on Human Synoviocytes and Chondrocytes.

Stellavato A, Vassallo V, La Gatta A, Pirozzi AVA, De Rosa M, Balato G, D'Addona A, Tirino V, Ruosi C, Schiraldi C.

Biomed Res Int. 2019 Apr 23;2019:4328219. doi: 10.1155/2019/4328219. eCollection 2019.


Targeting Neuropathic Pain: Pathobiology, Current Treatment and Peptidomimetics as a New Therapeutic Opportunity.

Caroleo MC, Brizzi A, De Rosa M, Pandey A, Gallelli L, Badolato M, Carullo G, Cione E.

Curr Med Chem. 2019 May 30. doi: 10.2174/0929867326666190530121133. [Epub ahead of print]


Mapping the medical outcomes study HIV health survey (MOS-HIV) to the EuroQoL 5 Dimension (EQ-5D-3 L) utility index.

Shi Y, Thompson J, Walker AS, Paton NI, Cheung YB; EARNEST Trial Team.

Health Qual Life Outcomes. 2019 May 10;17(1):83. doi: 10.1186/s12955-019-1135-8.


Age of HIV Acquisition Affects the Risk of Multi-Morbidity after 25 Years of Infection Exposure.

Guaraldi G, Malagoli A, Milic J, Pintassilgo I, Rossi E, Riva N, Franconi I, Santoro A, Sorin P, Streinu-Cercel A, De Rosa M, Mussini C.

J Frailty Aging. 2019;8(2):88-92. doi: 10.14283/jfa.2019.6.


Selective Inhibitors of T Cell Receptor Recognition of Antigen-MHC Complexes for Rheumatoid Arthritis.

Ria F, Pirolli D, Di Sante G, Righino B, Gremese E, Gervasoni J, Nicolò C, Giardina B, Ferraccioli G, De Rosa MC.

ACS Med Chem Lett. 2019 Mar 13;10(4):644-649. doi: 10.1021/acsmedchemlett.8b00601. eCollection 2019 Apr 11.


Negative Solvatochromism in a N-Linked p-Pyridiniumcalix[4]arene Derivative.

Iuliano V, Talotta C, Gaeta C, Soriente A, De Rosa M, Geremia S, Hickey N, Mennucci B, Neri P.

Org Lett. 2019 Apr 19;21(8):2704-2707. doi: 10.1021/acs.orglett.9b00683. Epub 2019 Apr 2.


Genetics, diagnosis and treatment of Lynch syndrome: Old lessons and current challenges.

Duraturo F, Liccardo R, De Rosa M, Izzo P.

Oncol Lett. 2019 Mar;17(3):3048-3054. doi: 10.3892/ol.2019.9945. Epub 2019 Jan 18. Review.


RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones.

Pezone A, Zuchegna C, Tramontano A, Romano A, Russo G, de Rosa M, Vinciguerra M, Porcellini A, Gottesman ME, Avvedimento EV.

Sci Rep. 2019 Mar 8;9(1):3925. doi: 10.1038/s41598-019-40123-6.


Characterization of Rare Variants in MC4R in African American and Latino Children With Severe Early-Onset Obesity.

De Rosa MC, Chesi A, McCormack S, Zhou J, Weaver B, McDonald M, Christensen S, Liimatta K, Rosenbaum M, Hakonarson H, Doege CA, Grant SFA, Hirschhorn JN, Thaker VV.

J Clin Endocrinol Metab. 2019 Jul 1;104(7):2961-2970. doi: 10.1210/jc.2018-02657.


Green, Mild, and Efficient Friedel-Crafts Benzylation of Scarcely Reactive Arenes and Heteroarenes under On-Water Conditions.

La Manna P, Soriente A, De Rosa M, Buonerba A, Talotta C, Gaeta C, Neri P.

ChemSusChem. 2019 Apr 23;12(8):1673-1683. doi: 10.1002/cssc.201900137. Epub 2019 Mar 19.


Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development.

Wang L, De Solis AJ, Goffer Y, Birkenbach KE, Engle SE, Tanis R, Levenson JM, Li X, Rausch R, Purohit M, Lee JY, Tan J, De Rosa MC, Doege CA, Aaron HL, Martins GJ, Brüning JC, Egli D, Costa R, Berbari N, Leibel RL, Stratigopoulos G.

JCI Insight. 2019 Feb 7;4(3). pii: 123337. doi: 10.1172/jci.insight.123337. [Epub ahead of print]


Parathyroid Hormone Causes Endothelial Dysfunction by Inducing Mitochondrial ROS and Specific Oxidative Signal Transduction Modifications.

Gambardella J, De Rosa M, Sorriento D, Prevete N, Fiordelisi A, Ciccarelli M, Trimarco B, De Luca N, Iaccarino G.

Oxid Med Cell Longev. 2018 Dec 19;2018:9582319. doi: 10.1155/2018/9582319. eCollection 2018.


Hormones and Auditory Perception: Study of Dichotic Listening in Women during the Menstrual Cycle.

Carneiro CDS, Almeida AAF, Ribas A, Kluk-De Kort K, Lima DO, Araújo AMGD, Ferreira DAH, Martins ML, Freitas TMMWC, de Rosa MRD.

Int Arch Otorhinolaryngol. 2019 Jan;23(1):70-76. doi: 10.1055/s-0038-1626701. Epub 2018 May 9.


Characterization of a male specific region containing a candidate sex determining gene in Atlantic cod.

Kirubakaran TG, Andersen Ø, De Rosa MC, Andersstuen T, Hallan K, Kent MP, Lien S.

Sci Rep. 2019 Jan 15;9(1):116. doi: 10.1038/s41598-018-36748-8.


Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.

Giorgino T, Mattioni D, Hassan A, Milani M, Mastrangelo E, Barbiroli A, Verhelle A, Gettemans J, Barzago MM, Diomede L, de Rosa M.

Biochim Biophys Acta Mol Basis Dis. 2019 Mar 1;1865(3):648-660. doi: 10.1016/j.bbadis.2019.01.010. Epub 2019 Jan 6.


Diisopropylphenyl-imidazole (DII): A new compound that exerts anthelmintic activity through novel molecular mechanisms.

Blanco MG, Vela Gurovic MS, Silbestri GF, Garelli A, Giunti S, Rayes D, De Rosa MJ.

PLoS Negl Trop Dis. 2018 Dec 17;12(12):e0007021. doi: 10.1371/journal.pntd.0007021. eCollection 2018 Dec.


DNA damage signatures in peripheral blood cells as biomarkers in prodromal huntington disease.

Castaldo I, De Rosa M, Romano A, Zuchegna C, Squitieri F, Mechelli R, Peluso S, Borrelli C, Del Mondo A, Salvatore E, Vescovi LA, Migliore S, De Michele G, Ristori G, Romano S, Avvedimento EV, Porcellini A.

Ann Neurol. 2019 Feb;85(2):296-301. doi: 10.1002/ana.25393. Epub 2019 Jan 13.


A Novel Small Peptide Inhibitor of NFκB, RH10, Blocks Oxidative Stress-Dependent Phenotypes in Cancer.

Gambardella J, Ciccarelli M, Del Giudice C, Fiordelisi A, De Rosa M, Sala M, Pacelli R, Campiglia P, Trimarco B, Iaccarino G, Sorriento D.

Oxid Med Cell Longev. 2018 Nov 4;2018:5801807. doi: 10.1155/2018/5801807. eCollection 2018.

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