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Results of API-AI based regimen in osteosarcoma adult patients included in the French OS2006/Sarcome-09 study.

Piperno-Neumann S, Ray-Coquard I, Occean BV, Laurence V, Cupissol D, Perrin C, Penel N, Bompas E, Rios M, Le Cesne A, Italiano A, Anract P, de Pinieux G, Collard O, Bertucci F, Duffaud F, Le Deley MC, Delaye J, Brugieres L, Blay JY.

Int J Cancer. 2019 Jun 27. doi: 10.1002/ijc.32526. [Epub ahead of print]


ETIOSARC study : environmental aetiology of sarcomas from a French prospective multicentric population-based case-control study-study protocol.

Lacourt A, Amadéo B, Gramond C, Marrer E, Plouvier S, Baldi I, Blay JY, Coindre JM, de Pinieux G, Gouin F, Italiano A, Le Cesne A, Le Loarer F, Monnereau A, Pellegrin I, Penel N, Ray-Coquard I, Toulmonde M, Ducimetière F, Mathoulin-Pélissier S; Etiosarc study group.

BMJ Open. 2019 Jun 18;9(6):e030013. doi: 10.1136/bmjopen-2019-030013.


Assessment of resection margins in bone sarcoma treated by neoadjuvant chemotherapy: Literature review and guidelines of the bone group (GROUPOS) of the French sarcoma group and bone tumor study group (GSF-GETO/RESOS).

Gomez-Brouchet A, Mascard E, Siegfried A, de Pinieux G, Gaspar N, Bouvier C, Aubert S, Marec-Bérard P, Piperno-Neumann S, Marie B, Larousserie F, Galant C, Fiorenza F, Anract P, Sales de Gauzy J, Gouin F; GROUPOS (GSF-GETO RESOS).

Orthop Traumatol Surg Res. 2019 Jun;105(4):773-780. doi: 10.1016/j.otsr.2018.12.015. Epub 2019 Apr 5. Review.


Acute Tibial osteomyelitis caused by intraosseous access during initial resuscitation: a case report and literature review.

Chalopin T, Lemaignen A, Guillon A, Geffray A, Derot G, Bahuaud O, Agout C, Rosset P, Castellier C, De Pinieux G, Valentin AS, Bernard L, Bastides F; Centre De Référence Des Infections Ostéo-Articulaires Du Grand-Ouest (CRIOGO) Study Team.

BMC Infect Dis. 2018 Dec 17;18(1):665. doi: 10.1186/s12879-018-3577-8. Review.


Vertical Bone Regeneration with Synthetic Biomimetic Calcium Phosphate onto the Calvaria of Rats.

Hoornaert A, Maazouz Y, Pastorino D, Aparicio C, de Pinieux G, Fellah BH, Ginebra MP, Layrolle P.

Tissue Eng Part C Methods. 2019 Jan;25(1):1-11. doi: 10.1089/ten.TEC.2018.0260.


Geographical Accessibility of the Referral Networks in France. Intermediate Results from the IGéAS Research Program.

Fayet Y, Coindre JM, Dalban C, Gouin F, De Pinieux G, Farsi F, Ducimetière F, Chemin-Airiau C, Jean-Denis M, Chabaud S, Blay JY, Ray-Coquard I.

Int J Environ Res Public Health. 2018 Oct 10;15(10). pii: E2204. doi: 10.3390/ijerph15102204.


IDH mutation status in a series of 88 head and neck chondrosarcomas: different profile between tumors of the skull base and tumors involving the facial skeleton and the laryngotracheal tract.

Tallegas M, Miquelestorena-Standley É, Labit-Bouvier C, Badoual C, Francois A, Gomez-Brouchet A, Aubert S, Collin C, Tallet A, de Pinieux G.

Hum Pathol. 2019 Feb;84:183-191. doi: 10.1016/j.humpath.2018.09.015. Epub 2018 Oct 5.


Localized Myxofibrosarcomas: Roles of Surgical Margins and Adjuvant Radiation Therapy.

Boughzala-Bennadji R, Stoeckle E, Le Péchoux C, Méeus P, Honoré C, Attal J, Duffaud F, De Pinieux G, Bompas E, Thariat J, Leroux A, Bertucci F, Isambert N, Delcambre C, Blay JY, Sunyach MP, Coindre JM, Sargos P, Penel N, Bonvalot S.

Int J Radiat Oncol Biol Phys. 2018 Oct 1;102(2):399-406. doi: 10.1016/j.ijrobp.2018.05.055. Epub 2018 Jun 2.


Histopathological Diagnosis of Prosthetic Joint Infection: Does a Threshold of 23 Neutrophils Do Better than Classification of the Periprosthetic Membrane in a Prospective Multicenter Study?

Bémer P, Léger J, Milin S, Plouzeau C, Valentin AS, Stock N, Jolivet-Gougeon A, Moreau A, Corvec S, Quintin-Roue I, Tandé D, Héry-Arnaud G, Rousselet MC, Lemarié C, Kempf M, Michenet P, Bret L, de Pinieux G, Burucoa C; CRIOGO (Centre de Référence des Infections Ostéo-articulaires du Grand Ouest) Study Team.

J Clin Microbiol. 2018 Aug 27;56(9). pii: e00536-18. doi: 10.1128/JCM.00536-18. Print 2018 Sep.


[Benign and malignant giant-cell rich lesions of bone: Pathological diagnosis with special emphasis on recent immunohistochemistry and molecular techniques].

Macagno N, Caselles K, Aubert S, Audard V, Gomez-Brouchet A, Galant C, Guinebretière JM, Karanian M, Larousserie F, Marie B, de Pinieux G, Bouvier C.

Ann Pathol. 2018 Apr;38(2):92-102. doi: 10.1016/j.annpat.2018.01.008. Epub 2018 Mar 23. Review. French.


Comparison of Tumor- and Bone Marrow-Derived Mesenchymal Stromal/Stem Cells from Patients with High-Grade Osteosarcoma.

Le Nail LR, Brennan M, Rosset P, Deschaseaux F, Piloquet P, Pichon O, Le Caignec C, Crenn V, Layrolle P, Hérault O, De Pinieux G, Trichet V.

Int J Mol Sci. 2018 Mar 1;19(3). pii: E707. doi: 10.3390/ijms19030707.


Presentation and outcome of frequent and rare sarcoma histologic subtypes: A study of 10,262 patients with localized visceral/soft tissue sarcoma managed in reference centers.

Penel N, Coindre JM, Giraud A, Terrier P, Ranchere-Vince D, Collin F, Guellec SLE, Bazille C, Lae M, de Pinieux G, Ray-Coquard IL, Bonvalot S, Cesne ALE, Robin YM, Stoeckle E, Toulmonde M, Blay JY.

Cancer. 2018 Mar 15;124(6):1179-1187. doi: 10.1002/cncr.31176. Epub 2017 Dec 6.


CD163-positive tumor-associated macrophages and CD8-positive cytotoxic lymphocytes are powerful diagnostic markers for the therapeutic stratification of osteosarcoma patients: An immunohistochemical analysis of the biopsies fromthe French OS2006 phase 3 trial.

Gomez-Brouchet A, Illac C, Gilhodes J, Bouvier C, Aubert S, Guinebretiere JM, Marie B, Larousserie F, Entz-Werlé N, de Pinieux G, Filleron T, Minard V, Minville V, Mascard E, Gouin F, Jimenez M, Ledeley MC, Piperno-Neumann S, Brugieres L, Rédini F.

Oncoimmunology. 2017 Aug 24;6(9):e1331193. doi: 10.1080/2162402X.2017.1331193. eCollection 2017.


Paravertebral Well-Differentiated Liposarcoma with Low-Grade Osteosarcomatous Component: Case Report with 11-Year Follow-Up, Radiological, Pathological, and Genetic Data, and Literature Review.

Macagno N, Fuentes S, de Pinieux G, Maues de Paula A, Salas S, Mattéi JC, Dupuis C, Appay R, Aurias A, Dufour H, Figarella-Branger D, Bouvier C.

Case Rep Pathol. 2017;2017:2346316. doi: 10.1155/2017/2346316. Epub 2017 Mar 9.


Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells.

Franzetti GA, Laud-Duval K, van der Ent W, Brisac A, Irondelle M, Aubert S, Dirksen U, Bouvier C, de Pinieux G, Snaar-Jagalska E, Chavrier P, Delattre O.

Oncogene. 2017 Jun 22;36(25):3505-3514. doi: 10.1038/onc.2016.498. Epub 2017 Jan 30.


DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.

Sheffield NC, Pierron G, Klughammer J, Datlinger P, Schönegger A, Schuster M, Hadler J, Surdez D, Guillemot D, Lapouble E, Freneaux P, Champigneulle J, Bouvier R, Walder D, Ambros IM, Hutter C, Sorz E, Amaral AT, de Álava E, Schallmoser K, Strunk D, Rinner B, Liegl-Atzwanger B, Huppertz B, Leithner A, de Pinieux G, Terrier P, Laurence V, Michon J, Ladenstein R, Holter W, Windhager R, Dirksen U, Ambros PF, Delattre O, Kovar H, Bock C, Tomazou EM.

Nat Med. 2017 Mar;23(3):386-395. doi: 10.1038/nm.4273. Epub 2017 Jan 30.


H3F3 mutation status of giant cell tumors of the bone, chondroblastomas and their mimics: a combined high resolution melting and pyrosequencing approach.

Kervarrec T, Collin C, Larousserie F, Bouvier C, Aubert S, Gomez-Brouchet A, Marie B, Miquelestorena-Standley E, Le Nail LR, Avril P, Christophe Pagès J, de Pinieux G.

Mod Pathol. 2017 Mar;30(3):393-406. doi: 10.1038/modpathol.2016.212. Epub 2017 Jan 6.


Rapid maxillary expansion in adults: Can multislice computed tomography help choose between orthopedic or surgical treatment?

Gueutier A, Paré A, Joly A, Laure B, de Pinieux G, Goga D.

Rev Stomatol Chir Maxillofac Chir Orale. 2016 Nov;117(5):327-334. doi: 10.1016/j.revsto.2016.06.002. Epub 2016 Jul 4.


Anatomy and relations of the infraspinatus and the teres minor muscles: a fresh cadaver dissection study.

Bacle G, Gregoire JM, Patat F, Clavert P, de Pinieux G, Laulan J, Lakhal W, Favard L.

Surg Radiol Anat. 2017 Feb;39(2):119-126. doi: 10.1007/s00276-016-1707-9. Epub 2016 Jun 10.


Mesenchymal stem cells increase proliferation but do not change quiescent state of osteosarcoma cells: Potential implications according to the tumor resection status.

Avril P, Le Nail LR, Brennan MÁ, Rosset P, De Pinieux G, Layrolle P, Heymann D, Perrot P, Trichet V.

J Bone Oncol. 2015 Dec 12;5(1):5-14. doi: 10.1016/j.jbo.2015.11.002. eCollection 2016 Mar.


A new subtype of high-grade mandibular osteosarcoma with RASAL1/MDM2 amplification.

Guérin M, Thariat J, Ouali M, Bouvier C, Decouvelaere AV, Cassagnau E, Aubert S, Lepreux S, Coindre JM, Valmary-Degano S, Larousserie F, Meilleroux J, Projetti F, Stock N, Galant C, Marie B, Peyrottes I, de Pinieux G, Gomez-Brouchet A.

Hum Pathol. 2016 Apr;50:70-8. doi: 10.1016/j.humpath.2015.11.012. Epub 2015 Dec 9.


Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells.

Avril P, Duteille F, Ridel P, Heymann MF, De Pinieux G, Rédini F, Blanchard F, Heymann D, Trichet V, Perrot P.

Plast Reconstr Surg. 2016 Mar;137(3):865-75. doi: 10.1097/01.prs.0000479989.88114.8b.


Comments on Carter et al's "activating GNAS mutations in parosteal osteosarcoma".

Tabareau-Delalande F, Collin C, Larousserie F, Bouvier C, Gomez-Brouchet A, Aubert S, Guinebretière JM, Decouvelaere AV, de Muret A, Pagès JC, de Pinieux G.

Am J Surg Pathol. 2015 Jul;39(7):1010-3. doi: 10.1097/PAS.0000000000000461. No abstract available.


Serial lymphoscintigraphic findings in a patient with Gorham's disease with lymphedema.

Baulieu F, De Pinieux G, Maruani A, Vaillant L, Lorette G.

Lymphology. 2014 Sep;47(3):118-22.


A diagnosis of giant cell-rich tumour of bone is supported by p63 immunohistochemistry, when more than 50 % of cells is stained.

Maues De Paula A, Vasiljevic A, Giorgi R, Gomez-Brouchet A, Aubert S, Leroy X, Duval H, de Pinieux G, Bouvier C.

Virchows Arch. 2014 Oct;465(4):487-94. doi: 10.1007/s00428-014-1637-z. Epub 2014 Aug 7.


Evaluation of 16S rRNA gene PCR sensitivity and specificity for diagnosis of prosthetic joint infection: a prospective multicenter cross-sectional study.

Bémer P, Plouzeau C, Tande D, Léger J, Giraudeau B, Valentin AS, Jolivet-Gougeon A, Vincent P, Corvec S, Gibaud S, Juvin ME, Héry-Arnaud G, Lemarié C, Kempf M, Bret L, Quentin R, Coffre C, de Pinieux G, Bernard L, Burucoa C; Centre de Référence des Infections Ostéo-articulaires du Grand Ouest (CRIOGO) Study Team.

J Clin Microbiol. 2014 Oct;52(10):3583-9. doi: 10.1128/JCM.01459-14. Epub 2014 Jul 23.


Chromosome 12 long arm rearrangement covering MDM2 and RASAL1 is associated with aggressive craniofacial juvenile ossifying fibroma and extracranial psammomatoid fibro-osseous lesions.

Tabareau-Delalande F, Collin C, Gomez-Brouchet A, Bouvier C, Decouvelaere AV, de Muret A, Pagès JC, de Pinieux G.

Mod Pathol. 2015 Jan;28(1):48-56. doi: 10.1038/modpathol.2014.80. Epub 2014 Jun 13.


Cutaneous epithelioid clear cells angiosarcoma in a young woman with congenital lymphedema.

Tabareau-Delalande F, de Muret A, Miquelestorena-Standley E, Decouvelaere AV, de Pinieux G.

Case Rep Pathol. 2013;2013:931973. doi: 10.1155/2013/931973. Epub 2013 Sep 3.


[Becker's nevus and hemimaxillary hypoplasia: coincidence or syndrome?].

Petraud A, Sury F, Perrinaud A, de Pinieux G, Laure B, Goga D.

Rev Stomatol Chir Maxillofac Chir Orale. 2013 Feb;114(1):34-7. doi: 10.1016/j.revsto.2012.12.001. Epub 2013 Jan 30. French.


Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue.

Deschaseaux F, Gaillard J, Langonné A, Chauveau C, Naji A, Bouacida A, Rosset P, Heymann D, De Pinieux G, Rouas-Freiss N, Sensébé L.

FASEB J. 2013 Aug;27(8):2977-87. doi: 10.1096/fj.13-227264. Epub 2013 Apr 16.


[Thigh root reconstruction with a pedicled DIEP flap].

Gourari A, Quignon R, Tabareau-Delalande F, De Pinieux G, Rosset P, Pucheux J, Samimi M, Lorette G, Goga D, Zakine G.

Ann Chir Plast Esthet. 2014 Jun;59(3):212-4. doi: 10.1016/j.anplas.2013.01.002. Epub 2013 Feb 4. French.


Diagnostic value of investigating GNAS mutations in fibro-osseous lesions: a retrospective study of 91 cases of fibrous dysplasia and 40 other fibro-osseous lesions.

Tabareau-Delalande F, Collin C, Gomez-Brouchet A, Decouvelaere AV, Bouvier C, Larousserie F, Marie B, Delfour C, Aubert S, Rosset P, de Muret A, Pagès JC, de Pinieux G.

Mod Pathol. 2013 Jul;26(7):911-21. doi: 10.1038/modpathol.2012.223. Epub 2013 Feb 1.


Prognostic factors of extremity soft tissue sarcoma in adults. A single institutional analysis.

Atean I, Pointreau Y, Rosset P, Garaud P, De-Pinieux G, Calais G.

Cancer Radiother. 2012 Dec;16(8):661-6. doi: 10.1016/j.canrad.2012.05.021. Epub 2012 Nov 8.


[Telangiectatic osteosarcoma secondary to a liposclerosing myxofibrous tumor: a case report].

Illac C, Delisle MB, Bonnevialle P, Chiavassa-Gandois H, de Pinieux G, Gomez-Brouchet A.

Ann Pathol. 2012 Aug;32(4):259-62. doi: 10.1016/j.annpat.2012.06.003. Epub 2012 Jul 21. Review. French.


Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth.

Surdez D, Benetkiewicz M, Perrin V, Han ZY, Pierron G, Ballet S, Lamoureux F, Rédini F, Decouvelaere AV, Daudigeos-Dubus E, Geoerger B, de Pinieux G, Delattre O, Tirode F.

Cancer Res. 2012 Sep 1;72(17):4494-503. Epub 2012 Aug 28.


Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors.

Guyader C, Céraline J, Gravier E, Morin A, Michel S, Erdmann E, de Pinieux G, Cabon F, Bergerat JP, Poupon MF, Oudard S.

PLoS One. 2012;7(8):e42252. doi: 10.1371/journal.pone.0042252. Epub 2012 Aug 6.


[About a case of rhabdomyosarcoma with an aberrant expression of epithelial markers: a cause of misdiagnosis].

Cormier B, Arbion F, Rousselot C, Gaillardin L, de Pinieux G.

Ann Pathol. 2012 Jun;32(3):224-8. doi: 10.1016/j.annpat.2012.01.004. Epub 2012 May 16. French.


Treatment of early-onset Gorham syndrome with 8-year follow-up.

Maruani A, Thimon S, de Courtivron B, de Pinieux G, Baulieu F, Machet L, Lorette G.

Pediatr Dermatol. 2013 May-Jun;30(3):391-4. doi: 10.1111/j.1525-1470.2011.01712.x. Epub 2012 Mar 1.


[Place of the pathologist in the management of primary bone tumors (osteosarcoma and Ewing's family tumors after neoadjuvant treatment)].

Gomez-Brouchet A, Bouvier C, Decouvelaere AV, Larousserie F, Aubert S, Leroy X, Guinebretière JM, Coulomb A, Cassagnau E, de Muret A, Audard V, Marie B, de Pinieux G.

Ann Pathol. 2011 Dec;31(6):455-65. doi: 10.1016/j.annpat.2011.10.009. Epub 2011 Nov 29. Review. French.


Primary cutaneous Ewing sarcoma: a systematic review focused on treatment and outcome.

Delaplace M, Lhommet C, de Pinieux G, Vergier B, de Muret A, Machet L.

Br J Dermatol. 2012 Apr;166(4):721-6. doi: 10.1111/j.1365-2133.2011.10743.x. Epub 2012 Mar 5. Review.


The Bone Niche of Chondrosarcoma: A Sanctuary for Drug Resistance, Tumour Growth and also a Source of New Therapeutic Targets.

David E, Blanchard F, Heymann MF, De Pinieux G, Gouin F, Rédini F, Heymann D.

Sarcoma. 2011;2011:932451. doi: 10.1155/2011/932451. Epub 2011 May 22.


MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone.

Dujardin F, Binh MB, Bouvier C, Gomez-Brouchet A, Larousserie F, Muret Ad, Louis-Brennetot C, Aurias A, Coindre JM, Guillou L, Pedeutour F, Duval H, Collin C, de Pinieux G.

Mod Pathol. 2011 May;24(5):624-37. doi: 10.1038/modpathol.2010.229. Epub 2011 Feb 18.


Low-grade extraskeletal osteosarcoma of the chest wall: case report and review of literature.

Sabatier R, Bouvier C, de Pinieux G, Sarran A, Brenot-Rossi I, Pedeutour F, Chetaille B, Viens P, Weiller PJ, Bertucci F.

BMC Cancer. 2010 Nov 24;10:645. doi: 10.1186/1471-2407-10-645.


Galectin-1 is a powerful marker to distinguish chondroblastic osteosarcoma and conventional chondrosarcoma.

Gomez-Brouchet A, Mourcin F, Gourraud PA, Bouvier C, De Pinieux G, Le Guelec S, Brousset P, Delisle MB, Schiff C.

Hum Pathol. 2010 Sep;41(9):1220-30. doi: 10.1016/j.humpath.2009.10.028. Epub 2010 Apr 18.


Unexpected diagnosis for an adrenal tumor: synovial sarcoma.

Just PA, Tissier F, Silvera S, Dousset B, Ballet S, Delattre O, Vacher-Lavenu MC, Goldwasser F, Bertagna X, De Pinieux G.

Ann Diagn Pathol. 2010 Feb;14(1):56-9. doi: 10.1016/j.anndiagpath.2009.05.004. Epub 2009 Aug 8.


Preclinical assessment of cisplatin-based therapy versus docetaxel-based therapy on a panel of human non-small-cell lung cancer xenografts.

Némati F, Bras-Gonçalves R, Fontaine JJ, de Pinieux G, De Cremoux P, Chapelier A, Daniel C, Laurent-Puig P, Livartowski A, Judde JG, Bordier V, Poupon MF, Decaudin D.

Anticancer Drugs. 2009 Nov;20(10):932-40. doi: 10.1097/CAD.0b013e32833009cc.


[Black bone disease of the skull and facial bones].

Laure B, Petraud A, Sury F, Bayol JC, Marquet-Van Der Mee N, de Pinieux G, Goga D.

Rev Stomatol Chir Maxillofac. 2009 Nov;110(5):303-5. doi: 10.1016/j.stomax.2009.03.010. Epub 2009 Jul 10. French.


Primary neuroendocrine tumor of the sacrum: case report and review of the literature.

Dujardin F, Beaussart P, de Muret A, Rosset P, Waynberger E, Mulleman D, de Pinieux G.

Skeletal Radiol. 2009 Aug;38(8):819-23. doi: 10.1007/s00256-009-0693-y. Epub 2009 Apr 10. Review.


CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts.

Marangoni E, Lecomte N, Durand L, de Pinieux G, Decaudin D, Chomienne C, Smadja-Joffe F, Poupon MF.

Br J Cancer. 2009 Mar 24;100(6):918-22. doi: 10.1038/sj.bjc.6604953. Epub 2009 Feb 24.


Ezrin immunohistochemical expression in cartilaginous tumours: a useful tool for differential diagnosis between chondroblastic osteosarcoma and chondrosarcoma.

Salas S, de Pinieux G, Gomez-Brouchet A, Larrousserie F, Leroy X, Aubert S, Decouvelaere AV, Giorgi R, Fernandez C, Bouvier C.

Virchows Arch. 2009 Jan;454(1):81-7. doi: 10.1007/s00428-008-0692-8. Epub 2008 Dec 3.


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