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Miliary tuberculosis leading to acute respiratory distress syndrome: Clinical experience in pediatric intensive care.

Piastra M, Picconi E, Morena TC, Valentini P, Buonsenso D, Conti G, Antonelli M, Wolfler AM, Chidini G, Pons-Òdena M, De Pascale G; INTREPID group.

Pediatr Pulmonol. 2019 Sep 9. doi: 10.1002/ppul.24510. [Epub ahead of print]


Neutrophil CD64 automated analysis for the diagnosis of sepsis: have we lost another challenge?

Cutuli SL, De Pascale G.

Minerva Anestesiol. 2019 Sep;85(9):925-927. doi: 10.23736/S0375-9393.19.13797-2. Epub 2019 May 14. No abstract available.


Effects of Thyroid Hormone Treatment on Diaphragmatic Efficiency in Subjects With Nonthyroidal Illness Syndrome and on Ventilation.

Bello G, Spinazzola G, Giammatteo V, Montini L, De Pascale G, Bisanti A, Annetta MG, Troiani E, Bianchi A, Pontecorvi A, Pennisi MA, Conti G, Antonelli M.

Respir Care. 2019 Apr 23. pii: respcare.06770. doi: 10.4187/respcare.06770. [Epub ahead of print]


Biased Complement Diversity Selection for Effective Exploration of Chemical Space in Hit-Finding Campaigns.

Jansen JM, De Pascale G, Fong S, Lindvall M, Moser HE, Pfister K, Warne B, Wartchow C.

J Chem Inf Model. 2019 May 28;59(5):1709-1714. doi: 10.1021/acs.jcim.9b00048. Epub 2019 Apr 3.


Comparable Serum and Plasma 1,3-β-d-Glucan Values Obtained Using the Wako β-Glucan Test in Patients with Probable or Proven Fungal Diseases.

De Carolis E, Marchionni F, Torelli R, Posteraro P, De Pascale G, Carelli S, Sanguinetti M, Posteraro B.

J Clin Microbiol. 2019 Apr 26;57(5). pii: e00149-19. doi: 10.1128/JCM.00149-19. Print 2019 May. No abstract available.


Early nasal high-flow versus Venturi mask oxygen therapy after lung resection: a randomized trial.

Pennisi MA, Bello G, Congedo MT, Montini L, Nachira D, Ferretti GM, Meacci E, Gualtieri E, De Pascale G, Grieco DL, Margaritora S, Antonelli M.

Crit Care. 2019 Feb 28;23(1):68. doi: 10.1186/s13054-019-2361-5.


Risk factors for mortality and cost implications of complicated intra-abdominal infections in critically ill patients.

De Pascale G, Carelli S, Vallecoccia MS, Cutuli SL, Taccheri T, Montini L, Bello G, Spanu T, Tumbarello M, Cicchetti A, Urbina I, Oradei M, Marchetti M, Antonelli M.

J Crit Care. 2019 Apr;50:169-176. doi: 10.1016/j.jcrc.2018.12.001. Epub 2018 Dec 12.


Desirability of outcome ranking (DOOR) for comparing diagnostic tools and early therapeutic choices in patients with suspected candidemia.

Giacobbe DR, Signori A, Tumbarello M, Ungaro R, Sarteschi G, Furfaro E, Mikulska M, Sanguinetti M, Posteraro B, Losito AR, De Pascale G, Del Bono V, Viscoli C.

Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):413-417. doi: 10.1007/s10096-018-3441-1. Epub 2018 Nov 30.


Steroids and severe pneumonia. Ready for the winter? Discussion on "Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study".

De Pascale G, Bello G, Dell'Anna AM, Montini L, Antonelli M, Moreno G, Rodriguez A, Martin-Loeches I.

Intensive Care Med. 2018 Dec;44(12):2319-2320. doi: 10.1007/s00134-018-5414-3. Epub 2018 Oct 24. No abstract available.


Diagnosis of nonventilated hospital-acquired pneumonia: how much do we know?

Ranzani OT, De Pascale G, Park M.

Curr Opin Crit Care. 2018 Oct;24(5):339-346. doi: 10.1097/MCC.0000000000000525. Review.


Efficacy of Ceftazidime-Avibactam Salvage Therapy in Patients With Infections Caused by Klebsiella pneumoniae Carbapenemase-producing K. pneumoniae.

Tumbarello M, Trecarichi EM, Corona A, De Rosa FG, Bassetti M, Mussini C, Menichetti F, Viscoli C, Campoli C, Venditti M, De Gasperi A, Mularoni A, Tascini C, Parruti G, Pallotto C, Sica S, Concia E, Cultrera R, De Pascale G, Capone A, Antinori S, Corcione S, Righi E, Losito AR, Digaetano M, Amadori F, Giacobbe DR, Ceccarelli G, Mazza E, Raffaelli F, Spanu T, Cauda R, Viale P.

Clin Infect Dis. 2019 Jan 18;68(3):355-364. doi: 10.1093/cid/ciy492.


Improving the care for elective surgical patients: post-operative ICU admission and outcome.

Cutuli SL, Carelli S, De Pascale G, Antonelli M.

J Thorac Dis. 2018 Apr;10(Suppl 9):S1047-S1049. doi: 10.21037/jtd.2018.04.64. No abstract available.


T2Bacteria magnetic resonance assay for the rapid detection of ESKAPEc pathogens directly in whole blood.

De Angelis G, Posteraro B, De Carolis E, Menchinelli G, Franceschi F, Tumbarello M, De Pascale G, Spanu T, Sanguinetti M.

J Antimicrob Chemother. 2018 Mar 1;73(suppl_4):iv20-iv26. doi: 10.1093/jac/dky049.


A pathway-directed positive growth restoration assay to facilitate the discovery of lipid A and fatty acid biosynthesis inhibitors in Acinetobacter baumannii.

Richie DL, Wang L, Chan H, De Pascale G, Six DA, Wei JR, Dean CR.

PLoS One. 2018 Mar 5;13(3):e0193851. doi: 10.1371/journal.pone.0193851. eCollection 2018.


Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project.

De Pascale G, Ranzani OT, Nseir S, Chastre J, Welte T, Antonelli M, Navalesi P, Garofalo E, Bruni A, Coelho LM, Skoczynski S, Longhini F, Taccone FS, Grimaldi D, Salzer HJF, Lange C, Froes F, Artigas A, Díaz E, Vallés J, Rodríguez A, Panigada M, Comellini V, Fasano L, Soave PM, Spinazzola G, Luyt CE, Alvarez-Lerma F, Marin J, Masclans JR, Chiumello D, Pezzi A, Schultz M, Mohamed H, Van Der Eerden M, Hoek RAS, Gommers DAMPJ, Pasquale MD, Civljak R, Kutleša M, Bassetti M, Dimopoulos G, Nava S, Rios F, Zampieri FG, Povoa P, Bos LD, Aliberti S, Torres A, Martín-Loeches I.

ERJ Open Res. 2017 Nov 17;3(4). pii: 00092-2017. doi: 10.1183/23120541.00092-2017. eCollection 2017 Oct.


Levosimendan in Cardiac Surgery.

Dell'Anna AM, De Pascale G, Antonelli M.

N Engl J Med. 2017 Nov 9;377(19):1899. doi: 10.1056/NEJMc1711938. No abstract available.


Combined use of serum (1,3)-β-D-glucan and procalcitonin for the early differential diagnosis between candidaemia and bacteraemia in intensive care units.

Giacobbe DR, Mikulska M, Tumbarello M, Furfaro E, Spadaro M, Losito AR, Mesini A, De Pascale G, Marchese A, Bruzzone M, Pelosi P, Mussap M, Molin A, Antonelli M, Posteraro B, Sanguinetti M, Viscoli C, Del Bono V; ISGRI-SITA (Italian Study Group on Resistant Infections of the Società Italiana Terapia Antinfettiva).

Crit Care. 2017 Jul 10;21(1):176. doi: 10.1186/s13054-017-1763-5.


Double carbapenem as a rescue strategy for the treatment of severe carbapenemase-producing Klebsiella pneumoniae infections: a two-center, matched case-control study.

De Pascale G, Martucci G, Montini L, Panarello G, Cutuli SL, Di Carlo D, Di Gravio V, Di Stefano R, Capitanio G, Vallecoccia MS, Polidori P, Spanu T, Arcadipane A, Antonelli M.

Crit Care. 2017 Jul 5;21(1):173. doi: 10.1186/s13054-017-1769-z.


CO2 driven endotracheal tube cuff control in critically ill patients: A randomized controlled study.

De Pascale G, Pennisi MA, Vallecoccia MS, Bello G, Maviglia R, Montini L, Di Gravio V, Cutuli SL, Conti G, Antonelli M.

PLoS One. 2017 May 11;12(5):e0175476. doi: 10.1371/journal.pone.0175476. eCollection 2017.


Comparison of stroke volume measurement between non-invasive bioreactance and esophageal Doppler in patients undergoing major abdominal-pelvic surgery.

De Pascale G, Singer M, Brealey D.

J Anesth. 2017 Aug;31(4):545-551. doi: 10.1007/s00540-017-2351-1. Epub 2017 Apr 8.


Lice, rodents, and many hopes: a rare disease in a young refugee.

Cutuli SL, De Pascale G, Spanu T, Dell'Anna AM, Bocci MG, Pallavicini F, Mancini F, Ciervo A, Antonelli M.

Crit Care. 2017 Apr 3;21(1):81. doi: 10.1186/s13054-017-1666-5. No abstract available.


Veno-venous extra-corporeal membrane oxygenation: pay attention to bloodstream infections!

DE Pascale G, Cutuli SL, Antonelli M.

Minerva Anestesiol. 2017 May;83(5):440-442. doi: 10.23736/S0375-9393.17.12005-5. Epub 2017 Mar 22. No abstract available.


'σήψις' yesterday, sepsis nowadays: what's changing?

Cutuli SL, De Pascale G, Antonelli M.

J Thorac Dis. 2017 Feb;9(2):E166-E167. doi: 10.21037/jtd.2017.02.43. No abstract available.


A Common Platform for Antibiotic Dereplication and Adjuvant Discovery.

Cox G, Sieron A, King AM, De Pascale G, Pawlowski AC, Koteva K, Wright GD.

Cell Chem Biol. 2017 Jan 19;24(1):98-109. doi: 10.1016/j.chembiol.2016.11.011. Epub 2016 Dec 22.


Noninvasive Ventilation.

Bello G, De Pascale G, Antonelli M.

Clin Chest Med. 2016 Dec;37(4):711-721. doi: 10.1016/j.ccm.2016.07.011. Epub 2016 Sep 10. Review.


Prognostic value of the reactive oxygen species in severe sepsis and septic shock patients: a pilot study.

Montini L, DE Sole P, Pennisi MA, Rossi C, Scatena R, DE Pascale G, Bello G, Cutuli SL, Antonelli M.

Minerva Anestesiol. 2016 Dec;82(12):1306-1313. Epub 2016 Sep 9.


(1,3)-β-d-Glucan-based antifungal treatment in critically ill adults at high risk of candidaemia: an observational study.

Posteraro B, Tumbarello M, De Pascale G, Liberto E, Vallecoccia MS, De Carolis E, Di Gravio V, Trecarichi EM, Sanguinetti M, Antonelli M.

J Antimicrob Chemother. 2016 Aug;71(8):2262-9. doi: 10.1093/jac/dkw112. Epub 2016 Apr 28.


Risk factors for KPC-producing Klebsiella pneumoniae VAP: keep an eye on previous therapies!

DE Pascale G, Antonelli M.

Minerva Anestesiol. 2016 Jun;82(6):616-8. Epub 2016 Mar 31. No abstract available.


Clinical impact of pulmonary sampling site in the diagnosis of ventilator-associated pneumonia: A prospective study using bronchoscopic bronchoalveolar lavage.

Bello G, Pennisi MA, Di Muzio F, De Pascale G, Montini L, Maviglia R, Mercurio G, Spanu T, Antonelli M.

J Crit Care. 2016 Jun;33:151-7. doi: 10.1016/j.jcrc.2016.02.016. Epub 2016 Mar 3.


Clinical and microbiological outcome in septic patients with extremely low 25-hydroxyvitamin D levels at initiation of critical care.

De Pascale G, Vallecoccia MS, Schiattarella A, Di Gravio V, Cutuli SL, Bello G, Montini L, Pennisi MA, Spanu T, Zuppi C, Quraishi SA, Antonelli M.

Clin Microbiol Infect. 2016 May;22(5):456.e7-456.e13. doi: 10.1016/j.cmi.2015.12.015. Epub 2015 Dec 23.


Evaluation of the Infection-Related Ventilator-Associated Events Algorithm for Ventilator-Associated Pneumonia Surveillance in a Trauma Population.

Piriyapatsom A, Lin H, Pirrone M, De Pascale G, Corona De Lapuerta J, Bittner EA, Schmidt UH, De Moya M, Berra L.

Respir Care. 2016 Mar;61(3):269-76. doi: 10.4187/respcare.04280. Epub 2015 Nov 10.


Appropriate Tigecycline Use for Extensively Drug-Resistant Infections: The Standard Dose May Not Be Enough!

De Pascale G, Antonelli M.

Crit Care Med. 2015 Nov;43(11):e533-4. doi: 10.1097/CCM.0000000000001230. No abstract available.


Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical space.

Ross AG, Benton BM, Chin D, De Pascale G, Fuller J, Leeds JA, Reck F, Richie DL, Vo J, LaMarche MJ.

Bioorg Med Chem Lett. 2015 Sep 1;25(17):3468-75. doi: 10.1016/j.bmcl.2015.07.010. Epub 2015 Jul 9.


Fungal infections in the ICU: advances in treatment and diagnosis.

De Pascale G, Tumbarello M.

Curr Opin Crit Care. 2015 Oct;21(5):421-9. doi: 10.1097/MCC.0000000000000230. Review.


Effect of Cholecalciferol Supplementation on Vitamin D Status and Cathelicidin Levels in Sepsis: A Randomized, Placebo-Controlled Trial.

Quraishi SA, De Pascale G, Needleman JS, Nakazawa H, Kaneki M, Bajwa EK, Camargo CA Jr, Bhan I.

Crit Care Med. 2015 Sep;43(9):1928-37. doi: 10.1097/CCM.0000000000001148.


Dose of colistin: a work in progress?

Rocco M, Montini L, De Pascale G, Antonelli M.

Crit Care. 2015 Feb 16;19:65. doi: 10.1186/s13054-015-0743-x. No abstract available.


Closed vs open systems: when should short peripheral intravenous catheters be the first choice?

Vallecoccia MS, De Pascale G, Taraschi C, De Angelis Durante R, Dolcetti L, Pittiruti M, Scoppettuolo G.

J Hosp Infect. 2015 Jan;89(1):72-3. doi: 10.1016/j.jhin.2014.09.010. Epub 2014 Oct 19. No abstract available.


Linezolid plasma and intrapulmonary concentrations in critically ill obese patients with ventilator-associated pneumonia: intermittent vs continuous administration.

De Pascale G, Fortuna S, Tumbarello M, Cutuli SL, Vallecoccia M, Spanu T, Bello G, Montini L, Pennisi MA, Navarra P, Antonelli M.

Intensive Care Med. 2015 Jan;41(1):103-10. doi: 10.1007/s00134-014-3550-y. Epub 2014 Nov 21.


Endotracheal tubes cuff pressure control: does the CO2 matter?

Vallecoccia MS, De Pascale G, Cutuli SL, Di Gravio V, Pennisi MA, Antonelli M.

Minerva Anestesiol. 2015 Mar;81(3):352-3. Epub 2014 Nov 6. No abstract available.


Influenza-associated critical illness: estimating the burden and the burden of estimation.

De Pascale G, Bittner EA.

Crit Care Med. 2014 Nov;42(11):2441-2. doi: 10.1097/CCM.0000000000000589. No abstract available.


How to manage aspergillosis in non-neutropenic intensive care unit patients.

Bassetti M, Righi E, De Pascale G, De Gaudio R, Giarratano A, Mazzei T, Morace G, Petrosillo N, Stefani S, Antonelli M.

Crit Care. 2014 Jul 25;18(4):458. doi: 10.1186/s13054-014-0458-4. Review.


Vitamin D status in critically ill patients: the evidence is now bioavailable!

De Pascale G, Quraishi SA.

Crit Care. 2014 Jul 7;18(4):449. doi: 10.1186/cc13975. No abstract available.


Candida colonization of respiratory tract: to treat or not to treat, will we ever get an answer?

De Pascale G, Antonelli M.

Intensive Care Med. 2014 Sep;40(9):1381-4. doi: 10.1007/s00134-014-3364-y. Epub 2014 Jul 1. No abstract available.


Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.

King AM, Reid-Yu SA, Wang W, King DT, De Pascale G, Strynadka NC, Walsh TR, Coombes BK, Wright GD.

Nature. 2014 Jun 26;510(7506):503-6. doi: 10.1038/nature13445.


High dose tigecycline in critically ill patients with severe infections due to multidrug-resistant bacteria.

De Pascale G, Montini L, Pennisi M, Bernini V, Maviglia R, Bello G, Spanu T, Tumbarello M, Antonelli M.

Crit Care. 2014 May 5;18(3):R90. doi: 10.1186/cc13858.


A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality.

Bassetti M, Righi E, Ansaldi F, Merelli M, Trucchi C, De Pascale G, Diaz-Martin A, Luzzati R, Rosin C, Lagunes L, Trecarichi EM, Sanguinetti M, Posteraro B, Garnacho-Montero J, Sartor A, Rello J, Rocca GD, Antonelli M, Tumbarello M.

Intensive Care Med. 2014 Jun;40(6):839-45. doi: 10.1007/s00134-014-3310-z. Epub 2014 May 8. Erratum in: Intensive Care Med. 2014 Aug;40(8):1186. Cecilia, Trucchi [corrected to Trucchi, Cecilia].



Tumbarello M, De Pascale G, Antonelli M.

Chest. 2014 Apr;145(4):927. doi: 10.1378/chest.14-0098. No abstract available.


Clinical experience of colistin-glycopeptide combination in critically ill patients infected with Gram-negative bacteria.

Petrosillo N, Giannella M, Antonelli M, Antonini M, Barsic B, Belancic L, Inkaya A C, De Pascale G, Grilli E, Tumbarello M, Akova M.

Antimicrob Agents Chemother. 2014;58(2):851-8. doi: 10.1128/AAC.00871-13. Epub 2013 Nov 25.


The role of mannose-binding lectin in severe sepsis and septic shock.

De Pascale G, Cutuli SL, Pennisi MA, Antonelli M.

Mediators Inflamm. 2013;2013:625803. doi: 10.1155/2013/625803. Epub 2013 Oct 2. Review.


Effect of aerosolized colistin as adjunctive treatment on the outcomes of microbiologically documented ventilator-associated pneumonia caused by colistin-only susceptible gram-negative bacteria.

Tumbarello M, De Pascale G, Trecarichi EM, De Martino S, Bello G, Maviglia R, Spanu T, Antonelli M.

Chest. 2013 Dec;144(6):1768-1775. doi: 10.1378/chest.13-1018.


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