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Items: 46


In vivo modeling of human neuron dynamics and Down syndrome.

Real R, Peter M, Trabalza A, Khan S, Smith MA, Dopp J, Barnes SJ, Momoh A, Strano A, Volpi E, Knott G, Livesey FJ, De Paola V.

Science. 2018 Nov 16;362(6416). pii: eaau1810. doi: 10.1126/science.aau1810. Epub 2018 Oct 11.


The effects of haloperidol on microglial morphology and translocator protein levels: An in vivo study in rats using an automated cell evaluation pipeline.

Bloomfield PS, Bonsall D, Wells L, Dormann D, Howes O, De Paola V.

J Psychopharmacol. 2018 Nov;32(11):1264-1272. doi: 10.1177/0269881118788830. Epub 2018 Aug 21.


The effects of aging on neuropil structure in mouse somatosensory cortex-A 3D electron microscopy analysis of layer 1.

Calì C, Wawrzyniak M, Becker C, Maco B, Cantoni M, Jorstad A, Nigro B, Grillo F, De Paola V, Fua P, Knott GW.

PLoS One. 2018 Jul 2;13(7):e0198131. doi: 10.1371/journal.pone.0198131. eCollection 2018.


In Vivo Imaging of CNS Injury and Disease.

Akassoglou K, Merlini M, Rafalski VA, Real R, Liang L, Jin Y, Dougherty SE, De Paola V, Linden DJ, Misgeld T, Zheng B.

J Neurosci. 2017 Nov 8;37(45):10808-10816. doi: 10.1523/JNEUROSCI.1826-17.2017. Review.


Detection of axonal synapses in 3D two-photon images.

Bass C, Helkkula P, De Paola V, Clopath C, Bharath AA.

PLoS One. 2017 Sep 5;12(9):e0183309. doi: 10.1371/journal.pone.0183309. eCollection 2017.


EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.

Krusche B, Ottone C, Clements MP, Johnstone ER, Goetsch K, Lieven H, Mota SG, Singh P, Khadayate S, Ashraf A, Davies T, Pollard SM, De Paola V, Roncaroli F, Martinez-Torrecuadrada J, Bertone P, Parrinello S.

Elife. 2016 Jun 28;5. pii: e14845. doi: 10.7554/eLife.14845.


Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study.

Bloomfield PS, Selvaraj S, Veronese M, Rizzo G, Bertoldo A, Owen DR, Bloomfield MA, Bonoldi I, Kalk N, Turkheimer F, McGuire P, de Paola V, Howes OD.

Am J Psychiatry. 2016 Jan;173(1):44-52. doi: 10.1176/appi.ajp.2015.14101358. Epub 2015 Oct 16. Erratum in: Am J Psychiatry. 2017 Apr 1;174(4):402.


Laser-Mediated Microlesions in Mouse Neocortex to Investigate Neuronal Degeneration and Regeneration.

Jackson J, Canty AJ, Huang L, De Paola V.

Curr Protoc Neurosci. 2015 Oct 1;73:2.24.1-2.24.17. doi: 10.1002/0471142301.ns0224s73.


Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease.

Pienaar IS, Gartside SE, Sharma P, De Paola V, Gretenkord S, Withers D, Elson JL, Dexter DT.

Mol Neurodegener. 2015 Sep 23;10:47. doi: 10.1186/s13024-015-0044-5.


Removing synaptic brakes on learning.

Grillo FW, West L, De Paola V.

Nat Neurosci. 2015 Aug;18(8):1062-4. doi: 10.1038/nn.4073. No abstract available.


EPBscore: a Novel Method for Computer-Assisted Analysis of Axonal Structure and Dynamics.

Song S, Grillo FW, Xi J, Ferretti V, Gao G, De Paola V.

Neuroinformatics. 2016 Jan;14(1):121-7. doi: 10.1007/s12021-015-9274-5. No abstract available.


Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.

Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PLM, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E.

Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031.


In-vivo single neuron axotomy triggers axon regeneration to restore synaptic density in specific cortical circuits.

Canty AJ, Huang L, Jackson JS, Little GE, Knott G, Maco B, De Paola V.

Nat Commun. 2013;4:2038. doi: 10.1038/ncomms3038.


Synaptic elimination and protection after minimal injury depend on cell type and their prelesion structural dynamics in the adult cerebral cortex.

Canty AJ, Teles-Grilo Ruivo LM, Nesarajah C, Song S, Jackson JS, Little GE, De Paola V.

J Neurosci. 2013 Jun 19;33(25):10374-83. doi: 10.1523/JNEUROSCI.0254-13.2013.


In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex.

Allegra Mascaro AL, Cesare P, Sacconi L, Grasselli G, Mandolesi G, Maco B, Knott GW, Huang L, De Paola V, Strata P, Pavone FS.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10824-9. doi: 10.1073/pnas.1219256110. Epub 2013 Jun 10.


Increased axonal bouton dynamics in the aging mouse cortex.

Grillo FW, Song S, Teles-Grilo Ruivo LM, Huang L, Gao G, Knott GW, Maco B, Ferretti V, Thompson D, Little GE, De Paola V.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1514-23. doi: 10.1073/pnas.1218731110. Epub 2013 Mar 29.


Imaging neocortical neurons through a chronic cranial window.

Holtmaat A, de Paola V, Wilbrecht L, Trachtenberg JT, Svoboda K, Portera-Cailliau C.

Cold Spring Harb Protoc. 2012 Jun 1;2012(6):694-701. doi: 10.1101/pdb.prot069617.


Activin induces cortical interneuron identity and differentiation in embryonic stem cell-derived telencephalic neural precursors.

Cambray S, Arber C, Little G, Dougalis AG, de Paola V, Ungless MA, Li M, Rodríguez TA.

Nat Commun. 2012 May 15;3:841. doi: 10.1038/ncomms1817.


Axonal reconstructions going live.

Canty AJ, De Paola V.

Neuroinformatics. 2011 Sep;9(2-3):129-31. doi: 10.1007/s12021-011-9112-3. No abstract available.


The DIADEM data sets: representative light microscopy images of neuronal morphology to advance automation of digital reconstructions.

Brown KM, Barrionuevo G, Canty AJ, De Paola V, Hirsch JA, Jefferis GS, Lu J, Snippe M, Sugihara I, Ascoli GA.

Neuroinformatics. 2011 Sep;9(2-3):143-57. doi: 10.1007/s12021-010-9095-5. Review.


Lasofoxifene: Evidence of its therapeutic value in osteoporosis.

Gennari L, Merlotti D, De Paola V, Nuti R.

Core Evid. 2010 Jun 15;4:113-29.


The use of intravenous aminobisphosphonates for the treatment of Paget's disease of bone.

Gennari L, Merlotti D, Mossetti G, Rendina D, De Paola V, Martini G, Nuti R.

Mini Rev Med Chem. 2009 Aug;9(9):1052-63. Review.


Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window.

Holtmaat A, Bonhoeffer T, Chow DK, Chuckowree J, De Paola V, Hofer SB, Hübener M, Keck T, Knott G, Lee WC, Mostany R, Mrsic-Flogel TD, Nedivi E, Portera-Cailliau C, Svoboda K, Trachtenberg JT, Wilbrecht L.

Nat Protoc. 2009;4(8):1128-44. doi: 10.1038/nprot.2009.89. Epub 2009 Jul 16.


Bazedoxifene for the prevention of postmenopausal osteoporosis.

Gennari L, Merlotti D, De Paola V, Martini G, Nuti R.

Ther Clin Risk Manag. 2008 Dec;4(6):1229-42.


Update on the pharmacogenetics of the vitamin D receptor and osteoporosis.

Gennari L, Merlotti D, De Paola V, Martini G, Nuti R.

Pharmacogenomics. 2009 Mar;10(3):417-33. doi: 10.2217/14622416.10.3.417. Review.


Vitamin D receptor gene polymorphisms predict acquired resistance to clodronate treatment in patients with Paget's disease of bone.

Mossetti G, Gennari L, Rendina D, De Filippo G, Merlotti D, De Paola V, Fusco P, Esposito T, Gianfrancesco F, Martini G, Nuti R, Strazzullo P.

Calcif Tissue Int. 2008 Dec;83(6):414-24. doi: 10.1007/s00223-008-9193-7. Epub 2008 Nov 20.


Dendritic spine morphology determines membrane-associated protein exchange between dendritic shafts and spine heads.

Hugel S, Abegg M, de Paola V, Caroni P, Gähwiler BH, McKinney RA.

Cereb Cortex. 2009 Mar;19(3):697-702. doi: 10.1093/cercor/bhn118. Epub 2008 Jul 24.


Imaging of experience-dependent structural plasticity in the mouse neocortex in vivo.

Holtmaat A, De Paola V, Wilbrecht L, Knott GW.

Behav Brain Res. 2008 Sep 1;192(1):20-5. doi: 10.1016/j.bbr.2008.04.005. Epub 2008 Apr 18.


The effects of zoledronic acid on serum lipids in multiple myeloma patients.

Gozzetti A, Gennari L, Merlotti D, Salvadori S, De Paola V, Avanzati A, Franci B, Marchini E, Tozzi M, Campagna MS, Nuti R, Lauria F, Martini G.

Calcif Tissue Int. 2008 Apr;82(4):258-62. doi: 10.1007/s00223-008-9123-8. Epub 2008 Apr 17.


The effects of recombinant TSH on bone turnover markers and serum osteoprotegerin and RANKL levels.

Martini G, Gennari L, De Paola V, Pilli T, Salvadori S, Merlotti D, Valleggi F, Campagna S, Franci B, Avanzati A, Nuti R, Pacini F.

Thyroid. 2008 Apr;18(4):455-60. doi: 10.1089/thy.2007.0166.


Bone metabolism in men: role of aromatase activity.

Nuti R, Martini G, Merlotti D, De Paola V, Valleggi F, Gennari L.

J Endocrinol Invest. 2007;30(6 Suppl):18-23. Review.


Comparison of different intravenous bisphosphonate regimens for Paget's disease of bone.

Merlotti D, Gennari L, Martini G, Valleggi F, De Paola V, Avanzati A, Nuti R.

J Bone Miner Res. 2007 Oct;22(10):1510-7.


Steroid hormone receptor gene polymorphisms and osteoporosis: a pharmacogenomic review.

Gennari L, De Paola V, Merlotti D, Martini G, Nuti R.

Expert Opin Pharmacother. 2007 Apr;8(5):537-53. Review.


Serum OPG and RANKL levels before and after intravenous bisphosphonate treatment in Paget's disease of bone.

Martini G, Gennari L, Merlotti D, Salvadori S, Franci MB, Campagna S, Avanzati A, De Paola V, Valleggi F, Nuti R.

Bone. 2007 Feb;40(2):457-63. Epub 2006 Sep 18.


Professional sport activity and micronutrients: effects on bone mass.

Nuti R, Martini G, Merlotti D, Valleggi F, De Paola V, Gennari L.

J Endocrinol Invest. 2005;28(10 Suppl):52-60. Review.


Cell type-specific structural plasticity of axonal branches and boutons in the adult neocortex.

De Paola V, Holtmaat A, Knott G, Song S, Wilbrecht L, Caroni P, Svoboda K.

Neuron. 2006 Mar 16;49(6):861-75.


Relation of plasma brain natriuretic peptide levels in non-ST-elevation coronary disease and preserved systolic function to number of narrowed coronary arteries.

Palazzuoli A, Gennari L, Calabria P, Quatrini I, Vecchiato L, De Paola V, Campagna MS, Palazzuoli V, Nuti R.

Am J Cardiol. 2005 Dec 15;96(12):1705-10. Epub 2005 Nov 2.


Effects of carvedilol on left ventricular diastolic function and chamber volumes in advanced heart failure.

Palazzuoli A, Quatrini I, Vecchiato L, Scali C, De Paola V, Iovine F, Martini G, Nuti R.

Minerva Cardioangiol. 2005 Aug;53(4):321-8.


Prevalence of Paget's disease of bone in Italy.

Gennari L, Di Stefano M, Merlotti D, Giordano N, Martini G, Tamone C, Zatteri R, De Lucchi R, Baldi C, Vattimo A, Capoccia S, Burroni L, Geraci S, De Paola V, Calabrò A, Avanzati A, Isaia G, Nuti R.

J Bone Miner Res. 2005 Oct;20(10):1845-50. Epub 2005 May 31.


Diverse modes of axon elaboration in the developing neocortex.

Portera-Cailliau C, Weimer RM, De Paola V, Caroni P, Svoboda K.

PLoS Biol. 2005 Aug;3(8):e272. Epub 2005 Jul 26.


Characteristics and familial aggregation of Paget's disease of bone in Italy.

Merlotti D, Gennari L, Galli B, Martini G, Calabrò A, De Paola V, Ceccarelli E, Nardi P, Avanzati A, Nuti R.

J Bone Miner Res. 2005 Aug;20(8):1356-64. Epub 2005 Mar 28.


Glutamate induces the rapid formation of spine head protrusions in hippocampal slice cultures.

Richards DA, Mateos JM, Hugel S, de Paola V, Caroni P, Gähwiler BH, McKinney RA.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6166-71. Epub 2005 Apr 14.


Estrogen receptor gene polymorphisms and the genetics of osteoporosis: a HuGE review.

Gennari L, Merlotti D, De Paola V, Calabrò A, Becherini L, Martini G, Nuti R.

Am J Epidemiol. 2005 Feb 15;161(4):307-20. Review.


AMPA-receptor activation regulates the diffusion of a membrane marker in parallel with dendritic spine motility in the mouse hippocampus.

Richards DA, De Paola V, Caroni P, Gähwiler BH, McKinney RA.

J Physiol. 2004 Jul 15;558(Pt 2):503-12. Epub 2004 May 28.


AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

De Paola V, Arber S, Caroni P.

Nat Neurosci. 2003 May;6(5):491-500.


ETS gene Pea3 controls the central position and terminal arborization of specific motor neuron pools.

Livet J, Sigrist M, Stroebel S, De Paola V, Price SR, Henderson CE, Jessell TM, Arber S.

Neuron. 2002 Aug 29;35(5):877-92.

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