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Items: 43

1.

miRNA-135b Contributes to Triple Negative Breast Cancer Molecular Heterogeneity: Different Expression Profile in Basal-like Versus non-Basal-like Phenotypes.

Uva P, Cossu-Rocca P, Loi F, Pira G, Murgia L, Orrù S, Floris M, Muroni MR, Sanges F, Carru C, Angius A, De Miglio MR.

Int J Med Sci. 2018 Mar 9;15(6):536-548. doi: 10.7150/ijms.23402. eCollection 2018.

2.

Colorectal cancer early methylation alterations affect the crosstalk between cell and surrounding environment, tracing a biomarker signature specific for this tumor.

Fadda A, Gentilini D, Moi L, Barault L, Leoni VP, Sulas P, Zorcolo L, Restivo A, Cabras F, Fortunato F, Zavattari C, Varesco L, Gismondi V, De Miglio MR, Scanu AM, Colombi F, Lombardi P, Sarotto I, Loi E, Leone F, Giordano S, Di Nicolantonio F, Columbano A, Zavattari P.

Int J Cancer. 2018 Aug 15;143(4):907-920. doi: 10.1002/ijc.31380. Epub 2018 Apr 6.

PMID:
29542109
3.

Clinical and pathological factors influencing survival in a large cohort of triple-negative breast cancer patients.

Urru SAM, Gallus S, Bosetti C, Moi T, Medda R, Sollai E, Murgia A, Sanges F, Pira G, Manca A, Palmas D, Floris M, Asunis AM, Atzori F, Carru C, D'Incalci M, Ghiani M, Marras V, Onnis D, Santona MC, Sarobba G, Valle E, Canu L, Cossu S, Bulfone A, Rocca PC, De Miglio MR, Orrù S.

BMC Cancer. 2018 Jan 8;18(1):56. doi: 10.1186/s12885-017-3969-y.

4.

EGFR kinase-dependent and kinase-independent roles in clear cell renal cell carcinoma.

Cossu-Rocca P, Muroni MR, Sanges F, Sotgiu G, Asunis A, Tanca L, Onnis D, Pira G, Manca A, Dore S, Uras MG, Ena S, De Miglio MR.

Am J Cancer Res. 2015 Dec 15;6(1):71-83. eCollection 2016.

5.

Analysis of PIK3CA Mutations and Activation Pathways in Triple Negative Breast Cancer.

Cossu-Rocca P, Orrù S, Muroni MR, Sanges F, Sotgiu G, Ena S, Pira G, Murgia L, Manca A, Uras MG, Sarobba MG, Urru S, De Miglio MR.

PLoS One. 2015 Nov 5;10(11):e0141763. doi: 10.1371/journal.pone.0141763. eCollection 2015.

6.

Investigation of HER2 expression in canine mammary tumors by antibody-based, transcriptomic and mass spectrometry analysis: is the dog a suitable animal model for human breast cancer?

Burrai GP, Tanca A, De Miglio MR, Abbondio M, Pisanu S, Polinas M, Pirino S, Mohammed SI, Uzzau S, Addis MF, Antuofermo E.

Tumour Biol. 2015 Nov;36(11):9083-91. doi: 10.1007/s13277-015-3661-2. Epub 2015 Jun 19.

PMID:
26088453
7.

HPV infection and triple-negative breast cancers: an Italian case-control study.

Piana AF, Sotgiu G, Muroni MR, Cossu-Rocca P, Castiglia P, De Miglio MR.

Virol J. 2014 Nov 21;11:190. doi: 10.1186/s12985-014-0190-3.

8.

Analysis of epidermal growth factor receptor (EGFR) status in endometrial stromal sarcoma.

Capobianco G, Pili F, Contini M, De Miglio MR, Marras V, Santeufemia DA, Cherchi C, Dessole M, Cherchi PL, Cossu-Rocca P.

Eur J Gynaecol Oncol. 2012;33(6):629-32.

PMID:
23327060
9.

Tyrosine kinase receptor status in endometrial stromal sarcoma: an immunohistochemical and genetic-molecular analysis.

Cossu-Rocca P, Contini M, Uras MG, Muroni MR, Pili F, Carru C, Bosincu L, Massarelli G, Nogales FF, De Miglio MR.

Int J Gynecol Pathol. 2012 Nov;31(6):570-9. doi: 10.1097/PGP.0b013e31824fe289.

PMID:
23018215
10.

Evaluation of methylation degree from formalin-fixed paraffin-embedded DNA extract by field-amplified sample injection capillary electrophoresis with UV detection.

Zinellu A, Sotgia S, De Murtas V, Cossu-Rocca P, De Miglio MR, Muroni MR, Mura A, Uras MG, Contini M, Deiana L, Carru C.

Anal Bioanal Chem. 2011 Jan;399(3):1181-6. doi: 10.1007/s00216-010-4417-x. Epub 2010 Nov 21.

PMID:
21104070
11.

High sensitivity of reverse-hybridization methodology in the detection of KRAS mutations from formalin-fixed paraffin-embedded colorectal cancer samples.

De Miglio MR, Mura A, Uras MG, Manca A, Contini M, Murgia L, Zinellu A, Sotgia S, Carru C, Massarelli G, Cossu-Rocca P.

Diagn Mol Pathol. 2010 Dec;19(4):201-8. doi: 10.1097/PDM.0b013e3181db67d5.

PMID:
21052001
12.

Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC.

Calvisi DF, Pinna F, Ladu S, Pellegrino R, Simile MM, Frau M, De Miglio MR, Tomasi ML, Sanna V, Muroni MR, Feo F, Pascale RM.

Gut. 2009 May;58(5):679-87. doi: 10.1136/gut.2008.152652. Epub 2009 Jan 9.

PMID:
19136513
13.

Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control.

Calvisi DF, Pinna F, Pellegrino R, Sanna V, Sini M, Daino L, Simile MM, De Miglio MR, Frau M, Tomasi ML, Seddaiu MA, Muroni MR, Feo F, Pascale RM.

Int J Cancer. 2008 Nov 1;123(9):2057-64. doi: 10.1002/ijc.23720.

14.

Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.

Calvisi DF, Pinna F, Ladu S, Pellegrino R, Muroni MR, Simile MM, Frau M, Tomasi ML, De Miglio MR, Seddaiu MA, Daino L, Sanna V, Feo F, Pascale RM.

Carcinogenesis. 2008 Aug;29(8):1639-47. doi: 10.1093/carcin/bgn155. Epub 2008 Jun 25.

PMID:
18579559
15.

Dual-specificity phosphatase 1 ubiquitination in extracellular signal-regulated kinase-mediated control of growth in human hepatocellular carcinoma.

Calvisi DF, Pinna F, Meloni F, Ladu S, Pellegrino R, Sini M, Daino L, Simile MM, De Miglio MR, Virdis P, Frau M, Tomasi ML, Seddaiu MA, Muroni MR, Feo F, Pascale RM.

Cancer Res. 2008 Jun 1;68(11):4192-200. doi: 10.1158/0008-5472.CAN-07-6157.

16.

Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.

Calvisi DF, Simile MM, Ladu S, Pellegrino R, De Murtas V, Pinna F, Tomasi ML, Frau M, Virdis P, De Miglio MR, Muroni MR, Pascale RM, Feo F.

Int J Cancer. 2007 Dec 1;121(11):2410-20.

17.

Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/beta-catenin pathway and progression of early lesions in the rat.

De Miglio MR, Virdis P, Calvisi DF, Mele D, Muroni MR, Frau M, Pinna F, Tomasi ML, Simile MM, Pascale RM, Feo F.

Carcinogenesis. 2007 Nov;28(11):2367-74. Epub 2007 May 17.

PMID:
17510081
18.

Mapping a sex hormone-sensitive gene determining female resistance to liver carcinogenesis in a congenic F344.BN-Hcs4 rat.

De Miglio MR, Virdis P, Calvisi DF, Frau M, Muroni MR, Simile MM, Daino L, Careddu GM, Sanna-Passino E, Pascale RM, Feo F.

Cancer Res. 2006 Nov 1;66(21):10384-90.

19.

Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer.

Pascale RM, Simile MM, Calvisi DF, Frau M, Muroni MR, Seddaiu MA, Daino L, Muntoni MD, De Miglio MR, Thorgeirsson SS, Feo F.

Hepatology. 2005 Dec;42(6):1310-9.

PMID:
16317707
20.

Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition.

Feo F, De Miglio MR, Simile MM, Muroni MR, Calvisi DF, Frau M, Pascale RM.

Biochim Biophys Acta. 2006 Apr;1765(2):126-47. Epub 2005 Sep 15. Review.

PMID:
16216419
21.

Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis.

Simile MM, Pagnan G, Pastorino F, Brignole C, De Miglio MR, Muroni MR, Asara G, Frau M, Seddaiu MA, Calvisi DF, Feo F, Ponzoni M, Pascale RM.

Carcinogenesis. 2005 Feb;26(2):417-27. Epub 2004 Oct 21.

PMID:
15498786
22.

Polygenic control of hepatocarcinogenesis in Copenhagen x F344 rats.

De Miglio MR, Pascale RM, Simile MM, Muroni MR, Virdis P, Kwong KM, Wong LK, Bosinco GM, Pulina FR, Calvisi DF, Frau M, Wood GA, Archer MC, Feo F.

Int J Cancer. 2004 Aug 10;111(1):9-16.

23.

Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells.

Simile MM, De Miglio MR, Muroni MR, Frau M, Asara G, Serra S, Muntoni MD, Seddaiu MA, Daino L, Feo F, Pascale RM.

Carcinogenesis. 2004 Mar;25(3):333-41. Epub 2003 Nov 6.

PMID:
14604889
24.

Phenotypic reversion of rat neoplastic liver nodules is under genetic control.

De Miglio MR, Simile MM, Muroni MR, Calvisi DF, Virdis P, Asara G, Frau M, Bosinco GM, Seddaiu MA, Daino L, Feo F, Pascale RM.

Int J Cancer. 2003 May 20;105(1):70-5.

25.

Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats.

Falvella FS, Pascale RM, Gariboldi M, Manenti G, De Miglio MR, Simile MM, Dragani TA, Feo F.

Carcinogenesis. 2002 Nov;23(11):1933-6.

PMID:
12419843
26.

Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine.

Pascale RM, Simile MM, De Miglio MR, Feo F.

Alcohol. 2002 Jul;27(3):193-8. Review.

PMID:
12163149
27.

Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis.

De Miglio MR, Pascale RM, Simile MM, Muroni MR, Calvisi DF, Virdis P, Bosinco GM, Frau M, Seddaiu MA, Ladu S, Feo F.

Cancer Res. 2002 Aug 1;62(15):4459-63.

28.

Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis.

Pascale RM, Simile MM, De Miglio MR, Muroni MR, Calvisi DF, Asara G, Casabona D, Frau M, Seddaiu MA, Feo F.

Hepatology. 2002 Jun;35(6):1341-50.

PMID:
12029619
29.

Frequent loss of heterozygosity at the Hcr1 (hepatocarcinogenesis resistance) locus on chromosome 10 in primary hepatocellular carcinomas from LFF1 rat strain.

De Miglio MR, Muroni MR, Simile MM, Virdis P, Asara G, Frau M, Calvisi DF, Seddaiu MA, Pascale RM, Feo F.

Hepatology. 2001 May;33(5):1110-7.

PMID:
11343238
30.

5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.

Simile MM, Banni S, Angioni E, Carta G, De Miglio MR, Muroni MR, Calvisi DF, Carru A, Pascale RM, Feo F.

J Hepatol. 2001 Mar;34(3):386-94.

PMID:
11322199
31.

Genetic alterations in liver carcinogenesis: implications for new preventive and therapeutic strategies.

Feo F, Pascale RM, Simile MM, De Miglio MR, Muroni MR, Calvisi D.

Crit Rev Oncog. 2000;11(1):19-62. Review.

PMID:
10795626
32.

Implication of Bcl-2 family genes in basal and D-amphetamine-induced apoptosis in preneoplastic and neoplastic rat liver lesions.

De Miglio MR, Muroni MR, Simile MM, Calvisi DF, Tolu P, Deiana L, Carru A, Bonelli G, Feo F, Pascale RM.

Hepatology. 2000 Apr;31(4):956-65.

PMID:
10733553
33.

Identification of genetic loci controlling hepatocarcinogenesis on rat chromosomes 7 and 10.

De Miglio MR, Canzian F, Pascale RM, Simile MM, Muroni MR, Calvisi D, Romeo G, Feo F.

Cancer Res. 1999 Sep 15;59(18):4651-7.

34.

Analysis of loss of heterozygosity in neoplastic nodules induced by diethylnitrosamine in the resistant BFF1 rat strain.

Gariboldi M, Pascale R, Manenti G, De Miglio MR, Calvisi D, Carru A, Dragani TA, Feo F.

Carcinogenesis. 1999 Jul;20(7):1363-8.

PMID:
10383913
35.

Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain.

De Miglio MR, Simile MM, Muroni MR, Pusceddu S, Calvisi D, Carru A, Seddaiu MA, Daino L, Deiana L, Pascale RM, Feo F.

Mol Carcinog. 1999 May;25(1):21-9.

PMID:
10331741
36.

Transferrin and transferrin receptor gene expression and iron uptake in hepatocellular carcinoma in the rat.

Pascale RM, De Miglio MR, Muroni MR, Simile MM, Daino L, Seddaiu MA, Pusceddu S, Gaspa L, Calvisi D, Manenti G, Feo F.

Hepatology. 1998 Feb;27(2):452-61.

PMID:
9462644
37.

c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model.

Pascale RM, De Miglio MR, Muroni MR, Simile MM, Daino L, Seddaiu MA, Nufris A, Gaspa L, Deiana L, Feo F.

Int J Cancer. 1996 Sep 27;68(1):136-42.

38.

Persistent chemopreventive effect of S-adenosyl-L-methionine on the development of liver putative preneoplastic lesions induced by thiobenzamide in diethylnitrosamine-initiated rats.

Simile MM, Saviozzi M, De Miglio MR, Muroni MR, Nufris A, Pascale RM, Malvaldi G, Feo F.

Carcinogenesis. 1996 Jul;17(7):1533-7.

PMID:
8706260
39.

Inhibition by dehydroepiandrosterone of growth and progression of persistent liver nodules in experimental rat liver carcinogenesis.

Simile M, Pascale RM, De Miglio MR, Nufris A, Daino L, Seddaiu MA, Muroni MR, Rao KN, Feo F.

Int J Cancer. 1995 Jul 17;62(2):210-5.

PMID:
7622298
40.

Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase activity and gene expression by dehydroepiandrosterone in preneoplastic liver nodules.

Pascale RM, Simile MM, De Miglio MR, Nufris A, Seddaiu MA, Muroni MR, Danni O, Rao KN, Feo F.

Carcinogenesis. 1995 Jul;16(7):1537-42.

PMID:
7614686
41.

Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid.

Pascale RM, Simile MM, De Miglio MR, Nufris A, Daino L, Seddaiu MA, Rao PM, Rajalakshmi S, Sarma DS, Feo F.

Carcinogenesis. 1995 Feb;16(2):427-30.

PMID:
7859377
42.

Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis.

Simile MM, Pascale R, De Miglio MR, Nufris A, Daino L, Seddaiu MA, Gaspa L, Feo F.

Cancer Lett. 1994 Apr 29;79(1):9-16.

PMID:
7910516
43.

Effect of S-adenosyl-L-methionine on the development of preneoplastic foci and the activity of some carbohydrate metabolizing enzymes in the liver, during experimental hepatocarcinogenesis.

Gerbracht U, Eigenbrodt E, Simile MM, Pascale RM, Gaspa L, Daino L, Seddaiu MA, De Miglio MR, Nufris A, Feo F.

Anticancer Res. 1993 Nov-Dec;13(6A):1965-72.

PMID:
8297102

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