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Items: 1 to 50 of 116

1.

'Drc', a structurally novel ssDNA-binding transcription regulator of N4-related bacterial viruses.

Boon M, De Zitter E, De Smet J, Wagemans J, Voet M, Pennemann FL, Schalck T, Kuznedelov K, Severinov K, Van Meervelt L, De Maeyer M, Lavigne R.

Nucleic Acids Res. 2019 Nov 14. pii: gkz1048. doi: 10.1093/nar/gkz1048. [Epub ahead of print]

PMID:
31724707
2.

Olmesartan-induced enteropathy treated with budesonide.

Kempenaers S, Bogaert J, De Maeyer M, Van Hauthem P, Ramael M, Schoeters P.

Acta Gastroenterol Belg. 2019 Apr-Jun;82(2):319-321.

PMID:
31314195
3.

Structures of the heart specific SERCA2a Ca2+-ATPase.

Sitsel A, De Raeymaecker J, Drachmann ND, Derua R, Smaardijk S, Andersen JL, Vandecaetsbeek I, Chen J, De Maeyer M, Waelkens E, Olesen C, Vangheluwe P, Nissen P.

EMBO J. 2019 Mar 1;38(5). pii: e100020. doi: 10.15252/embj.2018100020. Epub 2019 Feb 18.

PMID:
30777856
4.

Caramel colour and process contaminants in foods and beverages: Part II - Occurrence data and exposure assessment of 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole (THI) and 4-methylimidazole (4-MEI) in Belgium.

Fierens T, Van Holderbeke M, Cornelis C, Jacobs G, Sioen I, De Maeyer M, Vinkx C, Vanermen G.

Food Chem. 2018 Jul 30;255:372-379. doi: 10.1016/j.foodchem.2018.02.013. Epub 2018 Feb 3.

PMID:
29571489
5.

Caramel colour and process by-products in foods and beverages: Part I - Development of a UPLC-MS/MS isotope dilution method for determination of 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole (THI), 4-methylimidazole (4-MEI) and 2-methylimidazol (2-MEI).

Jacobs G, Voorspoels S, Vloemans P, Fierens T, Van Holderbeke M, Cornelis C, Sioen I, De Maeyer M, Vinkx C, Vanermen G.

Food Chem. 2018 Jul 30;255:348-356. doi: 10.1016/j.foodchem.2018.02.039. Epub 2018 Feb 9.

PMID:
29571486
6.

Rational design of small molecules that modulate the transcriptional function of the response regulator PhoP.

Qing X, De Weerdt A, De Maeyer M, Steenackers H, Voet A.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):375-381. doi: 10.1016/j.bbrc.2017.11.037. Epub 2017 Nov 8.

PMID:
29127011
7.

Computational Studies of the Active and Inactive Regulatory Domains of Response Regulator PhoP Using Molecular Dynamics Simulations.

Qing XY, Steenackers H, Venken T, De Maeyer M, Voet A.

Mol Inform. 2017 Nov;36(11). doi: 10.1002/minf.201700031. Epub 2017 Jun 9.

PMID:
28598557
8.

Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).

Chen J, De Raeymaecker J, Hovgaard JB, Smaardijk S, Vandecaetsbeek I, Wuytack F, Møller JV, Eggermont J, De Maeyer M, Christensen SB, Vangheluwe P.

J Biol Chem. 2017 Apr 28;292(17):6938-6951. doi: 10.1074/jbc.M117.778431. Epub 2017 Mar 6.

9.

Effects of Histidine and β-alanine Supplementation on Human Muscle Carnosine Storage.

Blancquaert L, Everaert I, Missinne M, Baguet A, Stegen S, Volkaert A, Petrovic M, Vervaet C, Achten E, DE Maeyer M, DE Henauw S, Derave W.

Med Sci Sports Exerc. 2017 Mar;49(3):602-609. doi: 10.1249/MSS.0000000000001213.

PMID:
28106620
10.

Viral interference of the bacterial RNA metabolism machinery.

Dendooven T, Van den Bossche A, Hendrix H, Ceyssens PJ, Voet M, Bandyra KJ, De Maeyer M, Aertsen A, Noben JP, Hardwick SW, Luisi BF, Lavigne R.

RNA Biol. 2017 Jan 2;14(1):6-10. doi: 10.1080/15476286.2016.1251003. Epub 2016 Nov 11. Review.

11.

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.

Van den Bossche A, Hardwick SW, Ceyssens PJ, Hendrix H, Voet M, Dendooven T, Bandyra KJ, De Maeyer M, Aertsen A, Noben JP, Luisi BF, Lavigne R.

Elife. 2016 Jul 22;5. pii: e16413. doi: 10.7554/eLife.16413.

12.

Five lung nodules, four different pathologic findings: not all lung lesions are the same.

Toelen C, De Maeyer M, Van Schil P.

Acta Chir Belg. 2016 Dec;116(6):388-389. doi: 10.1080/00015458.2016.1171080. Epub 2016 Jul 4.

PMID:
27377101
13.

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.

Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C; BRIDGE-BPD Consortium, De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH.

Sci Transl Med. 2016 Mar 2;8(328):328ra30. doi: 10.1126/scitranslmed.aad7666. Epub 2016 Mar 2.

14.

The involvement of long-term serial-order memory in reading development: A longitudinal study.

Bogaerts L, Szmalec A, De Maeyer M, Page MP, Duyck W.

J Exp Child Psychol. 2016 May;145:139-56. doi: 10.1016/j.jecp.2015.12.008. Epub 2016 Feb 5.

PMID:
26835842
15.

Validation of APRI and FIB-4 score in an Antwerp cohort of chronic hepatitis C patients.

Verlinden W, Bourgeois S, De Maeyer M, Vonghia L, Vanwolleghem T, Michielsen P, Francque S.

Acta Gastroenterol Belg. 2015 Dec;78(4):373-80.

PMID:
26712046
16.

Mechanism of Nonpolar Model Substances to Inhibit Primary Gushing Induced by Hydrophobin HFBI.

Shokribousjein Z, Riveros Galan D, Losada-Pérez P, Wagner P, Lammertyn J, Arghir I, Golreihan A, Verachtert H, Aydın AA, De Maeyer M, Titze J, Ilberg V, Derdelinckx G.

J Agric Food Chem. 2015 May 13;63(18):4673-82. doi: 10.1021/acs.jafc.5b01170. Epub 2015 Apr 30.

PMID:
25891388
17.

Reporting accuracy of population dietary sodium intake using duplicate 24 h dietary recalls and a salt questionnaire.

De Keyzer W, Dofková M, Lillegaard IT, De Maeyer M, Andersen LF, Ruprich J, Řehůřková I, Geelen A, van 't Veer P, De Henauw S, Crispim SP, de Boer E, Ocké M, Slimani N, Huybrechts I.

Br J Nutr. 2015 Feb 14;113(3):488-97. doi: 10.1017/S0007114514003791. Epub 2015 Jan 13.

PMID:
25582315
18.

HIV-1 integrase variants retarget viral integration and are associated with disease progression in a chronic infection cohort.

Demeulemeester J, Vets S, Schrijvers R, Madlala P, De Maeyer M, De Rijck J, Ndung'u T, Debyser Z, Gijsbers R.

Cell Host Microbe. 2014 Nov 12;16(5):651-62. doi: 10.1016/j.chom.2014.09.016. Epub 2014 Nov 12.

19.

The novel ADAMTS13-p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice.

De Cock E, Hermans C, De Raeymaecker J, De Ceunynck K, De Maeyer B, Vandeputte N, Vandenbulcke A, Deckmyn H, Rottensteiner H, De Maeyer M, De Meyer SF, Vanhoorelbeke K.

J Thromb Haemost. 2015 Feb;13(2):283-92. doi: 10.1111/jth.12804. Epub 2015 Jan 17.

20.

A semi-probabilistic modelling approach for the estimation of dietary exposure to phthalates in the Belgian adult population.

Fierens T, Standaert A, Cornelis C, Sioen I, De Henauw S, Willems H, Bellemans M, De Maeyer M, Van Holderbeke M.

Environ Int. 2014 Dec;73:117-27. doi: 10.1016/j.envint.2014.07.017. Epub 2014 Aug 9.

21.

In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2.

Vancraenenbroeck R, De Raeymaecker J, Lobbestael E, Gao F, De Maeyer M, Voet A, Baekelandt V, Taymans JM.

Front Mol Neurosci. 2014 Jun 3;7:51. doi: 10.3389/fnmol.2014.00051. eCollection 2014.

22.

Comparison of two food record-based dietary assessment methods for a pan-European food consumption survey among infants, toddlers, and children using data quality indicators.

Freisling H, Ocké MC, Casagrande C, Nicolas G, Crispim SP, Niekerk M, van der Laan J, de Boer E, Vandevijvere S, de Maeyer M, Ruprich J, Dofkova M, Huybrechts I, Trolle E, Slimani N.

Eur J Nutr. 2015 Apr;54(3):437-45. doi: 10.1007/s00394-014-0727-7. Epub 2014 Jun 11.

PMID:
24916012
23.

Autolytic degradation of ocriplasmin: a complex mechanism unraveled by mutational analysis.

Noppen B, Fonteyn L, Aerts F, De Vriese A, De Maeyer M, Le Floch F, Barbeaux P, Zwaal R, Vanhove M.

Protein Eng Des Sel. 2014 Jul;27(7):215-23. doi: 10.1093/protein/gzu015. Epub 2014 May 1.

PMID:
24795342
24.

LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014).

Demeulemeester J, Chaltin P, Marchand A, De Maeyer M, Debyser Z, Christ F.

Expert Opin Ther Pat. 2014 Jun;24(6):609-32. doi: 10.1517/13543776.2014.898753. Epub 2014 Mar 25. Review.

PMID:
24666332
25.

Assessment of mycotoxin exposure in the Belgian population using biomarkers: aim, design and methods of the BIOMYCO study.

Heyndrickx E, Sioen I, Bellemans M, De Maeyer M, Callebaut A, De Henauw S, De Saeger S.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2014;31(5):924-31. doi: 10.1080/19440049.2014.900192. Epub 2014 Apr 10.

PMID:
24597722
26.

Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor.

Cavalluzzo C, Christ F, Voet A, Sharma A, Singh BK, Zhang KY, Lescrinier E, De Maeyer M, Debyser Z, Van der Eycken E.

J Pept Sci. 2013 Oct;19(10):651-8. doi: 10.1002/psc.2543. Epub 2013 Aug 27.

PMID:
24014475
27.

Tuning the size and properties of ClyA nanopores assisted by directed evolution.

Soskine M, Biesemans A, De Maeyer M, Maglia G.

J Am Chem Soc. 2013 Sep 11;135(36):13456-63. doi: 10.1021/ja4053398. Epub 2013 Aug 27.

28.

Rapid Conformational Fluctuations of Disordered HIV-1 Fusion Peptide in Solution.

Venken T, Voet A, De Maeyer M, De Fabritiis G, Sadiq SK.

J Chem Theory Comput. 2013 Jul 9;9(7):2870-4. doi: 10.1021/ct300856r. Epub 2013 Jun 3.

PMID:
26583970
29.

Dietary intake and food sources of total and individual polyunsaturated fatty acids in the Belgian population over 15 years old.

Sioen I, Vyncke K, De Maeyer M, Gerichhausen M, De Henauw S.

Lipids. 2013 Jul;48(7):729-38. doi: 10.1007/s11745-013-3788-0. Epub 2013 Apr 16.

PMID:
23588778
30.

Mapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein Rev.

Vercruysse T, Boons E, Venken T, Vanstreels E, Voet A, Steyaert J, De Maeyer M, Daelemans D.

PLoS One. 2013;8(4):e60259. doi: 10.1371/journal.pone.0060259. Epub 2013 Apr 2.

31.

Understanding the role of defective invertases in plants: tobacco Nin88 fails to degrade sucrose.

Le Roy K, Vergauwen R, Struyf T, Yuan S, Lammens W, Mátrai J, De Maeyer M, Van den Ende W.

Plant Physiol. 2013 Apr;161(4):1670-81. doi: 10.1104/pp.112.209460. Epub 2013 Feb 27.

32.

An integrated fragment based screening approach for the discovery of small molecule modulators of the VWF-GPIbα interaction.

Jose RA, Voet A, Broos K, Jakobi AJ, Bruylants G, Egle B, Zhang KY, De Maeyer M, Deckmyn H, De Borggraeve WM.

Chem Commun (Camb). 2012 Nov 28;48(92):11349-51. doi: 10.1039/c2cc35269a.

PMID:
23072895
33.

Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers.

Civiero L, Vancraenenbroeck R, Belluzzi E, Beilina A, Lobbestael E, Reyniers L, Gao F, Micetic I, De Maeyer M, Bubacco L, Baekelandt V, Cookson MR, Greggio E, Taymans JM.

PLoS One. 2012;7(8):e43472. doi: 10.1371/journal.pone.0043472. Epub 2012 Aug 29.

34.

Phthalates dietary exposure and food sources for Belgian preschool children and adults.

Sioen I, Fierens T, Van Holderbeke M, Geerts L, Bellemans M, De Maeyer M, Servaes K, Vanermen G, Boon PE, De Henauw S.

Environ Int. 2012 Nov 1;48:102-8. doi: 10.1016/j.envint.2012.07.004. Epub 2012 Aug 9.

PMID:
22885666
35.

pKa modulation of the acid/base catalyst within GH32 and GH68: a role in substrate/inhibitor specificity?

Yuan S, Le Roy K, Venken T, Lammens W, Van den Ende W, De Maeyer M.

PLoS One. 2012;7(5):e37453. doi: 10.1371/journal.pone.0037453. Epub 2012 May 25.

36.

Evidence for DNA-binding domain--ligand-binding domain communications in the androgen receptor.

Helsen C, Dubois V, Verfaillie A, Young J, Trekels M, Vancraenenbroeck R, De Maeyer M, Claessens F.

Mol Cell Biol. 2012 Aug;32(15):3033-43. doi: 10.1128/MCB.00151-12. Epub 2012 May 29.

37.

Computational investigation of the HIV-1 Rev multimerization using molecular dynamics simulations and binding free energy calculations.

Venken T, Daelemans D, De Maeyer M, Voet A.

Proteins. 2012 Jun;80(6):1633-46. doi: 10.1002/prot.24057. Epub 2012 Mar 23.

PMID:
22447650
38.

Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2.

Vancraenenbroeck R, Lobbestael E, Weeks SD, Strelkov SV, Baekelandt V, Taymans JM, De Maeyer M.

Biochim Biophys Acta. 2012 Mar;1824(3):450-60. doi: 10.1016/j.bbapap.2011.12.009. Epub 2012 Jan 11.

PMID:
22251894
39.

Identification of a small molecule that modulates platelet glycoprotein Ib-von Willebrand factor interaction.

Broos K, Trekels M, Jose RA, Demeulemeester J, Vandenbulcke A, Vandeputte N, Venken T, Egle B, De Borggraeve WM, Deckmyn H, De Maeyer M.

J Biol Chem. 2012 Mar 16;287(12):9461-72. doi: 10.1074/jbc.M111.311431. Epub 2012 Jan 9.

40.

Food sources and correlates of sodium and potassium intakes in Flemish pre-school children.

Huybrechts I, De Keyzer W, Lin Y, Vandevijvere S, Vereecken C, Van Oyen H, Tilleman K, Bellemans M, De Maeyer M, De Backer G, De Henauw S.

Public Health Nutr. 2012 Jun;15(6):1039-46. doi: 10.1017/S1368980011002497. Epub 2011 Oct 6.

PMID:
22014724
41.

An optimized MM/PBSA virtual screening approach applied to an HIV-1 gp41 fusion peptide inhibitor.

Venken T, Krnavek D, Münch J, Kirchhoff F, Henklein P, De Maeyer M, Voet A.

Proteins. 2011 Nov;79(11):3221-35. doi: 10.1002/prot.23158. Epub 2011 Aug 30.

PMID:
21989940
42.

LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding.

Taymans JM, Vancraenenbroeck R, Ollikainen P, Beilina A, Lobbestael E, De Maeyer M, Baekelandt V, Cookson MR.

PLoS One. 2011;6(8):e23207. doi: 10.1371/journal.pone.0023207. Epub 2011 Aug 12.

43.

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

Monaco G, Decrock E, Akl H, Ponsaerts R, Vervliet T, Luyten T, De Maeyer M, Missiaen L, Distelhorst CW, De Smedt H, Parys JB, Leybaert L, Bultynck G.

Cell Death Differ. 2012 Feb;19(2):295-309. doi: 10.1038/cdd.2011.97. Epub 2011 Aug 5.

44.

The standardized computerized 24-h dietary recall method EPIC-Soft adapted for pan-European dietary monitoring.

Slimani N, Casagrande C, Nicolas G, Freisling H, Huybrechts I, Ocké MC, Niekerk EM, van Rossum C, Bellemans M, De Maeyer M, Lafay L, Krems C, Amiano P, Trolle E, Geelen A, de Vries JH, de Boer EJ; EFCOVAL Consortium.

Eur J Clin Nutr. 2011 Jul;65 Suppl 1:S5-15. doi: 10.1038/ejcn.2011.83.

PMID:
21731006
45.

Inventory of experiences from national/regional dietary monitoring surveys using EPIC-Soft.

Huybrechts I, Casagrande C, Nicolas G, Geelen A, Crispim SP, De Keyzer W, Freisling H, De Henauw S, De Maeyer M, Krems C, Amiano P, de Boer EJ, Ocké MC, de Vries JH, Slimani N; EFCOVAL Consortium.

Eur J Clin Nutr. 2011 Jul;65 Suppl 1:S16-28. doi: 10.1038/ejcn.2011.84.

PMID:
21731002
46.

Structure based discovery of small molecule suppressors targeting bacterial lysozyme inhibitors.

Voet A, Callewaert L, Ulens T, Vanderkelen L, Vanherreweghe JM, Michiels CW, De Maeyer M.

Biochem Biophys Res Commun. 2011 Feb 25;405(4):527-32. doi: 10.1016/j.bbrc.2011.01.053. Epub 2011 Jan 20.

PMID:
21256115
47.

Food photographs in nutritional surveillance: errors in portion size estimation using drawings of bread and photographs of margarine and beverages consumption.

De Keyzer W, Huybrechts I, De Maeyer M, Ocké M, Slimani N, van 't Veer P, De Henauw S.

Br J Nutr. 2011 Apr;105(7):1073-83. doi: 10.1017/S0007114510004551. Epub 2010 Nov 24.

PMID:
21092383
48.

Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant.

Daniëls V, Vancraenenbroeck R, Law BM, Greggio E, Lobbestael E, Gao F, De Maeyer M, Cookson MR, Harvey K, Baekelandt V, Taymans JM.

J Neurochem. 2011 Jan;116(2):304-15. doi: 10.1111/j.1471-4159.2010.07105.x.

49.

Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication.

Christ F, Voet A, Marchand A, Nicolet S, Desimmie BA, Marchand D, Bardiot D, Van der Veken NJ, Van Remoortel B, Strelkov SV, De Maeyer M, Chaltin P, Debyser Z.

Nat Chem Biol. 2010 Jun;6(6):442-8. doi: 10.1038/nchembio.370. Epub 2010 May 16.

PMID:
20473303
50.

Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump.

Vandecaetsbeek I, Trekels M, De Maeyer M, Ceulemans H, Lescrinier E, Raeymaekers L, Wuytack F, Vangheluwe P.

Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18533-8. doi: 10.1073/pnas.0906797106. Epub 2009 Oct 21.

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