Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 26

1.

Discovery of Enhancers of the Secretion of Leukemia Inhibitory Factor for the Treatment of Multiple Sclerosis.

Vela L, Caballero I, Fang L, Liu Q, Ramón F, Díez E, de Los Frailes M.

J Biomol Screen. 2016 Jun;21(5):437-45. doi: 10.1177/1087057116638821. Epub 2016 Mar 16.

PMID:
26984928
2.

Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF).

Zapatero MC, Pérez P, Vázquez MJ, Colmenarejo G, de Los Frailes M, Ramón F.

J Biomol Screen. 2016 Jun;21(5):446-58. doi: 10.1177/1087057116633997. Epub 2016 Mar 1.

PMID:
26933127
3.

Mining Natural-Products Screening Data for Target-Class Chemical Motifs.

Coma I, Bandyopadhyay D, Diez E, Ruiz EA, de los Frailes MT, Colmenarejo G.

J Biomol Screen. 2014 Jun;19(5):749-57. doi: 10.1177/1087057114521463. Epub 2014 Feb 11.

PMID:
24518065
4.

The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2.

D'Alessandro PL, Corti C, Roth A, Ugolini A, Sava A, Montanari D, Bianchi F, Garland SL, Powney B, Koppe EL, Rocheville M, Osborne G, Perez P, de la Fuente J, De Los Frailes M, Smith PW, Branch C, Nash D, Watson SP.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):759-62. doi: 10.1016/j.bmcl.2009.11.032. Epub 2009 Nov 26.

PMID:
20005096
5.

Discovery of 3-aryl-4-isoxazolecarboxamides as TGR5 receptor agonists.

Evans KA, Budzik BW, Ross SA, Wisnoski DD, Jin J, Rivero RA, Vimal M, Szewczyk GR, Jayawickreme C, Moncol DL, Rimele TJ, Armour SL, Weaver SP, Griffin RJ, Tadepalli SM, Jeune MR, Shearer TW, Chen ZB, Chen L, Anderson DL, Becherer JD, De Los Frailes M, Colilla FJ.

J Med Chem. 2009 Dec 24;52(24):7962-5. doi: 10.1021/jm901434t.

PMID:
19902954
6.

Screening technologies for G protein-coupled receptors: from HTS to uHTS.

De los Frailes M, Diez E.

Methods Mol Biol. 2009;552:15-37. doi: 10.1007/978-1-60327-317-6_2.

PMID:
19513639
7.

Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification.

Heightman TD, Scott JS, Longley M, Bordas V, Dean DK, Elliott R, Hutley G, Witherington J, Abberley L, Passingham B, Berlanga M, de Los Frailes M, Wise A, Powney B, Muir A, McKay F, Butler S, Winborn K, Gardner C, Darton J, Campbell C, Sanger G.

Bioorg Med Chem Lett. 2007 Dec 1;17(23):6584-7. Epub 2007 Sep 25.

PMID:
17942309
8.

Identification of novel isoform-selective inhibitors within class I histone deacetylases.

Hu E, Dul E, Sung CM, Chen Z, Kirkpatrick R, Zhang GF, Johanson K, Liu R, Lago A, Hofmann G, Macarron R, de los Frailes M, Perez P, Krawiec J, Winkler J, Jaye M.

J Pharmacol Exp Ther. 2003 Nov;307(2):720-8. Epub 2003 Sep 15.

PMID:
12975486
9.

Effect of potassium-induced depolarization on somatostatin gene expression in cultured fetal rat cerebrocortical cells.

Tolón RM, Sánchez Franco F, de los Frailes MT, Lorenzo MJ, Cacicedo L.

J Neurosci. 1994 Mar;14(3 Pt 1):1053-9.

10.

Biosynthesis of growth hormone-releasing factor by fetal rat cerebrocortical and hypothalamic cells.

Fernández Vázquez G, Cacicedo L, Lorenzo MJ, de los Frailes MT, Lara JI, Sánchez Franco F.

Peptides. 1994;15(5):825-8.

PMID:
7984501
11.

Growth hormone-releasing factor regulation by somatostatin, growth hormone and insulin-like growth factor I in fetal rat hypothalamic-brain stem cell cocultures.

Fernández Vázquez G, Cacicedo L, de los Frailes MT, Lorenzo MJ, Tolón R, Sánchez Franco F.

Neuroendocrinology. 1993 Dec;58(6):655-65.

PMID:
7907399
12.

Neurotransmitter regulation of somatostatin secretion by fetal rat cerebral cortical cells in culture.

de los Frailes MT, Cacicedo L, Lorenzo MJ, Tolón RM, Fernández G, Sánchez Franco F.

J Endocrinol Invest. 1993 Oct;16(9):661-8.

PMID:
7904279
13.

Pituitary and peripheral insulin-like growth factor-I regulation by thyroid hormone.

Cacicedo L, de los Frailes MT, Lorenzo MJ, Sanchez Franco F.

Ann N Y Acad Sci. 1993 Aug 27;692:287-90. No abstract available.

PMID:
8215034
14.

Purification and characterization of the CA 125 tumor-associated antigen from human ascites.

de los Frailes MT, Stark S, Jaeger W, Hoerauf A, Wildt L.

Tumour Biol. 1993;14(1):18-29.

PMID:
7684153
15.

Regulation of somatostatin and growth hormone-releasing factor by gonadal steroids in fetal rat hypothalamic cells in culture.

Fernández G, Sánchez-Franco F, de los Frailes MT, Tolón RM, Lorenzo MJ, López J, Cacicedo L.

Regul Pept. 1992 Dec 11;42(3):135-44.

PMID:
1363251
16.

Role of locally produced growth hormone-releasing factor in somatostatin regulation by fetal rat brain cells in culture.

de los Frailes MT, Cacicedo L, Fernandez G, Tolón RM, Jesus Lorenzo M, Aguado F, Sánchez Franco F.

Neuroendocrinology. 1992 Feb;55(2):221-9.

PMID:
1352390
17.

Thyroid hormones regulate release and content of vasoactive intestinal peptide in cultured fetal cerebral cortical cells.

Lorenzo MJ, Sánchez-Franco F, de los Frailes MT, Tolón RM, Fernández G, Cacicedo L.

Neuroendocrinology. 1992 Jan;55(1):59-65.

PMID:
1608509
18.

Endogenous vasoactive intestinal peptide (VIP) regulates somatostatin secretion by cultured fetal rat cerebral cortical and hypothalamic cells.

De los Frailes MT, Sanchez Franco F, Lorenzo MJ, Tolón RM, Lara JI, Cacicedo L.

Regul Pept. 1991 Jul 9;34(3):261-74.

PMID:
1681571
19.

Neurosecretory and trophic action on fetal rat neuroblasts induced by an amino acid mixture.

Sanchez-Franco F, Cacicedo L, Lorenzo MJ, de los Frailes MT, Fernandez G, Delgado JM.

Biochem Med Metab Biol. 1990 Feb;43(1):10-21.

PMID:
1968752
20.

Influence of thyroid hormones on somatostatin processing in cultured cerebro-cortical cells.

de los Frailes MT, Sanchez Franco F, Lorenzo MJ, Tolón R, Cacicedo L.

Neuropeptides. 1990 Jan;15(1):25-30.

PMID:
1970133
21.

Depolarizing influences regulate somatostatin synthesis and processing in cultured cerebral cortical cells.

de los Frailes MT, Sánchez-Franco F, Lorenzo MJ, Fernandez Vazquez G, Cacicedo L.

Regul Pept. 1990 Jan;27(1):97-105.

PMID:
1968675
22.

Secretions of somatostatin and VIP in cultures of fetal rat neuroblasts increased by amino acids.

Delgado JM, Cacicedo L, Lorenzo MJ, de los Frailes MT, Sanchez-Franco F.

Life Sci. 1990;46(1):55-8.

PMID:
1967811
23.

Growth hormone-releasing factor production by fetal rat cerebrocortical and hypothalamic cells in primary culture.

Fernandez G, Cacicedo L, Lorenzo MJ, de los Frailes MT, Sanchez Franco F.

Endocrinology. 1989 Oct;125(4):1991-8.

PMID:
2507287
24.

Synthesis and secretion of vasoactive intestinal peptide by rat fetal cerebral cortical and hypothalamic cells in culture.

Lorenzo MJ, Sánchez-Franco F, de los Frailes MT, Reichlin S, Férnandez G, Cacicedo L.

Endocrinology. 1989 Oct;125(4):1983-90.

PMID:
2507286
25.

Divergent effects of acute depolarization on somatostatin release and protein synthesis in cultured fetal and neonatal rat brain cells.

de los Frailes MT, Cacicedo L, Lorenzo MJ, Sánchez-Franco F.

J Neurochem. 1989 May;52(5):1333-9.

PMID:
2468735
26.

Thyroid hormone action on biosynthesis of somatostatin by fetal rat brain cells in culture.

de los Frailes MT, Cacicedo L, Lorenzo MJ, Fernandez G, Sanchez-Franco F.

Endocrinology. 1988 Aug;123(2):898-904.

PMID:
2899503

Supplemental Content

Loading ...
Support Center