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Items: 1 to 50 of 58

1.

p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling.

Chiche A, Di-Cicco A, Sesma-Sanz L, Bresson L, de la Grange P, Glukhova MA, Faraldo MM, Deugnier MA.

Breast Cancer Res. 2019 Jan 25;21(1):13. doi: 10.1186/s13058-019-1101-8.

2.

Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia.

Domenech C, Maillard L, Rousseau A, Guidez F, Petit L, Pla M, Clay D, Guimiot F, Sanfilippo S, Jacques S, de la Grange P, Robil N, Soulier J, Souyri M.

Stem Cell Reports. 2018 Nov 13;11(5):1075-1091. doi: 10.1016/j.stemcr.2018.10.001. Epub 2018 Oct 25.

3.

The iron chelator deferasirox synergises with chemotherapy to treat triple-negative breast cancers.

Tury S, Assayag F, Bonin F, Chateau-Joubert S, Servely JL, Vacher S, Becette V, Caly M, Rapinat A, Gentien D, de la Grange P, Schnitzler A, Lallemand F, Marangoni E, Bièche I, Callens C.

J Pathol. 2018 Sep;246(1):103-114. doi: 10.1002/path.5104. Epub 2018 Aug 7.

PMID:
29876931
4.

Identification of novel recurrent ETV6-IgH fusions in primary central nervous system lymphoma.

Bruno A, Labreche K, Daniau M, Boisselier B, Gauchotte G, Royer-Perron L, Rahimian A, Lemoine F, de la Grange P, Guégan J, Bielle F, Polivka M, Adam C, Meyronet D, Figarella-Branger D, Villa C, Chrétien F, Eimer S, Davi F, Rousseau A, Houillier C, Soussain C, Mokhtari K, Hoang-Xuan K, Alentorn A.

Neuro Oncol. 2018 Jul 5;20(8):1092-1100. doi: 10.1093/neuonc/noy019.

PMID:
29432597
5.

[Neurotrophic factors for motor neurons: an à la carte menu].

Alory A, Jacquier A, Gentien D, de la Grange P, Haase G.

Med Sci (Paris). 2017 Oct;33(10):835-839. doi: 10.1051/medsci/20173310008. Epub 2017 Oct 10. French. No abstract available.

6.

Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer.

Davy G, Rousselin A, Goardon N, Castéra L, Harter V, Legros A, Muller E, Fouillet R, Brault B, Smirnova AS, Lemoine F, de la Grange P, Guillaud-Bataille M, Caux-Moncoutier V, Houdayer C, Bonnet F, Blanc-Fournier C, Gaildrat P, Frebourg T, Martins A, Vaur D, Krieger S.

Eur J Hum Genet. 2017 Oct;25(10):1147-1154. doi: 10.1038/ejhg.2017.116. Epub 2017 Jul 26.

7.

Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness.

Sharma S, Maras JS, Das S, Hussain S, Mishra AK, Shasthry SM, Sharma CB, Weiss E, Elkrief L, Rautou PE, Gilgenkrantz H, Lotersztajn S, Paradis V, de la Grange P, Junot C, Moreau R, Sarin SK.

Sci Rep. 2017 Jul 28;7(1):6816. doi: 10.1038/s41598-017-07161-4.

8.

Alternative splicing of CNOT7 diversifies CCR4-NOT functions.

Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L.

Nucleic Acids Res. 2017 Aug 21;45(14):8508-8523. doi: 10.1093/nar/gkx506.

9.

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.

Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, De la Grange P, Sette C.

Dev Cell. 2017 Apr 10;41(1):82-93.e4. doi: 10.1016/j.devcel.2017.03.003. Epub 2017 Mar 30.

10.

Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.

Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2486-E2493. doi: 10.1073/pnas.1615372114. Epub 2017 Mar 7.

11.

[Deregulation of pre-messenger RNA splicing and rare diseases].

de la Grange P.

Med Sci (Paris). 2016 Dec;32(12):1111-1119. doi: 10.1051/medsci/20163212015. Epub 2017 Jan 3. Review. French.

12.

Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.

Weiss E, Rautou PE, Fasseu M, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec M, Pilard N, Lebrec D, Valla D, Durand F, de la Grange P, Monteiro RC, Paugam-Burtz C, Lotersztajn S, Moreau R.

J Hepatol. 2017 May;66(5):930-941. doi: 10.1016/j.jhep.2016.12.008. Epub 2016 Dec 28.

PMID:
28040548
13.

Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy.

Møller RS, Weckhuysen S, Chipaux M, Marsan E, Taly V, Bebin EM, Hiatt SM, Prokop JW, Bowling KM, Mei D, Conti V, de la Grange P, Ferrand-Sorbets S, Dorfmüller G, Lambrecq V, Larsen LH, Leguern E, Guerrini R, Rubboli G, Cooper GM, Baulac S.

Neurol Genet. 2016 Oct 31;2(6):e118. eCollection 2016 Dec.

14.

Clinical-scale validation of a new efficient procedure for cryopreservation of ex vivo expanded cord blood hematopoietic stem and progenitor cells.

Duchez P, Rodriguez L, Chevaleyre J, De La Grange PB, Ivanovic Z.

Cytotherapy. 2016 Dec;18(12):1543-1547. doi: 10.1016/j.jcyt.2016.08.004. Epub 2016 Aug 31.

PMID:
27592406
15.

p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors.

Chiche A, Moumen M, Romagnoli M, Petit V, Lasla H, Jézéquel P, de la Grange P, Jonkers J, Deugnier MA, Glukhova MA, Faraldo MM.

Oncogene. 2017 Apr 27;36(17):2355-2365. doi: 10.1038/onc.2016.396. Epub 2016 Oct 24.

PMID:
27775073
16.

Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.

Klein P, Oloko M, Roth F, Montel V, Malerba A, Jarmin S, Gidaro T, Popplewell L, Perie S, Lacau St Guily J, de la Grange P, Antoniou MN, Dickson G, Butler-Browne G, Bastide B, Mouly V, Trollet C.

Nucleic Acids Res. 2016 Dec 15;44(22):10929-10945. Epub 2016 Aug 9.

17.

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization.

Vallerand D, Massonnet G, Kébir F, Gentien D, Maciorowski Z, De la Grange P, Sigal-Zafrani B, Richardson M, Humbert S, Thuleau A, Assayag F, de Plater L, Nicolas A, Scholl S, Marangoni E, Weigand S, Roman-Roman S, Savina A, Decaudin D.

PLoS One. 2016 Jul 7;11(7):e0157670. doi: 10.1371/journal.pone.0157670. eCollection 2016.

18.

Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons.

Bellouze S, Baillat G, Buttigieg D, de la Grange P, Rabouille C, Haase G.

Mol Neurodegener. 2016 Jun 9;11(1):43. doi: 10.1186/s13024-016-0111-6.

19.

Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia.

Weckhuysen S, Marsan E, Lambrecq V, Marchal C, Morin-Brureau M, An-Gourfinkel I, Baulac M, Fohlen M, Kallay Zetchi C, Seeck M, de la Grange P, Dermaut B, Meurs A, Thomas P, Chassoux F, Leguern E, Picard F, Baulac S.

Epilepsia. 2016 Jun;57(6):994-1003. doi: 10.1111/epi.13391. Epub 2016 May 13.

20.

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways.

Guerenne L, Beurlet S, Said M, Gorombei P, Le Pogam C, Guidez F, de la Grange P, Omidvar N, Vanneaux V, Mills K, Mufti GJ, Sarda-Mantel L, Noguera ME, Pla M, Fenaux P, Padua RA, Chomienne C, Krief P.

J Hematol Oncol. 2016 Jan 27;9:5. doi: 10.1186/s13045-016-0235-8.

21.

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models.

Colombrita C, Onesto E, Buratti E, de la Grange P, Gumina V, Baralle FE, Silani V, Ratti A.

Biochim Biophys Acta. 2015 Dec;1849(12):1398-410. doi: 10.1016/j.bbagrm.2015.10.015. Epub 2015 Oct 26.

PMID:
26514432
22.

Molecular analyses of juvenile granulosa cell tumors bearing AKT1 mutations provide insights into tumor biology and therapeutic leads.

Auguste A, Bessière L, Todeschini AL, Caburet S, Sarnacki S, Prat J, D'angelo E, De La Grange P, Ariste O, Lemoine F, Legois B, Sultan C, Zider A, Galmiche L, Kalfa N, Veitia RA.

Hum Mol Genet. 2015 Dec 1;24(23):6687-98. doi: 10.1093/hmg/ddv373. Epub 2015 Sep 11.

PMID:
26362254
23.

SNORD116 and SNORD115 change expression of multiple genes and modify each other's activity.

Falaleeva M, Surface J, Shen M, de la Grange P, Stamm S.

Gene. 2015 Nov 10;572(2):266-73. doi: 10.1016/j.gene.2015.07.023. Epub 2015 Jul 26.

24.

DUSP4-mediated accelerated T-cell senescence in idiopathic CD4 lymphopenia.

Bignon A, Régent A, Klipfel L, Desnoyer A, de la Grange P, Martinez V, Lortholary O, Dalloul A, Mouthon L, Balabanian K.

Blood. 2015 Apr 16;125(16):2507-18. doi: 10.1182/blood-2014-08-598565. Epub 2015 Mar 2.

25.

Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma.

Vogt N, Gibaud A, Lemoine F, de la Grange P, Debatisse M, Malfoy B.

Nucleic Acids Res. 2014 Dec 1;42(21):13194-205. doi: 10.1093/nar/gku1101. Epub 2014 Nov 6.

26.

Acquired resistance to endocrine treatments is associated with tumor-specific molecular changes in patient-derived luminal breast cancer xenografts.

Cottu P, Bièche I, Assayag F, El Botty R, Chateau-Joubert S, Thuleau A, Bagarre T, Albaud B, Rapinat A, Gentien D, de la Grange P, Sibut V, Vacher S, Hatem R, Servely JL, Fontaine JJ, Decaudin D, Pierga JY, Roman-Roman S, Marangoni E.

Clin Cancer Res. 2014 Aug 15;20(16):4314-25. doi: 10.1158/1078-0432.CCR-13-3230. Epub 2014 Jun 19.

27.

Sudemycin E influences alternative splicing and changes chromatin modifications.

Convertini P, Shen M, Potter PM, Palacios G, Lagisetti C, de la Grange P, Horbinski C, Fondufe-Mittendorf YN, Webb TR, Stamm S.

Nucleic Acids Res. 2014 Apr;42(8):4947-61. doi: 10.1093/nar/gku151. Epub 2014 Mar 11.

28.

A gene expression and pre-mRNA splicing signature that marks the adenoma-adenocarcinoma progression in colorectal cancer.

Pesson M, Volant A, Uguen A, Trillet K, De La Grange P, Aubry M, Daoulas M, Robaszkiewicz M, Le Gac G, Morel A, Simon B, Corcos L.

PLoS One. 2014 Feb 6;9(2):e87761. doi: 10.1371/journal.pone.0087761. eCollection 2014.

29.
30.

Valproic acid causes proteasomal degradation of DICER and influences miRNA expression.

Zhang Z, Convertini P, Shen M, Xu X, Lemoine F, de la Grange P, Andres DA, Stamm S.

PLoS One. 2013 Dec 17;8(12):e82895. doi: 10.1371/journal.pone.0082895. eCollection 2013.

31.

CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.

Astori A, Fredly H, Aloysius TA, Bullinger L, Mansat-De Mas V, de la Grange P, Delhommeau F, Hagen KM, Récher C, Dusanter-Fourt I, Knappskog S, Lillehaug JR, Pendino F, Bruserud Ø.

Oncotarget. 2013 Sep;4(9):1438-48.

32.

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells.

Beurlet S, Omidvar N, Gorombei P, Krief P, Le Pogam C, Setterblad N, de la Grange P, Leboeuf C, Janin A, Noguera ME, Hervatin F, Sarda-Mantel L, Konopleva M, Andreeff M, Tu AW, Fan AC, Felsher DW, Whetton A, Pla M, West R, Fenaux P, Chomienne C, Padua RA.

Blood. 2013 Oct 17;122(16):2864-76. doi: 10.1182/blood-2012-07-445635. Epub 2013 Aug 13.

33.

SF3B1 mutations are associated with alternative splicing in uveal melanoma.

Furney SJ, Pedersen M, Gentien D, Dumont AG, Rapinat A, Desjardins L, Turajlic S, Piperno-Neumann S, de la Grange P, Roman-Roman S, Stern MH, Marais R.

Cancer Discov. 2013 Oct;3(10):1122-1129. doi: 10.1158/2159-8290.CD-13-0330. Epub 2013 Jul 16.

34.

Molecular characterization of a patient presumed to have prader-willi syndrome.

Falaleeva M, Sulsona CR, Zielke HR, Currey KM, de la Grange P, Aslanzadeh V, Driscoll DJ, Stamm S.

Clin Med Insights Case Rep. 2013 May 5;6:79-86. doi: 10.4137/CCRep.S11510. Print 2013.

35.

Human induced pluripotent stem cells as a tool to model a form of Leber congenital amaurosis.

Lustremant C, Habeler W, Plancheron A, Goureau O, Grenot L, de la Grange P, Audo I, Nandrot EF, Monville C.

Cell Reprogram. 2013 Jun;15(3):233-46. doi: 10.1089/cell.2012.0076. Epub 2013 May 10.

PMID:
23663011
36.

Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.

Convertini P, Zhang J, de la Grange P, Hayward LJ, Zhu H, Stamm S.

Biochim Biophys Acta. 2013 Aug;1832(8):1129-35. doi: 10.1016/j.bbadis.2013.03.015. Epub 2013 Mar 29.

37.

Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure.

Shen M, Bellaousov S, Hiller M, de La Grange P, Creamer TP, Malina O, Sperling R, Mathews DH, Stoilov P, Stamm S.

Nucleic Acids Res. 2013 Apr 1;41(6):3819-32. doi: 10.1093/nar/gkt063. Epub 2013 Feb 7.

38.

hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.

Chapat C, Kolytcheff C, Le Romancer M, Auboeuf D, De La Grange P, Chettab K, Sentis S, Corbo L.

EMBO J. 2013 Mar 6;32(5):688-700. doi: 10.1038/emboj.2013.11. Epub 2013 Feb 5.

39.

Gene- and exon-expression profiling reveals an extensive LPS-induced response in immune cells in patients with cirrhosis.

Gandoura S, Weiss E, Rautou PE, Fasseu M, Gustot T, Lemoine F, Hurtado-Nedelec M, Hego C, Vadrot N, Elkrief L, Lettéron P, Tellier Z, Pocidalo MA, Valla D, Lebrec D, Groyer A, Monteiro RC, de la Grange P, Moreau R.

J Hepatol. 2013 May;58(5):936-48. doi: 10.1016/j.jhep.2012.12.025. Epub 2013 Jan 12.

PMID:
23321315
40.

The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling.

Moreira Sousa C, McGuire JR, Thion MS, Gentien D, de la Grange P, Tezenas du Montcel S, Vincent-Salomon A, Durr A, Humbert S.

EMBO Mol Med. 2013 Feb;5(2):309-25. doi: 10.1002/emmm.201201546. Epub 2013 Jan 9.

41.

Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F.

Wang E, Aslanzadeh V, Papa F, Zhu H, de la Grange P, Cambi F.

PLoS One. 2012;7(12):e51266. doi: 10.1371/journal.pone.0051266. Epub 2012 Dec 17.

42.

TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs.

Ballarino M, Jobert L, Dembélé D, de la Grange P, Auboeuf D, Tora L.

Oncogene. 2013 Sep 26;32(39):4646-55. doi: 10.1038/onc.2012.490. Epub 2012 Nov 5.

PMID:
23128393
43.

Lipocalin 2, the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.

Gaudineau B, Fougère M, Guaddachi F, Lemoine F, de la Grange P, Jauliac S.

J Cell Sci. 2012 Oct 1;125(Pt 19):4475-86. doi: 10.1242/jcs.099879. Epub 2012 Jul 5.

44.

A transcriptome signature of endothelial lymphatic cells coexists with the chronic oxidative stress signature in radiation-induced post-radiotherapy breast angiosarcomas.

Hadj-Hamou NS, Laé M, Almeida A, de la Grange P, Kirova Y, Sastre-Garau X, Malfoy B.

Carcinogenesis. 2012 Jul;33(7):1399-405. doi: 10.1093/carcin/bgs155. Epub 2012 Apr 24.

PMID:
22532251
45.

Sperm transcriptome profiling in oligozoospermia.

Montjean D, De La Grange P, Gentien D, Rapinat A, Belloc S, Cohen-Bacrie P, Menezo Y, Benkhalifa M.

J Assist Reprod Genet. 2012 Jan;29(1):3-10. doi: 10.1007/s10815-011-9644-3. Epub 2011 Oct 12.

46.

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

Fugier C, Klein AF, Hammer C, Vassilopoulos S, Ivarsson Y, Toussaint A, Tosch V, Vignaud A, Ferry A, Messaddeq N, Kokunai Y, Tsuburaya R, de la Grange P, Dembele D, Francois V, Precigout G, Boulade-Ladame C, Hummel MC, Lopez de Munain A, Sergeant N, Laquerrière A, Thibault C, Deryckere F, Auboeuf D, Garcia L, Zimmermann P, Udd B, Schoser B, Takahashi MP, Nishino I, Bassez G, Laporte J, Furling D, Charlet-Berguerand N.

Nat Med. 2011 Jun;17(6):720-5. doi: 10.1038/nm.2374. Epub 2011 May 29.

PMID:
21623381
47.

Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.

Ramgolam K, Lauriol J, Lalou C, Lauden L, Michel L, de la Grange P, Khatib AM, Aoudjit F, Charron D, Alcaide-Loridan C, Al-Daccak R.

PLoS One. 2011 Apr 15;6(4):e18784. doi: 10.1371/journal.pone.0018784.

48.

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB.

Llorian M, Schwartz S, Clark TA, Hollander D, Tan LY, Spellman R, Gordon A, Schweitzer AC, de la Grange P, Ast G, Smith CW.

Nat Struct Mol Biol. 2010 Sep;17(9):1114-23. doi: 10.1038/nsmb.1881. Epub 2010 Aug 15.

49.

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

Dutertre M, Gratadou L, Dardenne E, Germann S, Samaan S, Lidereau R, Driouch K, de la Grange P, Auboeuf D.

Cancer Res. 2010 May 1;70(9):3760-70. doi: 10.1158/0008-5472.CAN-09-3988. Epub 2010 Apr 20.

50.

The YTH domain is a novel RNA binding domain.

Zhang Z, Theler D, Kaminska KH, Hiller M, de la Grange P, Pudimat R, Rafalska I, Heinrich B, Bujnicki JM, Allain FH, Stamm S.

J Biol Chem. 2010 May 7;285(19):14701-10. doi: 10.1074/jbc.M110.104711. Epub 2010 Feb 18.

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