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Items: 1 to 50 of 73

1.

Reactive Oxygen Species Production Is a Major Factor Directing the Postantibiotic Effect of Fluoroquinolones in Streptococcus pneumoniae.

García MT, Valenzuela MV, Ferrándiz MJ, de la Campa AG.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00737-19. doi: 10.1128/AAC.00737-19. Print 2019 Aug.

PMID:
31160286
2.

Boldine-Derived Alkaloids Inhibit the Activity of DNA Topoisomerase I and Growth of Mycobacterium tuberculosis.

García MT, Carreño D, Tirado-Vélez JM, Ferrándiz MJ, Rodrigues L, Gracia B, Amblar M, Ainsa JA, de la Campa AG.

Front Microbiol. 2018 Jul 24;9:1659. doi: 10.3389/fmicb.2018.01659. eCollection 2018.

3.

An Uncharacterized Member of the Gls24 Protein Superfamily Is a Putative Sensor of Essential Amino Acid Availability in Streptococcus pneumoniae.

Ferrándiz MJ, Cercenado MI, Domenech M, Tirado-Vélez JM, Escolano-Martínez MS, Yuste J, García E, de la Campa AG, Martín-Galiano AJ.

Microb Ecol. 2019 Feb;77(2):471-487. doi: 10.1007/s00248-018-1218-9. Epub 2018 Jul 5.

PMID:
29978356
4.

HU of Streptococcus pneumoniae Is Essential for the Preservation of DNA Supercoiling.

Ferrándiz MJ, Carreño D, Ayora S, de la Campa AG.

Front Microbiol. 2018 Mar 19;9:493. doi: 10.3389/fmicb.2018.00493. eCollection 2018.

5.

Upregulation of the PatAB Transporter Confers Fluoroquinolone Resistance to Streptococcus pseudopneumoniae.

Alvarado M, Martín-Galiano AJ, Ferrándiz MJ, Zaballos Á, de la Campa AG.

Front Microbiol. 2017 Oct 26;8:2074. doi: 10.3389/fmicb.2017.02074. eCollection 2017.

6.

The Transcriptome of Streptococcus pneumoniae Induced by Local and Global Changes in Supercoiling.

de la Campa AG, Ferrándiz MJ, Martín-Galiano AJ, García MT, Tirado-Vélez JM.

Front Microbiol. 2017 Jul 31;8:1447. doi: 10.3389/fmicb.2017.01447. eCollection 2017. Review.

7.

Bridging Chromosomal Architecture and Pathophysiology of Streptococcus pneumoniae.

Martín-Galiano AJ, Ferrándiz MJ, de la Campa AG.

Genome Biol Evol. 2017 Feb 1;9(2):350-361. doi: 10.1093/gbe/evw299.

8.

Absence of tmRNA Has a Protective Effect against Fluoroquinolones in Streptococcus pneumoniae.

Brito L, Wilton J, Ferrándiz MJ, Gómez-Sanz A, de la Campa AG, Amblar M.

Front Microbiol. 2017 Jan 10;7:2164. doi: 10.3389/fmicb.2016.02164. eCollection 2016.

9.

An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene.

Ferrándiz MJ, Martín-Galiano AJ, Arnanz C, Camacho-Soguero I, Tirado-Vélez JM, de la Campa AG.

Nucleic Acids Res. 2016 Sep 6;44(15):7292-303. doi: 10.1093/nar/gkw602. Epub 2016 Jul 4.

10.

DiiA is a novel dimorphic cell wall protein of Streptococcus pneumoniae involved in invasive disease.

Escolano-Martínez MS, Domenech A, Yuste J, Cercenado MI, Ardanuy C, Liñares J, de la Campa AG, Martin-Galiano AJ.

J Infect. 2016 Jul;73(1):71-81. doi: 10.1016/j.jinf.2016.04.010. Epub 2016 Apr 20.

PMID:
27105656
11.

A Novel Typing Method for Streptococcus pneumoniae Using Selected Surface Proteins.

Domenech A, Moreno J, Ardanuy C, Liñares J, de la Campa AG, Martin-Galiano AJ.

Front Microbiol. 2016 Mar 31;7:420. doi: 10.3389/fmicb.2016.00420. eCollection 2016.

12.

Reactive Oxygen Species Contribute to the Bactericidal Effects of the Fluoroquinolone Moxifloxacin in Streptococcus pneumoniae.

Ferrándiz MJ, Martín-Galiano AJ, Arnanz C, Zimmerman T, de la Campa AG.

Antimicrob Agents Chemother. 2015 Nov 2;60(1):409-17. doi: 10.1128/AAC.02299-15. Print 2016 Jan.

13.

Identification of Haemophilus haemolyticus in clinical samples and characterization of their mechanisms of antimicrobial resistance.

Marti S, Puig C, de la Campa AG, Tirado-Velez JM, Tubau F, Domenech A, Calatayud L, Garcia-Somoza D, Ayats J, Liñares J, Ardanuy C.

J Antimicrob Chemother. 2016 Jan;71(1):80-4. doi: 10.1093/jac/dkv307. Epub 2015 Oct 15.

PMID:
26472767
14.

Molecular characterization of fluoroquinolone resistance in nontypeable Haemophilus influenzae clinical isolates.

Puig C, Tirado-Vélez JM, Calatayud L, Tubau F, Garmendia J, Ardanuy C, Marti S, de la Campa AG, Liñares J.

Antimicrob Agents Chemother. 2015 Jan;59(1):461-6. doi: 10.1128/AAC.04005-14. Epub 2014 Nov 10.

15.

Spread of Streptococcus pneumoniae serotype 8-ST63 multidrug-resistant recombinant Clone, Spain.

Ardanuy C, de la Campa AG, García E, Fenoll A, Calatayud L, Cercenado E, Pérez-Trallero E, Bouza E, Liñares J.

Emerg Infect Dis. 2014 Nov;20(11):1848-56. doi: 10.3201/eid2011.131215.

16.

Inspecting the potential physiological and biomedical value of 44 conserved uncharacterised proteins of Streptococcus pneumoniae.

Martín-Galiano AJ, Yuste J, Cercenado MI, de la Campa AG.

BMC Genomics. 2014 Aug 5;15:652. doi: 10.1186/1471-2164-15-652.

17.

Role of global and local topology in the regulation of gene expression in Streptococcus pneumoniae.

Ferrándiz MJ, Arnanz C, Martín-Galiano AJ, Rodríguez-Martín C, de la Campa AG.

PLoS One. 2014 Jul 14;9(7):e101574. doi: 10.1371/journal.pone.0101574. eCollection 2014.

18.

Induction of prophages by fluoroquinolones in Streptococcus pneumoniae: implications for emergence of resistance in genetically-related clones.

López E, Domenech A, Ferrándiz MJ, Frias MJ, Ardanuy C, Ramirez M, García E, Liñares J, de la Campa AG.

PLoS One. 2014 Apr 9;9(4):e94358. doi: 10.1371/journal.pone.0094358. eCollection 2014.

19.

Fluoroquinolone-resistant pneumococci: dynamics of serotypes and clones in Spain in 2012 compared with those from 2002 and 2006.

Domenech A, Tirado-Vélez JM, Fenoll A, Ardanuy C, Yuste J, Liñares J, de la Campa AG.

Antimicrob Agents Chemother. 2014;58(4):2393-9. doi: 10.1128/AAC.02669-13. Epub 2014 Feb 10.

20.

The fluoroquinolone levofloxacin triggers the transcriptional activation of iron transport genes that contribute to cell death in Streptococcus pneumoniae.

Ferrándiz MJ, de la Campa AG.

Antimicrob Agents Chemother. 2014;58(1):247-57. doi: 10.1128/AAC.01706-13. Epub 2013 Oct 21.

21.

Some pneumococcal serotypes are more frequently associated with relapses of acute exacerbations in COPD patients.

Domenech A, Ardanuy C, Pallares R, Grau I, Santos S, De la Campa AG, Liñares J.

PLoS One. 2013;8(3):e59027. doi: 10.1371/journal.pone.0059027. Epub 2013 Mar 11.

22.

Characterization of recombinant fluoroquinolone-resistant pneumococcus-like isolates.

Balsalobre L, Ortega M, de la Campa AG.

Antimicrob Agents Chemother. 2013 Jan;57(1):254-60. doi: 10.1128/AAC.01357-12. Epub 2012 Oct 31.

23.

Pneumococci can persistently colonize adult patients with chronic respiratory disease.

Domenech A, Ardanuy C, Balsalobre L, Marti S, Calatayud L, De la Campa AG, Brueggemann AB, Liñares J.

J Clin Microbiol. 2012 Dec;50(12):4047-53. doi: 10.1128/JCM.02056-12. Epub 2012 Oct 10.

24.

Fluoroquinolone efflux in Streptococcus suis is mediated by SatAB and not by SmrA.

Escudero JA, San Millan A, Gutierrez B, Hidalgo L, La Ragione RM, AbuOun M, Galimand M, Ferrándiz MJ, Domínguez L, de la Campa AG, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2011 Dec;55(12):5850-60. doi: 10.1128/AAC.00498-11. Epub 2011 Sep 19.

25.

Trends of invasive serotype 6C pneumococci in Spain: emergence of a new lineage.

Rolo D, Fenoll A, Ardanuy C, Calatayud L, Cubero M, de la Campa AG, Liñares J.

J Antimicrob Chemother. 2011 Aug;66(8):1712-8. doi: 10.1093/jac/dkr193. Epub 2011 May 31.

PMID:
21628304
26.

Epidemiological and molecular aspects of rifampicin-resistant Staphylococcus aureus isolated from wounds, blood and respiratory samples.

Villar M, Marimón JM, García-Arenzana JM, de la Campa AG, Ferrándiz MJ, Pérez-Trallero E.

J Antimicrob Chemother. 2011 May;66(5):997-1000. doi: 10.1093/jac/dkr059. Epub 2011 Mar 2.

PMID:
21393177
27.

Nonoptimal DNA topoisomerases allow maintenance of supercoiling levels and improve fitness of Streptococcus pneumoniae.

Balsalobre L, Ferrándiz MJ, de Alba G, de la Campa AG.

Antimicrob Agents Chemother. 2011 Mar;55(3):1097-105. doi: 10.1128/AAC.00783-10. Epub 2010 Dec 20.

28.

New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae.

García MT, Blázquez MA, Ferrándiz MJ, Sanz MJ, Silva-Martín N, Hermoso JA, de la Campa AG.

J Biol Chem. 2011 Feb 25;286(8):6402-13. doi: 10.1074/jbc.M110.148148. Epub 2010 Dec 17.

29.

New species genetic approach to identify strains of mitis group streptococci that are donors of rifampin resistance to Streptococcus pneumoniae.

Ferrándiz MJ, Ardanuy C, Liñares J, Balsalobre L, García MT, de la Campa AG.

Antimicrob Agents Chemother. 2011 Jan;55(1):368-72. doi: 10.1128/AAC.00856-10. Epub 2010 Nov 1.

30.

The relBE2Spn toxin-antitoxin system of Streptococcus pneumoniae: role in antibiotic tolerance and functional conservation in clinical isolates.

Nieto C, Sadowy E, de la Campa AG, Hryniewicz W, Espinosa M.

PLoS One. 2010 Jun 23;5(6):e11289. doi: 10.1371/journal.pone.0011289.

31.

Evidence of localized prophage-host recombination in the lytA gene, encoding the major pneumococcal autolysin.

Morales M, García P, de la Campa AG, Liñares J, Ardanuy C, García E.

J Bacteriol. 2010 May;192(10):2624-32. doi: 10.1128/JB.01501-09. Epub 2010 Mar 19.

32.

The genome of Streptococcus pneumoniae is organized in topology-reacting gene clusters.

Ferrándiz MJ, Martín-Galiano AJ, Schvartzman JB, de la Campa AG.

Nucleic Acids Res. 2010 Jun;38(11):3570-81. doi: 10.1093/nar/gkq106. Epub 2010 Feb 21.

33.

Changes in fluoroquinolone-resistant Streptococcus pneumoniae after 7-valent conjugate vaccination, Spain.

de la Campa AG, Ardanuy C, Balsalobre L, Pérez-Trallero E, Marimón JM, Fenoll A, Liñares J.

Emerg Infect Dis. 2009 Jun;15(6):905-11. doi: 10.3201/eid1506.080684.

34.

Fitness of Streptococcus pneumoniae fluoroquinolone-resistant strains with topoisomerase IV recombinant genes.

Balsalobre L, de la Campa AG.

Antimicrob Agents Chemother. 2008 Mar;52(3):822-30. Epub 2007 Dec 26.

35.

First characterization of fluoroquinolone resistance in Streptococcus suis.

Escudero JA, San Millan A, Catalan A, de la Campa AG, Rivero E, Lopez G, Dominguez L, Moreno MA, Gonzalez-Zorn B.

Antimicrob Agents Chemother. 2007 Feb;51(2):777-82. Epub 2006 Nov 20.

36.

Molecular characterization of disease-associated streptococci of the mitis group that are optochin susceptible.

Balsalobre L, Hernández-Madrid A, Llull D, Martín-Galiano AJ, García E, Fenoll A, de la Campa AG.

J Clin Microbiol. 2006 Nov;44(11):4163-71. Epub 2006 Sep 13.

37.

Transcriptional analysis of the acid tolerance response in Streptococcus pneumoniae.

Martín-Galiano AJ, Overweg K, Ferrándiz MJ, Reuter M, Wells JM, de la Campa AG.

Microbiology. 2005 Dec;151(Pt 12):3935-46.

PMID:
16339938
38.

Clinical Isolates of the Spain14-5 clone of Streptococcus pneumoniae carry a recombinant rpoB gene.

Ferrándiz MJ, Pérez-Trallero E, Marimón JM, de la Campa AG.

Antimicrob Agents Chemother. 2005 Nov;49(11):4811-3. No abstract available.

39.

New mutations and horizontal transfer of rpoB among rifampin-resistant Streptococcus pneumoniae from four Spanish hospitals.

Ferrándiz MJ, Ardanuy C, Liñares J, García-Arenzana JM, Cercenado E, Fleites A, de la Campa AG; Spanish Pneumococcal Infection Study Network.

Antimicrob Agents Chemother. 2005 Jun;49(6):2237-45.

40.

Fluoroquinolone resistance in penicillin-resistant Streptococcus pneumoniae clones, Spain.

de la Campa AG, Balsalobre L, Ardanuy C, Fenoll A, Pérez-Trallero E, Liñares J; Spanish Pneumococcal Infection Study Network G03/103.

Emerg Infect Dis. 2004 Oct;10(10):1751-9.

41.

Relationship between codon biased genes, microarray expression values and physiological characteristics of Streptococcus pneumoniae.

Martín-Galiano AJ, Wells JM, de la Campa AG.

Microbiology. 2004 Jul;150(Pt 7):2313-25.

PMID:
15256573
42.

[Streptococcus salivarius meningitis after spinal anesthesia].

Conangla G, Rodríguez L, Alonso-Tarrés C, Avila A, de la Campa AG.

Neurologia. 2004 Jul-Aug;19(6):331-3. Spanish.

PMID:
15199424
43.

Levofloxacin treatment failure in Haemophilus influenzae pneumonia.

Bastida T, Pérez-Vázquez M, Campos J, Cortés-Lletget MC, Román F, Tubau F, de la Campa AG, Alonso-Tarrés C.

Emerg Infect Dis. 2003 Nov;9(11):1475-8.

44.

Genetic characterization of optochin-susceptible viridans group streptococci.

Martín-Galiano AJ, Balsalobre L, Fenoll A, de la Campa AG.

Antimicrob Agents Chemother. 2003 Oct;47(10):3187-94.

45.

Viridans group streptococci are donors in horizontal transfer of topoisomerase IV genes to Streptococcus pneumoniae.

Balsalobre L, Ferrándiz MJ, Liñares J, Tubau F, de la Campa AG.

Antimicrob Agents Chemother. 2003 Jul;47(7):2072-81.

46.

Genetic characterization of fluoroquinolone-resistant Streptococcus pneumoniae strains isolated during ciprofloxacin therapy from a patient with bronchiectasis.

de la Campa AG, Ferrandiz MJ, Tubau F, Pallarés R, Manresa F, Liñares J.

Antimicrob Agents Chemother. 2003 Apr;47(4):1419-22.

47.

High-efficiency generation of antibiotic-resistant strains of Streptococcus pneumoniae by PCR and transformation.

Martín-Galiano AJ, de la Campa AG.

Antimicrob Agents Chemother. 2003 Apr;47(4):1257-61.

48.

The membrane-associated F(0)F(1) ATPase is essential for the viability of Streptococcus pneumoniae.

Ferrándiz MJ, de la Campa AG.

FEMS Microbiol Lett. 2002 Jun 18;212(1):133-8.

49.

Mefloquine and new related compounds target the F(0) complex of the F(0)F(1) H(+)-ATPase of Streptococcus pneumoniae.

Martín-Galiano AJ, Gorgojo B, Kunin CM, de la Campa AG.

Antimicrob Agents Chemother. 2002 Jun;46(6):1680-7.

50.

The promoter of the operon encoding the F0F1 ATPase of Streptococcus pneumoniae is inducible by pH.

Martín-Galiano AJ, Ferrándiz MJ, de la Campa AG.

Mol Microbiol. 2001 Sep;41(6):1327-38.

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