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Evaluation of the primary biliary cholangitis-related serologic profile in a large cohort of Belgian systemic sclerosis patients.

Florin L, Rubben K, Vanhaecke A, Devreese K, De Keyser F, Smith V, Bonroy C.

Clin Chem Lab Med. 2020 Feb 25;58(3):416-423. doi: 10.1515/cclm-2019-0655.


Pitfalls in the detection of myositis specific antibodies by lineblot in clinically suspected idiopathic inflammatory myopathy.

Piette Y, De Sloovere M, Vandendriessche S, Dehoorne J, De Bleecker JL, Van Praet L, Vander Mijnsbrugge AS, De Schepper S, Jacques P, De Keyser F, Smith V, Bonroy C.

Clin Exp Rheumatol. 2020 Mar-Apr;38(2):212-219. Epub 2019 Jul 4.


Testing a model of auditory hallucinations: the role of negative emotions and cognitive resources.

Laloyaux J, De Keyser F, Pinchard A, Della Libera C, Larøi F.

Cogn Neuropsychiatry. 2019 Jul;24(4):256-274. doi: 10.1080/13546805.2019.1629895. Epub 2019 Jun 12.


A prospective, longitudinal study evaluating the baseline six-minute walk test as an individual reference value in systemic sclerosis patients.

Vandecasteele E, Melsens K, De Keyser F, De Pauw M, Deschepper E, Decuman S, Piette Y, Thevissen K, Brusselle G, Smith V.

Clin Exp Rheumatol. 2018 Jul-Aug;36 Suppl 113(4):95-101. Epub 2018 Aug 28.


Is laser speckle contrast analysis (LASCA) the new kid on the block in systemic sclerosis? A systematic literature review and pilot study to evaluate reliability of LASCA to measure peripheral blood perfusion in scleroderma patients.

Cutolo M, Vanhaecke A, Ruaro B, Deschepper E, Ickinger C, Melsens K, Piette Y, Trombetta AC, De Keyser F, Smith V; EULAR Study Group on Microcirculation in Rheumatic Diseases.

Autoimmun Rev. 2018 Aug;17(8):775-780. doi: 10.1016/j.autrev.2018.01.023. Epub 2018 Jun 6. Review.


Nailfold capillaroscopy in systemic lupus erythematosus: A systematic review and critical appraisal.

Cutolo M, Melsens K, Wijnant S, Ingegnoli F, Thevissen K, De Keyser F, Decuman S, Müller-Ladner U, Piette Y, Riccieri V, Ughi N, Vandecasteele E, Vanhaecke A, Smith V.

Autoimmun Rev. 2018 Apr;17(4):344-352. doi: 10.1016/j.autrev.2017.11.025. Epub 2018 Feb 8. Review.


Reliability of simple capillaroscopic definitions in describing capillary morphology in rheumatic diseases.

Cutolo M, Melsens K, Herrick AL, Foeldvari I, Deschepper E, De Keyser F, Distler O, Ingegnoli F, Mostmans Y, Müller-Ladner U, Pizzorni C, Riccieri V, Ruaro B, Sulli A, Trombetta AC, Vanhaecke A, Smith V; EULAR Study Group on Microcirculation in Rheumatic Diseases.

Rheumatology (Oxford). 2018 Apr 1;57(4):757-759. doi: 10.1093/rheumatology/kex460. Review. No abstract available.


Two years follow-up of an open-label pilot study of treatment with rituximab in patients with early diffuse cutaneous systemic sclerosis.

Melsens K, Vandecasteele E, Deschepper E, Badot V, Blockmans D, Brusselle G, De Langhe E, De Pauw M, Debusschere C, Decuman S, Deroo L, Houssiau F, Lenaerts J, Piette Y, Thevissen K, Vanthuyne M, Westhovens R, Wijnant S, De Keyser F, Smith V.

Acta Clin Belg. 2018 Apr;73(2):119-125. doi: 10.1080/17843286.2017.1372244. Epub 2017 Sep 11.


The role of endothelial cells in the vasculopathy of systemic sclerosis: A systematic review.

Mostmans Y, Cutolo M, Giddelo C, Decuman S, Melsens K, Declercq H, Vandecasteele E, De Keyser F, Distler O, Gutermuth J, Smith V.

Autoimmun Rev. 2017 Aug;16(8):774-786. doi: 10.1016/j.autrev.2017.05.024. Epub 2017 May 29. Review.


Screening for pulmonary arterial hypertension in an unselected prospective systemic sclerosis cohort.

Vandecasteele E, Drieghe B, Melsens K, Thevissen K, De Pauw M, Deschepper E, Decuman S, Bonroy C, Piette Y, De Keyser F, Brusselle G, Smith V.

Eur Respir J. 2017 May 11;49(5). pii: 1602275. doi: 10.1183/13993003.02275-2016. Print 2017 May.


Six-minute walk test in or out in evaluation of systemic sclerosis patients?

Vandecasteele E, Thevissen K, Melsens K, De Keyser F, De Pauw M, Deschepper E, Decuman S, Piette Y, Brusselle G, Smith V.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):122-129. Epub 2017 Feb 15.


Assessment of sensitivity to change of the European Scleroderma Study Group activity index.

Melsens K, De Keyser F, Decuman S, Brusselle G, De Pauw M, Deschepper E, De Wilde K, Elewaut D, Piette Y, Vandecasteele E, Smith V.

Clin Exp Rheumatol. 2016 Sep-Oct;34 Suppl 100(5):148-151. Epub 2016 Jul 18.


Disease activity indices in systemic sclerosis: a systematic literature review.

Melsens K, De Keyser F, Decuman S, Piette Y, Vandecasteele E, Smith V.

Clin Exp Rheumatol. 2016 Sep-Oct;34 Suppl 100(5):186-192. Epub 2016 Jul 6. Review.


Stabilization of Microcirculation in Patients with Early Systemic Sclerosis with Diffuse Skin Involvement following Rituximab Treatment: An Open-label Study.

Smith V, Pizzorni C, Riccieri V, Decuman S, Brusselle G, DE Pauw M, Deschepper E, Piette Y, Ruaro B, Sulli A, Vandecasteele E, Melsens K, DE Keyser F, Cutolo M.

J Rheumatol. 2016 May;43(5):995-6. doi: 10.3899/jrheum.151018. No abstract available.


Nailfold Capillaroscopy and Clinical Applications in Systemic Sclerosis.

Smith V, Thevissen K, Trombetta AC, Pizzorni C, Ruaro B, Piette Y, Paolino S, De Keyser F, Sulli A, Melsens K, Cutolo M; EULAR Study Group on Microcirculation in Rheumatic Diseases.

Microcirculation. 2016 Jul;23(5):364-72. doi: 10.1111/micc.12281. Review.


The heart and pulmonary arterial hypertension in systemic sclerosis.

Vandecasteele EH, De Pauw M, Brusselle G, Decuman S, Piette Y, De Keyser F, Smith V.

Acta Clin Belg. 2016 Feb;71(1):1-18. doi: 10.1080/17843286.2015.1108538. Epub 2016 Feb 5. Review.


Six-minute walk test in systemic sclerosis: A systematic review and meta-analysis.

Vandecasteele E, De Pauw M, De Keyser F, Decuman S, Deschepper E, Piette Y, Brusselle G, Smith V.

Int J Cardiol. 2016 Jun 1;212:265-73. doi: 10.1016/j.ijcard.2016.03.084. Epub 2016 Mar 25. Review.


Reliability of the quantitative assessment of peripheral blood perfusion by laser speckle contrast analysis in a systemic sclerosis cohort.

Lambrecht V, Cutolo M, De Keyser F, Decuman S, Ruaro B, Sulli A, Deschepper E, Smith V.

Ann Rheum Dis. 2016 Jun;75(6):1263-4. doi: 10.1136/annrheumdis-2015-208857. Epub 2016 Mar 22. No abstract available.


An EULAR study group pilot study on reliability of simple capillaroscopic definitions to describe capillary morphology in rheumatic diseases.

Smith V, Beeckman S, Herrick AL, Decuman S, Deschepper E, De Keyser F, Distler O, Foeldvari I, Ingegnoli F, Müller-Ladner U, Riccieri V, Riemekasten G, Sulli A, Voskuyl A, Cutolo M; EULAR study group on microcirculation.

Rheumatology (Oxford). 2016 May;55(5):883-90. doi: 10.1093/rheumatology/kev441. Epub 2016 Feb 3.


Comparison of the Belgian Rheumatoid Arthritis Disability Assessment and Health Assessment Questionnaires as Tools to Predict the Need for Support Measures in Patients with Rheumatoid Arthritis.

Janssens X, Decuman S, De Keyser F; Belgian Rheumatoid Arthritis Disability Assessment study group.

PLoS One. 2016 Jan 22;11(1):e0146688. doi: 10.1371/journal.pone.0146688. eCollection 2016.


Specific Antinuclear Antibody Level Changes after B Cell Depletion Therapy in Systemic Sclerosis Are Associated with Improvement of Skin Thickening.

Bonroy C, Smith V, Deschepper E, De Keyser F, Devreese K.

J Rheumatol. 2016 Jan;43(1):247-9. doi: 10.3899/jrheum.150105. No abstract available. Erratum in: J Rheumatol. 2016 Mar;43(3):681.


Fuchs' Uveitis Syndrome: No Longer a Syndrome?

Kreps EO, Derveaux T, De Keyser F, Kestelyn P.

Ocul Immunol Inflamm. 2016 Jun;24(3):348-57. doi: 10.3109/09273948.2015.1005239. Epub 2015 Jul 29. Review.


Factors influencing the occupational trajectory of patients with systemic sclerosis: a qualitative study.

Decuman S, Smith V, Grypdonck M, De Keyser F, Verhaeghe S.

Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S26-30. Epub 2015 Mar 20.


Lupus anticoagulant-hypoprothrombinemia syndrome: report of two cases and review of the literature.

Mulliez SM, De Keyser F, Verbist C, Vantilborgh A, Wijns W, Beukinga I, Devreese KM.

Lupus. 2015 Jun;24(7):736-45. doi: 10.1177/0961203314558859. Epub 2014 Nov 12. Review.


Work participation in patients with systemic sclerosis: a systematic review.

Decuman S, Smith V, Verhaeghe ST, Van Hecke A, De Keyser F.

Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-206-13. Epub 2014 Nov 5. Review.


Assessment of activity limitations with the health assessment questionnaire predicts the need for support measures in patients with rheumatoid arthritis: a multicenter observational study.

Janssens X, Decuman S, De Keyser F; Belgian Rheumatoid Arthritis Disability Assessment Study Group.

PLoS One. 2014 Sep 4;9(9):e106749. doi: 10.1371/journal.pone.0106749. eCollection 2014.


Longterm followup of rituximab therapy in patients with rheumatoid arthritis: results from the Belgian MabThera in Rheumatoid Arthritis registry.

De Keyser F, Hoffman I, Durez P, Kaiser MJ, Westhovens R; MIRA Study Group.

J Rheumatol. 2014 Sep;41(9):1761-5. doi: 10.3899/jrheum.131279. Epub 2014 Aug 15.


Tuberculin skin test versus interferon-gamma release assays for the diagnosis of tuberculosis infection.

De Keyser E, De Keyser F, De Baets F.

Acta Clin Belg. 2014 Oct;69(5):358-66. doi: 10.1179/2295333714Y.0000000043. Epub 2014 Jul 14.


Ten-year followup of infliximab therapy in rheumatoid arthritis patients with severe, longstanding refractory disease: a cohort study.

De Keyser F, De Kock J, Leroi H, Durez P, Westhovens R; Infliximab EAP Study Group.

J Rheumatol. 2014 Jul;41(7):1276-81. doi: 10.3899/jrheum.131270. Epub 2014 Jun 1.


Relevance of different results of different anti-double-stranded DNA assays in reporting clinical studies: comment on the article by Petri et al.

Bonroy C, Verfaillie C, De Witte E, De Keyser F.

Arthritis Rheumatol. 2014 Feb;66(2):479-80. doi: 10.1002/art.38252. No abstract available.


Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development.

Lambrecht S, Smith V, De Wilde K, Coudenys J, Decuman S, Deforce D, De Keyser F, Elewaut D.

Arthritis Rheumatol. 2014 Feb;66(2):418-27. doi: 10.1002/art.38241.


Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis.

van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifano G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, Saxne T, DiMarzio M, Wuttge D, Agarwal SK, Reveille JD, Assassi S, Mayes M, Deng Y, Drenth JP, de Graaf J, den Heijer M, Kallenberg CG, Bijl M, Loof A, van den Berg WB, Joosten LA, Smith V, de Keyser F, Scorza R, Lunardi C, van Riel PL, Vonk M, van Heerde W, Meller S, Homey B, Beretta L, Roest M, Trojanowska M, Lafyatis R, Radstake TR.

N Engl J Med. 2014 Jan 30;370(5):433-43. doi: 10.1056/NEJMoa1114576. Epub 2013 Dec 18.


Nailfold capillaroscopy for prediction of novel future severe organ involvement in systemic sclerosis.

Smith V, Riccieri V, Pizzorni C, Decuman S, Deschepper E, Bonroy C, Sulli A, Piette Y, De Keyser F, Cutolo M.

J Rheumatol. 2013 Dec;40(12):2023-8. doi: 10.3899/jrheum.130528. Epub 2013 Oct 15.


Cancer risk in immune-mediated inflammatory diseases (IMID).

Beyaert R, Beaugerie L, Van Assche G, Brochez L, Renauld JC, Viguier M, Cocquyt V, Jerusalem G, Machiels JP, Prenen H, Masson P, Louis E, De Keyser F.

Mol Cancer. 2013 Aug 29;12(1):98. doi: 10.1186/1476-4598-12-98. Review.


The integration of the detection of systemic sclerosis-associated antibodies in a routine laboratory setting: comparison of different strategies.

Bonroy C, Smith V, Van Steendam K, Van Praet J, Deforce D, Devreese K, De Keyser F.

Clin Chem Lab Med. 2013 Nov;51(11):2151-60. doi: 10.1515/cclm-2013-0211.


The influence of ageing on the development and management of rheumatoid arthritis.

Boots AM, Maier AB, Stinissen P, Masson P, Lories RJ, De Keyser F.

Nat Rev Rheumatol. 2013 Oct;9(10):604-13. doi: 10.1038/nrrheum.2013.92. Epub 2013 Jun 18. Review.


Automated indirect immunofluorescence antinuclear antibody analysis is a standardized alternative for visual microscope interpretation.

Bonroy C, Verfaillie C, Smith V, Persijn L, De Witte E, De Keyser F, Devreese K.

Clin Chem Lab Med. 2013 Sep;51(9):1771-9. doi: 10.1515/cclm-2013-0016. Erratum in: Clin Chem Lab Med. 2014 Nov;52(11):1677.


Optimal approaches to data collection and analysis of potential immune mediated disorders in clinical trials of new vaccines.

Tavares Da Silva F, De Keyser F, Lambert PH, Robinson WH, Westhovens R, Sindic C.

Vaccine. 2013 Apr 3;31(14):1870-6. doi: 10.1016/j.vaccine.2013.01.042. Epub 2013 Feb 4.


Two-year results of an open pilot study of a 2-treatment course with rituximab in patients with early systemic sclerosis with diffuse skin involvement.

Smith V, Piette Y, van Praet JT, Decuman S, Deschepper E, Elewaut D, De Keyser F.

J Rheumatol. 2013 Jan;40(1):52-7. doi: 10.3899/jrheum.120778. Epub 2012 Nov 1.


The Belgian Systemic Sclerosis Cohort: correlations between disease severity scores, cutaneous subsets, and autoantibody profile.

Vanthuyne M, Smith V, De Langhe E, Van Praet J, Arat S, Depresseux G, Westhovens R, Blockmans D, Badot V, Cogan E, De Keyser F, Houssiau FA.

J Rheumatol. 2012 Nov;39(11):2127-33. doi: 10.3899/jrheum.120283. Epub 2012 Sep 15.


Quantification of IFNγ- and IL17-producing cells after stimulation with citrullinated proteins in healthy subjects and RA patients.

Van Steendam K, De Ceuleneer M, Tilleman K, Elewaut D, De Keyser F, Deforce D.

Rheumatol Int. 2013 Oct;33(10):2661-4. doi: 10.1007/s00296-012-2470-9. Epub 2012 Jul 24.


Fluoroenzymeimmunoassay to detect systemic sclerosis-associated antibodies: diagnostic performance and correlation with conventional techniques.

Bonroy C, Smith V, Van Steendam K, Van Praet J, Deforce D, Devreese K, De Keyser F.

Clin Exp Rheumatol. 2012 Sep-Oct;30(5):748-55. Epub 2012 Oct 17.


Management of inflammatory bowel disease in pregnancy.

Vermeire S, Carbonnel F, Coulie PG, Geenen V, Hazes JM, Masson PL, De Keyser F, Louis E.

J Crohns Colitis. 2012 Sep;6(8):811-23. doi: 10.1016/j.crohns.2012.04.009. Epub 2012 May 16. Review.


Optimization and diagnostic performance of a single multiparameter lineblot in the serological workup of systemic sclerosis.

Bonroy C, Van Praet J, Smith V, Van Steendam K, Mimori T, Deschepper E, Deforce D, Devreese K, De Keyser F.

J Immunol Methods. 2012 May 31;379(1-2):53-60. doi: 10.1016/j.jim.2012.03.001. Epub 2012 Mar 11.


Do worsening scleroderma capillaroscopic patterns predict future severe organ involvement? a pilot study.

Smith V, Decuman S, Sulli A, Bonroy C, Piettte Y, Deschepper E, de Keyser F, Cutolo M.

Ann Rheum Dis. 2012 Oct;71(10):1636-9. doi: 10.1136/annrheumdis-2011-200780. Epub 2012 Mar 8.


The association of illness perceptions with physical and mental health in systemic sclerosis patients: an exploratory study.

Arat S, Verschueren P, De Langhe E, Smith V, Vanthuyne M, Diya L, Van den Heede K, Blockmans D, De Keyser F, Houssiau FA, Westhovens R.

Musculoskeletal Care. 2012 Mar;10(1):18-28. doi: 10.1002/msc.223. Epub 2011 Nov 11.


The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis.

Martin JE, Carmona FD, Broen JC, Simeón CP, Vonk MC, Carreira P, Ríos-Fernández R, Espinosa G, Vicente-Rabaneda E, Tolosa C, García-Hernández FJ, Castellví I, Fonollosa V, González-Gay MA, Sáez-Comet L, Portales RG, de la Peña PG, Fernández-Castro M, Díaz B, Martínez-Estupiñán L, Coenen M, Voskuyl AE, Schuerwegh AJ, Vanthuyne M, Houssiau F, Smith V, de Keyser F, De Langhe E, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Palm Ø, Chee MM, van Laar JM, Denton C, Herrick A, Worthington J, Koeleman BP, Radstake TR, Fonseca C, Martín J; Spanish Scleroderma Group.

Genes Immun. 2012 Feb;13(2):191-6. doi: 10.1038/gene.2011.72. Epub 2011 Oct 20.


Work participation and work transition in patients with systemic sclerosis: a cross-sectional study.

Decuman S, Smith V, Verhaeghe S, Deschepper E, Vermeiren F, De Keyser F.

Rheumatology (Oxford). 2012 Feb;51(2):297-304. doi: 10.1093/rheumatology/ker288. Epub 2011 Oct 4.


Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use.

Hazes JM, Coulie PG, Geenen V, Vermeire S, Carbonnel F, Louis E, Masson P, De Keyser F.

Rheumatology (Oxford). 2011 Nov;50(11):1955-68. doi: 10.1093/rheumatology/ker302. Epub 2011 Sep 2. Review.

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