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Items: 1 to 50 of 71

1.

Predicting global killer whale population collapse from PCB pollution.

Desforges JP, Hall A, McConnell B, Rosing-Asvid A, Barber JL, Brownlow A, De Guise S, Eulaers I, Jepson PD, Letcher RJ, Levin M, Ross PS, Samarra F, Víkingson G, Sonne C, Dietz R.

Science. 2018 Sep 28;361(6409):1373-1376. doi: 10.1126/science.aat1953.

PMID:
30262502
2.

Effects of polychlorinated biphenyls (PCB) on California sea lion (Zalophus californianus) lymphocyte functions upon in vitro exposure.

Peñín I, Levin M, Acevedo-Whitehouse K, Jasperse L, Gebhard E, Gulland FMD, De Guise S.

Environ Res. 2018 Nov;167:708-717. doi: 10.1016/j.envres.2018.08.028. Epub 2018 Aug 24.

PMID:
30236520
3.

Comparative toxicity of Corexit® 9500, oil, and a Corexit®/oil mixture on the eastern oyster, Crassostrea virginica (Gmelin).

Jasperse L, Levin M, Tsantiris K, Smolowitz R, Perkins C, Ward JE, De Guise S.

Aquat Toxicol. 2018 Oct;203:10-18. doi: 10.1016/j.aquatox.2018.07.015. Epub 2018 Jul 20.

PMID:
30064050
4.

Combined effects of Deepwater Horizon crude oil and environmental stressors on Fundulus grandis embryos.

Rodgers ML, Jones ER, Klinkhamer C, Mahapatra CT, Serafin J, Bosker T, Perkins C, Griffitt RJ, De Guise S, Sepúlveda MS.

Environ Toxicol Chem. 2018 Jul;37(7):1916-1925. doi: 10.1002/etc.4153. Epub 2018 Jun 4.

PMID:
29663533
5.

T lymphocyte-proliferative responses of harbor seal (Phoca vitulina) peripheral blood mononuclear cells (PBMCs) exposed to pharmaceuticals in vitro.

Kleinert C, Lacaze E, Fortier M, Hammill M, De Guise S, Fournier M.

Mar Pollut Bull. 2018 Feb;127:225-234. doi: 10.1016/j.marpolbul.2017.12.001. Epub 2017 Dec 8.

PMID:
29475659
6.

Effects of Polar Bear and Killer Whale Derived Contaminant Cocktails on Marine Mammal Immunity.

Desforges JP, Levin M, Jasperse L, De Guise S, Eulaers I, Letcher RJ, Acquarone M, Nordøy E, Folkow LP, Hammer Jensen T, Grøndahl C, Bertelsen MF, St Leger J, Almunia J, Sonne C, Dietz R.

Environ Sci Technol. 2017 Oct 3;51(19):11431-11439. doi: 10.1021/acs.est.7b03532. Epub 2017 Sep 25.

PMID:
28876915
7.

Immunotoxic effects of single and combined pharmaceuticals exposure on a harbor seal (Phoca vitulina) B lymphoma cell line.

Kleinert C, Lacaze E, Mounier M, De Guise S, Fournier M.

Mar Pollut Bull. 2017 May 15;118(1-2):237-247. doi: 10.1016/j.marpolbul.2017.02.041. Epub 2017 Mar 2.

PMID:
28262249
8.

Saxitoxin increases phocine distemper virus replication upon in-vitro infection in harbor seal immune cells.

Bogomolni AL, Bass AL, Fire S, Jasperse L, Levin M, Nielsen O, Waring G, De Guise S.

Harmful Algae. 2016 Jan;51:89-96. doi: 10.1016/j.hal.2015.10.013. Epub 2015 Dec 14.

PMID:
28003064
9.

Immunomodulatory effects of exposure to polychlorinated biphenyls and perfluoroalkyl acids in East Greenland ringed seals (Pusa hispida).

Levin M, Gebhard E, Jasperse L, Desforges JP, Dietz R, Sonne C, Eulaers I, Covaci A, Bossi R, De Guise S.

Environ Res. 2016 Nov;151:244-250. doi: 10.1016/j.envres.2016.07.013. Epub 2016 Aug 6.

PMID:
27504872
10.

Immunotoxic effects of environmental pollutants in marine mammals.

Desforges JP, Sonne C, Levin M, Siebert U, De Guise S, Dietz R.

Environ Int. 2016 Jan;86:126-39. doi: 10.1016/j.envint.2015.10.007. Epub 2015 Nov 16. Review.

PMID:
26590481
11.

In Vitro Exposure of Harbor Seal Immune Cells to Aroclor 1260 Alters Phocine Distemper Virus Replication.

Bogomolni A, Frasca S Jr, Levin M, Matassa K, Nielsen O, Waring G, De Guise S.

Arch Environ Contam Toxicol. 2016 Jan;70(1):121-32. doi: 10.1007/s00244-015-0178-z. Epub 2015 Jul 4.

PMID:
26142119
12.

Development of a one-step duplex RT-qPCR for the quantification of phocine distemper virus.

Bogomolni AL, Frasca S Jr, Matassa KA, Nielsen O, Rogers K, De Guise S.

J Wildl Dis. 2015 Apr;51(2):454-65. doi: 10.7589/2014-05-142. Epub 2015 Feb 3.

PMID:
25647591
13.

Cetacean morbillivirus: current knowledge and future directions.

Van Bressem MF, Duignan PJ, Banyard A, Barbieri M, Colegrove KM, De Guise S, Di Guardo G, Dobson A, Domingo M, Fauquier D, Fernandez A, Goldstein T, Grenfell B, Groch KR, Gulland F, Jensen BA, Jepson PD, Hall A, Kuiken T, Mazzariol S, Morris SE, Nielsen O, Raga JA, Rowles TK, Saliki J, Sierra E, Stephens N, Stone B, Tomo I, Wang J, Waltzek T, Wellehan JF.

Viruses. 2014 Dec 22;6(12):5145-81. doi: 10.3390/v6125145. Review.

14.

Phocine distemper virus: current knowledge and future directions.

Duignan PJ, Van Bressem MF, Baker JD, Barbieri M, Colegrove KM, De Guise S, de Swart RL, Di Guardo G, Dobson A, Duprex WP, Early G, Fauquier D, Goldstein T, Goodman SJ, Grenfell B, Groch KR, Gulland F, Hall A, Jensen BA, Lamy K, Matassa K, Mazzariol S, Morris SE, Nielsen O, Rotstein D, Rowles TK, Saliki JT, Siebert U, Waltzek T, Wellehan JF.

Viruses. 2014 Dec 22;6(12):5093-134. doi: 10.3390/v6125093. Review.

15.

Validation of a commercial canine assay kit to measure pinniped cytokines.

Levin M, Romano T, Matassa K, De Guise S.

Vet Immunol Immunopathol. 2014 Jul 15;160(1-2):90-6. doi: 10.1016/j.vetimm.2014.04.001. Epub 2014 May 1.

PMID:
24845148
16.

Response to comment on health of common bottlenose dolphins (Tursiops truncatus) in Barataria Bay, Louisiana following the deepwater horizon oil spill.

Schwacke LH, Smith CR, Townsend FI, Wells RS, Hart LB, Balmer BC, Collier TK, De Guise S, Fry MM, Guillette LJ Jr, Lamb SV, Lane SM, McFee WE, Place NJ, Tumlin MC, Ylitalo GM, Zolman ES, Rowles TK.

Environ Sci Technol. 2014 Apr 1;48(7):4209-11. doi: 10.1021/es5009278. Epub 2014 Mar 13. No abstract available.

PMID:
24625036
17.

Health of common bottlenose dolphins ( Tursiops truncatus ) in Barataria Bay, Louisiana, following the deepwater horizon oil spill.

Schwacke LH, Smith CR, Townsend FI, Wells RS, Hart LB, Balmer BC, Collier TK, De Guise S, Fry MM, Guillette LJ Jr, Lamb SV, Lane SM, McFee WE, Place NJ, Tumlin MC, Ylitalo GM, Zolman ES, Rowles TK.

Environ Sci Technol. 2014;48(1):93-103. doi: 10.1021/es403610f. Epub 2013 Dec 18. Erratum in: Environ Sci Technol. 2014 Sep 2;48(17):10528.

PMID:
24350796
18.

Brucella sp. vertebral osteomyelitis with intercurrent fatal Staphylococcus aureus toxigenic enteritis in a bottlenose dolphin (Tursiops truncatus).

Goertz CE, Frasca S Jr, Bohach GA, Cowan DF, Buck JD, French RA, De Guise S, Maratea J, Hinckley L, Ewalt D, Schlievert PM, Karst SM, Deobald CF, St Aubin DJ, Dunn JL.

J Vet Diagn Invest. 2011 Jul;23(4):845-51. doi: 10.1177/1040638711407683. Epub 2011 Jun 15.

19.

Anaemia, hypothyroidism and immune suppression associated with polychlorinated biphenyl exposure in bottlenose dolphins (Tursiops truncatus).

Schwacke LH, Zolman ES, Balmer BC, De Guise S, George RC, Hoguet J, Hohn AA, Kucklick JR, Lamb S, Levin M, Litz JA, McFee WE, Place NJ, Townsend FI, Wells RS, Rowles TK.

Proc Biol Sci. 2012 Jan 7;279(1726):48-57. doi: 10.1098/rspb.2011.0665. Epub 2011 May 25.

20.

Comparative hepatic microsomal biotransformation of selected PBDEs, including decabromodiphenyl ether, and decabromodiphenyl ethane flame retardants in Arctic marine-feeding mammals.

McKinney MA, Dietz R, Sonne C, De Guise S, Skirnisson K, Karlsson K, Steingrímsson E, Letcher RJ.

Environ Toxicol Chem. 2011 Jul;30(7):1506-14. doi: 10.1002/etc.535. Epub 2011 Apr 27.

PMID:
21437940
21.

Immunomodulatory effects upon in vitro exposure of California sea lion and southern sea otter peripheral blood leukocytes to domoic acid.

Levin M, Joshi D, Draghi A 2nd, Gulland FM, Jessup D, De Guise S.

J Wildl Dis. 2010 Apr;46(2):541-50.

PMID:
20688647
22.

Eosinophilia and biotoxin exposure in bottlenose dolphins (Tursiops truncatus) from a coastal area impacted by repeated mortality events.

Schwacke LH, Twiner MJ, De Guise S, Balmer BC, Wells RS, Townsend FI, Rotstein DC, Varela RA, Hansen LJ, Zolman ES, Spradlin TR, Levin M, Leibrecht H, Wang Z, Rowles TK.

Environ Res. 2010 Aug;110(6):548-55. doi: 10.1016/j.envres.2010.05.003. Epub 2010 May 26.

PMID:
20537621
23.

Comparative sensitivity of harbour and grey seals to several environmental contaminants using in vitro exposure.

Dufresne MM, Frouin H, Pillet S, Lesage V, De Guise S, Fournier M.

Mar Pollut Bull. 2010 Mar;60(3):344-9. doi: 10.1016/j.marpolbul.2009.10.019. Epub 2009 Nov 28.

PMID:
19945719
24.

Immunomodulatory effects of domoic acid differ between in vivo and in vitro exposure in mice.

Levin M, Leibrecht H, Ryan J, Van Dolah F, De Guise S.

Mar Drugs. 2008;6(4):636-59. doi: 10.3390/md6040636. Epub 2008 Dec 22.

25.

Prevalence and ultrastructure of sarcocystis in American woodcock harvested in Connecticut.

Hiller BJ, Sidor IF, De Guise S, Barclay JS.

J Parasitol. 2007 Dec;93(6):1529-30. doi: 10.1645/GE-1248.1.

PMID:
18314707
26.

Effects of organochlorines, individually and in mixtures, on B-cell proliferation in marine mammals and mice.

Mori C, Morsey B, Levin M, Gorton TS, De Guise S.

J Toxicol Environ Health A. 2008;71(4):266-75. doi: 10.1080/15287390701612860.

PMID:
18253892
27.

A cDNA microarray for Crassostrea virginica and C. gigas.

Jenny MJ, Chapman RW, Mancia A, Chen YA, McKillen DJ, Trent H, Lang P, Escoubas JM, Bachere E, Boulo V, Liu ZJ, Gross PS, Cunningham C, Cupit PM, Tanguy A, Guo X, Moraga D, Boutet I, Huvet A, De Guise S, Almeida JS, Warr GW.

Mar Biotechnol (NY). 2007 Sep-Oct;9(5):577-91. Epub 2007 Aug 1.

PMID:
17668266
28.

Immunomodulatory effects of organochlorine mixtures upon in vitro exposure of peripheral blood leukocytes differ between free-ranging and captive southern sea otters (Enhydra lutris).

Levin M, Leibrecht H, Mori C, Jessup D, De Guise S.

Vet Immunol Immunopathol. 2007 Oct 15;119(3-4):269-77. Epub 2007 Jun 14.

PMID:
17629573
29.

Non-coplanar PCBs induce calcium mobilization in bottlenose dolphin and beluga whale, but not in mouse leukocytes.

Levin M, Morsey B, De Guise S.

J Toxicol Environ Health A. 2007 Jul;70(14):1220-31.

PMID:
17573636
30.

Chemical and biological pollution contribute to the immunological profiles of free-ranging harbor seals.

Mos L, Morsey B, Jeffries SJ, Yunker MB, Raverty S, De Guise S, Ross PS.

Environ Toxicol Chem. 2006 Dec;25(12):3110-7.

PMID:
17220078
31.

Modulation of the respiratory burst by organochlorine mixtures in marine mammals, humans, and mice.

Levin M, Morsey B, De Guise S.

J Toxicol Environ Health A. 2007 Jan;70(1):73-83.

PMID:
17162500
32.

Organohalogen contaminants and metabolites in beluga whale (Delphinapterus leucas) liver from two Canadian populations.

McKinney MA, De Guise S, Martineau D, Béland P, Lebeuf M, Letcher RJ.

Environ Toxicol Chem. 2006 May;25(5):1246-57.

PMID:
16704055
33.

Immunomodulatory effects of in vitro exposure to organochlorines on T-cell proliferation in marine mammals and mice.

Mori C, Morsey B, Levin M, Nambiar PR, De Guise S.

J Toxicol Environ Health A. 2006 Feb;69(3-4):283-302.

PMID:
16407088
34.

Biotransformation of polybrominated diphenyl ethers and polychlorinated biphenyls in beluga whale (Delphinapterus leucas) and rat mammalian model using an in vitro hepatic microsomal assay.

McKinney MA, De Guise S, Martineau D, Béland P, Arukwe A, Letcher RJ.

Aquat Toxicol. 2006 Apr 20;77(1):87-97. Epub 2005 Dec 2.

PMID:
16325935
35.

Non-coplanar PCB-mediated modulation of human leukocyte phagocytosis: a new mechanism for immunotoxicity.

Levin M, Morsey B, Mori C, Nambiar PR, De Guise S.

J Toxicol Environ Health A. 2005 Nov 26;68(22):1977-93.

PMID:
16263690
37.

PCBs and TCDD, alone and in mixtures, modulate marine mammal but not B6C3F1 mouse leukocyte phagocytosis.

Levin M, Morsey B, Mori C, Nambiar PR, De Guise S.

J Toxicol Environ Health A. 2005 Apr 23;68(8):635-56.

PMID:
15901092
38.

Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis.

Ilsley JN, Nakanishi M, Flynn C, Belinsky GS, De Guise S, Adib JN, Dobrowsky RT, Bonventre JV, Rosenberg DW.

Cancer Res. 2005 Apr 1;65(7):2636-43.

39.

Characterization and profiling of hepatic cytochromes P450 and phase II xenobiotic-metabolizing enzymes in beluga whales (Delphinapterus leucas) from the St. Lawrence River Estuary and the Canadian Arctic.

McKinney MA, Arukwe A, De Guise S, Martineau D, Béland P, Dallaire A, Lair S, Lebeuf M, Letcher RJ.

Aquat Toxicol. 2004 Jul 30;69(1):35-49.

PMID:
15210296
40.

Malathion immunotoxicity in the American lobster (Homarus americanus) upon experimental exposure.

De Guise S, Maratea J, Perkins C.

Aquat Toxicol. 2004 Mar 10;66(4):419-25.

PMID:
15168949
41.

Flow cytometry as a tool to quantify oyster defence mechanisms.

Goedken M, De Guise S.

Fish Shellfish Immunol. 2004 Apr;16(4):539-52.

PMID:
15123295
42.

Characterization of F21.A, a monoclonal antibody that recognize a leucocyte surface antigen for killer whale homologue to beta-2 integrin.

De Guise S, Erickson K, Blanchard M, DiMolfetto L, Lepper HD, Stott JL, Ferrick DA.

Vet Immunol Immunopathol. 2004 Feb;97(3-4):195-206.

PMID:
14741138
43.
44.
45.

Evidence of Brucella sp. infection in marine mammals stranded along the coast of southern New England.

Maratea J, Ewalt DR, Frasca S Jr, Dunn JL, De Guise S, Szkudlarek L, St Aubin DJ, French RA.

J Zoo Wildl Med. 2003 Sep;34(3):256-61.

PMID:
14582787
46.

Monoclonal antibodies to lymphocyte surface antigens for cetacean homologues to CD2, CD19 and CD21.

De Guise S, Erickson K, Blanchard M, DiMolfetto L, Lepper HD, Wang J, Stott JL, Ferrick DA.

Vet Immunol Immunopathol. 2002 Jan 15;84(3-4):209-21.

PMID:
11777535
47.

Consensus statement: Atlantic Coast Contaminants Workshop 2000.

De Guise S, Shaw SD, Barclay JS, Brock J, Brouwer A, Dewailly E, Fair PA, Fournier M, Grandjean P, Guillette LJ Jr, Hahn ME, Koopman-Esseboom C, Letcher RJ, Matz A, Norstrom RJ, Perkins CR, Schwacke L, Skaare JU, Sowles J, St Aubin DJ, Stegeman J, Whaley JE.

Environ Health Perspect. 2001 Dec;109(12):1301-2. No abstract available.

48.

Mycobacterium marinum dermatitis and panniculitis with chronic pleuritis in a captive white whale (Delphinapterus leucas) with aortic rupture.

Bowenkamp KE, Frasca S Jr, Draghi A 2nd, Tsongalis GJ, Koerting C, Hinckley L, De Guise S, Montali RJ, Goertz CE, St Aubin DJ, Dunn JL.

J Vet Diagn Invest. 2001 Nov;13(6):524-30.

PMID:
11724146
49.
50.

Purification of functional T lymphocytes from splenocytes of the beluga whales (Delphinapterus leucas).

Bernier J, De Guise S, Martineau D, Béland P, Beaudet M, Fournier M.

Dev Comp Immunol. 2000 Sep-Oct;24(6-7):653-62.

PMID:
10831799

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