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Items: 1 to 50 of 319

1.

Modulation of genomic and epigenetic end-points by celecoxib.

Izzotti A, La Maestra S, Micale RT, Pulliero A, Geretto M, Balansky R, De Flora S.

Oncotarget. 2018 Sep 14;9(72):33656-33681. doi: 10.18632/oncotarget.26062. eCollection 2018 Sep 14.

2.

Aspirin Abrogates Impairment of Mammary Gland Differentiation induced by Early in Life Second-hand Smoke in Mice.

Santucci-Pereira J, Pogash TJ, Patel A, Hundal N, Barton M, Camoirano A, Micale RT, La Maestra S, Balansky R, De Flora S, Russo J.

Carcinogenesis. 2018 May 17. doi: 10.1093/carcin/bgy064. [Epub ahead of print]

3.

Release of MicroRNAs into Body Fluids from Ten Organs of Mice Exposed to Cigarette Smoke.

Izzotti A, Longobardi M, La Maestra S, Micale RT, Pulliero A, Camoirano A, Geretto M, D'Agostini F, Balansky R, Miller MS, Steele VE, De Flora S.

Theranostics. 2018 Mar 8;8(8):2147-2160. doi: 10.7150/thno.22726. eCollection 2018.

4.

Carcinogenic response and other histopathological alterations in mice exposed to cigarette smoke for varying time periods after birth.

Balansky R, Ganchev G, Iltcheva M, Dimitrova E, Micale RT, La Maestra S, De Flora S.

Carcinogenesis. 2018 Apr 5;39(4):580-587. doi: 10.1093/carcin/bgy013.

PMID:
29370344
5.

Early and late effects of aspirin and naproxen on microRNAs in the lung and blood of mice, either unexposed or exposed to cigarette smoke.

Izzotti A, Balansky R, Ganchev G, Iltcheva M, Longobardi M, Pulliero A, Camoirano A, D'Agostini F, Geretto M, Micale RT, La Maestra S, Miller MS, Steele VE, De Flora S.

Oncotarget. 2017 Aug 24;8(49):85716-85748. doi: 10.18632/oncotarget.20464. eCollection 2017 Oct 17.

6.

Modulation by Ethanol of Cigarette Smoke Clastogenicity in Cells of Adult Mice and of Transplacentally Exposed Fetuses.

Balansky R, La Maestra S, Micale RT, Iltcheva M, Kirov K, De Flora S.

PLoS One. 2016 Dec 1;11(12):e0167239. doi: 10.1371/journal.pone.0167239. eCollection 2016.

7.

Interactions between ethanol and cigarette smoke in a mouse lung carcinogenesis model.

Balansky R, Ganchev G, Iltcheva M, Nikolov M, La Maestra S, Micale RT, Steele VE, De Flora S.

Toxicology. 2016 Dec 12;373:54-62. doi: 10.1016/j.tox.2016.11.008. Epub 2016 Nov 10.

PMID:
27840117
8.

Blood and lung microRNAs as biomarkers of pulmonary tumorigenesis in cigarette smoke-exposed mice.

Izzotti A, Balansky R, Ganchev G, Iltcheva M, Longobardi M, Pulliero A, Geretto M, Micale RT, La Maestra S, Miller MS, Steele VE, De Flora S.

Oncotarget. 2016 Dec 20;7(51):84758-84774. doi: 10.18632/oncotarget.12475.

9.

Reduction of hexavalent chromium by fasted and fed human gastric fluid. I. Chemical reduction and mitigation of mutagenicity.

De Flora S, Camoirano A, Micale RT, La Maestra S, Savarino V, Zentilin P, Marabotto E, Suh M, Proctor DM.

Toxicol Appl Pharmacol. 2016 Sep 1;306:113-9. doi: 10.1016/j.taap.2016.07.004. Epub 2016 Jul 9.

10.

Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling.

Kirman CR, Suh M, Hays SM, Gürleyük H, Gerads R, De Flora S, Parker W, Lin S, Haws LC, Harris MA, Proctor DM.

Toxicol Appl Pharmacol. 2016 Sep 1;306:120-33. doi: 10.1016/j.taap.2016.07.002. Epub 2016 Jul 7.

11.

Epidemiology of cancers of infectious origin and prevention strategies.

De Flora S, La Maestra S.

J Prev Med Hyg. 2015 Jun 10;56(1):E15-20. Review.

12.

Pharmacological Modulation of Lung Carcinogenesis in Smokers: Preclinical and Clinical Evidence.

De Flora S, Ganchev G, Iltcheva M, La Maestra S, Micale RT, Steele VE, Balansky R.

Trends Pharmacol Sci. 2016 Feb;37(2):120-142. doi: 10.1016/j.tips.2015.11.003. Epub 2015 Dec 23. Review.

13.

Addressing the Core of Carcinogenesis: How a Mitochondrial Mutation Leads to Metabolic Remodeling in Familial Cancers.

De Flora A, De Flora S.

J Natl Cancer Inst. 2016 Jan;108(1). doi: 10.1093/jnci/djv321. No abstract available.

PMID:
26719883
14.

Exposing native cyprinid (Barbus plebejus) juveniles to river sediments leads to gonadal alterations, genotoxic effects and thyroid disruption.

Viganò L, De Flora S, Gobbi M, Guiso G, Izzotti A, Mandich A, Mascolo G, Roscioli C.

Aquat Toxicol. 2015 Dec;169:223-39. doi: 10.1016/j.aquatox.2015.10.022. Epub 2015 Nov 2.

PMID:
26580918
15.

Incidence of infection-associated cancers in Italy and prevention strategies.

De Flora S, Crocetti E, Bonanni P, Ferro A, Vitale F; Vaccines and Cancer Prevention/Screening Working Groups of the Italian Society of Hygiene, Preventive Medicine and Public Health (SItI).

Epidemiol Prev. 2015 Jul-Aug;39(4 Suppl 1):14-20. Review.

16.

Modulation by aspirin and naproxen of nucleotide alterations and tumors in the lung of mice exposed to environmental cigarette smoke since birth.

La Maestra S, D'Agostini F, Izzotti A, Micale RT, Mastracci L, Camoirano A, Balansky R, Trosko JE, Steele VE, De Flora S.

Carcinogenesis. 2015 Dec;36(12):1531-8. doi: 10.1093/carcin/bgv149. Epub 2015 Oct 13.

17.

Environmental impact of multi-wall carbon nanotubes in a novel model of exposure: systemic distribution, macrophage accumulation, and amyloid deposition.

Albini A, Pagani A, Pulze L, Bruno A, Principi E, Congiu T, Gini E, Grimaldi A, Bassani B, De Flora S, de Eguileor M, Noonan DM.

Int J Nanomedicine. 2015 Sep 29;10:6133-45. doi: 10.2147/IJN.S85275. eCollection 2015.

18.

Selective inhibition by aspirin and naproxen of mainstream cigarette smoke-induced genotoxicity and lung tumors in female mice.

Balansky R, Ganchev G, Iltcheva M, Micale RT, La Maestra S, D'Oria C, Steele VE, De Flora S.

Arch Toxicol. 2016 May;90(5):1251-60. doi: 10.1007/s00204-015-1550-5. Epub 2015 Jun 24.

PMID:
26104855
19.

Modulation by licofelone and celecoxib of experimentally induced cancer and preneoplastic lesions in mice exposed to cigarette smoke.

Balansky R, Ganchev G, Iltcheva M, Nikolov M, La Maestra S, Micale RT, D'Agostini F, Steele VE, De Flora S.

Curr Cancer Drug Targets. 2015;15(3):188-95.

PMID:
25687474
20.

Age-related mortality trends in Italy from 1901 to 2008.

Vercelli M, Lillini R, Quaglia A, Micale RT, La Maestra S, De Flora S.

PLoS One. 2014 Dec 8;9(12):e114027. doi: 10.1371/journal.pone.0114027. eCollection 2014.

21.

Effect of cigarette smoke on DNA damage, oxidative stress, and morphological alterations in mouse testis and spermatozoa.

La Maestra S, De Flora S, Micale RT.

Int J Hyg Environ Health. 2015 Jan;218(1):117-22. doi: 10.1016/j.ijheh.2014.08.006. Epub 2014 Sep 11.

PMID:
25260855
22.

Assay of lapatinib in murine models of cigarette smoke carcinogenesis.

Balansky R, Izzotti A, D'Agostini F, Longobardi M, Micale RT, La Maestra S, Camoirano A, Ganchev G, Iltcheva M, Steele VE, De Flora S.

Carcinogenesis. 2014 Oct;35(10):2300-7. doi: 10.1093/carcin/bgu154. Epub 2014 Jul 22.

23.

Rationale and approaches to the prevention of smoking-related diseases: overview of recent studies on chemoprevention of smoking-induced tumors in rodent models.

De Flora S, Izzotti A, D'Agostini F, La Maestra S, Micale RT, Ceccaroli C, Steele VE, Balansky R.

J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2014;32(2):105-20. doi: 10.1080/10590501.2014.907459. Review.

PMID:
24875440
24.

Does second-hand smoke affect semen quality?

La Maestra S, De Flora S, Micale RT.

Arch Toxicol. 2014 Jun;88(6):1187-8. doi: 10.1007/s00204-014-1241-7. Epub 2014 May 18. No abstract available.

PMID:
24838294
25.

Modulation by metformin of molecular and histopathological alterations in the lung of cigarette smoke-exposed mice.

Izzotti A, Balansky R, D'Agostini F, Longobardi M, Cartiglia C, Micale RT, La Maestra S, Camoirano A, Ganchev G, Iltcheva M, Steele VE, De Flora S.

Cancer Med. 2014 Jun;3(3):719-30. doi: 10.1002/cam4.234. Epub 2014 Mar 28.

26.

Genotoxic damage in the oral mucosal cells of subjects carrying restorative dental fillings.

Visalli G, Baluce B, La Maestra S, Micale RT, Cingano L, De Flora S, Di Pietro A.

Arch Toxicol. 2013 Dec;87(12):2247-8. doi: 10.1007/s00204-013-1155-9. Epub 2013 Nov 16. No abstract available.

PMID:
24241249
27.

Transplacental clastogenic and epigenetic effects of gold nanoparticles in mice.

Balansky R, Longobardi M, Ganchev G, Iltcheva M, Nedyalkov N, Atanasov P, Toshkova R, De Flora S, Izzotti A.

Mutat Res. 2013 Nov-Dec;751-752:42-8. doi: 10.1016/j.mrfmmm.2013.08.006. Epub 2013 Sep 1.

PMID:
24004569
28.

Relationships between pulmonary micro-RNA and proteome profiles, systemic cytogenetic damage and lung tumors in cigarette smoke-exposed mice treated with chemopreventive agents.

Izzotti A, Balansky R, D'Agostini F, Longobardi M, Cartiglia C, La Maestra S, Micale RT, Camoirano A, Ganchev G, Iltcheva M, Steele VE, De Flora S.

Carcinogenesis. 2013 Oct;34(10):2322-9. doi: 10.1093/carcin/bgt178. Epub 2013 May 24.

29.

Yearly variations of demographic indices and mortality data in Italy from 1901 to 2008 as related to the caloric intake.

Vercelli M, Lillini R, Quaglia A, La Maestra S, Micale RT, Caldora M, De Flora S.

Int J Hyg Environ Health. 2013 Nov;216(6):763-71. doi: 10.1016/j.ijheh.2013.02.003. Epub 2013 Mar 7.

PMID:
23523154
30.

Oxidative stress in the lung of mice exposed to cigarette smoke either early in life or in adulthood.

Micale RT, La Maestra S, Di Pietro A, Visalli G, Baluce B, Balansky R, Steele VE, De Flora S.

Arch Toxicol. 2013 May;87(5):915-8. doi: 10.1007/s00204-012-0993-1. Epub 2013 Feb 20. Erratum in: Arch Toxicol. 2013 May;87(5):919. Maestra, Sebastiano La [corrected to La Maestra, Sebastiano]; Pietro, Angela Di [corrected to Di Pietro, Angela].

PMID:
23423711
31.

Genotoxicity and carcinogenicity of the light emitted by artificial illumination systems.

De Flora S.

Arch Toxicol. 2013 Mar;87(3):403-5. doi: 10.1007/s00204-013-1015-7. Epub 2013 Feb 1.

PMID:
23371415
32.

Genomic and post-genomic effects of cigarette smoke: mechanisms and implications for risk assessment and prevention strategies.

De Flora S, Bartsch H.

Int J Cancer. 2012 Dec 15;131(12):2721-3. doi: 10.1002/ijc.27833. No abstract available.

33.

DNA damage in exfoliated cells and histopathological alterations in the urinary tract of mice exposed to cigarette smoke and treated with chemopreventive agents.

La Maestra S, Micale RT, De Flora S, D'Agostini F, Ganchev G, Iltcheva M, Petkov N, Steele VE, Balansky R.

Carcinogenesis. 2013 Jan;34(1):183-9. doi: 10.1093/carcin/bgs314. Epub 2012 Oct 5.

34.

Smoke-induced microRNA and related proteome alterations. Modulation by chemopreventive agents.

De Flora S, Balansky R, D'Agostini F, Cartiglia C, Longobardi M, Steele VE, Izzotti A.

Int J Cancer. 2012 Dec 15;131(12):2763-73. doi: 10.1002/ijc.27814. Epub 2012 Sep 26. Review.

35.

Genotoxic damage in the oral mucosa cells of subjects carrying restorative dental fillings.

Visalli G, Baluce B, La Maestra S, Micale RT, Cingano L, De Flora S, Di Pietro A.

Arch Toxicol. 2013 Jan;87(1):179-87. doi: 10.1007/s00204-012-0915-2. Epub 2012 Aug 8.

PMID:
22872142
36.

Chemoprevention of doxorubicin-induced alopecia in mice by dietary administration of L-cystine and vitamin B6.

D'Agostini F, Fiallo P, Ghio M, De Flora S.

Arch Dermatol Res. 2013 Jan;305(1):25-34. doi: 10.1007/s00403-012-1253-1. Epub 2012 Jun 15.

PMID:
22699427
37.

MicroRNAs as targets for dietary and pharmacological inhibitors of mutagenesis and carcinogenesis.

Izzotti A, Cartiglia C, Steele VE, De Flora S.

Mutat Res. 2012 Oct-Dec;751(2):287-303. doi: 10.1016/j.mrrev.2012.05.004. Epub 2012 Jun 7. Review.

38.

Cytogenetic analysis of gingival epithelial cells, as related to smoking habits and occurrence of periodontal disease.

D'Agostini F, Calcagno E, Micale RT, La Maestra S, De Flora S, Cingano L.

Int J Hyg Environ Health. 2013 Jan;216(1):71-5. doi: 10.1016/j.ijheh.2012.01.005. Epub 2012 Feb 20.

PMID:
22357102
39.

Inhibition of lung tumor development by berry extracts in mice exposed to cigarette smoke.

Balansky R, Ganchev G, Iltcheva M, Kratchanova M, Denev P, Kratchanov C, Polasa K, D'Agostini F, Steele VE, De Flora S.

Int J Cancer. 2012 Nov 1;131(9):1991-7. doi: 10.1002/ijc.27486. Epub 2012 Mar 27.

40.

Transplacental antioxidants inhibit lung tumors in mice exposed to cigarette smoke after birth: a novel preventative strategy?

Balansky R, Ganchev G, Iltcheva M, Steele VE, De Flora S.

Curr Cancer Drug Targets. 2012 Feb;12(2):164-9.

PMID:
22165969
41.

[Mechanistic issues and prevention strategies targeting occupational carcinogenesis].

De Flora S, La Maestra S, Micale RT.

G Ital Med Lav Ergon. 2011 Jul-Sep;33(3):294-9. Italian.

PMID:
22073678
42.

Dose-related cytogenetic damage in pulmonary alveolar macrophages from mice exposed to cigarette smoke early in life.

Balansky R, D'Agostini F, Micale RT, La Maestra S, Steele VE, De Flora S.

Arch Toxicol. 2012 Mar;86(3):509-16. doi: 10.1007/s00204-011-0765-3. Epub 2011 Oct 12.

PMID:
21989788
43.

Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice.

La Maestra S, Kisby GE, Micale RT, Johnson J, Kow YW, Bao G, Sheppard C, Stanfield S, Tran H, Woltjer RL, D'Agostini F, Steele VE, De Flora S.

Toxicol Sci. 2011 Oct;123(2):471-9. doi: 10.1093/toxsci/kfr187. Epub 2011 Jul 21.

44.

Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: is DIM a substitute for I3C?

Lubet RA, Heckman BM, De Flora SL, Steele VE, Crowell JA, Juliana MM, Grubbs CJ.

Oncol Rep. 2011 Sep;26(3):731-6. doi: 10.3892/or.2011.1316. Epub 2011 May 23.

PMID:
21617870
45.

Upregulation of clusterin in prostate and DNA damage in spermatozoa from bisphenol A-treated rats and formation of DNA adducts in cultured human prostatic cells.

De Flora S, Micale RT, La Maestra S, Izzotti A, D'Agostini F, Camoirano A, Davoli SA, Troglio MG, Rizzi F, Davalli P, Bettuzzi S.

Toxicol Sci. 2011 Jul;122(1):45-51. doi: 10.1093/toxsci/kfr096. Epub 2011 May 2.

PMID:
21536718
46.

Differential carcinogenicity of cigarette smoke in mice exposed either transplacentally, early in life or in adulthood.

Balansky R, Ganchev G, Iltcheva M, Nikolov M, Steele VE, De Flora S.

Int J Cancer. 2012 Mar 1;130(5):1001-10. doi: 10.1002/ijc.26103. Epub 2011 May 30.

47.

The prevention of infection-associated cancers.

De Flora S, Bonanni P.

Carcinogenesis. 2011 Jun;32(6):787-95. doi: 10.1093/carcin/bgr054. Epub 2011 Mar 24. Review.

48.

Dose-responsiveness and persistence of microRNA expression alterations induced by cigarette smoke in mouse lung.

Izzotti A, Larghero P, Longobardi M, Cartiglia C, Camoirano A, Steele VE, De Flora S.

Mutat Res. 2011 Dec 1;717(1-2):9-16. doi: 10.1016/j.mrfmmm.2010.12.008. Epub 2010 Dec 24.

PMID:
21185844
49.

Diet-derived phytochemicals: from cancer chemoprevention to cardio-oncological prevention.

Ferrari N, Tosetti F, De Flora S, Donatelli F, Sogno I, Noonan DM, Albini A.

Curr Drug Targets. 2011 Dec;12(13):1909-24. Review.

PMID:
21158708
50.

Multigenerational mitochondrial alterations in pneumocytes exposed to oil fly ash metals.

Di Pietro A, Visalli G, Baluce B, Micale RT, La Maestra S, Spataro P, De Flora S.

Int J Hyg Environ Health. 2011 Mar;214(2):138-44. doi: 10.1016/j.ijheh.2010.10.003. Epub 2010 Nov 20.

PMID:
21095158

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