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Items: 28


Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo.

De Feyter HM, Behar KL, Corbin ZA, Fulbright RK, Brown PB, McIntyre S, Nixon TW, Rothman DL, de Graaf RA.

Sci Adv. 2018 Aug 22;4(8):eaat7314. doi: 10.1126/sciadv.aat7314. eCollection 2018 Aug.


Elliptical localization with pulsed second-order fields (ECLIPSE) for robust lipid suppression in proton MRSI.

de Graaf RA, Brown PB, De Feyter HM, McIntyre S, Nixon TW.

NMR Biomed. 2018 Sep;31(9):e3949. doi: 10.1002/nbm.3949. Epub 2018 Jul 9.


The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects.

Abdallah CG, De Feyter HM, Averill LA, Jiang L, Averill CL, Chowdhury GMI, Purohit P, de Graaf RA, Esterlis I, Juchem C, Pittman BP, Krystal JH, Rothman DL, Sanacora G, Mason GF.

Neuropsychopharmacology. 2018 Sep;43(10):2154-2160. doi: 10.1038/s41386-018-0136-3. Epub 2018 Jun 28.


Selective proton-observed, carbon-edited (selPOCE) MRS method for measurement of glutamate and glutamine 13 C-labeling in the human frontal cortex.

De Feyter HM, Herzog RI, Steensma BR, Klomp DWJ, Brown PB, Mason GF, Rothman DL, de Graaf RA.

Magn Reson Med. 2018 Jul;80(1):11-20. doi: 10.1002/mrm.27003. Epub 2017 Nov 13.


Comparison of direct 13C and indirect 1H-[13C] MR detection methods for the study of dynamic metabolic turnover in the human brain.

Chen H, De Feyter HM, Brown PB, Rothman DL, Cai S, de Graaf RA.

J Magn Reson. 2017 Oct;283:33-44. doi: 10.1016/j.jmr.2017.08.004. Epub 2017 Aug 12.


"What to eat or what not to eat-that is still the question" - Reply.

De Feyter HM, Behar KL, de Graaf RA, Rothman DL.

Neuro Oncol. 2017 Apr 1;19(4):596-597. doi: 10.1093/neuonc/now291. No abstract available.


2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.

Sulkowski PL, Corso CD, Robinson ND, Scanlon SE, Purshouse KR, Bai H, Liu Y, Sundaram RK, Hegan DC, Fons NR, Breuer GA, Song Y, Mishra-Gorur K, De Feyter HM, de Graaf RA, Surovtseva YV, Kachman M, Halene S, G√ľnel M, Glazer PM, Bindra RS.

Sci Transl Med. 2017 Feb 1;9(375). pii: eaal2463. doi: 10.1126/scitranslmed.aal2463.


Detection of cerebral NAD+ in humans at 7T.

de Graaf RA, De Feyter HM, Brown PB, Nixon TW, Rothman DL, Behar KL.

Magn Reson Med. 2017 Sep;78(3):828-835. doi: 10.1002/mrm.26465. Epub 2016 Sep 26.


A ketogenic diet increases transport and oxidation of ketone bodies in RG2 and 9L gliomas without affecting tumor growth.

De Feyter HM, Behar KL, Rao JU, Madden-Hennessey K, Ip KL, Hyder F, Drewes LR, Geschwind JF, de Graaf RA, Rothman DL.

Neuro Oncol. 2016 Aug;18(8):1079-87. doi: 10.1093/neuonc/now088. Epub 2016 May 3.


Imaging the intratumoral-peritumoral extracellular pH gradient of gliomas.

Coman D, Huang Y, Rao JU, De Feyter HM, Rothman DL, Juchem C, Hyder F.

NMR Biomed. 2016 Mar;29(3):309-19. doi: 10.1002/nbm.3466. Epub 2016 Jan 11.


High-sensitivity, broadband-decoupled (13) C MR spectroscopy in humans at 7T using two-dimensional heteronuclear single-quantum coherence.

de Graaf RA, De Feyter HM, Rothman DL.

Magn Reson Med. 2015 Oct;74(4):903-14. doi: 10.1002/mrm.25470. Epub 2014 Sep 29.


Characterization of cerebral glutamine uptake from blood in the mouse brain: implications for metabolic modeling of 13C NMR data.

Bagga P, Behar KL, Mason GF, De Feyter HM, Rothman DL, Patel AB.

J Cereb Blood Flow Metab. 2014 Oct;34(10):1666-72. doi: 10.1038/jcbfm.2014.129. Epub 2014 Jul 30.


Glutamate metabolism in major depressive disorder.

Abdallah CG, Jiang L, De Feyter HM, Fasula M, Krystal JH, Rothman DL, Mason GF, Sanacora G.

Am J Psychiatry. 2014 Dec 1;171(12):1320-7. doi: 10.1176/appi.ajp.2014.14010067. Epub 2014 Oct 31.


Increased brain transport and metabolism of acetate in hypoglycemia unawareness.

Gulanski BI, De Feyter HM, Page KA, Belfort-DeAguiar R, Mason GF, Rothman DL, Sherwin RS.

J Clin Endocrinol Metab. 2013 Sep;98(9):3811-20. doi: 10.1210/jc.2013-1701. Epub 2013 Jun 24.


Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals.

De Feyter HM, Mason GF, Shulman GI, Rothman DL, Petersen KF.

Diabetes. 2013 Sep;62(9):3075-80. doi: 10.2337/db13-0313. Epub 2013 May 28.


Increased brain uptake and oxidation of acetate in heavy drinkers.

Jiang L, Gulanski BI, De Feyter HM, Weinzimer SA, Pittman B, Guidone E, Koretski J, Harman S, Petrakis IL, Krystal JH, Mason GF.

J Clin Invest. 2013 Apr;123(4):1605-14. doi: 10.1172/JCI65153. Epub 2013 Mar 8.


Is there in vivo evidence for amino acid shuttles carrying ammonia from neurons to astrocytes?

Rothman DL, De Feyter HM, Maciejewski PK, Behar KL.

Neurochem Res. 2012 Nov;37(11):2597-612. doi: 10.1007/s11064-012-0898-7. Epub 2012 Oct 27. Review.


Physical activity is the key determinant of skeletal muscle mitochondrial function in type 2 diabetes.

van Tienen FH, Praet SF, de Feyter HM, van den Broek NM, Lindsey PJ, Schoonderwoerd KG, de Coo IF, Nicolay K, Prompers JJ, Smeets HJ, van Loon LJ.

J Clin Endocrinol Metab. 2012 Sep;97(9):3261-9. doi: 10.1210/jc.2011-3454. Epub 2012 Jul 16.


Myofibrillar distribution of succinate dehydrogenase activity and lipid stores differs in skeletal muscle tissue of paraplegic subjects.

Jonkers RA, Dirks ML, Nabuurs CI, De Feyter HM, Praet SF, Nicolay K, van Loon LJ, Prompers JJ.

Am J Physiol Endocrinol Metab. 2012 Feb 1;302(3):E365-73. doi: 10.1152/ajpendo.00270.2011. Epub 2011 Nov 8.


13C MRS studies of neuroenergetics and neurotransmitter cycling in humans.

Rothman DL, De Feyter HM, de Graaf RA, Mason GF, Behar KL.

NMR Biomed. 2011 Oct;24(8):943-57. doi: 10.1002/nbm.1772. Epub 2011 Aug 31. Review.


Increased mitochondrial content rescues in vivo muscle oxidative capacity in long-term high-fat-diet-fed rats.

van den Broek NM, Ciapaite J, De Feyter HM, Houten SM, Wanders RJ, Jeneson JA, Nicolay K, Prompers JJ.

FASEB J. 2010 May;24(5):1354-64. doi: 10.1096/fj.09-143842. Epub 2009 Dec 29.


Adaptations in mitochondrial function parallel, but fail to rescue, the transition to severe hyperglycemia and hyperinsulinemia: a study in Zucker diabetic fatty rats.

Lenaers E, De Feyter HM, Hoeks J, Schrauwen P, Schaart G, Nabben M, Nicolay K, Prompers JJ, Hesselink MK.

Obesity (Silver Spring). 2010 Jun;18(6):1100-7. doi: 10.1038/oby.2009.372. Epub 2009 Oct 29.


Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of type 2 diabetes.

De Feyter HM, Lenaers E, Houten SM, Schrauwen P, Hesselink MK, Wanders RJ, Nicolay K, Prompers JJ.

FASEB J. 2008 Nov;22(11):3947-55. doi: 10.1096/fj.08-112318. Epub 2008 Jul 24.


Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle mitochondrial dysfunction.

De Feyter HM, van den Broek NM, Praet SF, Nicolay K, van Loon LJ, Prompers JJ.

Eur J Endocrinol. 2008 May;158(5):643-53. doi: 10.1530/EJE-07-0756.


Exercise training improves glycemic control in long-standing insulin-treated type 2 diabetic patients.

De Feyter HM, Praet SF, van den Broek NM, Kuipers H, Stehouwer CD, Nicolay K, Prompers JJ, van Loon LJ.

Diabetes Care. 2007 Oct;30(10):2511-3. Epub 2007 Jul 12. No abstract available.


Intersubject differences in the effect of acidosis on phosphocreatine recovery kinetics in muscle after exercise are due to differences in proton efflux rates.

van den Broek NM, De Feyter HM, de Graaf L, Nicolay K, Prompers JJ.

Am J Physiol Cell Physiol. 2007 Jul;293(1):C228-37. Epub 2007 Mar 28.


31P MR spectroscopy and in vitro markers of oxidative capacity in type 2 diabetes patients.

Praet SF, De Feyter HM, Jonkers RA, Nicolay K, van Pul C, Kuipers H, van Loon LJ, Prompers JJ.

MAGMA. 2006 Dec;19(6):321-31. Epub 2006 Dec 19.


Regional variations in intramyocellular lipid concentration correlate with muscle fiber type distribution in rat tibialis anterior muscle.

De Feyter HM, Schaart G, Hesselink MK, Schrauwen P, Nicolay K, Prompers JJ.

Magn Reson Med. 2006 Jul;56(1):19-25.

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