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Items: 1 to 50 of 57

1.

A bio-guided approach for the development of a chestnut-based proanthocyanidin-enriched nutraceutical with potential anti-gastritis properties.

Sangiovanni E, Piazza S, Vrhovsek U, Fumagalli M, Khalilpour S, Masuero D, Di Lorenzo C, Colombo L, Mattivi F, De Fabiani E, Dell'Agli M.

Pharmacol Res. 2018 Aug;134:145-155. doi: 10.1016/j.phrs.2018.06.016. Epub 2018 Jun 18.

PMID:
29928974
2.

Zc3h10 is a novel mitochondrial regulator.

Audano M, Pedretti S, Cermenati G, Brioschi E, Diaferia GR, Ghisletti S, Cuomo A, Bonaldi T, Salerno F, Mora M, Grigore L, Garlaschelli K, Baragetti A, Bonacina F, Catapano AL, Norata GD, Crestani M, Caruso D, Saez E, De Fabiani E, Mitro N.

EMBO Rep. 2018 Apr;19(4). pii: e45531. doi: 10.15252/embr.201745531. Epub 2018 Mar 5.

PMID:
29507079
3.

Gender-related metabolomics and lipidomics: From experimental animal models to clinical evidence.

Audano M, Maldini M, De Fabiani E, Mitro N, Caruso D.

J Proteomics. 2018 Apr 30;178:82-91. doi: 10.1016/j.jprot.2017.11.001. Epub 2017 Nov 6. Review.

PMID:
29122727
4.

Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases.

Ferrari A, Fiorino E, Longo R, Barilla S, Mitro N, Cermenati G, Giudici M, Caruso D, Mai A, Guerrini U, De Fabiani E, Crestani M.

Int J Obes (Lond). 2017 Feb;41(2):289-298. doi: 10.1038/ijo.2016.191. Epub 2016 Oct 28.

PMID:
27795551
5.

Strawberry tannins inhibit IL-8 secretion in a cell model of gastric inflammation.

Fumagalli M, Sangiovanni E, Vrhovsek U, Piazza S, Colombo E, Gasperotti M, Mattivi F, De Fabiani E, Dell'Agli M.

Pharmacol Res. 2016 Sep;111:703-712. doi: 10.1016/j.phrs.2016.07.028. Epub 2016 Jul 27.

PMID:
27473819
6.

Lack of sterol regulatory element binding factor-1c imposes glial Fatty Acid utilization leading to peripheral neuropathy.

Cermenati G, Audano M, Giatti S, Carozzi V, Porretta-Serapiglia C, Pettinato E, Ferri C, D'Antonio M, De Fabiani E, Crestani M, Scurati S, Saez E, Azcoitia I, Cavaletti G, Garcia-Segura LM, Melcangi RC, Caruso D, Mitro N.

Cell Metab. 2015 Apr 7;21(4):571-83. doi: 10.1016/j.cmet.2015.02.016. Epub 2015 Mar 26.

7.

Olive oil phenolic extract regulates interleukin-8 expression by transcriptional and posttranscriptional mechanisms in Caco-2 cells.

Muto E, Dell'Agli M, Sangiovanni E, Mitro N, Fumagalli M, Crestani M, De Fabiani E, Caruso D.

Mol Nutr Food Res. 2015 Jun;59(6):1217-21. doi: 10.1002/mnfr.201400800. Epub 2015 Apr 27.

PMID:
25708117
8.

Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function.

Audano M, Ferrari A, Fiorino E, Kuenzl M, Caruso D, Mitro N, Crestani M, De Fabiani E.

Curr Genomics. 2014 Dec;15(6):436-56. doi: 10.2174/138920291506150106151119.

9.

Lipids in the nervous system: from biochemistry and molecular biology to patho-physiology.

Cermenati G, Mitro N, Audano M, Melcangi RC, Crestani M, De Fabiani E, Caruso D.

Biochim Biophys Acta. 2015 Jan;1851(1):51-60. doi: 10.1016/j.bbalip.2014.08.011. Epub 2014 Aug 20. Review.

PMID:
25150974
10.

Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy.

Mitro N, Cermenati G, Brioschi E, Abbiati F, Audano M, Giatti S, Crestani M, De Fabiani E, Azcoitia I, Garcia-Segura LM, Caruso D, Melcangi RC.

J Steroid Biochem Mol Biol. 2014 Sep;143:115-21. doi: 10.1016/j.jsbmb.2014.02.015. Epub 2014 Mar 4.

PMID:
24607810
11.

The sirtuin class of histone deacetylases: regulation and roles in lipid metabolism.

Fiorino E, Giudici M, Ferrari A, Mitro N, Caruso D, De Fabiani E, Crestani M.

IUBMB Life. 2014 Feb;66(2):89-99. doi: 10.1002/iub.1246. Epub 2014 Feb 3. Review.

12.

LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.

Gilardi F, Giudici M, Mitro N, Maschi O, Guerrini U, Rando G, Maggi A, Cermenati G, Laghezza A, Loiodice F, Pochetti G, Lavecchia A, Caruso D, De Fabiani E, Bamberg K, Crestani M.

J Biol Chem. 2014 Mar 7;289(10):6908-20. doi: 10.1074/jbc.M113.506394. Epub 2014 Jan 22.

13.

Linking epigenetics to lipid metabolism: focus on histone deacetylases.

Ferrari A, Fiorino E, Giudici M, Gilardi F, Galmozzi A, Mitro N, Cermenati G, Godio C, Caruso D, De Fabiani E, Crestani M.

Mol Membr Biol. 2012 Nov;29(7):257-66. doi: 10.3109/09687688.2012.729094. Epub 2012 Oct 24. Review.

PMID:
23095054
14.

Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue.

Galmozzi A, Mitro N, Ferrari A, Gers E, Gilardi F, Godio C, Cermenati G, Gualerzi A, Donetti E, Rotili D, Valente S, Guerrini U, Caruso D, Mai A, Saez E, De Fabiani E, Crestani M.

Diabetes. 2013 Mar;62(3):732-42. doi: 10.2337/db12-0548. Epub 2012 Oct 15.

15.

Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation.

Cermenati G, Abbiati F, Cermenati S, Brioschi E, Volonterio A, Cavaletti G, Saez E, De Fabiani E, Crestani M, Garcia-Segura LM, Melcangi RC, Caruso D, Mitro N.

J Lipid Res. 2012 Feb;53(2):300-10. doi: 10.1194/jlr.M021188. Epub 2011 Dec 7.

16.

Enterodiol and enterolactone modulate the immune response by acting on nuclear factor-kappaB (NF-kappaB) signaling.

Corsini E, Dell'Agli M, Facchi A, De Fabiani E, Lucchi L, Boraso MS, Marinovich M, Galli CL.

J Agric Food Chem. 2010 Jun 9;58(11):6678-84. doi: 10.1021/jf100471n.

PMID:
20446732
17.

When food meets man: the contribution of epigenetics to health.

De Fabiani E, Mitro N, Gilardi F, Galmozzi A, Caruso D, Crestani M.

Nutrients. 2010 May;2(5):551-71. doi: 10.3390/nu2050551. Epub 2010 May 25. Review.

18.

Sterol-protein interactions in cholesterol and bile acid synthesis.

De Fabiani E, Mitro N, Gilardi F, Crestani M.

Subcell Biochem. 2010;51:109-35. doi: 10.1007/978-90-481-8622-8_4. Review.

PMID:
20213542
19.

Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kappaB signaling.

Dell'Agli M, Fagnani R, Galli GV, Maschi O, Gilardi F, Bellosta S, Crestani M, Bosisio E, De Fabiani E, Caruso D.

J Agric Food Chem. 2010 Feb 24;58(4):2246-52. doi: 10.1021/jf9042503.

PMID:
20102205
20.

Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling.

Gilardi F, Viviani B, Galmozzi A, Boraso M, Bartesaghi S, Torri A, Caruso D, Crestani M, Marinovich M, de Fabiani E.

Neuroscience. 2009 Dec 1;164(2):530-40. doi: 10.1016/j.neuroscience.2009.08.003. Epub 2009 Aug 7.

PMID:
19665519
21.

Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors.

Mai A, Valente S, Meade S, Carafa V, Tardugno M, Nebbioso A, Galmozzi A, Mitro N, De Fabiani E, Altucci L, Kazantsev A.

J Med Chem. 2009 Sep 10;52(17):5496-504. doi: 10.1021/jm9008289.

PMID:
19663498
22.

Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis.

Bennati AM, Schiavoni G, Franken S, Piobbico D, Della Fazia MA, Caruso D, De Fabiani E, Benedetti L, Cusella De Angelis MG, Gieselmann V, Servillo G, Beccari T, Roberti R.

FEBS J. 2008 Oct;275(20):5034-47. doi: 10.1111/j.1742-4658.2008.06637.x. Epub 2008 Sep 10.

23.

Plasma oxysterols in normal and cholestatic children as indicators of the two pathways of bile acid synthesis.

Crosignani A, Del Puppo M, De Fabiani E, Caruso D, Gallisai D, Mela MG, Melzi ML, Galli Kienle M, Colombo C.

Clin Chim Acta. 2008 Sep;395(1-2):84-8. doi: 10.1016/j.cca.2008.05.011. Epub 2008 May 19.

PMID:
18538136
24.

Bile acids and gene regulation: from nuclear receptors to chromatin.

Mitro N, Gilardi F, Godio C, Scotti E, De Fabiani E, Caruso D, Crestani M.

Front Biosci. 2008 May 1;13:6276-88. Review.

PMID:
18508660
25.

The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol.

Gilardi F, Mitro N, Godio C, Scotti E, Caruso D, Crestani M, De Fabiani E.

Pharmacol Ther. 2007 Dec;116(3):449-72. Epub 2007 Sep 7. Review.

PMID:
17959250
26.

Bile acids and their signaling pathways: eclectic regulators of diverse cellular functions.

Scotti E, Gilardi F, Godio C, Gers E, Krneta J, Mitro N, De Fabiani E, Caruso D, Crestani M.

Cell Mol Life Sci. 2007 Oct;64(19-20):2477-91. Review.

PMID:
17876519
27.

Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.

Mitro N, Godio C, De Fabiani E, Scotti E, Galmozzi A, Gilardi F, Caruso D, Vigil Chacon AB, Crestani M.

Hepatology. 2007 Sep;46(3):885-97.

PMID:
17654698
28.

Age-related changes in bile acid synthesis and hepatic nuclear receptor expression.

Bertolotti M, Gabbi C, Anzivino C, Crestani M, Mitro N, Del Puppo M, Godio C, De Fabiani E, Macchioni D, Carulli L, Rossi A, Ricchi M, Loria P, Carulli N.

Eur J Clin Invest. 2007 Jun;37(6):501-8.

PMID:
17537158
29.

Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease.

Crosignani A, Del Puppo M, Longo M, De Fabiani E, Caruso D, Zuin M, Podda M, Javitt NB, Kienle MG.

Clin Chim Acta. 2007 Jul;382(1-2):82-8. Epub 2007 Apr 12.

PMID:
17482152
30.

Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.

Dell'Agli M, Fagnani R, Mitro N, Scurati S, Masciadri M, Mussoni L, Galli GV, Bosisio E, Crestani M, De Fabiani E, Tremoli E, Caruso D.

J Agric Food Chem. 2006 May 3;54(9):3259-64.

PMID:
16637682
31.

Decreased hepatic expression of PPAR-gamma coactivator-1 in cholesterol cholelithiasis.

Bertolotti M, Gabbi C, Anzivino C, Mitro N, Godio C, De Fabiani E, Crestani M, Del Puppo M, Ricchi M, Carulli L, Rossi A, Loria P, Carulli N.

Eur J Clin Invest. 2006 Mar;36(3):170-5.

PMID:
16506961
32.

A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis.

Del Puppo M, Crosignani A, Longo M, Zuin M, Podda M, Galli G, De Fabiani E, Ciuffreda P, Santaniello E, Javitt NB, Kienle MG.

Clin Chim Acta. 2005 May;355(1-2):23-31.

PMID:
15820474
33.

Bile acid signaling to the nucleus: finding new connections in the transcriptional regulation of metabolic pathways.

De Fabiani E, Mitro N, Godio C, Gilardi F, Caruso D, Crestani M.

Biochimie. 2004 Nov;86(11):771-8. Review.

PMID:
15589685
34.

LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport.

Crestani M, De Fabiani E, Caruso D, Mitro N, Gilardi F, Vigil Chacon AB, Patelli R, Godio C, Galli G.

Biochem Soc Trans. 2004 Feb;32(Pt 1):92-6. Review.

PMID:
14748721
35.

Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle.

De Fabiani E, Mitro N, Gilardi F, Caruso D, Galli G, Crestani M.

J Biol Chem. 2003 Oct 3;278(40):39124-32. Epub 2003 Jul 15.

36.

Independent factors predict supranormal CA 15-3 serum levels in advanced breast cancer patients at first disease relapse.

Tampellini M, Berruti A, Gorzegno G, Bitossi R, Bottini A, Durando A, De Matteis A, Farris A, Donadio M, De Fabiani E, Manzin E, Arese P, Sarobba MG, Castiglione F, Moro G, Bonazzi G, Nuzzo F, Massobrio M, Dogliotti L.

Tumour Biol. 2001 Nov-Dec;22(6):367-73.

PMID:
11786730
37.

Suppression of bile acid synthesis, but not of hepatic cholesterol 7alpha-hydroxylase expression, by obstructive cholestasis in humans.

Bertolotti M, Carulli L, Concari M, Martella P, Loria P, Tagliafico E, Ferrari S, Del Puppo M, Amati B, De Fabiani E, Crestani M, Amorotti C, Manenti A, Carubbi F, Pinetti A, Carulli N.

Hepatology. 2001 Aug;34(2):234-42.

PMID:
11481606
39.

Identification and characterization of cis-acting elements conferring insulin responsiveness on hamster cholesterol 7alpha-hydroxylase gene promoter.

De Fabiani E, Crestani M, Marrapodi M, Pinelli A, Golfieri V, Galli G.

Biochem J. 2000 Apr 1;347 Pt 1:147-54.

40.
41.

Regulation of the hamster cholesterol 7 alpha-hydroxylase gene (CYP7A): prevalence of negative over positive transcriptional control.

De Fabiani E, Crestani M, Marrapodi M, Pinelli A, Chiang JY, Galli G.

Biochem Biophys Res Commun. 1996 Sep 24;226(3):663-71.

PMID:
8831673
42.

Clinical and biochemical screening for Smith-Lemli-Opitz syndrome. Italian SLOS Collaborative Group.

Guzzetta V, De Fabiani E, Galli G, Colombo C, Corso G, Lecora M, Parenti G, Strisciuglio P, Andria G.

Acta Paediatr. 1996 Aug;85(8):937-42.

PMID:
8863875
43.

Plasma lipoproteins and cholesterol metabolism in Yoshida rats: an animal model of spontaneous hyperlipemia.

Fantappiè S, Catapano AL, Cancellieri M, Fasoli L, De Fabiani E, Bertolini M, Bosisio E.

Life Sci. 1992;50(24):1913-24.

PMID:
1598076
44.

Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes. II.

De Fabiani E, Crestani M, Fasoli L, Bosisio E.

Chem Phys Lipids. 1991 Jan-Feb;57(1):97-101.

PMID:
2060067
45.

Effect of natural and structurally modified bile acids on cholesterol metabolizing enzymes in rat liver microsomes.

Crestani M, De Fabiani E, Malavasi B, Cancellieri M, Galli G, Bosisio E.

Chem Phys Lipids. 1989 Oct;51(2):119-26.

PMID:
2590949
46.

The effect of etofibrate on cholesterol and bile acid metabolism in the hamster.

De Fabiani E, Crestani M, Malavasi B, Del Puppo M, Farina F, Armocida C, Bellentani S, Quack G, Bosisio E.

Pharmacol Res. 1989 Sep-Oct;21(5):567-76.

PMID:
2594613
47.

Alterations in high-density lipoprotein subfractions during postprandial lipidaemia induced by fat with and without ethanol.

Franceschini G, Moreno Y, Apebe P, Calabresi L, Gatti E, Noè D, de Fabiani E, Zoppi F, Sirtori CR.

Clin Sci (Lond). 1988 Aug;75(2):135-42.

PMID:
3409630
48.

Single dose pharmacokinetics of aminoglutethimide by a rapid SIM methodology.

Sirtori CR, De Fabiani E, Caruso D, Malavasi B, Galli G, Galli-Kienle M.

Int J Clin Pharmacol Ther Toxicol. 1988 Aug;26(8):380-4.

PMID:
3220611
49.

Taurine increases bile acid pool size and reduces bile saturation index in the hamster.

Bellentani S, Pecorari M, Cordoma P, Marchegiano P, Manenti F, Bosisio E, De Fabiani E, Galli G.

J Lipid Res. 1987 Sep;28(9):1021-7.

50.

Effect of tauroursodeoxycholate feeding, with or without taurine supplementation on hepatic bile acids and cholesterol metabolism in the hamster.

Bellentani S, Bosisio E, Pecorari M, De Fabiani E, Cordoma P, Crestani M, Manenti F.

Pharmacol Res Commun. 1987 May;19(5):327-39.

PMID:
3628457

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