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1.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y; Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE); Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, O'Donovan MC, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA.

Nat Genet. 2019 Aug 15. doi: 10.1038/s41588-019-0495-7. [Epub ahead of print]

PMID:
31417202
2.

Alzheimer's disease: Neurotransmitters of the sleep-wake cycle.

Van Erum J, Van Dam D, De Deyn PP.

Neurosci Biobehav Rev. 2019 Aug 1;105:72-80. doi: 10.1016/j.neubiorev.2019.07.019. [Epub ahead of print] Review.

3.

Age- and Disease-Specific Changes of the Kynurenine Pathway in Parkinson's and Alzheimer's Disease.

Sorgdrager FJH, Vermeiren Y, Van Faassen HJR, Van Der Ley CP, Nollen EAA, Kema IP, De Deyn PP.

J Neurochem. 2019 Aug 3. doi: 10.1111/jnc.14843. [Epub ahead of print]

PMID:
31376341
4.

The buffering capacity of the brain and optic nerve against spaceflight-associated neuro-ocular syndrome.

Wostyn P, Mader TH, Gibson CR, De Deyn PP.

Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):15770-15771. doi: 10.1073/pnas.1908865116. Epub 2019 Jul 30. No abstract available.

PMID:
31363044
5.

Pre-analytical stability of novel cerebrospinal fluid biomarkers.

Willemse EAJ, Vermeiren Y, Garcia-Ayllon MS, Bridel C, De Deyn PP, Engelborghs S, van der Flier WM, Jansen EEW, Lopez-Font IB, Mendes V, Manadas B, de Roeck N, Saez-Valero J, Struys EA, Vanmechelen E, Andreasson U, Teunissen CE.

Clin Chim Acta. 2019 Jul 23. pii: S0009-8981(19)31974-6. doi: 10.1016/j.cca.2019.07.024. [Epub ahead of print]

PMID:
31348908
6.

Sleep architecture changes in the APP23 mouse model manifest at onset of cognitive deficits.

Van Erum J, Van Dam D, Sheorajpanday R, De Deyn PP.

Behav Brain Res. 2019 Nov 5;373:112089. doi: 10.1016/j.bbr.2019.112089. Epub 2019 Jul 17.

7.

Clinical Considerations in Physician-Assisted Death for Probable Alzheimer's Disease: Decision-Making Capacity, Anosognosia, and Suffering.

Mondragón JD, Salame L, Kraus A, De Deyn PP.

Dement Geriatr Cogn Dis Extra. 2019 Jun 18;9(2):217-226. doi: 10.1159/000500183. eCollection 2019 May-Aug.

8.

Diagnostic performance of regional cerebral blood flow images derived from dynamic PIB scans in Alzheimer's disease.

Peretti DE, Vállez García D, Reesink FE, Doorduin J, de Jong BM, De Deyn PP, Dierckx RAJO, Boellaard R.

EJNMMI Res. 2019 Jul 4;9(1):59. doi: 10.1186/s13550-019-0528-3.

9.

Rapid Reconfiguration of the Functional Connectome after Chemogenetic Locus Coeruleus Activation.

Zerbi V, Floriou-Servou A, Markicevic M, Vermeiren Y, Sturman O, Privitera M, von Ziegler L, Ferrari KD, Weber B, De Deyn PP, Wenderoth N, Bohacek J.

Neuron. 2019 Jun 7. pii: S0896-6273(19)30487-8. doi: 10.1016/j.neuron.2019.05.034. [Epub ahead of print]

PMID:
31227310
10.

Functional Neural Correlates of Anosognosia in Mild Cognitive Impairment and Alzheimer's Disease: a Systematic Review.

Mondragón JD, Maurits NM, De Deyn PP.

Neuropsychol Rev. 2019 Jun;29(2):139-165. doi: 10.1007/s11065-019-09410-x. Epub 2019 Jun 3. Review.

11.

Dementia, End of Life, and Euthanasia: A Survey Among Dementia Specialists Organized by the Belgian Dementia Council.

Picard G, Bier JC, Capron I, De Deyn PP, Deryck O, Engelborghs S, Hanseeuw B, Lemper JC, Mormont E, Petrovic M, Salmon E, Segers K, Sieben A, Thiery E, Ventura M, Versijpt J, Ivanoiu A.

J Alzheimers Dis. 2019;69(4):989-1001. doi: 10.3233/JAD-181277.

PMID:
31127774
12.

Nitric oxide donor molsidomine favors features of atherosclerotic plaque stability and reduces myocardial infarction in mice.

Roth L, Van der Donckt C, Emini Veseli B, Van Dam D, De Deyn PP, Martinet W, Herman AG, De Meyer GRY.

Vascul Pharmacol. 2019 Jul - Aug;118-119:106561. doi: 10.1016/j.vph.2019.05.001. Epub 2019 May 11.

13.

Driving Difficulties Among Patients with Alzheimer's Disease and Other Neurodegenerative Disorders.

Fuermaier ABM, Piersma D, de Waard D, Davidse RJ, de Groot J, Doumen MJA, Bredewoud RA, Claesen R, Lemstra AW, Scheltens P, Vermeeren A, Ponds R, Verhey F, De Deyn PP, Brouwer WH, Tucha O.

J Alzheimers Dis. 2019;69(4):1019-1030. doi: 10.3233/JAD-181095.

PMID:
31045516
14.

Sampling issues of cerebrospinal fluid and plasma monoamines: Investigation of the circadian rhythm and rostrocaudal concentration gradient.

Janssens J, Atmosoerodjo SD, Vermeiren Y, Absalom AR, den Daas I, De Deyn PP.

Neurochem Int. 2019 Sep;128:154-162. doi: 10.1016/j.neuint.2019.04.015. Epub 2019 Apr 26.

15.

PTZ-induced seizures in mice require a revised Racine scale.

Van Erum J, Van Dam D, De Deyn PP.

Epilepsy Behav. 2019 Jun;95:51-55. doi: 10.1016/j.yebeh.2019.02.029. Epub 2019 Apr 24.

16.

Early imaging biomarkers of lung cancer, COPD and coronary artery disease in the general population: rationale and design of the ImaLife (Imaging in Lifelines) Study.

Xia C, Rook M, Pelgrim GJ, Sidorenkov G, Wisselink HJ, van Bolhuis JN, van Ooijen PMA, Guo J, Oudkerk M, Groen H, van den Berge M, van der Harst P, Dijkstra H, Vonder M, Heuvelmans MA, Dorrius MD, De Deyn PP, de Bock GH, Dotinga A, Vliegenthart R.

Eur J Epidemiol. 2019 Apr 23. doi: 10.1007/s10654-019-00519-0. [Epub ahead of print]

PMID:
31016436
17.

Correction: Relative cerebral flow from dynamic PIB scans as an alternative for FDG scans in Alzheimer's disease PET studies.

Peretti DE, Vállez García D, Reesink FE, van der Goot T, De Deyn PP, de Jong BM, Dierckx RAJO, Boellaard R.

PLoS One. 2019 Mar 18;14(3):e0214187. doi: 10.1371/journal.pone.0214187. eCollection 2019.

18.

Validation of the Erlangen Score Algorithm for Differential Dementia Diagnosis in Autopsy-Confirmed Subjects.

Somers C, Lewczuk P, Sieben A, Van Broeckhoven C, De Deyn PP, Kornhuber J, Martin JJ, Bjerke M, Engelborghs S.

J Alzheimers Dis. 2019;68(3):1151-1159. doi: 10.3233/JAD-180563.

19.

Evaluating the applicability of mouse SINEs as an alternative normalization approach for RT-qPCR in brain tissue of the APP23 model for Alzheimer's disease.

Janssens J, Crans RAJ, Van Craenenbroeck K, Vandesompele J, Stove CP, Van Dam D, De Deyn PP.

J Neurosci Methods. 2019 May 15;320:128-137. doi: 10.1016/j.jneumeth.2019.03.005. Epub 2019 Mar 5.

20.

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT Jr, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y, Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, C O'Donovan M, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA; Alzheimer Disease Genetics Consortium (ADGC),; European Alzheimer’s Disease Initiative (EADI),; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE),; Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES),.

Nat Genet. 2019 Mar;51(3):414-430. doi: 10.1038/s41588-019-0358-2. Epub 2019 Feb 28. Erratum in: Nat Genet. 2019 Aug 15;:.

PMID:
30820047
21.

Brief cognitive screening instruments for early detection of Alzheimer's disease: a systematic review.

De Roeck EE, De Deyn PP, Dierckx E, Engelborghs S.

Alzheimers Res Ther. 2019 Feb 28;11(1):21. doi: 10.1186/s13195-019-0474-3. Review.

22.

Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society.

Reeves RH, Delabar J, Potier MC, Bhattacharyya A, Head E, Lemere C, Dekker AD, De Deyn P, Caviedes P, Dierssen M, Busciglio J.

Mol Syndromol. 2019 Jan;9(6):279-286. doi: 10.1159/000494231. Epub 2018 Oct 30.

23.

Targeting TNFR2 as a Novel Therapeutic Strategy for Alzheimer's Disease.

Ortí-Casañ N, Wu Y, Naudé PJW, De Deyn PP, Zuhorn IS, Eisel ULM.

Front Neurosci. 2019 Feb 4;13:49. doi: 10.3389/fnins.2019.00049. eCollection 2019.

24.

Alzheimer's disease and glaucoma: Look-alike neurodegenerative diseases.

Wostyn P, Van Dam D, De Deyn PP.

Alzheimers Dement. 2019 Apr;15(4):600-601. doi: 10.1016/j.jalz.2018.12.012. Epub 2019 Jan 31. No abstract available.

PMID:
30713020
25.

Relative cerebral flow from dynamic PIB scans as an alternative for FDG scans in Alzheimer's disease PET studies.

Peretti DE, Vállez García D, Reesink FE, van der Goot T, De Deyn PP, de Jong BM, Dierckx RAJO, Boellaard R.

PLoS One. 2019 Jan 17;14(1):e0211000. doi: 10.1371/journal.pone.0211000. eCollection 2019. Erratum in: PLoS One. 2019 Mar 18;14(3):e0214187.

26.

The validation of Short Interspersed Nuclear Elements (SINEs) as a RT-qPCR normalization strategy in a rodent model for temporal lobe epilepsy.

Crans RAJ, Janssens J, Daelemans S, Wouters E, Raedt R, Van Dam D, De Deyn PP, Van Craenenbroeck K, Stove CP.

PLoS One. 2019 Jan 10;14(1):e0210567. doi: 10.1371/journal.pone.0210567. eCollection 2019.

27.

Intrathecal cerebrospinal fluid infusion as a potential therapeutic strategy for Alzheimer's disease.

Wostyn P, Van Dam D, De Deyn PP.

Med Hypotheses. 2019 Jan;122:57. doi: 10.1016/j.mehy.2018.10.020. Epub 2018 Oct 22. No abstract available.

PMID:
30593424
28.

Everolimus depletes plaque macrophages, abolishes intraplaque neovascularization and improves survival in mice with advanced atherosclerosis.

Kurdi A, Roth L, Van der Veken B, Van Dam D, De Deyn PP, De Doncker M, Neels H, De Meyer GRY, Martinet W.

Vascul Pharmacol. 2019 Feb;113:70-76. doi: 10.1016/j.vph.2018.12.004. Epub 2018 Dec 24.

PMID:
30590134
29.

Lipocalin 2 contributes to brain iron dysregulation but does not affect cognition, plaque load, and glial activation in the J20 Alzheimer mouse model.

Dekens DW, Naudé PJW, Keijser JN, Boerema AS, De Deyn PP, Eisel ULM.

J Neuroinflammation. 2018 Nov 30;15(1):330. doi: 10.1186/s12974-018-1372-5.

30.

Dilated Prelaminar Paravascular Spaces as a Possible Mechanism for Optic Disc Edema in Astronauts.

Wostyn P, De Winne F, Stern C, De Deyn PP.

Aerosp Med Hum Perform. 2018 Dec 1;89(12):1089-1091. doi: 10.3357/AMHP.5095.2018.

PMID:
30487031
31.

Episodic memory in mild cognitive impairment inversely correlates with the global modularity of the cerebral blood flow network.

Sánchez-Catasús CA, Willemsen A, Boellaard R, Juarez-Orozco LE, Samper-Noa J, Aguila-Ruiz A, De Deyn PP, Dierckx R, Medina YI, Melie-Garcia L.

Psychiatry Res Neuroimaging. 2018 Dec 30;282:73-81. doi: 10.1016/j.pscychresns.2018.11.003. Epub 2018 Nov 3.

PMID:
30419408
32.

The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia.

Piersma D, Fuermaier ABM, de Waard D, De Deyn PP, Davidse RJ, de Groot J, Doumen MJA, Bredewoud RA, Claesen R, Lemstra AW, Vermeeren A, Ponds R, Verhey F, Brouwer WH, Tucha O.

Acta Neurol Belg. 2018 Dec;118(4):637-642. doi: 10.1007/s13760-018-1036-3. Epub 2018 Nov 2.

33.

[The behavioral and psychological symptoms of dementia in down syndrome (BPSD-DS) scale: comprehensive assessment of psychopathology in down syndrome].

Dekker AD, Vermeiren Y, Beugelsdijk G, Schippers M, Hassefras L, Eleveld J, Grefelman S, Fopma R, Bomer-Veenboer M, Oosterling GDE, Scholten E, Tollenaere M, Van Goethem G, Zu Eulenburg C, Coppus AMW, De Deyn PP.

Tijdschr Gerontol Geriatr. 2018 Oct;49(5):187-205. doi: 10.1007/s12439-018-0262-8. Epub 2018 Sep 20. Dutch.

PMID:
30238286
34.

Adherence to driving cessation advice given to patients with cognitive impairment and consequences for mobility.

Piersma D, Fuermaier ABM, De Waard D, Davidse RJ, De Groot J, Doumen MJA, Ponds RWHM, De Deyn PP, Brouwer WH, Tucha O.

BMC Geriatr. 2018 Sep 17;18(1):216. doi: 10.1186/s12877-018-0910-4.

35.

Crossed Cerebellar Diaschisis in Alzheimer's Disease.

Reesink FE, García DV, Sánchez-Catasús CA, Peretti DE, Willemsen AT, Boellaard R, Meles SK, Huitema RB, de Jong BM, Dierckx RA, De Deyn PP.

Curr Alzheimer Res. 2018;15(13):1267-1275. doi: 10.2174/1567205015666180913102615.

PMID:
30210001
36.

Randomized controlled trial to evaluate a prevention program for frail community-dwelling older adults: a D-SCOPE protocol.

Lambotte D, De Donder L, De Roeck EE, Hoeyberghs LJ, van der Vorst A, Duppen D, Van der Elst M, Fret B, Dury S, Smetcoren AS, Kardol MJM, Engelborghs S, De Deyn PP, De Witte N, Schols JMGA, Kempen GIJM, Zijlstra GAR, De Lepeleire J, Schoenmakers B, Verté D, Dierckx E.

BMC Geriatr. 2018 Aug 27;18(1):194. doi: 10.1186/s12877-018-0875-3.

37.

Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.

Vandermeeren M, Borgers M, Van Kolen K, Theunis C, Vasconcelos B, Bottelbergs A, Wintmolders C, Daneels G, Willems R, Dockx K, Delbroek L, Marreiro A, Ver Donck L, Sousa C, Nanjunda R, Lacy E, Van De Casteele T, Van Dam D, De Deyn PP, Kemp JA, Malia TJ, Mercken MH.

J Alzheimers Dis. 2018;65(1):265-281. doi: 10.3233/JAD-180404.

PMID:
30040731
38.

Intracranial pressure and glaucoma: Is there a new therapeutic perspective on the horizon?

Wostyn P, Van Dam D, De Deyn PP.

Med Hypotheses. 2018 Sep;118:98-102. doi: 10.1016/j.mehy.2018.06.026. Epub 2018 Jun 28.

PMID:
30037625
39.

The putative glymphatic signature of chronic fatigue syndrome: A new view on the disease pathogenesis and therapy.

Wostyn P, De Deyn PP.

Med Hypotheses. 2018 Sep;118:142-145. doi: 10.1016/j.mehy.2018.07.007. Epub 2018 Jul 6.

PMID:
30037603
40.

Neuroimaging of Subacute Brain Inflammation and Microstructural Changes Predicts Long-Term Functional Outcome after Experimental Traumatic Brain Injury.

Missault S, Anckaerts C, Blockx I, Deleye S, Van Dam D, Barriche N, De Pauw G, Aertgeerts S, Valkenburg F, De Deyn PP, Verhaeghe J, Wyffels L, Van der Linden A, Staelens S, Verhoye M, Dedeurwaerdere S.

J Neurotrauma. 2019 Mar 1;36(5):768-788. doi: 10.1089/neu.2018.5704. Epub 2018 Oct 3.

PMID:
30032713
41.

No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients.

Baradaran-Heravi Y, Dillen L, Nguyen HP, Van Mossevelde S, Baets J, De Jonghe P, Engelborghs S, De Deyn PP, Vandenbulcke M, Vandenberghe R, Van Damme P, Cras P, Salmon E, Synofzik M, Heutink P, Wilke C, Simon-Sanchez J, Rojas-Garcia R, Turon-Sans J, Lleó A, Illán-Gala I, Clarimón J, Borroni B, Padovani A, Pastor P, Diez-Fairen M, Aguilar M, Gelpi E, Sanchez-Valle R, Borrego-Ecija S, Matej R, Parobkova E, Nacmias B, Sorbi S, Bagnoli S, de Mendonça A, Ferreira C, Fraidakis MJ, Diehl-Schmid J, Alexopoulos P, Almeida MR, Santana I, Van Broeckhoven C, van der Zee J; BELNEU Consortium; EU EOD Consortium.

Neurobiol Aging. 2018 Sep;69:293.e9-293.e11. doi: 10.1016/j.neurobiolaging.2018.05.005. Epub 2018 May 23.

42.

Genetic screening in early-onset dementia patients with unclear phenotype: relevance for clinical diagnosis.

Perrone F, Cacace R, Van Mossevelde S, Van den Bossche T, De Deyn PP, Cras P, Engelborghs S, van der Zee J, Van Broeckhoven C.

Neurobiol Aging. 2018 Sep;69:292.e7-292.e14. doi: 10.1016/j.neurobiolaging.2018.04.015. Epub 2018 May 9.

43.

A Retrospective Belgian Multi-Center MRI Biomarker Study in Alzheimer's Disease (REMEMBER).

Niemantsverdriet E, Ribbens A, Bastin C, Benoit F, Bergmans B, Bier JC, Bladt R, Claes L, De Deyn PP, Deryck O, Hanseeuw B, Ivanoiu A, Lemper JC, Mormont E, Picard G, Salmon E, Segers K, Sieben A, Smeets D, Struyfs H, Thiery E, Tournoy J, Triau E, Vanbinst AM, Versijpt J, Bjerke M, Engelborghs S.

J Alzheimers Dis. 2018;63(4):1509-1522. doi: 10.3233/JAD-171140.

44.

Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease.

Dekker AD, Vermeiren Y, Carmona-Iragui M, Benejam B, Videla L, Gelpi E, Aerts T, Van Dam D, Fernández S, Lleó A, Videla S, Sieben A, Martin JJ; Netherlands Brain Bank, Blesa R, Fortea J, De Deyn PP.

Alzheimers Dement (Amst). 2017 Nov 23;10:99-111. doi: 10.1016/j.dadm.2017.11.001. eCollection 2018.

45.

Letter to the Editor. Low ICP and normal tension glaucoma: optic nerve damage due to barotraumatic factors, failure of CSF dynamics, or both?

Wostyn P, De Groot V, Van Dam D, Audenaert K, De Deyn PP, Killer HE.

J Neurosurg. 2018 Oct;129(4):1100-1103. doi: 10.3171/2017.11.JNS172939. Epub 2018 May 4. No abstract available.

PMID:
29726764
46.

Lower Choline and Myo-Inositol in Temporo-Parietal Cortex Is Associated With Apathy in Amnestic MCI.

Tumati S, Opmeer EM, Marsman JC, Martens S, Reesink FE, De Deyn PP, Aleman A.

Front Aging Neurosci. 2018 Apr 13;10:106. doi: 10.3389/fnagi.2018.00106. eCollection 2018.

47.

Can cerebrospinal fluid diversion be beneficial in the treatment of chronic fatigue syndrome?

Wostyn P, De Deyn PP.

Med Hypotheses. 2018 Sep;118:174. doi: 10.1016/j.mehy.2018.04.020. Epub 2018 Apr 24. No abstract available.

PMID:
29706288
48.

The Behavioral and Psychological Symptoms of Dementia in Down Syndrome (BPSD-DS) Scale: Comprehensive Assessment of Psychopathology in Down Syndrome.

Dekker AD, Sacco S, Carfi A, Benejam B, Vermeiren Y, Beugelsdijk G, Schippers M, Hassefras L, Eleveld J, Grefelman S, Fopma R, Bomer-Veenboer M, Boti M, Oosterling GDE, Scholten E, Tollenaere M, Checkley L, Strydom A, Van Goethem G, Onder G, Blesa R, Zu Eulenburg C, Coppus AMW, Rebillat AS, Fortea J, De Deyn PP.

J Alzheimers Dis. 2018;63(2):797-819. doi: 10.3233/JAD-170920.

49.

The "Ocular Glymphatic System": An Important Missing Piece in the Puzzle of Optic Disc Edema in Astronauts?

Wostyn P, De Deyn PP.

Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):2090-2091. doi: 10.1167/iovs.17-23263. No abstract available.

PMID:
29677371
50.

Clinical variability and onset age modifiers in an extended Belgian GRN founder family.

Wauters E, Van Mossevelde S, Sleegers K, van der Zee J, Engelborghs S, Sieben A, Vandenberghe R, Philtjens S, Van den Broeck M, Peeters K, Cuijt I, De Coster W, Van Langenhove T, Santens P, Ivanoiu A, Cras P, De Bleecker JL, Versijpt J, Crols R, De Klippel N, Martin JJ, De Deyn PP, Cruts M, Van Broeckhoven C; Belgian Neurology (BELNEU) Consortium.

Neurobiol Aging. 2018 Jul;67:84-94. doi: 10.1016/j.neurobiolaging.2018.03.007. Epub 2018 Mar 10.

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