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Items: 26

1.

A llama-derived gelsolin single-domain antibody blocks gelsolin-G-actin interaction.

Van den Abbeele A, De Clercq S, De Ganck A, De Corte V, Van Loo B, Soror SH, Srinivasan V, Steyaert J, Vandekerckhove J, Gettemans J.

Cell Mol Life Sci. 2010 May;67(9):1519-35. doi: 10.1007/s00018-010-0266-1. Epub 2010 Feb 7.

PMID:
20140750
2.

Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells.

De Ganck A, De Corte V, Bruyneel E, Bracke M, Vandekerckhove J, Gettemans J.

Int J Oncol. 2009 May;34(5):1403-9.

PMID:
19360353
3.

Multiple isoforms of the tumor suppressor myopodin are simultaneously transcribed in cancer cells.

De Ganck A, De Corte V, Staes A, Gevaert K, Vandekerckhove J, Gettemans J.

Biochem Biophys Res Commun. 2008 May 30;370(2):269-73. doi: 10.1016/j.bbrc.2008.03.086. Epub 2008 Mar 25.

PMID:
18371299
4.

A new role for nuclear transport factor 2 and Ran: nuclear import of CapG.

Van Impe K, Hubert T, De Corte V, Vanloo B, Boucherie C, Vandekerckhove J, Gettemans J.

Traffic. 2008 May;9(5):695-707. doi: 10.1111/j.1600-0854.2008.00720.x. Epub 2008 Feb 7.

5.

Downregulation of gelsolin family proteins counteracts cancer cell invasion in vitro.

Van den Abbeele A, De Corte V, Van Impe K, Bruyneel E, Boucherie C, Bracke M, Vandekerckhove J, Gettemans J.

Cancer Lett. 2007 Sep 18;255(1):57-70. Epub 2007 May 9.

PMID:
17493746
6.

Phosphorylation on Ser5 increases the F-actin-binding activity of L-plastin and promotes its targeting to sites of actin assembly in cells.

Janji B, Giganti A, De Corte V, Catillon M, Bruyneel E, Lentz D, Plastino J, Gettemans J, Friederich E.

J Cell Sci. 2006 May 1;119(Pt 9):1947-60.

7.

A monopartite nuclear localization sequence regulates nuclear targeting of the actin binding protein myopodin.

De Ganck A, Hubert T, Van Impe K, Geelen D, Vandekerckhove J, De Corte V, Gettemans J.

FEBS Lett. 2005 Dec 5;579(29):6673-80. Epub 2005 Nov 17.

8.

Nuclear actin-binding proteins as modulators of gene transcription.

Gettemans J, Van Impe K, Delanote V, Hubert T, Vandekerckhove J, De Corte V.

Traffic. 2005 Oct;6(10):847-57. Review.

9.

Molecular basis for dissimilar nuclear trafficking of the actin-bundling protein isoforms T- and L-plastin.

Delanote V, Van Impe K, De Corte V, Bruyneel E, Vetter G, Boucherie C, Mareel M, Vandekerckhove J, Friederich E, Gettemans J.

Traffic. 2005 Apr;6(4):335-45.

10.

Increased importin-beta-dependent nuclear import of the actin modulating protein CapG promotes cell invasion.

De Corte V, Van Impe K, Bruyneel E, Boucherie C, Mareel M, Vandekerckhove J, Gettemans J.

J Cell Sci. 2004 Oct 15;117(Pt 22):5283-92. Epub 2004 Sep 28.

11.

YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.

Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, Gettemans J, Barr FA.

J Cell Biol. 2004 Mar 29;164(7):1009-20. Epub 2004 Mar 22.

12.

Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility.

Oliveira MJ, Van Damme J, Lauwaet T, De Corte V, De Bruyne G, Verschraegen G, Vaneechoutte M, Goethals M, Ahmadian MR, Müller O, Vandekerckhove J, Mareel M, Leroy A.

EMBO J. 2003 Nov 17;22(22):6161-73.

13.

A kelch beta propeller featuring as a G beta structural mimic: reinventing the wheel?

Gettemans J, Meerschaert K, Vandekerckhove J, De Corte V.

Sci STKE. 2003 Jul 15;2003(191):PE27. Review.

PMID:
12865498
14.

The Nucleo-cytoplasmic actin-binding protein CapG lacks a nuclear export sequence present in structurally related proteins.

Van Impe K, De Corte V, Eichinger L, Bruyneel E, Mareel M, Vandekerckhove J, Gettemans J.

J Biol Chem. 2003 May 16;278(20):17945-52. Epub 2003 Mar 11.

15.

Gelsolin-induced epithelial cell invasion is dependent on Ras-Rac signaling.

De Corte V, Bruyneel E, Boucherie C, Mareel M, Vandekerckhove J, Gettemans J.

EMBO J. 2002 Dec 16;21(24):6781-90.

16.

Fragmin60 encodes an actin-binding protein with a C2 domain and controls actin Thr-203 phosphorylation in Physarum plasmodia and sclerotia.

Sklyarova T, De Corte V, Meerschaert K, Devriendt L, Vanloo B, Bailey J, Cook LJ, Goethals M, Van Damme J, Puype M, Vandekerckhove J, Gettemans J.

J Biol Chem. 2002 Oct 18;277(42):39840-9. Epub 2002 Aug 7.

17.

Selected BTB/POZ-kelch proteins bind ATP.

T'Jampens D, Devriendt L, De Corte V, Vandekerckhove J, Gettemans J.

FEBS Lett. 2002 Apr 10;516(1-3):20-6.

18.

A novel endogenous PP2C-like phosphatase dephosphorylates casein kinase II-phosphorylated Physarum fragmin.

Waelkens E, de Corte V, Merlevede W, Vandekerckhove J, Gettemans J.

Biochem Biophys Res Commun. 2000 Dec 20;279(2):438-44.

PMID:
11118305
19.

Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: a mass spectrometric approach.

De Corte V, Demol H, Goethals M, Van Damme J, Gettemans J, Vandekerckhove J.

Protein Sci. 1999 Jan;8(1):234-41.

20.

Gelsolin and functionally similar actin-binding proteins are regulated by lysophosphatidic acid.

Meerschaert K, De Corte V, De Ville Y, Vandekerckhove J, Gettemans J.

EMBO J. 1998 Oct 15;17(20):5923-32.

21.

Molecular cloning, over-expression, developmental regulation and immunolocalization of fragminP, a gelsolin-related actin-binding protein from Physarum polycephalum plasmodia.

T'Jampens D, Meerschaert K, Constantin B, Bailey J, Cook LJ, De Corte V, De Mol H, Goethals M, Van Damme J, Vandekerckhove J, Gettemans J.

J Cell Sci. 1997 May;110 ( Pt 10):1215-26.

22.
23.

In vivo phosphorylation of actin in Physarum polycephalum. Study of the substrate specificity of the actin-fragmin kinase.

De Corte V, Gettemans J, Waelkens E, Vandekerckhove J.

Eur J Biochem. 1996 Nov 1;241(3):901-8.

24.

Fragmin, a microfilament regulatory protein from Physarum polycephalum, is phosphorylated by casein kinase II-type enzymes.

De Corte V, Gettemans J, De Ville Y, Waelkens E, Vandekerckhove J.

Biochemistry. 1996 Apr 30;35(17):5472-80.

PMID:
8611538
25.

Microfilament dynamics: regulation of actin polymerization by actin-fragmin kinase and phosphatases.

Waelkens E, Gettemans J, De Corte V, De Ville Y, Goris J, Vandekerckhove J, Merlevede W.

Adv Enzyme Regul. 1995;35:199-227. Review.

PMID:
7572344
26.

A 50 kDa protein present in conditioned medium of COLO-16 cells stimulates cell spreading and motility, and activates tyrosine phosphorylation of Neu/HER-2, in human SK-BR-3 mammary cancer cells.

De Corte V, De Potter C, Vandenberghe D, Van Laerebeke N, Azam M, Roels H, Mareel M, Vandekerckhove J.

J Cell Sci. 1994 Mar;107 ( Pt 3):405-16.

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