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Items: 1 to 50 of 367

1.

Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum.

Luscher A, Fröhlich F, Barisch C, Littlewood C, Metcalfe J, Leuba F, Palma A, Pirruccello M, Cesareni G, Stagi M, Walther TC, Soldati T, De Camilli P, Swan LE.

Mol Biol Cell. 2019 Jun 19:mbcE18080510. doi: 10.1091/mbc.E18-08-0510. [Epub ahead of print]

PMID:
31216233
2.

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse.

Koopmans F, van Nierop P, Andres-Alonso M, Byrnes A, Cijsouw T, Coba MP, Cornelisse LN, Farrell RJ, Goldschmidt HL, Howrigan DP, Hussain NK, Imig C, de Jong APH, Jung H, Kohansalnodehi M, Kramarz B, Lipstein N, Lovering RC, MacGillavry H, Mariano V, Mi H, Ninov M, Osumi-Sutherland D, Pielot R, Smalla KH, Tang H, Tashman K, Toonen RFG, Verpelli C, Reig-Viader R, Watanabe K, van Weering J, Achsel T, Ashrafi G, Asi N, Brown TC, De Camilli P, Feuermann M, Foulger RE, Gaudet P, Joglekar A, Kanellopoulos A, Malenka R, Nicoll RA, Pulido C, de Juan-Sanz J, Sheng M, Südhof TC, Tilgner HU, Bagni C, Bayés À, Biederer T, Brose N, Chua JJE, Dieterich DC, Gundelfinger ED, Hoogenraad C, Huganir RL, Jahn R, Kaeser PS, Kim E, Kreutz MR, McPherson PS, Neale BM, O'Connor V, Posthuma D, Ryan TA, Sala C, Feng G, Hyman SE, Thomas PD, Smit AB, Verhage M.

Neuron. 2019 May 22. pii: S0896-6273(19)30427-1. doi: 10.1016/j.neuron.2019.05.002. [Epub ahead of print]

PMID:
31171447
3.

Paul Greengard (1925-2019).

De Camilli P.

Science. 2019 May 24;364(6442):740. doi: 10.1126/science.aax9357. No abstract available.

PMID:
31123127
4.

Lipid transporter TMEM24/C2CD2L is a Ca2+-regulated component of ER-plasma membrane contacts in mammalian neurons.

Sun EW, Guillén-Samander A, Bian X, Wu Y, Cai Y, Messa M, De Camilli P.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5775-5784. doi: 10.1073/pnas.1820156116. Epub 2019 Feb 28.

PMID:
30819882
5.

In Vitro Assays to Measure the Membrane Tethering and Lipid Transport Activities of the Extended Synaptotagmins.

Bian X, De Camilli P.

Methods Mol Biol. 2019;1949:201-212. doi: 10.1007/978-1-4939-9136-5_15.

6.

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.

Kumar N, Leonzino M, Hancock-Cerutti W, Horenkamp FA, Li P, Lees JA, Wheeler H, Reinisch KM, De Camilli P.

J Cell Biol. 2018 Oct 1;217(10):3625-3639. doi: 10.1083/jcb.201807019. Epub 2018 Aug 9.

7.

The inositol 5-phosphatase INPP5K participates in the fine control of ER organization.

Dong R, Zhu T, Benedetti L, Gowrishankar S, Deng H, Cai Y, Wang X, Shen K, De Camilli P.

J Cell Biol. 2018 Oct 1;217(10):3577-3592. doi: 10.1083/jcb.201802125. Epub 2018 Aug 7.

8.

Kv2 potassium channels meet VAP.

Sun EW, De Camilli P.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):7849-7851. doi: 10.1073/pnas.1810059115. Epub 2018 Jul 17. No abstract available.

9.

A liquid phase of synapsin and lipid vesicles.

Milovanovic D, Wu Y, Bian X, De Camilli P.

Science. 2018 Aug 10;361(6402):604-607. doi: 10.1126/science.aat5671. Epub 2018 Jul 5.

10.

Light-activated protein interaction with high spatial subcellular confinement.

Benedetti L, Barentine AES, Messa M, Wheeler H, Bewersdorf J, De Camilli P.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2238-E2245. doi: 10.1073/pnas.1713845115. Epub 2018 Feb 20.

11.

A lentiviral system for efficient knockdown of proteins in neuronal cultures [version 1; referees: 2 approved].

Ritter B, Ferguson SM, De Camilli P, McPherson PS.

MNI Open Res. 2017;1(2). doi: 10.12688/mniopenres.12766.1. Epub 2017 Dec 5.

12.

Architecture of the human PI4KIIIα lipid kinase complex.

Lees JA, Zhang Y, Oh MS, Schauder CM, Yu X, Baskin JM, Dobbs K, Notarangelo LD, De Camilli P, Walz T, Reinisch KM.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13720-13725. doi: 10.1073/pnas.1718471115. Epub 2017 Dec 11.

13.

Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport.

Bian X, Saheki Y, De Camilli P.

EMBO J. 2018 Jan 17;37(2):219-234. doi: 10.15252/embj.201797359. Epub 2017 Dec 8.

14.

Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers.

Stefan CJ, Trimble WS, Grinstein S, Drin G, Reinisch K, De Camilli P, Cohen S, Valm AM, Lippincott-Schwartz J, Levine TP, Iaea DB, Maxfield FR, Futter CE, Eden ER, Judith D, van Vliet AR, Agostinis P, Tooze SA, Sugiura A, McBride HM.

BMC Biol. 2017 Oct 31;15(1):102. doi: 10.1186/s12915-017-0432-0.

15.

Single-molecule force spectroscopy of protein-membrane interactions.

Ma L, Cai Y, Li Y, Jiao J, Wu Z, O'Shaughnessy B, De Camilli P, Karatekin E, Zhang Y.

Elife. 2017 Oct 30;6. pii: e30493. doi: 10.7554/eLife.30493.

16.

Structural inhibition of dynamin-mediated membrane fission by endophilin.

Hohendahl A, Talledge N, Galli V, Shen PS, Humbert F, De Camilli P, Frost A, Roux A.

Elife. 2017 Sep 21;6. pii: e26856. doi: 10.7554/eLife.26856.

17.

Contacts between the endoplasmic reticulum and other membranes in neurons.

Wu Y, Whiteus C, Xu CS, Hayworth KJ, Weinberg RJ, Hess HF, De Camilli P.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4859-E4867. doi: 10.1073/pnas.1701078114. Epub 2017 May 30.

18.

Loss of Dynamin 2 GTPase function results in microcytic anaemia.

Brown FC, Collett M, Tremblay CS, Rank G, De Camilli P, Booth CJ, Bitoun M, Robinson PJ, Kile BT, Jane SM, Curtis DJ.

Br J Haematol. 2017 Aug;178(4):616-628. doi: 10.1111/bjh.14709. Epub 2017 May 3.

PMID:
28466468
19.

The Extended-Synaptotagmins.

Saheki Y, De Camilli P.

Biochim Biophys Acta Mol Cell Res. 2017 Sep;1864(9):1490-1493. doi: 10.1016/j.bbamcr.2017.03.013. Epub 2017 Mar 28. Review.

20.

Endoplasmic Reticulum-Plasma Membrane Contact Sites.

Saheki Y, De Camilli P.

Annu Rev Biochem. 2017 Jun 20;86:659-684. doi: 10.1146/annurev-biochem-061516-044932. Epub 2017 Feb 23. Review.

PMID:
28301744
21.

Synaptic Vesicle Clusters at Synapses: A Distinct Liquid Phase?

Milovanovic D, De Camilli P.

Neuron. 2017 Mar 8;93(5):995-1002. doi: 10.1016/j.neuron.2017.02.013. Review.

22.

Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons.

Cao M, Wu Y, Ashrafi G, McCartney AJ, Wheeler H, Bushong EA, Boassa D, Ellisman MH, Ryan TA, De Camilli P.

Neuron. 2017 Feb 22;93(4):882-896.e5. doi: 10.1016/j.neuron.2017.01.019.

23.

Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion.

Lees JA, Messa M, Sun EW, Wheeler H, Torta F, Wenk MR, De Camilli P, Reinisch KM.

Science. 2017 Feb 17;355(6326). pii: eaah6171. doi: 10.1126/science.aah6171.

24.

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis.

Levin R, Hammond GR, Balla T, De Camilli P, Fairn GD, Grinstein S.

Mol Biol Cell. 2017 Jan 1;28(1):128-140. doi: 10.1091/mbc.E16-06-0451. Epub 2016 Nov 9.

25.

Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy.

Inoue K, Balkin DM, Liu L, Nandez R, Wu Y, Tian X, Wang T, Nussbaum R, De Camilli P, Ishibe S.

J Am Soc Nephrol. 2017 May;28(5):1399-1407. doi: 10.1681/ASN.2016080913. Epub 2016 Nov 28.

26.

Membrane fission by dynamin: what we know and what we need to know.

Antonny B, Burd C, De Camilli P, Chen E, Daumke O, Faelber K, Ford M, Frolov VA, Frost A, Hinshaw JE, Kirchhausen T, Kozlov MM, Lenz M, Low HH, McMahon H, Merrifield C, Pollard TD, Robinson PJ, Roux A, Schmid S.

EMBO J. 2016 Nov 2;35(21):2270-2284. Epub 2016 Sep 26. Review.

27.

Loss of SYNJ1 dual phosphatase activity leads to early onset refractory seizures and progressive neurological decline.

Hardies K, Cai Y, Jardel C, Jansen AC, Cao M, May P, Djémié T, Hachon Le Camus C, Keymolen K, Deconinck T, Bhambhani V, Long C, Sajan SA, Helbig KL; AR working group of the EuroEPINOMICS RES Consortium, Suls A, Balling R, Helbig I, De Jonghe P, Depienne C, De Camilli P, Weckhuysen S.

Brain. 2016 Sep;139(Pt 9):2420-30. doi: 10.1093/brain/aww180. Epub 2016 Jul 19.

28.

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P.

Dong R, Saheki Y, Swarup S, Lucast L, Harper JW, De Camilli P.

Cell. 2016 Jul 14;166(2):408-423. doi: 10.1016/j.cell.2016.06.037.

29.

The endocytic activity of the flagellar pocket in Trypanosoma brucei is regulated by an adjacent phosphatidylinositol phosphate kinase.

Demmel L, Schmidt K, Lucast L, Havlicek K, Zankel A, Koestler T, Reithofer V, de Camilli P, Warren G.

J Cell Sci. 2016 Jun 1;129(11):2285. doi: 10.1242/jcs.191569. No abstract available.

30.

Control of plasma membrane lipid homeostasis by the extended synaptotagmins.

Saheki Y, Bian X, Schauder CM, Sawaki Y, Surma MA, Klose C, Pincet F, Reinisch KM, De Camilli P.

Nat Cell Biol. 2016 May;18(5):504-15. doi: 10.1038/ncb3339. Epub 2016 Apr 11.

31.

SMP-domain proteins at membrane contact sites: Structure and function.

Reinisch KM, De Camilli P.

Biochim Biophys Acta. 2016 Aug;1861(8 Pt B):924-927. doi: 10.1016/j.bbalip.2015.12.003. Epub 2015 Dec 10. Review.

32.

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.

Baskin JM, Wu X, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, Reinisch KM, De Camilli P.

Nat Cell Biol. 2016 Jan;18(1):132-8. doi: 10.1038/ncb3271. Epub 2015 Nov 16.

33.

INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.

Chung J, Torta F, Masai K, Lucast L, Czapla H, Tanner LB, Narayanaswamy P, Wenk MR, Nakatsu F, De Camilli P.

Science. 2015 Jul 24;349(6246):428-32. doi: 10.1126/science.aab1370.

34.

Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.

Idevall-Hagren O, Lü A, Xie B, De Camilli P.

EMBO J. 2015 Sep 2;34(17):2291-305. doi: 10.15252/embj.201591565. Epub 2015 Jul 22.

35.

The BioPlex Network: A Systematic Exploration of the Human Interactome.

Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, Erickson BK, Wühr M, Chick J, Zhai B, Kolippakkam D, Mintseris J, Obar RA, Harris T, Artavanis-Tsakonas S, Sowa ME, De Camilli P, Paulo JA, Harper JW, Gygi SP.

Cell. 2015 Jul 16;162(2):425-440. doi: 10.1016/j.cell.2015.06.043.

36.

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques.

Gowrishankar S, Yuan P, Wu Y, Schrag M, Paradise S, Grutzendler J, De Camilli P, Ferguson SM.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3699-708. doi: 10.1073/pnas.1510329112. Epub 2015 Jun 29.

37.

Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.

Nakatsu F, Messa M, Nández R, Czapla H, Zou Y, Strittmatter SM, De Camilli P.

J Cell Biol. 2015 Apr 13;209(1):85-95. doi: 10.1083/jcb.201409064.

38.

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes.

Willinger T, Staron M, Ferguson SM, De Camilli P, Flavell RA.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4423-8. doi: 10.1073/pnas.1504279112. Epub 2015 Mar 23.

39.

Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum-plasma membrane contact sites.

Fernández-Busnadiego R, Saheki Y, De Camilli P.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2004-13. doi: 10.1073/pnas.1503191112. Epub 2015 Mar 18.

40.

Preface.

De Matteis A, De Camilli P.

Biochim Biophys Acta. 2015 Jun;1851(6):697. doi: 10.1016/j.bbalip.2015.02.009. Epub 2015 Feb 18. No abstract available.

PMID:
25701448
41.

Plasticity of PI4KIIIα interactions at the plasma membrane.

Chung J, Nakatsu F, Baskin JM, De Camilli P.

EMBO Rep. 2015 Mar;16(3):312-20. doi: 10.15252/embr.201439151. Epub 2015 Jan 21.

42.

Detection and manipulation of phosphoinositides.

Idevall-Hagren O, De Camilli P.

Biochim Biophys Acta. 2015 Jun;1851(6):736-45. doi: 10.1016/j.bbalip.2014.12.008. Epub 2014 Dec 13. Review.

43.

Upregulation of Parkin in endophilin mutant mice.

Cao M, Milosevic I, Giovedi S, De Camilli P.

J Neurosci. 2014 Dec 3;34(49):16544-9. doi: 10.1523/JNEUROSCI.1710-14.2014.

44.

Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts.

Shin NY, Choi H, Neff L, Wu Y, Saito H, Ferguson SM, De Camilli P, Baron R.

J Cell Biol. 2014 Oct 13;207(1):73-89. doi: 10.1083/jcb.201401137. Epub 2014 Oct 6.

45.

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.

Messa M, Fernández-Busnadiego R, Sun EW, Chen H, Czapla H, Wrasman K, Wu Y, Ko G, Ross T, Wendland B, De Camilli P.

Elife. 2014 Aug 13;3:e03311. doi: 10.7554/eLife.03311.

46.

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells.

Nández R, Balkin DM, Messa M, Liang L, Paradise S, Czapla H, Hein MY, Duncan JS, Mann M, De Camilli P.

Elife. 2014 Aug 8;3:e02975. doi: 10.7554/eLife.02975.

47.

The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.

Hubber A, Arasaki K, Nakatsu F, Hardiman C, Lambright D, De Camilli P, Nagai H, Roy CR.

PLoS Pathog. 2014 Jul 3;10(7):e1004222. doi: 10.1371/journal.ppat.1004222. eCollection 2014 Jul.

48.

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.

Wu Y, O'Toole ET, Girard M, Ritter B, Messa M, Liu X, McPherson PS, Ferguson SM, De Camilli P.

Elife. 2014 Jun 24;3:e01621. doi: 10.7554/eLife.01621.

49.

Coupling between endocytosis and sphingosine kinase 1 recruitment.

Shen H, Giordano F, Wu Y, Chan J, Zhu C, Milosevic I, Wu X, Yao K, Chen B, Baumgart T, Sieburth D, De Camilli P.

Nat Cell Biol. 2014 Jul;16(7):652-62. doi: 10.1038/ncb2987. Epub 2014 Jun 15.

50.

Rare deleterious mutations of the gene EFR3A in autism spectrum disorders.

Gupta AR, Pirruccello M, Cheng F, Kang HJ, Fernandez TV, Baskin JM, Choi M, Liu L, Ercan-Sencicek AG, Murdoch JD, Klei L, Neale BM, Franjic D, Daly MJ, Lifton RP, De Camilli P, Zhao H, Sestan N, State MW.

Mol Autism. 2014 Apr 29;5:31. doi: 10.1186/2040-2392-5-31. eCollection 2014.

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