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Items: 17

1.

Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor.

Zhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, Goldstein SAN.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11847-E11856. doi: 10.1073/pnas.1816189115. Epub 2018 Nov 26.

PMID:
30478045
2.

Live imaging of cortical granule exocytosis reveals that in vitro matured mouse oocytes are not fully competent to secrete their content.

Cappa AI, de Paola M, Wetten P, De Blas GA, Michaut MA.

Biol Open. 2018 Dec 3;7(12). pii: bio031872. doi: 10.1242/bio.031872.

3.

ADP ribosylation factor 6 (ARF6) promotes acrosomal exocytosis by modulating lipid turnover and Rab3A activation.

Pelletán LE, Suhaiman L, Vaquer CC, Bustos MA, De Blas GA, Vitale N, Mayorga LS, Belmonte SA.

J Biol Chem. 2015 Apr 10;290(15):9823-41. doi: 10.1074/jbc.M114.629006. Epub 2015 Feb 20.

4.

Kinetics of human sperm acrosomal exocytosis.

Sosa CM, Pavarotti MA, Zanetti MN, Zoppino FC, De Blas GA, Mayorga LS.

Mol Hum Reprod. 2015 Mar;21(3):244-54. doi: 10.1093/molehr/gau110. Epub 2014 Dec 1.

PMID:
25452326
5.

Perfringolysin O as a useful tool to study human sperm physiology.

Pocognoni CA, De Blas GA, Heuck AP, Belmonte SA, Mayorga LS.

Fertil Steril. 2013 Jan;99(1):99-106. doi: 10.1016/j.fertnstert.2012.08.052. Epub 2012 Sep 19.

PMID:
22999796
6.

Diacylglycerol stimulates acrosomal exocytosis by feeding into a PKC- and PLD1-dependent positive loop that continuously supplies phosphatidylinositol 4,5-bisphosphate.

Lopez CI, Pelletán LE, Suhaiman L, De Blas GA, Vitale N, Mayorga LS, Belmonte SA.

Biochim Biophys Acta. 2012 Sep;1821(9):1186-99. doi: 10.1016/j.bbalip.2012.05.001. Epub 2012 May 18.

PMID:
22609963
7.

The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa: differences from the zona pellucida.

Chávez JC, de Blas GA, de la Vega-Beltrán JL, Nishigaki T, Chirinos M, González-González ME, Larrea F, Solís A, Darszon A, Treviño CL.

Asian J Androl. 2011 Jan;13(1):159-65. doi: 10.1038/aja.2010.80. Epub 2010 Sep 13.

8.

Sphingosine 1-phosphate and sphingosine kinase are involved in a novel signaling pathway leading to acrosomal exocytosis.

Suhaiman L, De Blas GA, Obeid LM, Darszon A, Mayorga LS, Belmonte SA.

J Biol Chem. 2010 May 21;285(21):16302-14. doi: 10.1074/jbc.M109.072439. Epub 2010 Mar 17.

9.

TRPM8, a versatile channel in human sperm.

De Blas GA, Darszon A, Ocampo AY, Serrano CJ, Castellano LE, Hernández-González EO, Chirinos M, Larrea F, Beltrán C, Treviño CL.

PLoS One. 2009 Jun 30;4(6):e6095. doi: 10.1371/journal.pone.0006095.

10.

Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis.

Branham MT, Bustos MA, De Blas GA, Rehmann H, Zarelli VE, Treviño CL, Darszon A, Mayorga LS, Tomes CN.

J Biol Chem. 2009 Sep 11;284(37):24825-39. doi: 10.1074/jbc.M109.015362. Epub 2009 Jun 22.

11.

Sperm from hyh mice carrying a point mutation in alphaSNAP have a defect in acrosome reaction.

Bátiz LF, De Blas GA, Michaut MA, Ramírez AR, Rodríguez F, Ratto MH, Oliver C, Tomes CN, Rodríguez EM, Mayorga LS.

PLoS One. 2009;4(3):e4963. doi: 10.1371/journal.pone.0004963. Epub 2009 Mar 23.

12.

Membrane-permeant Rab3A triggers acrosomal exocytosis in living human sperm.

Lopez CI, Belmonte SA, De Blas GA, Mayorga LS.

FASEB J. 2007 Dec;21(14):4121-30. Epub 2007 Jul 11.

PMID:
17625073
13.

Complexin/synaptotagmin interplay controls acrosomal exocytosis.

Roggero CM, De Blas GA, Dai H, Tomes CN, Rizo J, Mayorga LS.

J Biol Chem. 2007 Sep 7;282(36):26335-43. Epub 2007 Jul 4.

14.

Dynamics of SNARE assembly and disassembly during sperm acrosomal exocytosis.

De Blas GA, Roggero CM, Tomes CN, Mayorga LS.

PLoS Biol. 2005 Oct;3(10):e323. Epub 2005 Sep 6.

15.

Protein kinase C-mediated phosphorylation of the two polybasic regions of synaptotagmin VI regulates their function in acrosomal exocytosis.

Roggero CM, Tomes CN, De Blas GA, Castillo J, Michaut MA, Fukuda M, Mayorga LS.

Dev Biol. 2005 Sep 15;285(2):422-35.

16.

Cholesterol content regulates acrosomal exocytosis by enhancing Rab3A plasma membrane association.

Belmonte SA, López CI, Roggero CM, De Blas GA, Tomes CN, Mayorga LS.

Dev Biol. 2005 Sep 15;285(2):393-408.

17.

alpha-SNAP and NSF are required in a priming step during the human sperm acrosome reaction.

Tomes CN, De Blas GA, Michaut MA, Farré EV, Cherhitin O, Visconti PE, Mayorga LS.

Mol Hum Reprod. 2005 Jan;11(1):43-51. Epub 2004 Nov 12.

PMID:
15542541

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