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Items: 1 to 50 of 275

1.

The effect of reactive oxygen and nitrogen species on the structure of cytoglobin: A potential tumor suppressor.

De Backer J, Razzokov J, Hammerschmid D, Mensch C, Hafideddine Z, Kumar N, van Raemdonck G, Yusupov M, Van Doorslaer S, Johannessen C, Sobott F, Bogaerts A, Dewilde S.

Redox Biol. 2018 Jul 24;19:1-10. doi: 10.1016/j.redox.2018.07.019. [Epub ahead of print]

2.

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection.

Renard M, Francis C, Ghosh R, Scott AF, Witmer PD, Adès LC, Andelfinger GU, Arnaud P, Boileau C, Callewaert BL, Guo D, Hanna N, Lindsay ME, Morisaki H, Morisaki T, Pachter N, Robert L, Van Laer L, Dietz HC, Loeys BL, Milewicz DM, De Backer J.

J Am Coll Cardiol. 2018 Aug 7;72(6):605-615. doi: 10.1016/j.jacc.2018.04.089.

PMID:
30071989
3.

Hepatic Changes in the Fontan Circulation: Identification of Liver Dysfunction and an Attempt to Streamline Follow-up Screening.

Ackerman T, Geerts A, Van Vlierberghe H, De Backer J, François K.

Pediatr Cardiol. 2018 Jul 21. doi: 10.1007/s00246-018-1937-1. [Epub ahead of print]

PMID:
30032312
4.

Deletion of Maged1 in mice abolishes locomotor and reinforcing effects of cocaine.

De Backer JF, Monlezun S, Detraux B, Gazan A, Vanopdenbosch L, Cheron J, Cannazza G, Valverde S, Cantacorps L, Nassar M, Venance L, Valverde O, Faure P, Zoli M, De Backer O, Gall D, Schiffmann SN, de Kerchove d'Exaerde A.

EMBO Rep. 2018 Jul 12. pii: e45089. doi: 10.15252/embr.201745089. [Epub ahead of print]

PMID:
30002119
5.

Computed Tomographic Biomarkers in Idiopathic Pulmonary Fibrosis: The Future of Quantitative Analysis.

Wu X, Kim GH, Salisbury ML, Barber D, Bartholmai BJ, Brown KK, Conoscenti CS, De Backer J, Flaherty KR, Gruden JF, Hoffman EA, Humphries SM, Jacob J, Maher TM, Raghu G, Richeldi L, Ross BD, Schlenker-Herceg R, Sverzellati N, Wells AU, Martinez FJ, Lynch DA, Goldin J, Walsh SLF.

Am J Respir Crit Care Med. 2018 Jul 9. doi: 10.1164/rccm.201803-0444PP. [Epub ahead of print]

6.

Predictors of Rapid Aortic Root Dilation and Referral for Aortic Surgery in Marfan Syndrome.

Hoskoppal A, Menon S, Trachtenberg F, Burns KM, De Backer J, Gelb BD, Gleason M, James J, Lai WW, Liou A, Mahony L, Olson AK, Pyeritz RE, Sharkey AM, Stylianou M, Wechsler SB, Young L, Levine JC, Tierney ESS, Lacro RV, Bradley TJ; Pediatric Heart Network Investigators.

Pediatr Cardiol. 2018 Jun 11. doi: 10.1007/s00246-018-1916-6. [Epub ahead of print]

PMID:
29948025
7.

A heart for fibrillin: spatial arrangement in adult wild-type murine myocardial tissue.

Steijns F, van Hengel J, Sips P, De Backer J, Renard M.

Histochem Cell Biol. 2018 Jun 20. doi: 10.1007/s00418-018-1686-5. [Epub ahead of print]

PMID:
29926163
8.

Functional respiratory imaging: heterogeneity of acute exacerbations of COPD.

van Geffen WH, Hajian B, Vos W, De Backer J, Cahn A, Usmani OS, Van Holsbeke C, Pistolesi M, Kerstjens HA, De Backer W.

Int J Chron Obstruct Pulmon Dis. 2018 May 30;13:1783-1792. doi: 10.2147/COPD.S152463. eCollection 2018.

9.

Tailoring the American College of Medical Genetics and Genomics and the Association for Molecular Pathology Guidelines for the Interpretation of Sequenced Variants in the FBN1 Gene for Marfan Syndrome: Proposal for a Disease- and Gene-Specific Guideline.

Muiño-Mosquera L, Steijns F, Audenaert T, Meerschaut I, De Paepe A, Steyaert W, Symoens S, Coucke P, Callewaert B, Renard M, De Backer J.

Circ Genom Precis Med. 2018 Jun;11(6):e002039. doi: 10.1161/CIRCGEN.117.002039.

PMID:
29875124
10.

Hungarian Marfan family with large FBN1 deletion calls attention to copy number variation detection in the current NGS era.

Benke K, Ágg B, Meienberg J, Kopps AM, Fattorini N, Stengl R, Daradics N, Pólos M, Bors A, Radovits T, Merkely B, De Backer J, Szabolcs Z, Mátyás G.

J Thorac Dis. 2018 Apr;10(4):2456-2460. doi: 10.21037/jtd.2018.04.40.

11.

Looking for the Missing Links: Challenges in the Search for Genotype-Phenotype Correlation in Marfan Syndrome.

De Backer J, Campens L, Muiño Mosquera L.

Circ Genom Precis Med. 2018 Jun;11(6):e002185. doi: 10.1161/CIRCGEN.118.002185. No abstract available.

PMID:
29848616
12.

Influence of Aortic Stiffness on Aortic-Root Growth Rate and Outcome in Patients With the Marfan Syndrome.

Selamet Tierney ES, Levine JC, Sleeper LA, Roman MJ, Bradley TJ, Colan SD, Chen S, Campbell MJ, Cohen MS, De Backer J, Heydarian H, Hoskoppal A, Lai WW, Liou A, Marcus E, Nutting A, Olson AK, Parra DA, Pearson GD, Pierpont ME, Printz BF, Pyeritz RE, Ravekes W, Sharkey AM, Srivastava S, Young L, Lacro RV; Pediatric Heart Network Investigators.

Am J Cardiol. 2018 May 1;121(9):1094-1101. doi: 10.1016/j.amjcard.2018.01.016. Epub 2018 Feb 13.

PMID:
29631804
13.

The Role of Functional Respiratory Imaging in Treatment Selection of Children With Obstructive Sleep Apnea and Down Syndrome.

Slaats MALJ, Loterman D, van Holsbeke C, Vos W, Van Hoorenbeeck K, de Backer J, de Backer W, Wojciechowski M, Boudewyns A, Verhulst S.

J Clin Sleep Med. 2018 Apr 15;14(4):651-659. doi: 10.5664/jcsm.7064.

PMID:
29609707
14.

Changes in ventilation-perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling.

Hajian B, De Backer J, Vos W, van Geffen WH, De Winter P, Usmani O, Cahn T, Kerstjens HA, Pistolesi M, De Backer W.

Int J Chron Obstruct Pulmon Dis. 2018 Mar 6;13:833-842. doi: 10.2147/COPD.S153295. eCollection 2018.

15.
16.

Machine Learning Algorithms Utilizing Quantitative CT Features May Predict Eventual Onset of Bronchiolitis Obliterans Syndrome After Lung Transplantation.

Barbosa EJM Jr, Lanclus M, Vos W, Van Holsbeke C, De Backer W, De Backer J, Lee J.

Acad Radiol. 2018 Sep;25(9):1201-1212. doi: 10.1016/j.acra.2018.01.013. Epub 2018 Feb 19.

PMID:
29472146
17.

Internal State Dependent Odor Processing and Perception-The Role of Neuromodulation in the Fly Olfactory System.

Sayin S, Boehm AC, Kobler JM, De Backer JF, Grunwald Kadow IC.

Front Cell Neurosci. 2018 Jan 30;12:11. doi: 10.3389/fncel.2018.00011. eCollection 2018. Review.

18.

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis.

Logghe G, Trachet B, Aslanidou L, Villaneuva-Perez P, De Backer J, Stergiopulos N, Stampanoni M, Aoki H, Segers P.

Sci Rep. 2018 Feb 2;8(1):2223. doi: 10.1038/s41598-018-20673-x.

19.

Bidirectional Control of Reversal in a Dual Action Task by Direct and Indirect Pathway Activation in the Dorsolateral Striatum in Mice.

Laurent M, De Backer JF, Rial D, Schiffmann SN, de Kerchove d'Exaerde A.

Front Behav Neurosci. 2017 Dec 22;11:256. doi: 10.3389/fnbeh.2017.00256. eCollection 2017.

20.

Arterial tortuosity syndrome: 40 new families and literature review.

Beyens A, Albuisson J, Boel A, Al-Essa M, Al-Manea W, Bonnet D, Bostan O, Boute O, Busa T, Canham N, Cil E, Coucke PJ, Cousin MA, Dasouki M, De Backer J, De Paepe A, De Schepper S, De Silva D, Devriendt K, De Wandele I, Deyle DR, Dietz H, Dupuis-Girod S, Fontenot E, Fischer-Zirnsak B, Gezdirici A, Ghoumid J, Giuliano F, Diéz NB, Haider MZ, Hardin JS, Jeunemaitre X, Klee EW, Kornak U, Landecho MF, Legrand A, Loeys B, Lyonnet S, Michael H, Moceri P, Mohammed S, Muiño-Mosquera L, Nampoothiri S, Pichler K, Prescott K, Rajeb A, Ramos-Arroyo M, Rossi M, Salih M, Seidahmed MZ, Schaefer E, Steichen-Gersdorf E, Temel S, Uysal F, Vanhomwegen M, Van Laer L, Van Maldergem L, Warner D, Willaert A, Collins TR, Taylor A, Davis EC, Zarate Y, Callewaert B.

Genet Med. 2018 Jan 11. doi: 10.1038/gim.2017.253. [Epub ahead of print]

PMID:
29323665
21.

Clinical history and management recommendations of the smooth muscle dysfunction syndrome due to ACTA2 arginine 179 alterations.

Regalado ES, Mellor-Crummey L, De Backer J, Braverman AC, Ades L, Benedict S, Bradley TJ, Brickner ME, Chatfield KC, Child A, Feist C, Holmes KW, Iannucci G, Lorenz B, Mark P, Morisaki T, Morisaki H, Morris SA, Mitchell AL, Ostergaard JR, Richer J, Sallee D, Shalhub S, Tekin M; Montalcino Aortic Consortium, Estrera A, Musolino P, Yetman A, Pyeritz R, Milewicz DM.

Genet Med. 2018 Jan 4. doi: 10.1038/gim.2017.245. [Epub ahead of print]

22.

The role of ethnicity in the upper airway in a Belgian paediatric population with obstructive sleep apnoea.

Slaats M, Vos W, Van Holsbeke C, De Backer J, Loterman D, De Backer W, Boudewyns A, Verhulst S.

Eur Respir J. 2017 Oct 5;50(4). pii: 1701278. doi: 10.1183/13993003.01278-2017. Print 2017 Oct. No abstract available.

PMID:
28982766
23.

Pathophysiological mechanism of long-term noninvasive ventilation in stable hypercapnic patients with COPD using functional respiratory imaging.

Hajian B, De Backer J, Sneyers C, Ferreira F, Barboza KC, Leemans G, Vos W, De Backer W.

Int J Chron Obstruct Pulmon Dis. 2017 Jul 28;12:2197-2205. doi: 10.2147/COPD.S136412. eCollection 2017.

24.

Organisation of care for pregnancy in patients with congenital heart disease.

Roos-Hesselink JW, Budts W, Walker F, De Backer JFA, Swan L, Stones W, Kranke P, Sliwa-Hahnle K, Johnson MR.

Heart. 2017 Dec;103(23):1854-1859. doi: 10.1136/heartjnl-2017-311758. Epub 2017 Jul 24. Review.

PMID:
28739807
25.

Sex, pregnancy and aortic disease in Marfan syndrome.

Renard M, Muiño-Mosquera L, Manalo EC, Tufa S, Carlson EJ, Keene DR, De Backer J, Sakai LY.

PLoS One. 2017 Jul 14;12(7):e0181166. doi: 10.1371/journal.pone.0181166. eCollection 2017. Erratum in: PLoS One. 2018 May 14;13(5):e0197631.

26.

Efficacy of losartan as add-on therapy to prevent aortic growth and ventricular dysfunction in patients with Marfan syndrome: a randomized, double-blind clinical trial.

Muiño-Mosquera L, De Nobele S, Devos D, Campens L, De Paepe A, De Backer J.

Acta Cardiol. 2017 Dec;72(6):616-624. doi: 10.1080/00015385.2017.1314134. Epub 2017 Jun 28.

PMID:
28657492
27.

The spectrum of spontaneous coronary artery dissection: illustrated review of the literature.

Vandamme M, De Backer J, De Backer T, Drieghe B, Devos D, Gevaert S.

Acta Cardiol. 2017 Dec;72(6):599-609. doi: 10.1080/00015385.2017.1309095. Epub 2017 Jun 28.

PMID:
28657457
28.

Image-based computational fluid dynamics in the lung: virtual reality or new clinical practice?

Burrowes KS, De Backer J, Kumar H.

Wiley Interdiscip Rev Syst Biol Med. 2017 Nov;9(6). doi: 10.1002/wsbm.1392. Epub 2017 Jun 13. Review.

PMID:
28608962
29.

Impaired Maintenance of Interpersonal Synchronization in Musical Improvisations of Patients with Borderline Personality Disorder.

Foubert K, Collins T, De Backer J.

Front Psychol. 2017 Apr 27;8:537. doi: 10.3389/fpsyg.2017.00537. eCollection 2017.

30.

The 2017 international classification of the Ehlers-Danlos syndromes.

Malfait F, Francomano C, Byers P, Belmont J, Berglund B, Black J, Bloom L, Bowen JM, Brady AF, Burrows NP, Castori M, Cohen H, Colombi M, Demirdas S, De Backer J, De Paepe A, Fournel-Gigleux S, Frank M, Ghali N, Giunta C, Grahame R, Hakim A, Jeunemaitre X, Johnson D, Juul-Kristensen B, Kapferer-Seebacher I, Kazkaz H, Kosho T, Lavallee ME, Levy H, Mendoza-Londono R, Pepin M, Pope FM, Reinstein E, Robert L, Rohrbach M, Sanders L, Sobey GJ, Van Damme T, Vandersteen A, van Mourik C, Voermans N, Wheeldon N, Zschocke J, Tinkle B.

Am J Med Genet C Semin Med Genet. 2017 Mar;175(1):8-26. doi: 10.1002/ajmg.c.31552.

PMID:
28306229
31.

Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome.

Byers PH, Belmont J, Black J, De Backer J, Frank M, Jeunemaitre X, Johnson D, Pepin M, Robert L, Sanders L, Wheeldon N.

Am J Med Genet C Semin Med Genet. 2017 Mar;175(1):40-47. doi: 10.1002/ajmg.c.31553. Review.

PMID:
28306228
32.

Pregnancy in Women With SMAD3 Mutation.

van Hagen IM, van der Linde D, van de Laar IM, Muiño Mosquera L, De Backer J, Roos-Hesselink JW.

J Am Coll Cardiol. 2017 Mar 14;69(10):1356-1358. doi: 10.1016/j.jacc.2016.12.029. No abstract available.

33.

Predicting the effect of treatment in paediatric OSA by clinical examination and functional respiratory imaging.

Slaats M, Vos W, Van Holsbeke C, De Backer J, Loterman D, De Backer W, Boudewyns A, Verhulst S.

Pediatr Pulmonol. 2017 Jun;52(6):799-805. doi: 10.1002/ppul.23684. Epub 2017 Mar 7.

PMID:
28267299
34.

Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome.

Oller J, Méndez-Barbero N, Ruiz EJ, Villahoz S, Renard M, Canelas LI, Briones AM, Alberca R, Lozano-Vidal N, Hurlé MA, Milewicz D, Evangelista A, Salaices M, Nistal JF, Jiménez-Borreguero LJ, De Backer J, Campanero MR, Redondo JM.

Nat Med. 2017 Feb;23(2):200-212. doi: 10.1038/nm.4266. Epub 2017 Jan 9.

PMID:
28067899
35.

International Registry of Patients Carrying TGFBR1 or TGFBR2 Mutations: Results of the MAC (Montalcino Aortic Consortium).

Jondeau G, Ropers J, Regalado E, Braverman A, Evangelista A, Teixedo G, De Backer J, Muiño-Mosquera L, Naudion S, Zordan C, Morisaki T, Morisaki H, Von Kodolitsch Y, Dupuis-Girod S, Morris SA, Jeremy R, Odent S, Adès LC, Bakshi M, Holman K, LeMaire S, Milleron O, Langeois M, Spentchian M, Aubart M, Boileau C, Pyeritz R, Milewicz DM; Montalcino Aortic Consortium.

Circ Cardiovasc Genet. 2016 Dec;9(6):548-558. doi: 10.1161/CIRCGENETICS.116.001485. Epub 2016 Nov 21.

36.

Long-Term Outcome of Patients with Perimembranous Ventricular Septal Defect: Results from the Belgian Registry on Adult Congenital Heart Disease.

Gabriels C, De Backer J, Pasquet A, Paelinck BP, Morissens M, Helsen F, Van De Bruaene A, Budts W.

Cardiology. 2017;136(3):147-155. doi: 10.1159/000448513. Epub 2016 Sep 21.

37.

Pulmonary vascular effects of pulsed inhaled nitric oxide in COPD patients with pulmonary hypertension.

Hajian B, De Backer J, Vos W, Van Holsbeke C, Ferreira F, Quinn DA, Hufkens A, Claes R, De Backer W.

Int J Chron Obstruct Pulmon Dis. 2016 Jul 5;11:1533-41. doi: 10.2147/COPD.S106480. eCollection 2016.

38.

FBN1: The disease-causing gene for Marfan syndrome and other genetic disorders.

Sakai LY, Keene DR, Renard M, De Backer J.

Gene. 2016 Oct 10;591(1):279-291. doi: 10.1016/j.gene.2016.07.033. Epub 2016 Jul 18. Review.

PMID:
27437668
39.

Efficacy of inhaled medications in asthma and COPD related to disease severity.

Hajian B, De Backer J, Vos W, Aerts J, Cluckers J, De Backer W.

Expert Opin Drug Deliv. 2016 Dec;13(12):1719-1727. Epub 2016 Jun 30. Review.

PMID:
27292454
40.

Assessment of lung deposition and analysis of the effect of fluticasone/salmeterol hydrofluoroalkane (HFA) pressurized metered dose inhaler (pMDI) in stable persistent asthma patients using functional respiratory imaging.

De Backer J, Van Holsbeke C, Vos W, Vinchurkar S, Dorinsky P, Rebello J, Mangale M, Hajian B, De Backer W.

Expert Rev Respir Med. 2016 Aug;10(8):927-33. doi: 10.1080/17476348.2016.1192464. Epub 2016 Jun 1.

PMID:
27227384
41.

Functional respiratory imaging to assess the interaction between systemic roflumilast and inhaled ICS/LABA/LAMA.

Vos W, Hajian B, De Backer J, Van Holsbeke C, Vinchurkar S, Claes R, Hufkens A, Parizel PM, Bedert L, De Backer W.

Int J Chron Obstruct Pulmon Dis. 2016 Feb 4;11:263-71. doi: 10.2147/COPD.S93830. eCollection 2016.

42.

Mitral valve prolapse syndrome and MASS phenotype: Stability of aortic dilatation but progression of mitral valve prolapse.

Rippe M, De Backer J, Kutsche K, Mosquera LM, Schüler H, Rybczynski M, Bernhardt AM, Keyser B, Hillebrand M, Mir TS, Berger J, Blankenberg S, Koschyk D, von Kodolitsch Y.

Int J Cardiol Heart Vasc. 2016 Jan 21;10:39-46. doi: 10.1016/j.ijcha.2016.01.002. eCollection 2016 Mar.

43.

Functional respiratory imaging (FRI) for optimizing therapy development and patient care.

Hajian B, De Backer J, Vos W, Van Holsbeke C, Clukers J, De Backer W.

Expert Rev Respir Med. 2016 Feb;10(2):193-206. doi: 10.1586/17476348.2016.1136216.

PMID:
26731531
44.

[Music therapy and depression].

Van Assche E, De Backer J, Vermote R.

Tijdschr Psychiatr. 2015;57(11):823-9. Dutch.

45.

Clinical utility gene card for: Hereditary thoracic aortic aneurysm and dissection including next-generation sequencing-based approaches.

Arslan-Kirchner M, Arbustini E, Boileau C, Charron P, Child AH, Collod-Beroud G, De Backer J, De Paepe A, Dierking A, Faivre L, Hoffjan S, Jondeau G, Keyser B, Loeys B, Mayer K, Robinson PN, Schmidtke J.

Eur J Hum Genet. 2016 Jan;24(1):e1-5. doi: 10.1038/ejhg.2015.225. Epub 2015 Oct 28. No abstract available.

46.

Type B aortic dissection triggered by heart transplantation in a patient with Marfan syndrome.

Audenaert T, De Pauw M, François K, De Backer J.

BMJ Case Rep. 2015 Oct 16;2015. pii: bcr2015211138. doi: 10.1136/bcr-2015-211138.

47.

Genetic Defects in TAPT1 Disrupt Ciliogenesis and Cause a Complex Lethal Osteochondrodysplasia.

Symoens S, Barnes AM, Gistelinck C, Malfait F, Guillemyn B, Steyaert W, Syx D, D'hondt S, Biervliet M, De Backer J, Witten EP, Leikin S, Makareeva E, Gillessen-Kaesbach G, Huysseune A, Vleminckx K, Willaert A, De Paepe A, Marini JC, Coucke PJ.

Am J Hum Genet. 2015 Oct 1;97(4):521-34. doi: 10.1016/j.ajhg.2015.08.009. Epub 2015 Sep 10.

48.

Comparison of CT-based Lobar Ventilation with 3He MR Imaging Ventilation Measurements.

Tahir BA, Van Holsbeke C, Ireland RH, Swift AJ, Horn FC, Marshall H, Kenworthy JC, Parra-Robles J, Hartley R, Kay R, Brightling CE, De Backer J, Vos W, Wild JM.

Radiology. 2016 Feb;278(2):585-92. doi: 10.1148/radiol.2015142278. Epub 2015 Aug 28.

PMID:
26322908
49.

Cryptosporidium and Giardia in recreational water in Belgium.

Ehsan MA, Casaert S, Levecke B, Van Rooy L, Pelicaen J, Smis A, De Backer J, Vervaeke B, De Smedt S, Schoonbaert F, Lammens S, Warmoes T, Geurden T, Claerebout E.

J Water Health. 2015 Sep;13(3):870-8. doi: 10.2166/wh.2015.268.

PMID:
26322773
50.

Marfan Syndrome and Related Heritable Thoracic Aortic Aneurysms and Dissections.

De Backer J, Renard M, Campens L, Mosquera LM, De Paepe A, Coucke P, Callewaert B, Kodolitsch Yv.

Curr Pharm Des. 2015;21(28):4061-75. Review.

PMID:
26306841

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