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Items: 37

1.

Novel Inhaled Pan-JAK Inhibitor, LAS194046, Reduces Allergen-Induced Airway Inflammation, Late Asthmatic Response, and pSTAT Activation in Brown Norway Rats.

Calbet M, Ramis I, Calama E, Carreño C, Paris S, Maldonado M, Orellana A, Calaf E, Pauta M, De Alba J, Bach J, Miralpeix M.

J Pharmacol Exp Ther. 2019 Aug;370(2):137-147. doi: 10.1124/jpet.119.256263. Epub 2019 May 13.

PMID:
31085698
2.

Pharmacological Profile of AZD8871 (LAS191351), a Novel Inhaled Dual M3 Receptor Antagonist/β 2-Adrenoceptor Agonist Molecule with Long-Lasting Effects and Favorable Safety Profile.

Aparici M, Carcasona C, Ramos I, Montero JL, Otal R, Ortiz JL, Cortijo J, Puig C, Vilella D, De Alba J, Doe C, Gavaldà A, Miralpeix M.

J Pharmacol Exp Ther. 2019 Jul;370(1):127-136. doi: 10.1124/jpet.118.255620. Epub 2019 May 13.

PMID:
31085697
3.

Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS.

Calama E, Ramis I, Domènech A, Carreño C, De Alba J, Prats N, Miralpeix M.

Pulm Pharmacol Ther. 2017 Apr;43:60-67. doi: 10.1016/j.pupt.2017.01.002. Epub 2017 Jan 10.

PMID:
28087469
4.

In vitro and in vivo preclinical profile of abediterol (LAS100977), an inhaled long-acting β2-adrenoceptor agonist, compared with indacaterol, olodaterol and vilanterol.

Aparici M, Gavaldà A, Ramos I, Carcasona C, Otal R, Fernández-Blanco JA, Montero JL, García VM, López R, De Alba J, Doe C, Puig C, Vilella D, Miralpeix M.

Eur J Pharmacol. 2016 Jan 5;770:61-9. doi: 10.1016/j.ejphar.2015.11.053. Epub 2015 Dec 4.

PMID:
26656755
5.

The role of CRAC channel in asthma.

Kaur M, Birrell MA, Dekkak B, Reynolds S, Wong S, De Alba J, Raemdonck K, Hall S, Simpson K, Begg M, Belvisi MG, Singh D.

Pulm Pharmacol Ther. 2015 Dec;35:67-74. doi: 10.1016/j.pupt.2015.09.002. Epub 2015 Sep 4.

6.

Enhanced cough reflex in a model of bleomycin-induced lung fibrosis in guinea pigs.

Fernández-Blanco JA, Aguilera M, Domènech A, Tarrasón G, Prats N, Miralpeix M, De Alba J.

Clin Sci (Lond). 2015 Dec;129(12):1001-10. doi: 10.1042/CS20150302. Epub 2015 Aug 14.

PMID:
26275723
7.

Combined anti CXC receptors 1 and 2 therapy is a promising anti-inflammatory treatment for respiratory diseases by reducing neutrophil migration and activation.

Planagumà A, Domènech T, Pont M, Calama E, García-González V, López R, Aulí M, López M, Fonquerna S, Ramos I, de Alba J, Nueda A, Prats N, Segarra V, Miralpeix M, Lehner MD.

Pulm Pharmacol Ther. 2015 Oct;34:37-45. doi: 10.1016/j.pupt.2015.08.002. Epub 2015 Aug 10. Review.

PMID:
26271598
8.

Double-stranded RNA evokes exacerbation in a mouse model of corticosteroid refractory asthma.

De Alba J, Otal R, Calama E, Domenech A, Prats N, Gozzard N, Miralpeix M; U-BIOPRED consortium.

Clin Sci (Lond). 2015 Dec;129(11):973-87. doi: 10.1042/CS20150292. Epub 2015 Aug 5.

PMID:
26245201
9.

A novel inhaled Syk inhibitor blocks mast cell degranulation and early asthmatic response.

Ramis I, Otal R, Carreño C, Domènech A, Eichhorn P, Orellana A, Maldonado M, De Alba J, Prats N, Fernández JC, Vidal B, Miralpeix M.

Pharmacol Res. 2015 Sep;99:116-24. doi: 10.1016/j.phrs.2015.05.011. Epub 2015 Jun 4.

PMID:
26051661
10.

Discovery of 7-azaindole derivatives as potent Orai inhibitors showing efficacy in a preclinical model of asthma.

Esteve C, González J, Gual S, Vidal L, Alzina S, Sentellas S, Jover I, Horrillo R, De Alba J, Miralpeix M, Tarrasón G, Vidal B.

Bioorg Med Chem Lett. 2015 Mar 15;25(6):1217-22. doi: 10.1016/j.bmcl.2015.01.063. Epub 2015 Feb 4.

PMID:
25690784
11.

Pharmacological characterization of abediterol, a novel inhaled β(2)-adrenoceptor agonist with long duration of action and a favorable safety profile in preclinical models.

Aparici M, Gómez-Angelats M, Vilella D, Otal R, Carcasona C, Viñals M, Ramos I, Gavaldà A, De Alba J, Gras J, Cortijo J, Morcillo E, Puig C, Ryder H, Beleta J, Miralpeix M.

J Pharmacol Exp Ther. 2012 Aug;342(2):497-509. doi: 10.1124/jpet.112.193284. Epub 2012 May 15.

PMID:
22588259
12.

A role for sensory nerves in the late asthmatic response.

Raemdonck K, de Alba J, Birrell MA, Grace M, Maher SA, Irvin CG, Fozard JR, O'Byrne PM, Belvisi MG.

Thorax. 2012 Jan;67(1):19-25. doi: 10.1136/thoraxjnl-2011-200365. Epub 2011 Aug 13.

PMID:
21841185
13.

[Classifying Mexican adolescents' high blood pressure, associated factors and importance].

Salcedo-Rocha AL, de Alba JE, Contreras-Marmolejo M.

Rev Salud Publica (Bogota). 2010 Aug;12(4):612-22. Spanish.

14.

House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?

De Alba J, Raemdonck K, Dekkak A, Collins M, Wong S, Nials AT, Knowles RG, Belvisi MG, Birrell MA.

Eur Respir J. 2010 Jun;35(6):1377-87. doi: 10.1183/09031936.00022908. Epub 2009 Oct 19.

15.

Inferring genetic parameters of lactation in Tropical Milking Criollo cattle with random regression test-day models.

Santellano-Estrada E, Becerril-Pérez CM, de Alba J, Chang YM, Gianola D, Torres-Hernández G, Ramírez-Valverde R.

J Dairy Sci. 2008 Nov;91(11):4393-400. doi: 10.3168/jds.2007-0351.

16.

Liver X receptor agonists increase airway reactivity in a model of asthma via increasing airway smooth muscle growth.

Birrell MA, De Alba J, Catley MC, Hardaker E, Wong S, Collins M, Clarke DL, Farrow SN, Willson TM, Collins JL, Belvisi MG.

J Immunol. 2008 Sep 15;181(6):4265-71.

17.

Estrogen receptor beta: expression profile and possible anti-inflammatory role in disease.

Catley MC, Birrell MA, Hardaker EL, de Alba J, Farrow S, Haj-Yahia S, Belvisi MG.

J Pharmacol Exp Ther. 2008 Jul;326(1):83-8. doi: 10.1124/jpet.108.136275. Epub 2008 Mar 28.

PMID:
18375789
18.

Time reproduction disturbances in ADHD children: an ERP study.

González-Garrido AA, Gómez-Velázquez FR, Zarabozo D, López-Elizalde R, Ontiveros A, Madera-Carrillo H, Vega OL, De Alba JL, Tuya JM.

Int J Neurosci. 2008 Jan;118(1):119-35.

PMID:
18041610
19.

Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.

Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG.

J Pharmacol Exp Ther. 2006 Aug;318(2):741-50. Epub 2006 May 11.

PMID:
16690722
20.

GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain.

De Alba J, Clayton NM, Collins SD, Colthup P, Chessell I, Knowles RG.

Pain. 2006 Jan;120(1-2):170-81. Epub 2005 Dec 19.

PMID:
16360270
21.

An animal model of chronic inflammatory pain: pharmacological and temporal differentiation from acute models.

Wilson AW, Medhurst SJ, Dixon CI, Bontoft NC, Winyard LA, Brackenborough KT, De Alba J, Clarke CJ, Gunthorpe MJ, Hicks GA, Bountra C, McQueen DS, Chessell IP.

Eur J Pain. 2006 Aug;10(6):537-49. Epub 2005 Sep 30.

PMID:
16199187
22.

Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma.

Birrell MA, Hardaker E, Wong S, McCluskie K, Catley M, De Alba J, Newton R, Haj-Yahia S, Pun KT, Watts CJ, Shaw RJ, Savage TJ, Belvisi MG.

Am J Respir Crit Care Med. 2005 Oct 15;172(8):962-71. Epub 2005 Jul 7.

PMID:
16002568
23.

Inducible nitric oxide synthase is involved in the mechanisms of cocaine enhanced neuronal apoptosis induced by HIV-1 gp120 in the neocortex of rat.

Bagetta G, Piccirilli S, Del Duca C, Morrone LA, Rombolà L, Nappi G, De Alba J, Knowles RG, Corasaniti MT.

Neurosci Lett. 2004 Feb 19;356(3):183-6.

PMID:
15036625
24.

Hypercalculia in savant syndrome: central executive failure?

González-Garrido AA, Ruiz-Sandoval JL, Gómez-Velázquez FR, de Alba JL, Villaseñor-Cabrera T.

Arch Med Res. 2002 Nov-Dec;33(6):586-9.

PMID:
12505107
25.

Event-related brain potentials during a continuous performance test (CPT) task in normal children.

González-Garrido AA, Gómez-Velázquez FR, Fernández-Harmony T, de Alba JL, Ruiz-Sandoval JL.

Arch Med Res. 2001 May-Jun;32(3):214-20.

PMID:
11395187
26.

Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices.

Moro MA, De Alba J, Cárdenas A, De Cristóbal J, Leza JC, Lizasoain I, Díaz-Guerra MJ, Boscá L, Lorenzo P.

Neuropharmacology. 2000 Apr 27;39(7):1309-18.

PMID:
10760373
27.

Use of brain slices in the study of pathogenic role of inducible nitric oxide synthase in cerebral ischemia-reperfusion.

De Alba J, Cárdenas A, Moro MA, Leza JC, Lorenzo P, Lizasoain I.

Gen Pharmacol. 1999 May;32(5):577-81.

PMID:
10382860
28.

Down-regulation of neuronal nitric oxide synthase by nitric oxide after oxygen-glucose deprivation in rat forebrain slices.

De Alba J, Cárdenas A, Moro MA, Leza JC, Lorenzo P, Boscá L, Lizasoain I.

J Neurochem. 1999 Jan;72(1):248-54.

29.

Protective effect of N-(3-(aminomethyl)benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation.

Cárdenas A, De Alba J, Moro MA, Leza JC, Lorenzo P, Lizasoain I.

Eur J Pharmacol. 1998 Aug 7;354(2-3):161-5.

PMID:
9754916
30.

Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices.

Moro MA, De Alba J, Leza JC, Lorenzo P, Fernández AP, Bentura ML, Boscá L, Rodrigo J, Lizasoain I.

Eur J Neurosci. 1998 Feb;10(2):445-56.

PMID:
9749707
31.

[Prosthetic endocarditis and splenic abscess caused by Clostridium clostridiformis].

Robles P, García-Gallego F, de Alba J, García J, Domínguez FJ, Oliver JM.

Rev Esp Cardiol. 1997 May;50(5):360-2. Spanish.

32.

[Aortic prosthetic endocarditis and periprosthetic abscess caused by Staphylococcus aureus].

García García JM, Maté I, de Alba JM, Robles P, Gómez JA, Domínguez F, Oliver J, Mesa JM, Sobrino JA.

Rev Esp Cardiol. 1995 Jul;48(7):496-8. Spanish.

PMID:
7638414
33.

Changes induced by sodium cromoglycate in brain catecholamine turnover in morphine dependent and abstinent mice.

San-Martín-Clark O, Cuéllar B, De Alba J, Leza JC, Lorenzo P.

Psychopharmacology (Berl). 1995 Apr;118(3):347-53.

PMID:
7617828
34.

Endocrinology of the postpartum period in the Pelibuey ewe.

Gonzalez A, Murphy BD, de Alba J, Manns JG.

J Anim Sci. 1987 Jun;64(6):1717-24.

PMID:
3597187
35.

Experimental force analysis of the contraction utility arch wire.

Murphy NC, de Alba JA, Chaconas SJ, Caputo AA.

Am J Orthod. 1982 Nov;82(5):411-7.

PMID:
6961811
36.

Canine retraction with J hook headgear.

Ayala Perez C, de Alba JA, Caputo AA, Chaconas SJ.

Am J Orthod. 1980 Nov;78(5):538-47.

PMID:
6933859
37.

Estrous behavior and hormones in the cow.

DE ALBA J, ASDELL SA.

J Comp Psychol. 1946 Apr;39:119-23. No abstract available.

PMID:
21023311

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