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Items: 8


Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence.

Choy CH, Saffi G, Gray MA, Wallace C, Dayam RM, Ou ZA, Lenk G, Puertollano R, Watkins SC, Botelho RJ.

J Cell Sci. 2018 May 21;131(10). pii: jcs213587. doi: 10.1242/jcs.213587.


Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium.

Delos Santos RC, Bautista S, Lucarelli S, Bone LN, Dayam RM, Abousawan J, Botelho RJ, Antonescu CN.

Mol Biol Cell. 2017 Oct 15;28(21):2802-2818. doi: 10.1091/mbc.E16-12-0871. Epub 2017 Aug 16.


The Lipid Kinase PIKfyve Coordinates the Neutrophil Immune Response through the Activation of the Rac GTPase.

Dayam RM, Sun CX, Choy CH, Mancuso G, Glogauer M, Botelho RJ.

J Immunol. 2017 Sep 15;199(6):2096-2105. doi: 10.4049/jimmunol.1601466. Epub 2017 Aug 4.


The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic.

Bone LN, Dayam RM, Lee M, Kono N, Fairn GD, Arai H, Botelho RJ, Antonescu CN.

Mol Biol Cell. 2017 Jan 1;28(1):161-172. doi: 10.1091/mbc.E16-09-0668. Epub 2016 Nov 9.


Quantitative Immunofluorescence to Study Phagosome Maturation.

Dayam RM, Botelho RJ.

Methods Mol Biol. 2017;1519:113-123.


Phagocytosis Enhances Lysosomal and Bactericidal Properties by Activating the Transcription Factor TFEB.

Gray MA, Choy CH, Dayam RM, Ospina-Escobar E, Somerville A, Xiao X, Ferguson SM, Botelho RJ.

Curr Biol. 2016 Aug 8;26(15):1955-1964. doi: 10.1016/j.cub.2016.05.070. Epub 2016 Jul 7.


The Phosphoinositide-Gated Lysosomal Ca(2+) Channel, TRPML1, Is Required for Phagosome Maturation.

Dayam RM, Saric A, Shilliday RE, Botelho RJ.

Traffic. 2015 Sep;16(9):1010-26. doi: 10.1111/tra.12303. Epub 2015 Jun 18.


PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages.

Kim GH, Dayam RM, Prashar A, Terebiznik M, Botelho RJ.

Traffic. 2014 Oct;15(10):1143-63. doi: 10.1111/tra.12199. Epub 2014 Aug 16.

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