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Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial.

Masse MH, Ménard J, Sprague S, Battista MC, Cook DJ, Guyatt GH, Heyland DK, Kanji S, Pinto R, Day AG, Cohen D, Annane D, McGuinness S, Parke R, Carr A, Arabi Y, Vijayaraghavan BKT, D'Aragon F, Carbonneau É, Maslove D, Hunt M, Rochwerg B, Millen T, Chassé M, Lebrasseur M, Archambault P, Deblois E, Drouin C, Lellouche F, Lizotte P, Watpool I, Porteous R, Clarke F, Marinoff N, Belley-Côté É, Bolduc B, Walker S, Iazzetta J, Adhikari NKJ, Lamontagne F; Canadian Critical Care Trials Group.

Trials. 2020 Jan 8;21(1):42. doi: 10.1186/s13063-019-3834-1.


Promotion of Regular Oesophageal Motility to Prevent Regurgitation and Enhance Nutrition Intake in Long-Stay ICU Patients. A Multicenter, Phase II, Sham-Controlled, Randomized Trial: The PROPEL Study.

Heyland DK, Marquis F, Lamontagne F, Albert M, Turgeon AF, Khwaja KA, Garland A, Hall R, Chapman MG, Kutsiogannis DJ, Martin C, Sessler DI, Day AG.

Crit Care Med. 2020 Jan 6. doi: 10.1097/CCM.0000000000004176. [Epub ahead of print]


Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery.

Galvin IM, Levy R, Day AG, Gilron I.

Cochrane Database Syst Rev. 2019 Nov 21;2019(11). doi: 10.1002/14651858.CD011931.pub2. Review.


Impact of a Specialized Ambulatory Clinic on Refractory Breathlessness in Subjects With Advanced COPD: A Retrospective Analysis.

Elbehairy AF, McIsaac H, Hill E, Norman PA, Day AG, Neder JA, O'Donnell DE, Harle IA.

Respir Care. 2019 Nov 12. pii: respcare.06950. doi: 10.4187/respcare.06950. [Epub ahead of print]


Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease.

Ravell JC, Matsuda-Lennikov M, Chauvin SD, Zou J, Biancalana M, Deeb SJ, Price S, Su HC, Notarangelo G, Jiang P, Morawski A, Kanellopoulou C, Binder K, Mukherjee R, Anibal JT, Sellers B, Zheng L, He T, George AB, Pittaluga S, Powers A, Kleiner DE, Kapuria D, Ghany M, Hunsberger S, Cohen JI, Uzel G, Bergerson J, Wolfe L, Toro C, Gahl W, Folio LR, Matthews H, Angelus P, Chinn IK, Orange JS, Trujillo-Vargas CM, Franco JL, Orrego-Arango J, Gutiérrez-Hincapié S, Patel NC, Raymond K, Patiroglu T, Unal E, Karakukcu M, Day AG, Mehta P, Masutani E, De Ravin SS, Malech HL, Altan-Bonnet G, Rao VK, Mann M, Lenardo MJ.

J Clin Invest. 2020 Jan 2;130(1):507-522. doi: 10.1172/JCI131116.


Individual Response to Standardized Exercise: Total and Abdominal Adipose Tissue.

Brennan AM, Day AG, Cowan TE, Clarke GJ, Lamarche B, Ross R.

Med Sci Sports Exerc. 2020 Feb;52(2):490-497. doi: 10.1249/MSS.0000000000002140.


A high-bias, low-variance introduction to Machine Learning for physicists.

Mehta P, Wang CH, Day AGR, Richardson C, Bukov M, Fisher CK, Schwab DJ.

Phys Rep. 2019 May 30;810:1-124. doi: 10.1016/j.physrep.2019.03.001. Epub 2019 Mar 14.


Precision exercise medicine: understanding exercise response variability.

Ross R, Goodpaster BH, Koch LG, Sarzynski MA, Kohrt WM, Johannsen NM, Skinner JS, Castro A, Irving BA, Noland RC, Sparks LM, Spielmann G, Day AG, Pitsch W, Hopkins WG, Bouchard C.

Br J Sports Med. 2019 Sep;53(18):1141-1153. doi: 10.1136/bjsports-2018-100328. Epub 2019 Mar 12.


Individual Response to Standardized Exercise: Total and Abdominal Adipose Tissue.

Brennan AM, Day AG, Cowan TE, Clarke GJ, Lamarche B, Ross R.

Med Sci Sports Exerc. 2019 Feb 15. doi: 10.1249/MSS.0000000000001930. [Epub ahead of print]


Glassy Phase of Optimal Quantum Control.

Day AGR, Bukov M, Weinberg P, Mehta P, Sels D.

Phys Rev Lett. 2019 Jan 18;122(2):020601. doi: 10.1103/PhysRevLett.122.020601.


A Patient-Centered Mobile Health System That Supports Asthma Self-Management (breathe): Design, Development, and Utilization.

Morita PP, Yeung MS, Ferrone M, Taite AK, Madeley C, Stevens Lavigne A, To T, Lougheed MD, Gupta S, Day AG, Cafazzo JA, Licskai C.

JMIR Mhealth Uhealth. 2019 Jan 28;7(1):e10956. doi: 10.2196/10956.


Adaptation and Preliminary Validation of the Advance Care Planning Engagement Survey for Surrogate Decision Makers.

Van Scoy LJ, Day AG, Howard M, Sudore R, Heyland DK.

J Pain Symptom Manage. 2019 May;57(5):980-988.e9. doi: 10.1016/j.jpainsymman.2019.01.008. Epub 2019 Jan 24.


Intravital imaging reveals systemic ezrin inhibition impedes cancer cell migration and lymph node metastasis in breast cancer.

Ghaffari A, Hoskin V, Turashvili G, Varma S, Mewburn J, Mullins G, Greer PA, Kiefer F, Day AG, Madarnas Y, SenGupta S, Elliott BE.

Breast Cancer Res. 2019 Jan 24;21(1):12. doi: 10.1186/s13058-018-1079-7.


Are all low-NUTRIC-score patients the same? Analysis of a multi-center observational study to determine the relationship between nutrition intake and outcome.

Chourdakis M, Grammatikopoulou MG, Day AG, Bouras E, Heyland DK.

Clin Nutr. 2019 Dec;38(6):2783-2789. doi: 10.1016/j.clnu.2018.12.006. Epub 2018 Dec 8.


Mediation Analysis of High Blood Pressure Targets, Arrhythmias, and Shock Mortality.

Walkey AJ, Adhikari NKJ, Day AG, Radermacher P, Asfar P, Lamontagne F.

Am J Respir Crit Care Med. 2019 Mar 15;199(6):802-805. doi: 10.1164/rccm.201808-1435LE. No abstract available.


Handheld versus conventional vascular ultrasound for assessing carotid artery plaque.

Mantella LE, Colledanchise K, Bullen M, Hétu MF, Day AG, McLellan CS, Johri AM.

Int J Cardiol. 2019 Mar 1;278:295-299. doi: 10.1016/j.ijcard.2018.12.014. Epub 2018 Dec 5.


Comparison of the new and traditional CKD-EPI GFR estimation equations with urinary inulin clearance: A study of equation performance.

White CA, Allen CM, Akbari A, Collier CP, Holland DC, Day AG, Knoll GA.

Clin Chim Acta. 2019 Jan;488:189-195. doi: 10.1016/j.cca.2018.11.019. Epub 2018 Nov 13.


Is recovery from ankle sprains negatively affected by obesity?

Bielska IA, Brison R, Brouwer B, Janssen I, Johnson AP, Day AG, Pickett W.

Ann Phys Rehabil Med. 2019 Jan;62(1):8-13. doi: 10.1016/ Epub 2018 Oct 2.


Osteogenic Potential of Human Umbilical Cord Mesenchymal Stem Cells on Coralline Hydroxyapatite/Calcium Carbonate Microparticles.

Day AGE, Francis WR, Fu K, Pieper IL, Guy O, Xia Z.

Stem Cells Int. 2018 Sep 5;2018:4258613. doi: 10.1155/2018/4258613. eCollection 2018.


Individual Variability in Waist Circumference and Body Weight in Response to Exercise.

Hammond BP, Stotz PJ, Brennan AM, Lamarche B, Day AG, Ross R.

Med Sci Sports Exerc. 2019 Feb;51(2):315-322. doi: 10.1249/MSS.0000000000001784.


Speckle tracking carotid artery circumferential strain is a marker of arterial sclerosis but not coronary atherosis.

Patton DM, Li T, Hétu MF, Day AG, Preece E, Matangi MF, Johri AM.

J Clin Ultrasound. 2018 Nov;46(9):575-581. doi: 10.1002/jcu.22632. Epub 2018 Aug 13.


Interpregnancy Intervals in a Contemporary Manitoba Cohort: Prevalence of So-Called Suboptimal Intervals and Associated Maternal Characteristics.

Coo H, Brownell MD, Ruth C, Flavin M, Au W, Day AG.

J Obstet Gynaecol Can. 2018 Aug;40(8):1024-1030. doi: 10.1016/j.jogc.2017.12.001.


Prevention of Nosocomial Infections in Critically Ill Patients With Lactoferrin: A Randomized, Double-Blind, Placebo-Controlled Study.

Muscedere J, Maslove DM, Boyd JG, O'Callaghan N, Sibley S, Reynolds S, Albert M, Hall R, Jiang X, Day AG, Jones G, Lamontagne F.

Crit Care Med. 2018 Sep;46(9):1450-1456. doi: 10.1097/CCM.0000000000003294.


Nutrition Adequacy Therapeutic Enhancement in the Critically Ill: A Randomized Double-Blind, Placebo-Controlled Trial of the Motilin Receptor Agonist Camicinal (GSK962040): The NUTRIATE Study.

Deane AM, Lamontagne F, Dukes GE, Neil D, Vasist L, Barton ME, Hacquoil K, Ou X, Richards D, Stelfox HT, Mehta S, Day AG, Chapman MJ, Heyland DK.

JPEN J Parenter Enteral Nutr. 2018 Jul;42(5):949-959. doi: 10.1002/jpen.1038. Epub 2017 Dec 28.


A RandomizEd trial of ENtERal Glutamine to minimIZE thermal injury (The RE-ENERGIZE Trial): a clinical trial protocol.

Heyland DK, Wischmeyer P, Jeschke MG, Wibbenmeyer L, Turgeon AF, Stelfox HT, Day AG, Garrel D.

Scars Burn Heal. 2017 Dec 12;3:2059513117745241. doi: 10.1177/2059513117745241. eCollection 2017 Jan-Dec.


Investigating Cortisol Production and Pattern as Mediators in the Relationship Between Shift Work and Cardiometabolic Risk.

Ritonja J, Aronson KJ, Day AG, Korsiak J, Tranmer J.

Can J Cardiol. 2018 May;34(5):683-689. doi: 10.1016/j.cjca.2018.02.006. Epub 2018 Feb 9.


Calorie intake and short-term survival of critically ill patients.

Hartl WH, Bender A, Scheipl F, Kuppinger D, Day AG, Küchenhoff H.

Clin Nutr. 2019 Apr;38(2):660-667. doi: 10.1016/j.clnu.2018.04.005. Epub 2018 Apr 18.


An Optimized Collagen-Fibrin Blend Engineered Neural Tissue Promotes Peripheral Nerve Repair.

Schuh CMAP, Day AGE, Redl H, Phillips J.

Tissue Eng Part A. 2018 Sep;24(17-18):1332-1340. doi: 10.1089/ten.TEA.2017.0457. Epub 2018 Jun 13.


Penalized estimation of complex, non-linear exposure-lag-response associations.

Bender A, Scheipl F, Hartl W, Day AG, Küchenhoff H.

Biostatistics. 2019 Apr 1;20(2):315-331. doi: 10.1093/biostatistics/kxy003.


An allogeneic 'off the shelf' therapeutic strategy for peripheral nerve tissue engineering using clinical grade human neural stem cells.

O'Rourke C, Day AGE, Murray-Dunning C, Thanabalasundaram L, Cowan J, Stevanato L, Grace N, Cameron G, Drake RAL, Sinden J, Phillips JB.

Sci Rep. 2018 Feb 13;8(1):2951. doi: 10.1038/s41598-018-20927-8.


Lack of effect of Timothy grass pollen sublingual immunotherapy tablet on birch pollen-induced allergic rhinoconjunctivitis in an environmental exposure unit.

Ellis AK, Tenn MW, Steacy LM, Adams DE, Day AG, Walker TJ, Nolte H.

Ann Allergy Asthma Immunol. 2018 May;120(5):495-503.e2. doi: 10.1016/j.anai.2018.02.003. Epub 2018 Feb 9.


Improving partnerships with family members of ICU patients: study protocol for a randomized controlled trial.

Heyland DK, Davidson J, Skrobik Y, des Ordons AR, Van Scoy LJ, Day AG, Vandall-Walker V, Marshall AP.

Trials. 2018 Jan 4;19(1):3. doi: 10.1186/s13063-017-2379-4.


Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.

Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, Radermacher P, Chrétien JM, Beaudoin N, Hébert P, D'Aragon F, Meziani F, Asfar P.

Intensive Care Med. 2018 Jan;44(1):12-21. doi: 10.1007/s00134-017-5016-5. Epub 2017 Dec 19.


Abundant expression of BMI1 in follicular lymphoma is associated with reduced overall survival.

AlJohani N, Choi SJ, Day AG, Alhejaily A, Virk S, Baetz T, LeBrun DP.

Leuk Lymphoma. 2018 Sep;59(9):2211-2219. doi: 10.1080/10428194.2017.1410883. Epub 2017 Dec 18.


The Effect of Hypothermic and Cryogenic Preservation on Engineered Neural Tissue.

Day AGE, Bhangra KS, Murray-Dunning C, Stevanato L, Phillips JB.

Tissue Eng Part C Methods. 2017 Oct;23(10):575-582. doi: 10.1089/ten.TEC.2017.0244.


Discordance between patients' stated values and treatment preferences for end-of-life care: results of a multicentre survey.

Heyland DK, Heyland R, Dodek P, You JJ, Sinuff T, Hiebert T, Jiang X, Day AG; ACCEPT Study Team and the Canadian Researchers at the End of Life Network (CARENET).

BMJ Support Palliat Care. 2017 Sep;7(3):292-299. doi: 10.1136/bmjspcare-2015-001056. Epub 2016 Oct 6.


Development and Psychometric Properties of a Survey to Assess Barriers to Implementing Advance Care Planning in Primary Care.

Howard M, Day AG, Bernard C, Tan A, You J, Klein D, Heyland DK.

J Pain Symptom Manage. 2018 Jan;55(1):12-21. doi: 10.1016/j.jpainsymman.2017.08.003. Epub 2017 Aug 10.


Interpregnancy Interval and Congenital Anomalies: A Record-Linkage Study Using the Manitoba Population Research Data Repository.

Coo H, Brownell MD, Ruth C, Flavin M, Au W, Day AG.

J Obstet Gynaecol Can. 2017 Nov;39(11):996-1007. doi: 10.1016/j.jogc.2017.04.039. Epub 2017 Jul 28.


Patient-family agreement on values and preferences for life-sustaining treatment: results of a multicentre observational study.

Abdul-Razzak A, Heyland DK, Simon J, Ghosh S, Day AG, You JJ.

BMJ Support Palliat Care. 2019 Mar;9(1):e20. doi: 10.1136/bmjspcare-2016-001284. Epub 2017 Jul 22.


Protocol adherence for continuously titrated interventions in randomized trials: an overview of the current methodology and case study.

Lauzier F, Adhikari NK, Seely A, Koo KKY, Belley-Côté EP, Burns KEA, Cook DJ, D'Aragon F, Rochwerg B, Kho ME, Oczkowksi SJW, Duan EH, Meade MO, Day AG, Lamontagne F; for ACCADEMY (Academy of Critical Care – Development, Evaluation, and Methodology).

BMC Med Res Methodol. 2017 Jul 17;17(1):106. doi: 10.1186/s12874-017-0388-3.


Low brain tissue oxygenation contributes to the development of delirium in critically ill patients: A prospective observational study.

Cerebral Oxygenation and Neurological Outcomes Following Critical Illness (CONFOCAL) Research Group; Canadian Critical Care Trials Group, Wood MD, Maslove DM, Muscedere JG, Day AG, Gordon Boyd J.

J Crit Care. 2017 Oct;41:289-295. doi: 10.1016/j.jcrc.2017.06.009. Epub 2017 Jun 15.


Barriers to Goals of Care Discussions With Patients Who Have Advanced Heart Failure: Results of a Multicenter Survey of Hospital-Based Cardiology Clinicians.

You JJ, Aleksova N, Ducharme A, MacIver J, Mielniczuk L, Fowler RA, Demers C, Clarke B, Parent MC, Toma M, Strachan PH, Farand P, Isaac D, Zieroth S, Swinton M, Jiang X, Day AG, Heyland DK, Ross HJ.

J Card Fail. 2017 Nov;23(11):786-793. doi: 10.1016/j.cardfail.2017.06.003. Epub 2017 Jun 23.


A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial.

Wischmeyer PE, Hasselmann M, Kummerlen C, Kozar R, Kutsogiannis DJ, Karvellas CJ, Besecker B, Evans DK, Preiser JC, Gramlich L, Jeejeebhoy K, Dhaliwal R, Jiang X, Day AG, Heyland DK.

Crit Care. 2017 Jun 9;21(1):142. doi: 10.1186/s13054-017-1736-8.


Vasopressor use following traumatic injury - A single center retrospective study.

Hylands M, Godbout MP, Mayer SK, Fraser WD, Vanasse A, Leclair MA, Turgeon AF, Lauzier F, Charbonney E, Trottier V, Razek TS, Roy A, D'Aragon F, Belley-Côté E, Day AG, Le Guillan S, Sabbagh R, Lamontagne F.

PLoS One. 2017 Apr 27;12(4):e0176587. doi: 10.1371/journal.pone.0176587. eCollection 2017.


Total Spinal Anesthesia Failure: Have You Assessed the Sensory Anesthesia in Sacral Dermatomes?

de Sá Oliveira RR, Módolo MP, Mizubuti GB, Ho AMH, de Barros GAM, Muniz da Silva L, Braz LG, Módolo NSP, Day AG, Phelan R, Navarro E Lima LH, Ganem EM.

Anesth Analg. 2017 May;124(5):1674-1677. doi: 10.1213/ANE.0000000000001966.


Family physician-led, team-based, lifestyle intervention in patients with metabolic syndrome: results of a multicentre feasibility project.

Jeejeebhoy K, Dhaliwal R, Heyland DK, Leung R, Day AG, Brauer P, Royall D, Tremblay A, Mutch DM, Pliamm L, Rhéaume C, Klein D.

CMAJ Open. 2017 Mar 14;5(1):E229-E236. doi: 10.9778/cmajo.20160101. eCollection 2017 Jan-Mar. Erratum in: CMAJ Open. 2017 May 1;5(2):E337.


Interpregnancy Interval and Adverse Perinatal Outcomes: A Record-Linkage Study Using the Manitoba Population Research Data Repository.

Coo H, Brownell MD, Ruth C, Flavin M, Au W, Day AG.

J Obstet Gynaecol Can. 2017 Jun;39(6):420-433. doi: 10.1016/j.jogc.2017.01.010. Epub 2017 Mar 28.


Sham acupuncture is as efficacious as true acupuncture for the treatment of IBS: A randomized placebo controlled trial.

Lowe C, Aiken A, Day AG, Depew W, Vanner SJ.

Neurogastroenterol Motil. 2017 Jul;29(7). doi: 10.1111/nmo.13040. Epub 2017 Mar 2.



Hookey L, Louw J, Wiepjes M, Rubinger N, Van Weyenberg S, Day AG, Paterson W.

Gastrointest Endosc. 2017 Mar;85(3):684-685. doi: 10.1016/j.gie.2016.10.016. No abstract available.


Vasopressor Use for Severe Hypotension-A Multicentre Prospective Observational Study.

Lamontagne F, Cook DJ, Meade MO, Seely A, Day AG, Charbonney E, Serri K, Skrobik Y, Hebert P, St-Arnaud C, Quiroz-Martinez H, Mayette M, Heyland DK.

PLoS One. 2017 Jan 20;12(1):e0167840. doi: 10.1371/journal.pone.0167840. eCollection 2017.

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