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Items: 1 to 50 of 194

1.

Efficient Assembly of Quantum Dots with Homogenous Glycans Derived from Natural N-Linked Glycoproteins.

Palomo V, Cistrone PA, Zhan N, Palui G, Mattoussi H, Dawson PE.

Bioconjug Chem. 2018 Sep 19;29(9):3144-3153. doi: 10.1021/acs.bioconjchem.8b00477. Epub 2018 Aug 20.

PMID:
30063825
2.

Leveraging the Knorr Pyrazole Synthesis for the Facile Generation of Thioester Surrogates for use in Native Chemical Ligation.

Flood DT, Hintzen JCJ, Bird MJ, Cistrone PA, Chen JS, Dawson PE.

Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11634-11639. doi: 10.1002/anie.201805191. Epub 2018 Aug 10.

PMID:
29908104
3.

Post-Translational Backbone Engineering through Selenomethionine-Mediated Incorporation of Freidinger Lactams.

Flood DT, Yan NL, Dawson PE.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8697-8701. doi: 10.1002/anie.201804885. Epub 2018 Jun 11.

PMID:
29797386
4.

Expedient on-resin synthesis of peptidic benzimidazoles.

Bird MJ, Silvestri AP, Dawson PE.

Bioorg Med Chem Lett. 2018 Sep 1;28(16):2679-2681. doi: 10.1016/j.bmcl.2018.04.062. Epub 2018 May 3.

PMID:
29739642
5.

Site-Specific Three-Color Labeling of α-Synuclein via Conjugation to Uniquely Reactive Cysteines during Assembly by Native Chemical Ligation.

Lee TC, Moran CR, Cistrone PA, Dawson PE, Deniz AA.

Cell Chem Biol. 2018 Jun 21;25(6):797-801.e4. doi: 10.1016/j.chembiol.2018.03.009. Epub 2018 Apr 19.

PMID:
29681525
6.

Rigid Peptide Macrocycles from On-Resin Glaser Stapling.

Cistrone PA, Silvestri AP, Hintzen JCJ, Dawson PE.

Chembiochem. 2018 May 18;19(10):1031-1035. doi: 10.1002/cbic.201800121. Epub 2018 Apr 26.

PMID:
29516601
7.

Borylated oximes: versatile building blocks for organic synthesis.

Liew SK, Holownia A, Diaz DB, Cistrone PA, Dawson PE, Yudin AK.

Chem Commun (Camb). 2017 Oct 18;53(81):11237-11240. doi: 10.1039/c7cc06579e. Epub 2017 Sep 29.

8.

Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery.

Breger JC, Muttenthaler M, Delehanty JB, Thompson DA, Oh E, Susumu K, Deschamps JR, Anderson GP, Field LD, Walper SA, Dawson PE, Medintz IL.

Nanoscale. 2017 Jul 27;9(29):10447-10464. doi: 10.1039/c7nr03362a.

PMID:
28703833
9.

Adapting the Glaser Reaction for Bioconjugation: Robust Access to Structurally Simple, Rigid Linkers.

Silvestri AP, Cistrone PA, Dawson PE.

Angew Chem Int Ed Engl. 2017 Aug 21;56(35):10438-10442. doi: 10.1002/anie.201705065. Epub 2017 Jul 21.

10.

Base-catalyzed diastereoselective trimerization of trifluoroacetone.

Silvestri AP, Dawson PE.

Org Biomol Chem. 2017 Jun 28;15(24):5131-5134. doi: 10.1039/c7ob01094j. Epub 2017 Jun 8.

11.

Conformational Heterogeneity and DNA Recognition by the Morphogen Bicoid.

Adhikary R, Tan YX, Liu J, Zimmermann J, Holcomb M, Yvellez C, Dawson PE, Romesberg FE.

Biochemistry. 2017 Jun 6;56(22):2787-2793. doi: 10.1021/acs.biochem.7b00255. Epub 2017 May 26.

PMID:
28547993
12.

Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential.

Nag OK, Stewart MH, Deschamps JR, Susumu K, Oh E, Tsytsarev V, Tang Q, Efros AL, Vaxenburg R, Black BJ, Chen Y, O'Shaughnessy TJ, North SH, Field LD, Dawson PE, Pancrazio JJ, Medintz IL, Chen Y, Erzurumlu RS, Huston AL, Delehanty JB.

ACS Nano. 2017 Jun 27;11(6):5598-5613. doi: 10.1021/acsnano.7b00954. Epub 2017 May 30.

13.

Chemoproteomic profiling and discovery of protein electrophiles in human cells.

Matthews ML, He L, Horning BD, Olson EJ, Correia BE, Yates JR 3rd, Dawson PE, Cravatt BF.

Nat Chem. 2017 Mar;9(3):234-243. doi: 10.1038/nchem.2645. Epub 2016 Oct 31.

14.

Concurrent Modulation of Quantum Dot Photoluminescence Using a Combination of Charge Transfer and Förster Resonance Energy Transfer: Competitive Quenching and Multiplexed Biosensing Modality.

Algar WR, Khachatrian A, Melinger JS, Huston AL, Stewart MH, Susumu K, Blanco-Canosa JB, Oh E, Dawson PE, Medintz IL.

J Am Chem Soc. 2017 Jan 11;139(1):363-372. doi: 10.1021/jacs.6b11042. Epub 2016 Dec 23.

15.

Modifications of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor To Achieve High Plasma Stability.

Olson EJ, Lechtenberg BC, Zhao C, Rubio de la Torre E, Lamberto I, Riedl SJ, Dawson PE, Pasquale EB.

ACS Med Chem Lett. 2016 Jun 25;7(9):841-6. doi: 10.1021/acsmedchemlett.6b00132. eCollection 2016 Sep 8.

16.

Quantum dot-mediated delivery of siRNA to inhibit sphingomyelinase activities in brain-derived cells.

Getz T, Qin J, Medintz IL, Delehanty JB, Susumu K, Dawson PE, Dawson G.

J Neurochem. 2016 Dec;139(5):872-885. doi: 10.1111/jnc.13841. Epub 2016 Oct 14.

17.

3,4-Dihydroxyphenylalanine Peptides as Nonperturbative Quantum Dot Sensors of Aminopeptidase.

Palomo V, Díaz SA, Stewart MH, Susumu K, Medintz IL, Dawson PE.

ACS Nano. 2016 Jun 28;10(6):6090-9. doi: 10.1021/acsnano.6b01682. Epub 2016 May 27.

18.

Oxime conjugation in protein chemistry: from carbonyl incorporation to nucleophilic catalysis.

Agten SM, Dawson PE, Hackeng TM.

J Pept Sci. 2016 May;22(5):271-9. doi: 10.1002/psc.2874. Epub 2016 Mar 23. Review.

PMID:
27006095
19.

Arginine selective reagents for ligation to peptides and proteins.

Thompson DA, Ng R, Dawson PE.

J Pept Sci. 2016 May;22(5):311-9. doi: 10.1002/psc.2867. Epub 2016 Mar 22.

PMID:
27005702
20.

Click-Based Libraries of SFTI-1 Peptides: New Methods Using Reversed-Phase Silica.

Cistrone PA, Dawson PE.

ACS Comb Sci. 2016 Mar 14;18(3):139-43. doi: 10.1021/acscombsci.5b00195. Epub 2016 Mar 3.

21.

Trimerization of the HIV Transmembrane Domain in Lipid Bilayers Modulates Broadly Neutralizing Antibody Binding.

Reichart TM, Baksh MM, Rhee JK, Fiedler JD, Sligar SG, Finn MG, Zwick MB, Dawson PE.

Angew Chem Int Ed Engl. 2016 Feb 18;55(8):2688-92. doi: 10.1002/anie.201508421. Epub 2016 Jan 22.

22.

Boc-SPPS: Compatible Linker for the Synthesis of Peptide o-Aminoanilides.

Weidmann J, Dimitrijević E, Hoheisel JD, Dawson PE.

Org Lett. 2016 Jan 15;18(2):164-7. doi: 10.1021/acs.orglett.5b03111. Epub 2015 Dec 24.

PMID:
26702477
23.

Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects.

Zhang H, Sturchler E, Zhu J, Nieto A, Cistrone PA, Xie J, He L, Yea K, Jones T, Turn R, Di Stefano PS, Griffin PR, Dawson PE, McDonald PH, Lerner RA.

Nat Commun. 2015 Dec 1;6:8918. doi: 10.1038/ncomms9918.

24.

Controlling the Architecture, Coordination, and Reactivity of Nanoparticle Coating Utilizing an Amino Acid Central Scaffold.

Zhan N, Palui G, Kapur A, Palomo V, Dawson PE, Mattoussi H.

J Am Chem Soc. 2015 Dec 30;137(51):16084-97. doi: 10.1021/jacs.5b10359. Epub 2015 Dec 18.

PMID:
26621185
25.

An L-RNA Aptamer that Binds and Inhibits RNase.

Olea C Jr, Weidmann J, Dawson PE, Joyce GF.

Chem Biol. 2015 Nov 19;22(11):1437-1441. doi: 10.1016/j.chembiol.2015.09.017.

26.

Temperature Dependence of CN and SCN IR Absorptions Facilitates Their Interpretation and Use as Probes of Proteins.

Adhikary R, Zimmermann J, Dawson PE, Romesberg FE.

Anal Chem. 2015 Nov 17;87(22):11561-7. doi: 10.1021/acs.analchem.5b03437. Epub 2015 Nov 2.

PMID:
26523838
27.

The Role of Negative Charge in the Delivery of Quantum Dots to Neurons.

Walters R, Medintz IL, Delehanty JB, Stewart MH, Susumu K, Huston AL, Dawson PE, Dawson G.

ASN Neuro. 2015 Aug 3;7(4). pii: 1759091415592389. doi: 10.1177/1759091415592389. Print 2015 Jul-Aug.

28.

Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526.

Kong L, Kadam RU, Giang E, Ruwona TB, Nieusma T, Culhane JC, Stanfield RL, Dawson PE, Wilson IA, Law M.

J Mol Biol. 2015 Aug 14;427(16):2617-28. doi: 10.1016/j.jmb.2015.06.012. Epub 2015 Jun 30.

29.

Acetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling.

Assem N, Ferreira DJ, Wolan DW, Dawson PE.

Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8665-8. doi: 10.1002/anie.201502607. Epub 2015 Jun 11.

30.

Methods, setup and safe handling for anhydrous hydrogen fluoride cleavage in Boc solid-phase peptide synthesis.

Muttenthaler M, Albericio F, Dawson PE.

Nat Protoc. 2015 Jul;10(7):1067-83. doi: 10.1038/nprot.2015.061. Epub 2015 Jun 18.

PMID:
26086408
31.

Chemical Protein Synthesis Using a Second-Generation N-Acylurea Linker for the Preparation of Peptide-Thioester Precursors.

Blanco-Canosa JB, Nardone B, Albericio F, Dawson PE.

J Am Chem Soc. 2015 Jun 10;137(22):7197-209. doi: 10.1021/jacs.5b03504. Epub 2015 Jun 2.

PMID:
25978693
32.

Photoligation of an amphiphilic polymer with mixed coordination provides compact and reactive quantum dots.

Wang W, Kapur A, Ji X, Safi M, Palui G, Palomo V, Dawson PE, Mattoussi H.

J Am Chem Soc. 2015 Apr 29;137(16):5438-51. doi: 10.1021/jacs.5b00671. Epub 2015 Apr 14.

PMID:
25797052
33.

Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain.

Agarwal R, Domowicz MS, Schwartz NB, Henry J, Medintz I, Delehanty JB, Stewart MH, Susumu K, Huston AL, Deschamps JR, Dawson PE, Palomo V, Dawson G.

ACS Chem Neurosci. 2015 Mar 18;6(3):494-504. doi: 10.1021/acschemneuro.5b00022. Epub 2015 Mar 5.

34.

UV and sunlight driven photoligation of quantum dots: understanding the photochemical transformation of the ligands.

Aldeek F, Hawkins D, Palomo V, Safi M, Palui G, Dawson PE, Alabugin I, Mattoussi H.

J Am Chem Soc. 2015 Feb 25;137(7):2704-14. doi: 10.1021/ja512802x. Epub 2015 Feb 11.

PMID:
25612193
35.

Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor.

Lamberto I, Lechtenberg BC, Olson EJ, Mace PD, Dawson PE, Riedl SJ, Pasquale EB.

ACS Chem Biol. 2014 Dec 19;9(12):2787-95. doi: 10.1021/cb500677x. Epub 2014 Oct 14.

36.

Evidence of an unusual N-H···N hydrogen bond in proteins.

Adhikary R, Zimmermann J, Liu J, Forrest RP, Janicki TD, Dawson PE, Corcelli SA, Romesberg FE.

J Am Chem Soc. 2014 Oct 1;136(39):13474-7. doi: 10.1021/ja503107h. Epub 2014 Sep 16.

PMID:
25226114
37.

Probing the Quenching of Quantum Dot Photoluminescence by Peptide-Labeled Ruthenium(II) Complexes.

Scott AM, Algar WR, Stewart MH, Trammell SA, Blanco-Canosa JB, Dawson PE, Deschamps JR, Goswami R, Oh E, Huston AL, Medintz IL.

J Phys Chem C Nanomater Interfaces. 2014 May 1;118(17):9239-9250. Epub 2014 Apr 22.

38.

Adapter reagents for protein site specific dye labeling.

Thompson DA, Evans EG, Kasza T, Millhauser GL, Dawson PE.

Biopolymers. 2014 May;102(3):273-9. doi: 10.1002/bip.22481.

39.

IR probes of protein microenvironments: utility and potential for perturbation.

Adhikary R, Zimmermann J, Dawson PE, Romesberg FE.

Chemphyschem. 2014 Apr 4;15(5):849-53. doi: 10.1002/cphc.201400017. Epub 2014 Feb 12.

PMID:
24519759
40.

Enhanced catalysis of oxime-based bioconjugations by substituted anilines.

Wendeler M, Grinberg L, Wang X, Dawson PE, Baca M.

Bioconjug Chem. 2014 Jan 15;25(1):93-101. doi: 10.1021/bc400380f. Epub 2013 Dec 17.

PMID:
24320725
41.

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.

Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, Freissmuth M, Gruber CW.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21183-8. doi: 10.1073/pnas.1311183110. Epub 2013 Nov 18.

42.

Competition between Förster resonance energy transfer and electron transfer in stoichiometrically assembled semiconductor quantum dot-fullerene conjugates.

Stewart MH, Huston AL, Scott AM, Oh E, Algar WR, Deschamps JR, Susumu K, Jain V, Prasuhn DE, Blanco-Canosa J, Dawson PE, Medintz IL.

ACS Nano. 2013 Oct 22;7(10):9489-505. doi: 10.1021/nn403872x. Epub 2013 Oct 15.

PMID:
24128175
43.

Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10.

Doyle-Cooper C, Hudson KE, Cooper AB, Ota T, Skog P, Dawson PE, Zwick MB, Schief WR, Burton DR, Nemazee D.

J Immunol. 2013 Sep 15;191(6):3186-3191. doi: 10.4049/jimmunol.1301285. Epub 2013 Aug 12.

44.

Synthesizing and modifying peptides for chemoselective ligation and assembly into quantum dot-peptide bioconjugates.

Algar WR, Blanco-Canosa JB, Manthe RL, Susumu K, Stewart MH, Dawson PE, Medintz IL.

Methods Mol Biol. 2013;1025:47-73. doi: 10.1007/978-1-62703-462-3_5.

PMID:
23918329
45.

Cytotoxicity of quantum dots used for in vitro cellular labeling: role of QD surface ligand, delivery modality, cell type, and direct comparison to organic fluorophores.

Bradburne CE, Delehanty JB, Boeneman Gemmill K, Mei BC, Mattoussi H, Susumu K, Blanco-Canosa JB, Dawson PE, Medintz IL.

Bioconjug Chem. 2013 Sep 18;24(9):1570-83. doi: 10.1021/bc4001917. Epub 2013 Aug 16.

PMID:
23879393
46.

Experimental characterization of electrostatic and conformational heterogeneity in an SH3 domain.

Adhikary R, Zimmermann J, Liu J, Dawson PE, Romesberg FE.

J Phys Chem B. 2013 Oct 24;117(42):13082-9. doi: 10.1021/jp402772x. Epub 2013 Jul 9.

PMID:
23834285
47.

Site-specific cellular delivery of quantum dots with chemoselectively-assembled modular peptides.

Delehanty JB, Blanco-Canosa JB, Bradburne CE, Susumu K, Stewart MH, Prasuhn DE, Dawson PE, Medintz IL.

Chem Commun (Camb). 2013 Sep 18;49(72):7878-80. doi: 10.1039/c3cc42781a. Epub 2013 Jun 12.

PMID:
23759873
48.

Evaluation of diverse peptidyl motifs for cellular delivery of semiconductor quantum dots.

Gemmill KB, Muttenthaler M, Delehanty JB, Stewart MH, Susumu K, Dawson PE, Medintz IL.

Anal Bioanal Chem. 2013 Jul;405(19):6145-54. doi: 10.1007/s00216-013-6982-2. Epub 2013 Jun 4.

PMID:
23732866
49.

Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials.

Boeneman K, Delehanty JB, Blanco-Canosa JB, Susumu K, Stewart MH, Oh E, Huston AL, Dawson G, Ingale S, Walters R, Domowicz M, Deschamps JR, Algar WR, Dimaggio S, Manono J, Spillmann CM, Thompson D, Jennings TL, Dawson PE, Medintz IL.

ACS Nano. 2013 May 28;7(5):3778-96. doi: 10.1021/nn400702r.

50.

Nanoparticle targeting to neurons in a rat hippocampal slice culture model.

Walters R, Kraig RP, Medintz I, Delehanty JB, Stewart MH, Susumu K, Huston AL, Dawson PE, Dawson G.

ASN Neuro. 2012 Oct 23;4(6):383-92. doi: 10.1042/AN20120042.

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