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Kidney microRNA profile in pregnant mice reveals molecular insights into kidney adaptation to pregnancy: A pilot study.

Lee S, Temple FT, Dawson PA.

Mol Genet Metab Rep. 2019 Jun 19;20:100486. doi: 10.1016/j.ymgmr.2019.100486. eCollection 2019 Sep.


Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.

Pepe-Mooney BJ, Dill MT, Alemany A, Ordovas-Montanes J, Matsushita Y, Rao A, Sen A, Miyazaki M, Anakk S, Dawson PA, Ono N, Shalek AK, van Oudenaarden A, Camargo FD.

Cell Stem Cell. 2019 Jul 3;25(1):23-38.e8. doi: 10.1016/j.stem.2019.04.004. Epub 2019 May 9.


Postnatal N-acetylcysteine administration rescues impaired social behaviors and neurogenesis in Slc13a4 haploinsufficient mice.

Zhang Z, Dawson PA, Piper M, Simmons DG.

EBioMedicine. 2019 May;43:435-446. doi: 10.1016/j.ebiom.2019.03.081. Epub 2019 Apr 5.


Study protocol for the Australian autism biobank: an international resource to advance autism discovery research.

Alvares GA, Dawson PA, Dissanayake C, Eapen V, Gratten J, Grove R, Henders A, Heussler H, Lawson L, Masi A, Raymond E, Rose F, Wallace L, Wray NR, Whitehouse AJO; Australian Autism Biobank team.

BMC Pediatr. 2018 Aug 27;18(1):284. doi: 10.1186/s12887-018-1255-z.


Hepatic thyroid hormone receptor β1 agonism: good for lipids, good for bile?

Dawson PA, Parini P.

J Lipid Res. 2018 Sep;59(9):1551-1553. doi: 10.1194/jlr.C088955. Epub 2018 Jul 31. No abstract available.


Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid-Induced Injury.

Ferrebee CB, Li J, Haywood J, Pachura K, Robinson BS, Hinrichs BH, Jones RM, Rao A, Dawson PA.

Cell Mol Gastroenterol Hepatol. 2018 Jan 12;5(4):499-522. doi: 10.1016/j.jcmgh.2018.01.006. eCollection 2018.


Animal models to study bile acid metabolism.

Li J, Dawson PA.

Biochim Biophys Acta Mol Basis Dis. 2019 May 1;1865(5):895-911. doi: 10.1016/j.bbadis.2018.05.011. Epub 2018 May 18. Review.


Natural disaster-related prenatal maternal stress is associated with alterations in placental glucocorticoid system: The QF2011 Queensland Flood Study.

St-Pierre J, Laplante DP, Elgbeili G, Dawson PA, Kildea S, King S, Vaillancourt C.

Psychoneuroendocrinology. 2018 Aug;94:38-48. doi: 10.1016/j.psyneuen.2018.04.027. Epub 2018 Apr 26.


Gene networks associated with non-syndromic intellectual disability.

Lee S, Rudd S, Gratten J, Visscher PM, Prins JB, Dawson PA.

J Neurogenet. 2018 Mar;32(1):6-14. doi: 10.1080/01677063.2017.1404058. Epub 2017 Dec 4.


Structure, organization and tissue expression of the pig SLC13A1 and SLC13A4 sulfate transporter genes.

Barnes SK, Eiby YA, Lee S, Lingwood BE, Dawson PA.

Biochem Biophys Rep. 2017 Apr 13;10:215-223. doi: 10.1016/j.bbrep.2017.04.005. eCollection 2017 Jul.


Organic solute transporter-β (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis.

Sultan M, Rao A, Elpeleg O, Vaz FM, Abu-Libdeh B, Karpen SJ, Dawson PA.

Hepatology. 2018 Aug;68(2):590-598. doi: 10.1002/hep.29516. Epub 2018 May 11.


Hepatic bile acid uptake in humans and mice: Multiple pathways and expanding potential role for gut-liver signaling.

Dawson PA.

Hepatology. 2017 Nov;66(5):1384-1386. doi: 10.1002/hep.29325. Epub 2017 Sep 29. No abstract available.


Will the real bile acid sulfotransferase please stand up? Identification of Sult2a8 as a major hepatic bile acid sulfonating enzyme in mice.

Dawson PA, Setchell KDR.

J Lipid Res. 2017 Jun;58(6):1033-1035. doi: 10.1194/jlr.C077420. Epub 2017 Apr 28. No abstract available.


Molecular analysis of sequence and splice variants of the human SLC13A4 sulfate transporter.

Zhang Z, Aung ZT, Simmons DG, Dawson PA.

Mol Genet Metab. 2017 May;121(1):35-42. doi: 10.1016/j.ymgme.2017.03.010. Epub 2017 Apr 1.


Roles of Ileal ASBT and OSTα-OSTβ in Regulating Bile Acid Signaling.

Dawson PA.

Dig Dis. 2017;35(3):261-266. doi: 10.1159/000450987. Epub 2017 Mar 1. Review.


Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion.

Hasnain SZ, Dawson PA, Lourie R, Hutson P, Tong H, Grencis RK, McGuckin MA, Thornton DJ.

PLoS Pathog. 2017 Feb 13;13(2):e1006218. doi: 10.1371/journal.ppat.1006218. eCollection 2017 Feb.


Review: Nutrient sulfate supply from mother to fetus: Placental adaptive responses during human and animal gestation.

Dawson PA, Richard K, Perkins A, Zhang Z, Simmons DG.

Placenta. 2017 Jun;54:45-51. doi: 10.1016/j.placenta.2017.01.001. Epub 2017 Jan 4. Review.


Genetics and pathophysiology of mammalian sulfate biology.

Langford R, Hurrion E, Dawson PA.

J Genet Genomics. 2017 Jan 20;44(1):7-20. doi: 10.1016/j.jgg.2016.08.001. Epub 2016 Aug 13. Review.


Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.

Rao A, Kosters A, Mells JE, Zhang W, Setchell KD, Amanso AM, Wynn GM, Xu T, Keller BT, Yin H, Banton S, Jones DP, Wu H, Dawson PA, Karpen SJ.

Sci Transl Med. 2016 Sep 21;8(357):357ra122. doi: 10.1126/scitranslmed.aaf4823.


Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.

Arab JP, Karpen SJ, Dawson PA, Arrese M, Trauner M.

Hepatology. 2017 Jan;65(1):350-362. doi: 10.1002/hep.28709. Epub 2016 Aug 4. Review.


Toxic bile and sclerosing cholangitis: Is there a role for pharmacological interruption of the bile acid enterohepatic circulation?

Dawson PA.

Hepatology. 2016 Feb;63(2):363-4. doi: 10.1002/hep.28363. Epub 2016 Jan 6. No abstract available.


Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids.

Ferrebee CB, Dawson PA.

Acta Pharm Sin B. 2015 Mar;5(2):129-34. doi: 10.1016/j.apsb.2015.01.001. Epub 2015 Feb 20. Review.


Inflammation-associated upregulation of the sulfated steroid transporter Slc10a6 in mouse liver and macrophage cell lines.

Kosters A, Abebe DF, Felix JC, Dawson PA, Karpen SJ.

Hepatol Res. 2016 Jul;46(8):794-803. doi: 10.1111/hepr.12609. Epub 2015 Nov 19.


Loss of the sulfate transporter Slc13a4 in placenta causes severe fetal abnormalities and death in mice.

Rakoczy J, Zhang Z, Bowling FG, Dawson PA, Simmons DG.

Cell Res. 2015 Nov;25(11):1273-6. doi: 10.1038/cr.2015.100. Epub 2015 Aug 21. No abstract available.


Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.

Raufman JP, Dawson PA, Rao A, Drachenberg CB, Heath J, Shang AC, Hu S, Zhan M, Polli JE, Cheng K.

Carcinogenesis. 2015 Oct;36(10):1193-200. doi: 10.1093/carcin/bgv107. Epub 2015 Jul 25.


Placental and fetal cysteine dioxygenase gene expression in mouse gestation.

Rakoczy J, Lee S, Weerasekera SJ, Simmons DG, Dawson PA.

Placenta. 2015 Aug;36(8):956-9. doi: 10.1016/j.placenta.2015.06.003. Epub 2015 Jun 19.


QF2011: a protocol to study the effects of the Queensland flood on pregnant women, their pregnancies, and their children's early development.

King S, Kildea S, Austin MP, Brunet A, Cobham VE, Dawson PA, Harris M, Hurrion EM, Laplante DP, McDermott BM, McIntyre HD, O'Hara MW, Schmitz N, Stapleton H, Tracy SK, Vaillancourt C, Dancause KN, Kruske S, Reilly N, Shoo L, Simcock G, Turcotte-Tremblay AM, Yong Ping E.

BMC Pregnancy Childbirth. 2015 May 6;15:109. doi: 10.1186/s12884-015-0539-7.


Reference intervals for plasma sulfate and urinary sulfate excretion in pregnancy.

Dawson PA, Petersen S, Rodwell R, Johnson P, Gibbons K, McWhinney A, Bowling FG, McIntyre HD.

BMC Pregnancy Childbirth. 2015 Apr 17;15:96. doi: 10.1186/s12884-015-0526-z.


The Na(+) -taurocholate cotransporting polypeptide knockout mouse: A new tool for study of bile acids and hepatitis B virus biology.

Kosters A, Dawson PA.

Hepatology. 2015 Jul;62(1):19-21. doi: 10.1002/hep.27780. Epub 2015 Apr 8. No abstract available.


Sulphate in pregnancy.

Dawson PA, Elliott A, Bowling FG.

Nutrients. 2015 Mar 4;7(3):1594-606. doi: 10.3390/nu7031594. Review.


In vitro evidence that phosphatidylcholine protects against indomethacin/bile acid-induced injury to cells.

Dial EJ, Dawson PA, Lichtenberger LM.

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 1;308(3):G217-22. doi: 10.1152/ajpgi.00322.2014. Epub 2014 Dec 4.


Intestinal transport and metabolism of bile acids.

Dawson PA, Karpen SJ.

J Lipid Res. 2015 Jun;56(6):1085-99. doi: 10.1194/jlr.R054114. Epub 2014 Sep 10. Review.


Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging.

Vivian D, Cheng K, Khurana S, Xu S, Dawson PA, Raufman JP, Polli JE.

J Pharm Sci. 2014 Nov;103(11):3782-3792. doi: 10.1002/jps.24131. Epub 2014 Sep 5.


Not all (bile acids) who wander are lost: the first report of a patient with an isolated NTCP defect.

Karpen SJ, Dawson PA.

Hepatology. 2015 Jan;61(1):24-7. doi: 10.1002/hep.27294. Epub 2014 Nov 20. No abstract available.


In vivo performance of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile acid transport.

Vivian D, Cheng K, Khurana S, Xu S, Kriel EH, Dawson PA, Raufman JP, Polli JE.

Mol Pharm. 2014 May 5;11(5):1575-82. doi: 10.1021/mp400740c. Epub 2014 Apr 18.


Bile acids reach out to the spinal cord: new insights to the pathogenesis of itch and analgesia in cholestatic liver disease.

Dawson PA, Karpen SJ.

Hepatology. 2014 Apr;59(4):1638-41. doi: 10.1002/hep.26786. Epub 2014 Feb 14. No abstract available.


The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.


Intestine-specific deletion of SIRT1 in mice impairs DCoH2-HNF-1α-FXR signaling and alters systemic bile acid homeostasis.

Kazgan N, Metukuri MR, Purushotham A, Lu J, Rao A, Lee S, Pratt-Hyatt M, Lickteig A, Csanaky IL, Zhao Y, Dawson PA, Li X.

Gastroenterology. 2014 Apr;146(4):1006-16. doi: 10.1053/j.gastro.2013.12.029. Epub 2013 Dec 31.


Human SLC26A1 gene variants: a pilot study.

Dawson PA, Sim P, Mudge DW, Cowley D.

ScientificWorldJournal. 2013 Oct 22;2013:541710. doi: 10.1155/2013/541710. eCollection 2013.


Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE⁻/⁻ mice.

Lan T, Haywood J, Dawson PA.

Atherosclerosis. 2013 Aug;229(2):374-80. doi: 10.1016/j.atherosclerosis.2013.05.017. Epub 2013 May 28.


A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo "connect".

Won CS, Lan T, Vandermolen KM, Dawson PA, Oberlies NH, Widmer WW, Scarlett YV, Paine MF.

J Clin Pharmacol. 2013 Sep;53(9):982-90. doi: 10.1002/jcph.136. Epub 2013 Jul 23.


Novel regulator of enterohepatic bile acid signaling protects against hypercholesterolemia.

Dawson PA.

Cell Metab. 2013 Jun 4;17(6):816-8. doi: 10.1016/j.cmet.2013.05.005.


Role of sulphate in development.

Dawson PA.

Reproduction. 2013 Jul 29;146(3):R81-9. doi: 10.1530/REP-13-0056. Print 2013 Sep. Review.


Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

Cox AJ, Ng MC, Xu J, Langefeld CD, Koch KL, Dawson PA, Carr JJ, Freedman BI, Hsu FC, Bowden DW.

Atherosclerosis. 2013 Jul;229(1):155-60. doi: 10.1016/j.atherosclerosis.2013.04.008. Epub 2013 Apr 19.


Molecular analysis of the human SLC13A4 sulfate transporter gene promoter.

Jefferis J, Rakoczy J, Simmons DG, Dawson PA.

Biochem Biophys Res Commun. 2013 Mar 29;433(1):79-83. doi: 10.1016/j.bbrc.2013.02.061. Epub 2013 Feb 26.


Human placental sulfate transporter mRNA profiling from term pregnancies identifies abundant SLC13A4 in syncytiotrophoblasts and SLC26A2 in cytotrophoblasts.

Simmons DG, Rakoczy J, Jefferis J, Lourie R, McIntyre HD, Dawson PA.

Placenta. 2013 Apr;34(4):381-4. doi: 10.1016/j.placenta.2013.01.017. Epub 2013 Feb 28.


The effect of medial opening wedge proximal tibial osteotomy on patellofemoral contact.

Javidan P, Adamson GJ, Miller JR, Durand P Jr, Dawson PA, Pink MM, Lee TQ.

Am J Sports Med. 2013 Jan;41(1):80-6. doi: 10.1177/0363546512462810. Epub 2012 Oct 29.


Plasma and urinary sulfate determination in a cohort with autism.

Bowling FG, Heussler HS, McWhinney A, Dawson PA.

Biochem Genet. 2013 Feb;51(1-2):147-53. doi: 10.1007/s10528-012-9550-0. Epub 2012 Oct 27.


Placental, renal, and ileal sulfate transporter gene expression in mouse gestation.

Dawson PA, Rakoczy J, Simmons DG.

Biol Reprod. 2012 Aug 23;87(2):43. doi: 10.1095/biolreprod.111.098749. Print 2012 Aug.


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