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Items: 34


Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria.

Passmore IJ, Letertre MPM, Preston MD, Bianconi I, Harrison MA, Nasher F, Kaur H, Hong HA, Baines SD, Cutting SM, Swann JR, Wren BW, Dawson LF.

PLoS Pathog. 2018 Sep 12;14(9):e1007191. doi: 10.1371/journal.ppat.1007191. eCollection 2018 Sep.


Up-regulation of α1-adrenoceptors in burn and keloid scars.

Drummond PD, Dawson LF, Wood FM, Fear MW.

Burns. 2018 May;44(3):582-588. doi: 10.1016/j.burns.2017.09.010. Epub 2017 Oct 28.


Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation.

Valiente E, Bouché L, Hitchen P, Faulds-Pain A, Songane M, Dawson LF, Donahue E, Stabler RA, Panico M, Morris HR, Bajaj-Elliott M, Logan SM, Dell A, Wren BW.

J Biol Chem. 2016 Dec 2;291(49):25450-25461. Epub 2016 Oct 4.


The potential of metabolomic analysis techniques for the characterisation of α1-adrenergic receptors in cultured N1E-115 mouse neuroblastoma cells.

Wenner MI, Maker GL, Dawson LF, Drummond PD, Mullaney I.

Cytotechnology. 2016 Aug;68(4):1561-75. doi: 10.1007/s10616-015-9915-4. Epub 2015 Sep 25.


Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage.

Peltier J, Shaw HA, Couchman EC, Dawson LF, Yu L, Choudhary JS, Kaever V, Wren BW, Fairweather NF.

J Biol Chem. 2015 Oct 2;290(40):24453-69. doi: 10.1074/jbc.M115.665091. Epub 2015 Aug 17.


Up-regulation of cutaneous α1-adrenoceptors after a burn.

Drummond PD, Dawson LF, Finch PM, Drummond ES, Wood FM, Fear MW.

Burns. 2015 Sep;41(6):1227-34. doi: 10.1016/j.burns.2014.12.015. Epub 2015 Jan 24.


Increased bilateral expression of α1-adrenoceptors on peripheral nerves, blood vessels and keratinocytes does not account for pain or neuroinflammatory changes after distal tibia fracture in rats.

Drummond ES, Dawson LF, Finch PM, Li W, Guo TZ, Kingery WS, Drummond PD.

Neuroscience. 2014 Dec 5;281:99-109. doi: 10.1016/j.neuroscience.2014.09.046. Epub 2014 Oct 5.


Up-regulation of cutaneous α1 -adrenoceptors in complex regional pain syndrome type I.

Finch PM, Drummond ES, Dawson LF, Phillips JK, Drummond PD.

Pain Med. 2014 Nov;15(11):1945-56. doi: 10.1111/pme.12548. Epub 2014 Sep 12.


Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors.

Donahue EH, Dawson LF, Valiente E, Firth-Clark S, Major MR, Littler E, Perrior TR, Wren BW.

BMC Microbiol. 2014 Aug 31;14:219. doi: 10.1186/s12866-014-0219-1.


Activation of cutaneous immune responses in complex regional pain syndrome.

Birklein F, Drummond PD, Li W, Schlereth T, Albrecht N, Finch PM, Dawson LF, Clark JD, Kingery WS.

J Pain. 2014 May;15(5):485-95. doi: 10.1016/j.jpain.2014.01.490. Epub 2014 Jan 23.


Upregulation of α1-adrenoceptors on cutaneous nerve fibres after partial sciatic nerve ligation and in complex regional pain syndrome type II.

Drummond PD, Drummond ES, Dawson LF, Mitchell V, Finch PM, Vaughan CW, Phillips JK.

Pain. 2014 Mar;155(3):606-16. doi: 10.1016/j.pain.2013.12.021. Epub 2013 Dec 14.


Increased expression of cutaneous α1-adrenoceptors after chronic constriction injury in rats.

Drummond ES, Dawson LF, Finch PM, Bennett GJ, Drummond PD.

J Pain. 2014 Feb;15(2):188-96. doi: 10.1016/j.jpain.2013.10.010. Epub 2013 Nov 7.


Characterisation of Clostridium difficile biofilm formation, a role for Spo0A.

Dawson LF, Valiente E, Faulds-Pain A, Donahue EH, Wren BW.

PLoS One. 2012;7(12):e50527. doi: 10.1371/journal.pone.0050527. Epub 2012 Dec 7.


The Clostridium difficile spo0A gene is a persistence and transmission factor.

Deakin LJ, Clare S, Fagan RP, Dawson LF, Pickard DJ, West MR, Wren BW, Fairweather NF, Dougan G, Lawley TD.

Infect Immun. 2012 Aug;80(8):2704-11. doi: 10.1128/IAI.00147-12. Epub 2012 May 21.


Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations.

Stabler RA, Dawson LF, Valiente E, Cairns MD, Martin MJ, Donahue EH, Riley TV, Songer JG, Kuijper EJ, Dingle KE, Wren BW.

PLoS One. 2012;7(3):e31559. doi: 10.1371/journal.pone.0031559. Epub 2012 Mar 2.


Hypervirulent Clostridium difficile PCR-ribotypes exhibit resistance to widely used disinfectants.

Dawson LF, Valiente E, Donahue EH, Birchenough G, Wren BW.

PLoS One. 2011;6(10):e25754. doi: 10.1371/journal.pone.0025754. Epub 2011 Oct 25.


Usefulness of [18F]-DA and [18F]-DOPA for PET imaging in a mouse model of pheochromocytoma.

Martiniova L, Cleary S, Lai EW, Kiesewetter DO, Seidel J, Dawson LF, Phillips JK, Thomasson D, Chen X, Eisenhofer G, Powers JF, Kvetnansky R, Pacak K.

Nucl Med Biol. 2012 Feb;39(2):215-26. doi: 10.1016/j.nucmedbio.2011.07.007. Epub 2011 Sep 29.


Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage.

Valiente E, Dawson LF, Cairns MD, Stabler RA, Wren BW.

J Med Microbiol. 2012 Jan;61(Pt 1):49-56. doi: 10.1099/jmm.0.036194-0. Epub 2011 Sep 8.


A preliminary investigation of the reinnervation and return of sensory function in burn patients treated with INTEGRA®.

Anderson JR, Fear MW, Phillips JK, Dawson LF, Wallace H, Wood FM, Rea SM.

Burns. 2011 Nov;37(7):1101-8. doi: 10.1016/j.burns.2011.04.002. Epub 2011 May 4.


The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains.

Dawson LF, Donahue EH, Cartman ST, Barton RH, Bundy J, McNerney R, Minton NP, Wren BW.

BMC Microbiol. 2011 Apr 28;11:86. doi: 10.1186/1471-2180-11-86.


In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions.

Stabler RA, Valiente E, Dawson LF, He M, Parkhill J, Wren BW.

Gut Microbes. 2010 Jul;1(4):269-276. Epub 2010 Mar 16.


Changes in cutaneous innervation in patients with chronic pain after burns.

Hamed K, Giles N, Anderson J, Phillips JK, Dawson LF, Drummond P, Wallace H, Wood FM, Rea SM, Fear MW.

Burns. 2011 Jun;37(4):631-7. doi: 10.1016/j.burns.2010.11.010. Epub 2011 Jan 22.


Expression of α1-adrenoceptors on peripheral nociceptive neurons.

Dawson LF, Phillips JK, Finch PM, Inglis JJ, Drummond PD.

Neuroscience. 2011 Feb 23;175:300-14. doi: 10.1016/j.neuroscience.2010.11.064. Epub 2010 Dec 20.


SigG does not control gene expression in response to DNA damage in Mycobacterium tuberculosis H37Rv.

Smollett KL, Dawson LF, Davis EO.

J Bacteriol. 2011 Feb;193(4):1007-11. doi: 10.1128/JB.01241-10. Epub 2010 Dec 17.


Evolutionary dynamics of Clostridium difficile over short and long time scales.

He M, Sebaihia M, Lawley TD, Stabler RA, Dawson LF, Martin MJ, Holt KE, Seth-Smith HM, Quail MA, Rance R, Brooks K, Churcher C, Harris D, Bentley SD, Burrows C, Clark L, Corton C, Murray V, Rose G, Thurston S, van Tonder A, Walker D, Wren BW, Dougan G, Parkhill J.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7527-32. doi: 10.1073/pnas.0914322107. Epub 2010 Apr 5.


Systemic decreases in cutaneous innervation after burn injury.

Anderson JR, Zorbas JS, Phillips JK, Harrison JL, Dawson LF, Bolt SE, Rea SM, Klatte JE, Paus R, Zhu B, Giles NL, Drummond PD, Wood FM, Fear MW.

J Invest Dermatol. 2010 Jul;130(7):1948-51. doi: 10.1038/jid.2010.47. Epub 2010 Mar 25. No abstract available.


RecA-independent DNA damage induction of Mycobacterium tuberculosis ruvC despite an appropriately located SOS box.

Dawson LF, Dillury J, Davis EO.

J Bacteriol. 2010 Jan;192(2):599-603. doi: 10.1128/JB.01066-09. Epub 2009 Nov 13.


Clostridium difficile--a continually evolving and problematic pathogen.

Dawson LF, Valiente E, Wren BW.

Infect Genet Evol. 2009 Dec;9(6):1410-7. doi: 10.1016/j.meegid.2009.06.005. Epub 2009 Jun 16.


Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux.

Stabler RA, Dawson LF, Oyston PC, Titball RW, Wade J, Hinds J, Witney AA, Wren BW.

BMC Microbiol. 2008 Oct 9;8:177. doi: 10.1186/1471-2180-8-177.


Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences.

Stabler RA, Dawson LF, Phua LT, Wren BW.

J Med Microbiol. 2008 Jun;57(Pt 6):771-5. doi: 10.1099/jmm.0.47743-0.


Assessing the role of p-cresol tolerance in Clostridium difficile.

Dawson LF, Stabler RA, Wren BW.

J Med Microbiol. 2008 Jun;57(Pt 6):745-9. doi: 10.1099/jmm.0.47744-0.


Influence of flanking homology and insert size on the transformation frequency of Acinetobacter baylyi BD413.

Simpson DJ, Dawson LF, Fry JC, Rogers HJ, Day MJ.

Environ Biosafety Res. 2007 Jan-Jun;6(1-2):55-69. Epub 2007 Sep 12.


The mycobacterium-specific gene Rv2719c is DNA damage inducible independently of RecA.

Brooks PC, Dawson LF, Rand L, Davis EO.

J Bacteriol. 2006 Aug;188(16):6034-8.


Genomic organization and amplification of the human desmosomal cadherin genes DSC1 and DSC3, encoding desmocollin types 1 and 3.

Whittock NV, Hunt DM, Rickman L, Malhi S, Vogazianou AP, Dawson LF, Eady RA, Buxton RS, McGrath JA.

Biochem Biophys Res Commun. 2000 Sep 24;276(2):454-60.


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