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Items: 1 to 50 of 438

1.

Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide.

Faridi A, Sun Y, Mortimer M, Aranha RR, Nandakumar A, Li Y, Javed I, Kakinen A, Fan Q, Purcell AW, Davis TP, Ding F, Faridi P, Ke PC.

Nano Res. 2019 Nov;12(11):2827-2834. doi: 10.1007/s12274-019-2520-7. Epub 2019 Sep 26.

2.

A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.

Ramírez-García PD, Retamal JS, Shenoy P, Imlach W, Sykes M, Truong N, Constandil L, Pelissier T, Nowell CJ, Khor SY, Layani LM, Lumb C, Poole DP, Lieu T, Stewart GD, Mai QN, Jensen DD, Latorre R, Scheff NN, Schmidt BL, Quinn JF, Whittaker MR, Veldhuis NA, Davis TP, Bunnett NW.

Nat Nanotechnol. 2019 Nov 4. doi: 10.1038/s41565-019-0568-x. [Epub ahead of print]

PMID:
31686009
3.

Engineering Organic/Inorganic Nanohybrids through RAFT Polymerization for Biomedical Applications.

Huang X, Hu J, Li Y, Xin F, Qiao R, Davis TP.

Biomacromolecules. 2019 Nov 1. doi: 10.1021/acs.biomac.9b01158. [Epub ahead of print]

PMID:
31638375
4.

An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform.

Grace JL, Amado M, Reid JC, Elliott AG, Landersdorfer CB, Truong NP, Kempe K, Cooper MA, Davis TP, Montembault V, Pascual S, Fontaine L, Velkov T, Quinn JF, Whittaker MR.

J Mater Chem B. 2019 Nov 21;7(43):6796-6809. doi: 10.1039/c9tb01624d. Epub 2019 Oct 11.

PMID:
31603181
5.

Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid.

Faridi A, Yang W, Kelly HG, Wang C, Faridi P, Purcell AW, Davis TP, Chen P, Kent SJ, Ke PC.

Biomacromolecules. 2019 Nov 11;20(11):4208-4217. doi: 10.1021/acs.biomac.9b01116. Epub 2019 Oct 22.

PMID:
31600059
6.

Single-Molecular Heteroamyloidosis of Human Islet Amyloid Polypeptide.

Kakinen A, Xing Y, Hegoda Arachchi N, Javed I, Feng L, Faridi A, Douek AM, Sun Y, Kaslin J, Davis TP, Higgins MJ, Ding F, Ke PC.

Nano Lett. 2019 Sep 11;19(9):6535-6546. doi: 10.1021/acs.nanolett.9b02771. Epub 2019 Aug 29.

PMID:
31455083
7.

Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy.

Javed I, Peng G, Xing Y, Yu T, Zhao M, Kakinen A, Faridi A, Parish CL, Ding F, Davis TP, Ke PC, Lin S.

Nat Commun. 2019 Aug 22;10(1):3780. doi: 10.1038/s41467-019-11762-0.

8.

Carboxylated Cy5-Labeled Comb Polymers Passively Diffuse the Cell Membrane and Target Mitochondria.

Mahmoud AM, de Jongh PAJM, Briere S, Chen M, Nowell CJ, Johnston APR, Davis TP, Haddleton DM, Kempe K.

ACS Appl Mater Interfaces. 2019 Aug 28;11(34):31302-31310. doi: 10.1021/acsami.9b09395. Epub 2019 Aug 16.

PMID:
31369228
9.

Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore.

Sun Y, Kakinen A, Zhang C, Yang Y, Faridi A, Davis TP, Cao W, Ke PC, Ding F.

Nanoscale. 2019 Jun 20;11(24):11933-11945. doi: 10.1039/c9nr02407g.

PMID:
31188372
10.

Mitigation of Amyloidosis with Nanomaterials.

Ke PC, Pilkington EH, Sun Y, Javed I, Kakinen A, Peng G, Ding F, Davis TP.

Adv Mater. 2019 Jun 11:e1901690. doi: 10.1002/adma.201901690. [Epub ahead of print] Review.

PMID:
31183916
11.

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates.

Sun Y, Kakinen A, Xing Y, Faridi P, Nandakumar A, Purcell AW, Davis TP, Ke PC, Ding F.

Small. 2019 May;15(18):e1805166. doi: 10.1002/smll.201805166. Epub 2019 Mar 25.

PMID:
30908844
12.

Understanding Effects of PAMAM Dendrimer Size and Surface Chemistry on Serum Protein Binding with Discrete Molecular Dynamics Simulations.

Wang B, Sun Y, Davis TP, Ke PC, Wu Y, Ding F.

ACS Sustain Chem Eng. 2018 Sep 4;6(9):11704-11715. doi: 10.1021/acssuschemeng.8b01959. Epub 2018 Jul 31.

13.

Distribution of insulin in trigeminal nerve and brain after intranasal administration.

Lochhead JJ, Kellohen KL, Ronaldson PT, Davis TP.

Sci Rep. 2019 Feb 22;9(1):2621. doi: 10.1038/s41598-019-39191-5.

14.

Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles.

Klein T, Parkin J, de Jongh PAJM, Esser L, Sepehrizadeh T, Zheng G, De Veer M, Alt K, Hagemeyer CE, Haddleton DM, Davis TP, Thelakkat M, Kempe K.

Macromol Rapid Commun. 2019 May;40(10):e1800911. doi: 10.1002/marc.201800911. Epub 2019 Feb 12.

PMID:
30747472
15.

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.

Somers K, Wen VW, Middlemiss SMC, Osborne B, Forgham H, Jung M, Karsa M, Clifton M, Bongers A, Gao J, Mayoh C, Raoufi-Rad N, Kusnadi EP, Hannan KM, Scott DA, Kwek A, Liu B, Flemming C, Chudakova DA, Pandher R, Failes TW, Lim J, Angeli A, Osterman AL, Imamura T, Kees UR, Supuran CT, Pearson RB, Hannan RD, Davis TP, McCarroll J, Kavallaris M, Turner N, Gudkov AV, Haber M, Norris MD, Henderson MJ.

Oncogene. 2019 May;38(20):3824-3842. doi: 10.1038/s41388-018-0666-5. Epub 2019 Jan 22.

16.

Probing the Aggregation and Immune Response of Human Islet Amyloid Polypeptides with Ligand-Stabilized Gold Nanoparticles.

Javed I, He J, Kakinen A, Faridi A, Yang W, Davis TP, Ke PC, Chen P.

ACS Appl Mater Interfaces. 2019 Mar 20;11(11):10462-10471. doi: 10.1021/acsami.8b19506. Epub 2019 Feb 1.

PMID:
30663303
17.

Physical and Toxicological Profiles of Human IAPP Amyloids and Plaques.

Kakinen A, Sun Y, Javed I, Faridi A, Pilkington EH, Faridi P, Purcell AW, Zhou R, Ding F, Lin S, Chun Ke P, Davis TP.

Sci Bull (Beijing). 2019 Jan 15;64(1):26-35. doi: 10.1016/j.scib.2018.11.012. Epub 2018 Nov 22.

PMID:
30662791
18.

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Salman RA, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV.

Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222.

19.

Frequency of 30-Day Readmission and Its Causes After Endovascular Aneurysm Intervention of Abdominal Aortic Aneurysm (from the Nationwide Readmission Database).

Atti V, Nalluri N, Kumar V, Tabet R, Yandrapalli S, Edla S, Tripathi A, Patel NJ, Dave M, Aronow WS, Basir MB, Davis TP, Drachman DE, Bhatt DL.

Am J Cardiol. 2019 Mar 15;123(6):986-994. doi: 10.1016/j.amjcard.2018.12.006. Epub 2018 Dec 19.

PMID:
30598244
20.

Synthesis and identification of novel pyridazinylpyrazolone based diazo compounds as inhibitors of human islet amyloid polypeptide aggregation.

Farrukh SUB, Javed I, Ather AQ, Emwas AH, Alazmi M, Gao X, Chotana GA, Davis TP, Ke PC, Saleem RSZ.

Bioorg Chem. 2019 Mar;84:339-346. doi: 10.1016/j.bioorg.2018.11.039. Epub 2018 Nov 28.

PMID:
30530075
21.

Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide.

Sun Y, Kakinen A, Xing Y, Pilkington EH, Davis TP, Ke PC, Ding F.

Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1;1865(2):434-444. doi: 10.1016/j.bbadis.2018.11.021. Epub 2018 Nov 28.

PMID:
30502402
22.

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics.

Wang S, Li F, Qiao R, Hu X, Liao H, Chen L, Wu J, Wu H, Zhao M, Liu J, Chen R, Ma X, Kim D, Sun J, Davis TP, Chen C, Tian J, Hyeon T, Ling D.

ACS Nano. 2018 Dec 26;12(12):12380-12392. doi: 10.1021/acsnano.8b06399. Epub 2018 Dec 11.

PMID:
30495919
23.

Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke.

Lyden P, Pryor KE, Coffey CS, Cudkowicz M, Conwit R, Jadhav A, Sawyer RN Jr, Claassen J, Adeoye O, Song S, Hannon P, Rost NS, Hinduja A, Torbey M, Lee JM, Benesch C, Rippee M, Rymer M, Froehler MT, Clarke Haley E, Johnson M, Yankey J, Magee K, Qidwai J, Levy H, Mark Haacke E, Fawaz M, Davis TP, Toga AW, Griffin JH, Zlokovic BV; NeuroNEXT Clinical Trials Network NN104 Investigators.

Ann Neurol. 2019 Jan;85(1):125-136. doi: 10.1002/ana.25383. Epub 2019 Jan 7.

PMID:
30450637
24.

Mitigating Human IAPP Amyloidogenesis In Vivo with Chiral Silica Nanoribbons.

Faridi A, Sun Y, Okazaki Y, Peng G, Gao J, Kakinen A, Faridi P, Zhao M, Javed I, Purcell AW, Davis TP, Lin S, Oda R, Ding F, Ke PC.

Small. 2018 Nov;14(47):e1802825. doi: 10.1002/smll.201802825. Epub 2018 Oct 7.

25.

Exploiting Macromolecular Design To Optimize the Antibacterial Activity of Alkylated Cationic Oligomers.

Grace JL, Schneider-Futschik EK, Elliott AG, Amado M, Truong NP, Cooper MA, Li J, Davis TP, Quinn JF, Velkov T, Whittaker MR.

Biomacromolecules. 2018 Dec 10;19(12):4629-4640. doi: 10.1021/acs.biomac.8b01317. Epub 2018 Nov 6.

PMID:
30359516
26.

Bioconjugation and Fluorescence Labeling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-Terminal Polymers.

Qiao R, Esser L, Fu C, Zhang C, Hu J, Ramírez-Arcía P, Li Y, Quinn JF, Whittaker MR, Whittaker AK, Davis TP.

Biomacromolecules. 2018 Nov 12;19(11):4423-4429. doi: 10.1021/acs.biomac.8b01282. Epub 2018 Oct 23.

PMID:
30350948
27.

Graphene quantum dots against human IAPP aggregation and toxicity in vivo.

Wang M, Sun Y, Cao X, Peng G, Javed I, Kakinen A, Davis TP, Lin S, Liu J, Ding F, Ke PC.

Nanoscale. 2018 Nov 1;10(42):19995-20006. doi: 10.1039/c8nr07180b.

28.

Acute pain alters P-glycoprotein-containing protein complexes in rat cerebral microvessels: Implications for P-glycoprotein trafficking.

Tome ME, Jarvis CK, Schaefer CP, Jacobs LM, Herndon JM, Hunn KC, Arkwright NB, Kellohen KL, Mierau PC, Davis TP.

J Cereb Blood Flow Metab. 2018 Dec;38(12):2209-2222. doi: 10.1177/0271678X18803623. Epub 2018 Oct 22.

PMID:
30346224
29.

Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity.

Yang J, Reilly BG, Davis TP, Ronaldson PT.

Pharmaceutics. 2018 Oct 18;10(4). pii: E192. doi: 10.3390/pharmaceutics10040192. Review.

30.

Nanoscale inhibition of polymorphic and ambidextrous IAPP amyloid aggregation with small molecules.

Kakinen A, Adamcik J, Wang B, Ge X, Mezzenga R, Davis TP, Ding F, Ke PC.

Nano Res. 2018 Jul;11(7):3636-3647. doi: 10.1007/s12274-017-1930-7. Epub 2018 Aug 2.

31.

Minimum information reporting in bio-nano experimental literature.

Faria M, Björnmalm M, Thurecht KJ, Kent SJ, Parton RG, Kavallaris M, Johnston APR, Gooding JJ, Corrie SR, Boyd BJ, Thordarson P, Whittaker AK, Stevens MM, Prestidge CA, Porter CJH, Parak WJ, Davis TP, Crampin EJ, Caruso F.

Nat Nanotechnol. 2018 Sep;13(9):777-785. doi: 10.1038/s41565-018-0246-4. Epub 2018 Sep 6. Review.

32.

Biologically Targeted Magnetic Hyperthermia: Potential and Limitations.

Chang D, Lim M, Goos JACM, Qiao R, Ng YY, Mansfeld FM, Jackson M, Davis TP, Kavallaris M.

Front Pharmacol. 2018 Aug 2;9:831. doi: 10.3389/fphar.2018.00831. eCollection 2018. Review.

33.

Controlling Nanomaterial Size and Shape for Biomedical Applications via Polymerization-Induced Self-Assembly.

Khor SY, Quinn JF, Whittaker MR, Truong NP, Davis TP.

Macromol Rapid Commun. 2019 Jan;40(2):e1800438. doi: 10.1002/marc.201800438. Epub 2018 Aug 9. Review.

PMID:
30091816
34.

In Vivo Mitigation of Amyloidogenesis through Functional-Pathogenic Double-Protein Coronae.

Javed I, Yu T, Peng G, Sánchez-Ferrer A, Faridi A, Kakinen A, Zhao M, Mezzenga R, Davis TP, Lin S, Ke PC.

Nano Lett. 2018 Sep 12;18(9):5797-5804. doi: 10.1021/acs.nanolett.8b02446. Epub 2018 Aug 13.

PMID:
30088935
35.

Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery.

Cottier KE, Galloway EA, Calabrese EC, Tome ME, Liktor-Busa E, Kim J, Davis TP, Vanderah TW, Largent-Milnes TM.

eNeuro. 2018 Jul 16;5(4). pii: ENEURO.0116-18.2018. doi: 10.1523/ENEURO.0116-18.2018. eCollection 2018 Jul-Aug.

36.

Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly.

Khor SY, Vu MN, Pilkington EH, Johnston APR, Whittaker MR, Quinn JF, Truong NP, Davis TP.

Small. 2018 Aug;14(34):e1801702. doi: 10.1002/smll.201801702. Epub 2018 Jul 25.

PMID:
30043521
37.

Organic Arsenicals as Functional Motifs in Polymer and Biomaterials Science.

Tanaka J, Davis TP, Wilson P.

Macromol Rapid Commun. 2018 Oct;39(19):e1800205. doi: 10.1002/marc.201800205. Epub 2018 May 28. Review.

PMID:
29806240
38.

Recent Advances in Magnetic Nanoparticle-based Molecular Probes for Hepatocellular Carcinoma Diagnosis and Therapy.

Zhang Q, Wang S, Qiao R, Whittaker MR, Quinn JF, Davis TP, Li H.

Curr Pharm Des. 2018;24(21):2432-2437. doi: 10.2174/1381612824666180516111939. Review.

PMID:
29788872
39.

Profiling the Serum Protein Corona of Fibrillar Human Islet Amyloid Polypeptide.

Pilkington EH, Gustafsson OJR, Xing Y, Hernandez-Fernaud J, Zampronio C, Kakinen A, Faridi A, Ding F, Wilson P, Ke PC, Davis TP.

ACS Nano. 2018 Jun 26;12(6):6066-6078. doi: 10.1021/acsnano.8b02346. Epub 2018 May 16.

40.

Microfluidic Mass Production of Stabilized and Stealthy Liquid Metal Nanoparticles.

Tang SY, Qiao R, Yan S, Yuan D, Zhao Q, Yun G, Davis TP, Li W.

Small. 2018 May;14(21):e1800118. doi: 10.1002/smll.201800118. Epub 2018 Apr 22.

PMID:
29682878
41.

Human plasma proteome association and cytotoxicity of nano-graphene oxide grafted with stealth polyethylene glycol and poly(2-ethyl-2-oxazoline).

Wang M, Gustafsson OJR, Siddiqui G, Javed I, Kelly HG, Blin T, Yin H, Kent SJ, Creek DJ, Kempe K, Ke PC, Davis TP.

Nanoscale. 2018 Jun 14;10(23):10863-10875. doi: 10.1039/c8nr00835c.

PMID:
29658020
42.

Nano-assemblies of cationic mPEG brush block copolymers with gadolinium polyoxotungstate [Gd(W5O18)2]9- form stable, high relaxivity MRI contrast agents.

Ly J, Li Y, Vu MN, Moffat BA, Jack KS, Quinn JF, Whittaker MR, Davis TP.

Nanoscale. 2018 Apr 19;10(15):7270-7280. doi: 10.1039/c8nr01544a.

PMID:
29632934
43.

Chronic morphine exposure potentiates p-glycoprotein trafficking from nuclear reservoirs in cortical rat brain microvessels.

Schaefer CP, Arkwright NB, Jacobs LM, Jarvis CK, Hunn KC, Largent-Milnes TM, Tome ME, Davis TP.

PLoS One. 2018 Feb 7;13(2):e0192340. doi: 10.1371/journal.pone.0192340. eCollection 2018.

44.

17-β-Estradiol induces spreading depression and pain behavior in alert female rats.

Sandweiss AJ, Cottier KE, McIntosh MI, Dussor G, Davis TP, Vanderah TW, Largent-Milnes TM.

Oncotarget. 2017 Dec 9;8(69):114109-114122. doi: 10.18632/oncotarget.23141. eCollection 2017 Dec 26.

45.

Serum albumin impedes the amyloid aggregation and hemolysis of human islet amyloid polypeptide and alpha synuclein.

Kakinen A, Javed I, Faridi A, Davis TP, Ke PC.

Biochim Biophys Acta Biomembr. 2018 Jan 27. pii: S0005-2736(18)30021-X. doi: 10.1016/j.bbamem.2018.01.015. [Epub ahead of print]

46.

Association of Anemia With Outcomes in Patients Undergoing Percutaneous Peripheral Vascular Intervention: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2 VIC).

Ambulgekar NV, Grey SF, Rosman HS, Othman H, Davis TP, Nypaver TJ, Schreiber T, Yamasaki H, Lalonde TA, Henke PK, Gurm HS, Mehta RH, Grossman PM; Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) Investigators.

J Invasive Cardiol. 2018 Jan;30(1):35-42.

47.

Uptake and transcytosis of functionalized superparamagnetic iron oxide nanoparticles in an in vitro blood brain barrier model.

Ivask A, Pilkington EH, Blin T, Käkinen A, Vija H, Visnapuu M, Quinn JF, Whittaker MR, Qiao R, Davis TP, Ke PC, Voelcker NH.

Biomater Sci. 2018 Jan 30;6(2):314-323. doi: 10.1039/c7bm01012e.

PMID:
29239410
48.

Modulating protein amyloid aggregation with nanomaterials.

Wang B, Pilkington EH, Sun Y, Davis TP, Ke PC, Ding F.

Environ Sci Nano. 2017 Sep 1;4(9):1772-1783. doi: 10.1039/C7EN00436B. Epub 2017 Jul 28.

49.

A Decade of the Protein Corona.

Ke PC, Lin S, Parak WJ, Davis TP, Caruso F.

ACS Nano. 2017 Dec 26;11(12):11773-11776. doi: 10.1021/acsnano.7b08008. Epub 2017 Dec 5.

PMID:
29206030
50.

The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse.

Schaefer CP, Tome ME, Davis TP.

Fluids Barriers CNS. 2017 Nov 29;14(1):32. doi: 10.1186/s12987-017-0080-3. Review.

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