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Items: 1 to 50 of 98


Evolutionary trends of neuropeptide signaling in beetles - A comparative analysis of Coleopteran transcriptomic and genomic data.

Pandit AA, Davies SA, Smagghe G, Dow JAT.

Insect Biochem Mol Biol. 2019 Aug 27;114:103227. doi: 10.1016/j.ibmb.2019.103227. [Epub ahead of print]


Targeted renal knockdown of Na+/H+ exchanger regulatory factor Sip1 produces uric acid nephrolithiasis in Drosophila.

Ghimire S, Terhzaz S, Cabrero P, Romero MF, Davies SA, Dow JAT.

Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F930-F940. doi: 10.1152/ajprenal.00551.2018. Epub 2019 Jul 31.


Application of ER Stress Biomarkers to Predict Formulated Monoclonal Antibody Stability.

Talbot NE, Mead EJ, Davies SA, Uddin S, Smales CM.

Biotechnol J. 2019 Oct;14(10):e1900024. doi: 10.1002/biot.201900024. Epub 2019 Jun 28.


Novel roles for GATAe in growth, maintenance and proliferation of cell populations in the Drosophila renal tubule.

Martínez-Corrales G, Cabrero P, Dow JAT, Terhzaz S, Davies SA.

Development. 2019 May 9;146(9). pii: dev178087. doi: 10.1242/dev.178087.


Epithelial Function in the Drosophila Malpighian Tubule: An In Vivo Renal Model.

Davies SA, Cabrero P, Marley R, Corrales GM, Ghimire S, Dornan AJ, Dow JAT.

Methods Mol Biol. 2019;1926:203-221. doi: 10.1007/978-1-4939-9021-4_17.


Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid (Myzus persicae and Macrosiphum rosae) stress tolerance.

Alford L, Marley R, Dornan A, Pierre JS, Dow JA, Nachman RJ, Davies SA.

Pest Manag Sci. 2019 Jun;75(6):1750-1759. doi: 10.1002/ps.5372. Epub 2019 Mar 21.


New views on the Malpighian tubule from post-genomic technologies.

Dow JA, Pandit A, Davies SA.

Curr Opin Insect Sci. 2018 Oct;29:7-11. doi: 10.1016/j.cois.2018.05.010. Epub 2018 May 25. Review.


Coordinated RNA-Seq and peptidomics identify neuropeptides and G-protein coupled receptors (GPCRs) in the large pine weevil Hylobius abietis, a major forestry pest.

Pandit AA, Ragionieri L, Marley R, Yeoh JGC, Inward DJG, Davies SA, Predel R, Dow JAT.

Insect Biochem Mol Biol. 2018 Oct;101:94-107. doi: 10.1016/j.ibmb.2018.08.003. Epub 2018 Aug 27.


FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data.

Leader DP, Krause SA, Pandit A, Davies SA, Dow JAT.

Nucleic Acids Res. 2018 Jan 4;46(D1):D809-D815. doi: 10.1093/nar/gkx976.


Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila.

Zandawala M, Marley R, Davies SA, Nässel DR.

Cell Mol Life Sci. 2018 Mar;75(6):1099-1115. doi: 10.1007/s00018-017-2682-y. Epub 2017 Oct 17.


Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii.

Terhzaz S, Alford L, Yeoh JG, Marley R, Dornan AJ, Dow JA, Davies SA.

Pest Manag Sci. 2018 Apr;74(4):800-810. doi: 10.1002/ps.4663. Epub 2017 Aug 29.


DINeR: Database for Insect Neuropeptide Research.

Yeoh JGC, Pandit AA, Zandawala M, Nässel DR, Davies SA, Dow JAT.

Insect Biochem Mol Biol. 2017 Jul;86:9-19. doi: 10.1016/j.ibmb.2017.05.001. Epub 2017 May 11.


Molecular mechanism and functional significance of acid generation in the Drosophila midgut.

Overend G, Luo Y, Henderson L, Douglas AE, Davies SA, Dow JA.

Sci Rep. 2016 Jun 2;6:27242. doi: 10.1038/srep27242.


The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules.

Halberg KA, Rainey SM, Veland IR, Neuert H, Dornan AJ, Klämbt C, Davies SA, Dow JA.

Nat Commun. 2016 Apr 13;7:11266. doi: 10.1038/ncomms11266.


The corticotropin-releasing factor-like diuretic hormone 44 (DH44) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster.

Cannell E, Dornan AJ, Halberg KA, Terhzaz S, Dow JAT, Davies SA.

Peptides. 2016 Jun;80:96-107. doi: 10.1016/j.peptides.2016.02.004. Epub 2016 Feb 17.


The capacity to maintain ion and water homeostasis underlies interspecific variation in Drosophila cold tolerance.

MacMillan HA, Andersen JL, Davies SA, Overgaard J.

Sci Rep. 2015 Dec 18;5:18607. doi: 10.1038/srep18607.


What is an epitheliome, anyway?

Dow JA, Davies SA.

Insect Biochem Mol Biol. 2015 Dec;67:1. doi: 10.1016/j.ibmb.2015.10.013. Epub 2015 Oct 28. No abstract available.


Metabolomic profiling of permethrin-treated Drosophila melanogaster identifies a role for tryptophan catabolism in insecticide survival.

Brinzer RA, Henderson L, Marchiondo AA, Woods DJ, Davies SA, Dow JA.

Insect Biochem Mol Biol. 2015 Dec;67:74-86. doi: 10.1016/j.ibmb.2015.09.009. Epub 2015 Oct 22.


Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities.

Chintapalli VR, Kato A, Henderson L, Hirata T, Woods DJ, Overend G, Davies SA, Romero MF, Dow JA.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11720-5. doi: 10.1073/pnas.1508031112. Epub 2015 Aug 31.


A novel role of Drosophila cytochrome P450-4e3 in permethrin insecticide tolerance.

Terhzaz S, Cabrero P, Brinzer RA, Halberg KA, Dow JA, Davies SA.

Insect Biochem Mol Biol. 2015 Dec;67:38-46. doi: 10.1016/j.ibmb.2015.06.002. Epub 2015 Jun 12.


A comprehensive transcriptomic view of renal function in the malaria vector, Anopheles gambiae.

Overend G, Cabrero P, Halberg KA, Ranford-Cartwright LC, Woods DJ, Davies SA, Dow JA.

Insect Biochem Mol Biol. 2015 Dec;67:47-58. doi: 10.1016/j.ibmb.2015.05.007. Epub 2015 May 21.


Tracing the evolutionary origins of insect renal function.

Halberg KA, Terhzaz S, Cabrero P, Davies SA, Dow JA.

Nat Commun. 2015 Apr 21;6:6800. doi: 10.1038/ncomms7800.


Insect capa neuropeptides impact desiccation and cold tolerance.

Terhzaz S, Teets NM, Cabrero P, Henderson L, Ritchie MG, Nachman RJ, Dow JA, Denlinger DL, Davies SA.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2882-7. doi: 10.1073/pnas.1501518112. Epub 2015 Feb 17.


Chloride channels in stellate cells are essential for uniquely high secretion rates in neuropeptide-stimulated Drosophila diuresis.

Cabrero P, Terhzaz S, Romero MF, Davies SA, Blumenthal EM, Dow JA.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14301-6. doi: 10.1073/pnas.1412706111. Epub 2014 Sep 16.


Cell signalling mechanisms for insect stress tolerance.

Davies SA, Cabrero P, Overend G, Aitchison L, Sebastian S, Terhzaz S, Dow JA.

J Exp Biol. 2014 Jan 1;217(Pt 1):119-28. doi: 10.1242/jeb.090571. Review.


The D. melanogaster capa-1 neuropeptide activates renal NF-kB signaling.

Terhzaz S, Overend G, Sebastian S, Dow JA, Davies SA.

Peptides. 2014 Mar;53:218-24. doi: 10.1016/j.peptides.2013.08.004. Epub 2013 Aug 14.


Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epithelia.

Chintapalli VR, Wang J, Herzyk P, Davies SA, Dow JA.

BMC Genomics. 2013 Jul 30;14:518. doi: 10.1186/1471-2164-14-518. Review.


Signaling by Drosophila capa neuropeptides.

Davies SA, Cabrero P, Povsic M, Johnston NR, Terhzaz S, Dow JA.

Gen Comp Endocrinol. 2013 Jul 1;188:60-6. doi: 10.1016/j.ygcen.2013.03.012. Epub 2013 Apr 1. Review.


Phosphodiesterase-8A binds to and regulates Raf-1 kinase.

Brown KM, Day JP, Huston E, Zimmermann B, Hampel K, Christian F, Romano D, Terhzaz S, Lee LC, Willis MJ, Morton DB, Beavo JA, Shimizu-Albergine M, Davies SA, Kolch W, Houslay MD, Baillie GS.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1533-42. doi: 10.1073/pnas.1303004110. Epub 2013 Mar 18.


A biogenic amine and a neuropeptide act identically: tyramine signals through calcium in Drosophila tubule stellate cells.

Cabrero P, Richmond L, Nitabach M, Davies SA, Dow JA.

Proc Biol Sci. 2013 Feb 27;280(1757):20122943. doi: 10.1098/rspb.2012.2943. Print 2013 Apr 22.


Receptor-type guanylyl cyclase Gyc76C is required for development of the Drosophila embryonic somatic muscle.

Patel U, Davies SA, Myat MM.

Biol Open. 2012 Jun 15;1(6):507-15. doi: 10.1242/bio.2012943. Epub 2012 Apr 16.


Consolidated and labile odor memory are separately encoded within the Drosophila brain.

Scheunemann L, Jost E, Richlitzki A, Day JP, Sebastian S, Thum AS, Efetova M, Davies SA, Schwärzel M.

J Neurosci. 2012 Nov 28;32(48):17163-71. doi: 10.1523/JNEUROSCI.3286-12.2012.


Functional correlates of positional and gender-specific renal asymmetry in Drosophila.

Chintapalli VR, Terhzaz S, Wang J, Al Bratty M, Watson DG, Herzyk P, Davies SA, Dow JA.

PLoS One. 2012;7(4):e32577. doi: 10.1371/journal.pone.0032577. Epub 2012 Apr 4.


The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila.

Kanao T, Sawada T, Davies SA, Ichinose H, Hasegawa K, Takahashi R, Hattori N, Imai Y.

PLoS One. 2012;7(2):e30958. doi: 10.1371/journal.pone.0030958. Epub 2012 Feb 29.


Immune and stress response 'cross-talk' in the Drosophila Malpighian tubule.

Davies SA, Overend G, Sebastian S, Cundall M, Cabrero P, Dow JA, Terhzaz S.

J Insect Physiol. 2012 Apr;58(4):488-97. doi: 10.1016/j.jinsphys.2012.01.008. Epub 2012 Jan 28. Review.


Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor.

Terhzaz S, Cabrero P, Robben JH, Radford JC, Hudson BD, Milligan G, Dow JA, Davies SA.

PLoS One. 2012;7(1):e29897. doi: 10.1371/journal.pone.0029897. Epub 2012 Jan 11.


The receptor guanylate cyclase Gyc76C and a peptide ligand, NPLP1-VQQ, modulate the innate immune IMD pathway in response to salt stress.

Overend G, Cabrero P, Guo AX, Sebastian S, Cundall M, Armstrong H, Mertens I, Schoofs L, Dow JA, Davies SA.

Peptides. 2012 Mar;34(1):209-18. doi: 10.1016/j.peptides.2011.08.019. Epub 2011 Aug 27.


Behavioral responses to hypoxia in Drosophila larvae are mediated by atypical soluble guanylyl cyclases.

Vermehren-Schmaedick A, Ainsley JA, Johnson WA, Davies SA, Morton DB.

Genetics. 2010 Sep;186(1):183-96. doi: 10.1534/genetics.110.118166. Epub 2010 Jun 30.


Cell-specific inositol 1,4,5 trisphosphate 3-kinase mediates epithelial cell apoptosis in response to oxidative stress in Drosophila.

Terhzaz S, Finlayson AJ, Stirrat L, Yang J, Tricoire H, Woods DJ, Dow JA, Davies SA.

Cell Signal. 2010 May;22(5):737-48. doi: 10.1016/j.cellsig.2009.12.009. Epub 2010 Jan 11.


Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants.

Terhzaz S, Cabrero P, Chintapalli VR, Davies SA, Dow JA.

Physiol Genomics. 2010 Mar 3;41(1):33-41. doi: 10.1152/physiolgenomics.00147.2009. Epub 2009 Dec 15.


Organellar calcium signalling mechanisms in Drosophila epithelial function.

Davies SA, Terhzaz S.

J Exp Biol. 2009 Feb;212(Pt 3):387-400. doi: 10.1242/jeb.024513. Review.


Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress.

Stergiopoulos K, Cabrero P, Davies SA, Dow JA.

Physiol Genomics. 2009 Mar 3;37(1):1-11. doi: 10.1152/physiolgenomics.90360.2008. Epub 2008 Nov 18.


Modulation of epithelial innate immunity by autocrine production of nitric oxide.

Davies SA, Dow JA.

Gen Comp Endocrinol. 2009 May 15;162(1):113-21. doi: 10.1016/j.ygcen.2008.09.012. Epub 2008 Oct 10. Review.


Identification of two partners from the bacterial Kef exchanger family for the apical plasma membrane V-ATPase of Metazoa.

Day JP, Wan S, Allan AK, Kean L, Davies SA, Gray JV, Dow JA.

J Cell Sci. 2008 Aug 1;121(Pt 15):2612-9. doi: 10.1242/jcs.033084. Epub 2008 Jul 15.


Regulation of a Drosophila melanogaster cGMP-specific phosphodiesterase by prenylation and interaction with a prenyl-binding protein.

Day JP, Cleghon V, Houslay MD, Davies SA.

Biochem J. 2008 Sep 15;414(3):363-74. doi: 10.1042/BJ20080560.


A new role for a classical gene: white transports cyclic GMP.

Evans JM, Day JP, Cabrero P, Dow JA, Davies SA.

J Exp Biol. 2008 Mar;211(Pt 6):890-9. doi: 10.1242/jeb.014837.


cGMP signalling in a transporting epithelium.

Davies SA, Day JP.

Biochem Soc Trans. 2006 Aug;34(Pt 4):512-4. Review.


The SzA mutations of the B subunit of the Drosophila vacuolar H+ ATPase identify conserved residues essential for function in fly and yeast.

Du J, Kean L, Allan AK, Southall TD, Davies SA, McInerny CJ, Dow JA.

J Cell Sci. 2006 Jun 15;119(Pt 12):2542-51. Epub 2006 May 30.


Differential gel electrophoresis and transgenic mitochondrial calcium reporters demonstrate spatiotemporal filtering in calcium control of mitochondria.

Terhzaz S, Southall TD, Lilley KS, Kean L, Allan AK, Davies SA, Dow JA.

J Biol Chem. 2006 Jul 7;281(27):18849-58. Epub 2006 May 2.


Novel subcellular locations and functions for secretory pathway Ca2+/Mn2+-ATPases.

Southall TD, Terhzaz S, Cabrero P, Chintapalli VR, Evans JM, Dow JA, Davies SA.

Physiol Genomics. 2006 Jun 16;26(1):35-45. Epub 2006 Apr 11.


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