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Items: 1 to 50 of 287

1.

Simulated, biorelevant, clinically relevant or physiologically relevant dissolution media: The hidden role of bicarbonate buffer.

Amaral Silva D, Al-Gousous J, Davies NM, Bou Chacra N, Webster GK, Lipka E, Amidon G, Löbenberg R.

Eur J Pharm Biopharm. 2019 Jun 10. pii: S0939-6411(19)30480-1. doi: 10.1016/j.ejpb.2019.06.006. [Epub ahead of print] Review.

PMID:
31195131
2.

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

Carter AR, Gill D, Davies NM, Taylor AE, Tillmann T, Vaucher J, Wootton RE, Munafò MR, Hemani G, Malik R, Seshadri S, Woo D, Burgess S, Davey Smith G, Holmes MV, Tzoulaki I, Howe LD, Dehghan A.

BMJ. 2019 May 22;365:l1855. doi: 10.1136/bmj.l1855.

3.

Schizophrenia risk and reproductive success: a Mendelian randomization study.

Lawn RB, Sallis HM, Taylor AE, Wootton RE, Smith GD, Davies NM, Hemani G, Fraser A, Penton-Voak IS, Munafò MR.

R Soc Open Sci. 2019 Mar 6;6(3):181049. doi: 10.1098/rsos.181049. eCollection 2019 Mar.

4.

Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

Lawson DJ, Davies NM, Haworth S, Ashraf B, Howe L, Crawford A, Hemani G, Davey Smith G, Timpson NJ.

Hum Genet. 2019 Apr 27. doi: 10.1007/s00439-019-02014-8. [Epub ahead of print]

PMID:
31030318
5.

Testing the validity of value-added measures of educational progress with genetic data.

Morris TT, Davies NM, Dorling D, Richmond RC, Smith GD.

Br Educ Res J. 2018 Oct;44(5):725-747. doi: 10.1002/berj.3466. Epub 2018 Sep 9.

6.

Selection Bias When Estimating Average Treatment Effects Using One-sample Instrumental Variable Analysis.

Hughes RA, Davies NM, Davey Smith G, Tilling K.

Epidemiology. 2019 May;30(3):350-357. doi: 10.1097/EDE.0000000000000972.

PMID:
30896457
7.

Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization.

Millard LAC, Davies NM, Tilling K, Gaunt TR, Davey Smith G.

PLoS Genet. 2019 Feb 1;15(2):e1007951. doi: 10.1371/journal.pgen.1007951. eCollection 2019 Feb.

8.

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.

de Vries PS, Sabater-Lleal M, Huffman JE, Marten J, Song C, Pankratz N, Bartz TM, de Haan HG, Delgado GE, Eicher JD, Martinez-Perez A, Ward-Caviness CK, Brody JA, Chen MH, de Maat MPM, Frånberg M, Gill D, Kleber ME, Rivadeneira F, Soria JM, Tang W, Tofler GH, Uitterlinden AG, van Hylckama Vlieg A, Seshadri S, Boerwinkle E, Davies NM, Giese AK, Ikram MK, Kittner SJ, McKnight B, Psaty BM, Reiner AP, Sargurupremraj M, Taylor KD; INVENT Consortium; MEGASTROKE Consortium of the International Stroke Genetics Consortium, Fornage M, Hamsten A, März W, Rosendaal FR, Souto JC, Dehghan A, Johnson AD, Morrison AC, O'Donnell CJ, Smith NL.

Blood. 2019 Feb 28;133(9):967-977. doi: 10.1182/blood-2018-05-849240. Epub 2019 Jan 14.

PMID:
30642921
9.

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Sabater-Lleal M, Huffman JE, de Vries PS, Marten J, Mastrangelo MA, Song C, Pankratz N, Ward-Caviness CK, Yanek LR, Trompet S, Delgado GE, Guo X, Bartz TM, Martinez-Perez A, Germain M, de Haan HG, Ozel AB, Polasek O, Smith AV, Eicher JD, Reiner AP, Tang W, Davies NM, Stott DJ, Rotter JI, Tofler GH, Boerwinkle E, de Maat MPM, Kleber ME, Welsh P, Brody JA, Chen MH, Vaidya D, Soria JM, Suchon P, van Hylckama Vlieg A, Desch KC, Kolcic I, Joshi PK, Launer LJ, Harris TB, Campbell H, Rudan I, Becker DM, Li JZ, Rivadeneira F, Uitterlinden AG, Hofman A, Franco OH, Cushman M, Psaty BM, Morange PE, McKnight B, Chong MR, Fernandez-Cadenas I, Rosand J, Lindgren A; INVENT Consortium; MEGASTROKE Consortium of the International Stroke Genetics Consortium (ISGC), Gudnason V, Wilson JF, Hayward C, Ginsburg D, Fornage M, Rosendaal FR, Souto JC, Becker LC, Jenny NS, März W, Jukema JW, Dehghan A, Trégouët DA, Morrison AC, Johnson AD, O'Donnell CJ, Strachan DP, Lowenstein CJ, Smith NL.

Circulation. 2019 Jan 29;139(5):620-635. doi: 10.1161/CIRCULATIONAHA.118.034532.

10.

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis.

Hartwig FP, Davies NM, Horta BL, Ahluwalia TS, Bisgaard H, Bønnelykke K, Caspi A, Moffitt TE, Poulton R, Sajjad A, Tiemeier HW, Dalmau-Bueno A, Guxens M, Bustamante M, Santa-Marina L, Parker N, Paus T, Pausova Z, Lauritzen L, Schnurr TM, Michaelsen KF, Hansen T, Oddy W, Pennell CE, Warrington NM, Davey Smith G, Victora CG.

Int J Epidemiol. 2019 Feb 1;48(1):45-57. doi: 10.1093/ije/dyy273.

11.

The Antioxidant Activity of Recombinant Rat Hepatic Fatty Acid Binding Protein T94A Variant.

Le T, Gong Y, Davies NM, Lillico R, Lakowski T, Roberts MS, Burczynski FJ.

J Pharm Pharm Sci. 2018;21(1s):309s-324s. doi: 10.18433/jpps30246.

12.

The Causal Effects of Education on Health Outcomes in the UK Biobank.

Davies NM, Dickson M, Davey Smith G, van den Berg GJ, Windmeijer F.

Nat Hum Behav. 2018 Feb;2(2):117-125. doi: 10.1038/s41562-017-0279-y. Epub 2018 Jan 29. No abstract available.

13.

Application of in Silico Tools in Clinical Practice using Ketoconazole as a Model Drug.

Silva DA, Duque MD, Davies NM, Löbenberg R, Ferraz HG.

J Pharm Pharm Sci. 2018;21(1s):242s-253s. doi: 10.18433/jpps30227.

14.
15.

Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study.

Wootton RE, Lawn RB, Millard LAC, Davies NM, Taylor AE, Munafò MR, Timpson NJ, Davis OSP, Davey Smith G, Haworth CMA.

BMJ. 2018 Sep 25;362:k3788. doi: 10.1136/bmj.k3788.

16.

DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways.

Maayah ZH, Zhang T, Forrest ML, Alrushaid S, Doschak MR, Davies NM, El-Kadi AOS.

Pharmaceutics. 2018 Sep 4;10(3). pii: E144. doi: 10.3390/pharmaceutics10030144.

17.

Correction to: Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative.

Alrushaid S, Zhao Y, Sayre CL, Maayah ZH, Forrest ML, Senadheera SN, Chaboyer K, Anderson HD, El-Kadi AOS, Davies NM.

Drug Deliv Transl Res. 2018 Oct;8(5):1592. doi: 10.1007/s13346-018-0569-6.

PMID:
30073575
18.

Effects of low-level laser therapy on bone healing and signs of pain in dogs following tibial plateau leveling osteotomy.

Kennedy KC, Martinez SA, Martinez SE, Tucker RL, Davies NM.

Am J Vet Res. 2018 Aug;79(8):893-904. doi: 10.2460/ajvr.79.8.893.

PMID:
30058855
19.

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians.

Davies NM, Holmes MV, Davey Smith G.

BMJ. 2018 Jul 12;362:k601. doi: 10.1136/bmj.k601. No abstract available.

20.

Bias in Mendelian randomization due to assortative mating.

Hartwig FP, Davies NM, Davey Smith G.

Genet Epidemiol. 2018 Oct;42(7):608-620. doi: 10.1002/gepi.22138. Epub 2018 Jul 3.

21.

Education and myopia: assessing the direction of causality by mendelian randomisation.

Mountjoy E, Davies NM, Plotnikov D, Smith GD, Rodriguez S, Williams CE, Guggenheim JA, Atan D.

BMJ. 2018 Jun 6;361:k2022. doi: 10.1136/bmj.k2022. Erratum in: BMJ. 2018 Jul 4;362:k2932.

22.
23.

Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children.

Taylor AE, Jones HJ, Sallis H, Euesden J, Stergiakouli E, Davies NM, Zammit S, Lawlor DA, Munafò MR, Davey Smith G, Tilling K.

Int J Epidemiol. 2018 Aug 1;47(4):1207-1216. doi: 10.1093/ije/dyy060.

24.

Response to: Long-term smoking cessation: from general practice to public health.

Taylor GMJ, Davies NM.

Int J Epidemiol. 2018 Aug 1;47(4):1356. doi: 10.1093/ije/dyy084. No abstract available.

PMID:
29746641
25.

Pharmaceutical Characterization of MyoNovin, a Novel Skeletal Muscle Regenerator: in silico, in vitro and in vivo Studies.

Alrushaid S, Davies NM, Anderson JE, Le T, Yáñez JA, Maayah ZH, El-Kadi AOS, Rachid O, Sayre CL, Löbenberg R, Burczynski FJ.

J Pharm Pharm Sci. 2018;21(1s):29683. doi: 10.18433/J3MS8H.

PMID:
29702047
26.

Are Excipients Inert? Phenytoin Pharmaceutical Investigations with New Incompatibility Insights.

Amaral Silva D, Löbenberg R, Davies NM.

J Pharm Pharm Sci. 2018;21(1s):29745. doi: 10.18433/jpps29745.

PMID:
29702046
27.

The effects of prescribing varenicline on two-year health outcomes: an observational cohort study using electronic medical records.

Davies NM, Taylor GMJ, Taylor AE, Jones T, Martin RM, Munafò MR, Windmeijer F, Thomas KH.

Addiction. 2018 Jun;113(6):1105-1116. doi: 10.1111/add.14146. Epub 2018 Feb 20.

28.

Pharmacokinetics and Drug Metabolism in Canada: The Current Landscape-A Summary of This Indispensable Special Issue.

Davies NM, Wasan KM.

Pharmaceutics. 2018 Jan 16;10(1). pii: E13. doi: 10.3390/pharmaceutics10010013.

29.

An epigenome-wide association study meta-analysis of educational attainment.

Karlsson Linnér R, Marioni RE, Rietveld CA, Simpkin AJ, Davies NM, Watanabe K, Armstrong NJ, Auro K, Baumbach C, Bonder MJ, Buchwald J, Fiorito G, Ismail K, Iurato S, Joensuu A, Karell P, Kasela S, Lahti J, McRae AF, Mandaviya PR, Seppälä I, Wang Y, Baglietto L, Binder EB, Harris SE, Hodge AM, Horvath S, Hurme M, Johannesson M, Latvala A, Mather KA, Medland SE, Metspalu A, Milani L, Milne RL, Pattie A, Pedersen NL, Peters A, Polidoro S, Räikkönen K, Severi G, Starr JM, Stolk L, Waldenberger M, Eriksson JG, Esko T, Franke L, Gieger C, Giles GG, Hägg S, Jousilahti P, Kaprio J, Kähönen M, Lehtimäki T, Martin NG, van Meurs JBC, Ollikainen M, Perola M, Posthuma D, Raitakari OT, Sachdev PS, Taskesen E, Uitterlinden AG, Vineis P, Wijmenga C, Wright MJ, Relton C, Davey Smith G, Deary IJ, Koellinger PD, Benjamin DJ.

Mol Psychiatry. 2017 Dec;22(12):1680-1690. doi: 10.1038/mp.2017.210. Epub 2017 Oct 31.

30.

Software Application Profile: PHESANT: a tool for performing automated phenome scans in UK Biobank.

Millard LAC, Davies NM, Gaunt TR, Davey Smith G, Tilling K.

Int J Epidemiol. 2017 Oct 5. doi: 10.1093/ije/dyx204. [Epub ahead of print]

31.

Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities.

Walker VM, Davey Smith G, Davies NM, Martin RM.

Int J Epidemiol. 2017 Dec 1;46(6):2078-2089. doi: 10.1093/ije/dyx207.

32.

The effectiveness of varenicline versus nicotine replacement therapy on long-term smoking cessation in primary care: a prospective cohort study of electronic medical records.

Taylor GMJ, Taylor AE, Thomas KH, Jones T, Martin RM, Munafò MR, Windmeijer F, Davies NM.

Int J Epidemiol. 2017 Dec 1;46(6):1948-1957. doi: 10.1093/ije/dyx109.

33.

Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids.

Novaes JT, Lillico R, Sayre CL, Nagabushnam K, Majeed M, Chen Y, Ho EA, Oliveira ALP, Martinez SE, Alrushaid S, Davies NM, Lakowski TM.

Pharmaceutics. 2017 Oct 12;9(4). pii: E45. doi: 10.3390/pharmaceutics9040045.

34.

Pharmacokinetic and Toxicodynamic Characterization of a Novel Doxorubicin Derivative.

Alrushaid S, Sayre CL, Yáñez JA, Forrest ML, Senadheera SN, Burczynski FJ, Löbenberg R, Davies NM.

Pharmaceutics. 2017 Sep 13;9(3). pii: E35. doi: 10.3390/pharmaceutics9030035.

35.

Pharmacokinetic Analysis of an Oral Multicomponent Joint Dietary Supplement (Phycox®) in Dogs.

Martinez SE, Lillico R, Lakowski TM, Martinez SA, Davies NM.

Pharmaceutics. 2017 Aug 18;9(3). pii: E30. doi: 10.3390/pharmaceutics9030030.

36.

Stereospecific pharmacokinetic characterization of liquiritigenin in the rat.

Alrushaid S, Davies NM, Martinez SE, Sayre CL.

Res Pharm Sci. 2017 Jun;12(3):176-186. doi: 10.4103/1735-5362.207197.

37.

Comments on "Effects of Obesity and Leptin Deficiency on Morphine Pharmacokinetics in a Mouse Model" by Dalesio et al, Anesth Analg. 2016;123: 1611-1617.

Brocks DR, Davies NM.

Anesth Analg. 2017 Jul;125(1):361. doi: 10.1213/ANE.0000000000002178. No abstract available.

PMID:
28609335
38.

Power calculator for instrumental variable analysis in pharmacoepidemiology.

Walker VM, Davies NM, Windmeijer F, Burgess S, Martin RM.

Int J Epidemiol. 2017 Oct 1;46(5):1627-1632. doi: 10.1093/ije/dyx090.

39.

Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative.

Alrushaid S, Zhao Y, Sayre CL, Maayah ZH, Forrest ML, Senadheera SN, Chaboyer K, Anderson HD, El-Kadi AOS, Davies NM.

Drug Deliv Transl Res. 2017 Aug;7(4):582-597. doi: 10.1007/s13346-017-0379-2. Erratum in: Drug Deliv Transl Res. 2018 Oct;8(5):1592.

40.

How to compare instrumental variable and conventional regression analyses using negative controls and bias plots.

Davies NM, Thomas KH, Taylor AE, Taylor GMJ, Martin RM, Munafò MR, Windmeijer F.

Int J Epidemiol. 2017 Dec 1;46(6):2067-2077. doi: 10.1093/ije/dyx014.

41.

Correction: Breastfeeding effects on DNA methylation in the offspring: A systematic literature review.

Hartwig FP, Loret de Mola C, Davies NM, Victora CG, Relton CL.

PLoS One. 2017 Apr 6;12(4):e0175604. doi: 10.1371/journal.pone.0175604. eCollection 2017.

42.

Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique.

Hartwig FP, Davies NM, Hemani G, Davey Smith G.

Int J Epidemiol. 2016 Dec 1;45(6):1717-1726. doi: 10.1093/ije/dyx028. No abstract available.

43.

Breastfeeding effects on DNA methylation in the offspring: A systematic literature review.

Hartwig FP, Loret de Mola C, Davies NM, Victora CG, Relton CL.

PLoS One. 2017 Mar 3;12(3):e0173070. doi: 10.1371/journal.pone.0173070. eCollection 2017. Review. Erratum in: PLoS One. 2017 Apr 6;12 (4):e0175604.

44.

Simultaneous quantification of reparixin and paclitaxel in plasma and urine using ultra performance liquid chromatography-tandem mass spectroscopy (UHPLC-MS/MS): Application to a preclinical pharmacokinetic study in rats.

Malhi S, Stesco N, Alrushaid S, Lakowski TM, Davies NM, Gu X.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 1;1046:165-171. doi: 10.1016/j.jchromb.2016.12.015. Epub 2017 Feb 3.

PMID:
28187377
45.

Disparate Effects of Stilbenoid Polyphenols on Hypertrophic Cardiomyocytes In Vitro vs. in the Spontaneously Hypertensive Heart Failure Rat.

Akinwumi BC, Raj P, Lee DI, Acosta C, Yu L, Thomas SM, Nagabhushanam K, Majeed M, Davies NM, Netticadan T, Anderson HD.

Molecules. 2017 Feb 1;22(2). pii: E204. doi: 10.3390/molecules22020204.

47.

Pharmacological characterization of liquiritigenin, a chiral flavonoid in licorice.

Alrushaid S, Davies NM, Martinez SE, Sayre CL.

Res Pharm Sci. 2016 Oct;11(5):355-365.

48.

Influences on antidepressant prescribing trends in the UK: 1995-2011.

Mars B, Heron J, Kessler D, Davies NM, Martin RM, Thomas KH, Gunnell D.

Soc Psychiatry Psychiatr Epidemiol. 2017 Feb;52(2):193-200. doi: 10.1007/s00127-016-1306-4. Epub 2016 Nov 24.

49.

Estimating Marginal Healthcare Costs Using Genetic Variants as Instrumental Variables: Mendelian Randomization in Economic Evaluation.

Dixon P, Davey Smith G, von Hinke S, Davies NM, Hollingworth W.

Pharmacoeconomics. 2016 Nov;34(11):1075-1086.

50.

The Food and Drug Administration and varenicline: should risk communication be improved?

Davies NM, Thomas KH.

Addiction. 2017 Apr;112(4):555-558. doi: 10.1111/add.13592. Epub 2016 Oct 18. No abstract available.

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