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Items: 11


Monogamy promotes altruistic sterility in insect societies.

Davies NG, Gardner A.

R Soc Open Sci. 2018 May 9;5(5):172190. doi: 10.1098/rsos.172190. eCollection 2018 May.


Family matters.

Davies NG.

Nat Ecol Evol. 2018 Jun;2(6):927-928. doi: 10.1038/s41559-018-0541-3. No abstract available.


Use of mathematical modelling to assess the impact of vaccines on antibiotic resistance.

Atkins KE, Lafferty EI, Deeny SR, Davies NG, Robotham JV, Jit M.

Lancet Infect Dis. 2018 Jun;18(6):e204-e213. doi: 10.1016/S1473-3099(17)30478-4. Epub 2017 Nov 13. Review.


Application of Off-Rate Screening in the Identification of Novel Pan-Isoform Inhibitors of Pyruvate Dehydrogenase Kinase.

Brough PA, Baker L, Bedford S, Brown K, Chavda S, Chell V, D'Alessandro J, Davies NG, Davis B, Le Strat L, Macias AT, Maddox D, Mahon PC, Massey AJ, Matassova N, McKenna S, Meissner JW, Moore JD, Murray JB, Northfield CJ, Parry C, Parsons R, Roughley SD, Shaw T, Simmonite H, Stokes S, Surgenor A, Stefaniak E, Robertson A, Wang Y, Webb P, Whitehead N, Wood M.

J Med Chem. 2017 Mar 23;60(6):2271-2286. doi: 10.1021/acs.jmedchem.6b01478. Epub 2017 Feb 15.


The ecology of sex explains patterns of helping in arthropod societies.

Davies NG, Ross L, Gardner A.

Ecol Lett. 2016 Aug;19(8):862-72. doi: 10.1111/ele.12621. Epub 2016 Jun 2.


Evolution of paternal care in diploid and haplodiploid populations.

Davies NG, Gardner A.

J Evol Biol. 2014 Jun;27(6):1012-9. doi: 10.1111/jeb.12375. Epub 2014 Apr 28.


Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization.

Davies NG, Browne H, Davis B, Drysdale MJ, Foloppe N, Geoffrey S, Gibbons B, Hart T, Hubbard R, Jensen MR, Mansell H, Massey A, Matassova N, Moore JD, Murray J, Pratt R, Ray S, Robertson A, Roughley SD, Schoepfer J, Scriven K, Simmonite H, Stokes S, Surgenor A, Webb P, Wood M, Wright L, Brough P.

Bioorg Med Chem. 2012 Nov 15;20(22):6770-89. doi: 10.1016/j.bmc.2012.08.050. Epub 2012 Sep 4.


Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone.

Brough PA, Barril X, Borgognoni J, Chene P, Davies NG, Davis B, Drysdale MJ, Dymock B, Eccles SA, Garcia-Echeverria C, Fromont C, Hayes A, Hubbard RE, Jordan AM, Jensen MR, Massey A, Merrett A, Padfield A, Parsons R, Radimerski T, Raynaud FI, Robertson A, Roughley SD, Schoepfer J, Simmonite H, Sharp SY, Surgenor A, Valenti M, Walls S, Webb P, Wood M, Workman P, Wright L.

J Med Chem. 2009 Aug 13;52(15):4794-809. doi: 10.1021/jm900357y.


A complication of the 'atraumatic inserter' of the Tracoe experc percutaneous dilation tracheostomy set.

Saxena N, Greenway I, Harding LJ, Davies NG.

Anaesthesia. 2008 Dec;63(12):1377-9. doi: 10.1111/j.1365-2044.2008.05771.x. No abstract available.


4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.

Brough PA, Aherne W, Barril X, Borgognoni J, Boxall K, Cansfield JE, Cheung KM, Collins I, Davies NG, Drysdale MJ, Dymock B, Eccles SA, Finch H, Fink A, Hayes A, Howes R, Hubbard RE, James K, Jordan AM, Lockie A, Martins V, Massey A, Matthews TP, McDonald E, Northfield CJ, Pearl LH, Prodromou C, Ray S, Raynaud FI, Roughley SD, Sharp SY, Surgenor A, Walmsley DL, Webb P, Wood M, Workman P, Wright L.

J Med Chem. 2008 Jan 24;51(2):196-218. Epub 2007 Nov 20.


Species variations in cutaneous alcohol dehydrogenases and aldehyde dehydrogenases may impact on toxicological assessments of alcohols and aldehydes.

Cheung C, Davies NG, Hoog JO, Hotchkiss SA, Smith Pease CK.

Toxicology. 2003 Mar 3;184(2-3):97-112.


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