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Items: 30

1.

Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease.

Pearsall RS, Davies MV, Cannell M, Li J, Widrick J, Mulivor AW, Wallner S, Troy ME, Spaits M, Liharska K, Sako D, Castonguay R, Keates S, Grinberg AV, Suragani RNVS, Kumar R.

Sci Rep. 2019 Aug 6;9(1):11392. doi: 10.1038/s41598-019-47818-w.

2.

Follistatin-288-Fc Fusion Protein Promotes Localized Growth of Skeletal Muscle.

Castonguay R, Lachey J, Wallner S, Strand J, Liharska K, Watanabe AE, Cannell M, Davies MV, Sako D, Troy ME, Krishnan L, Mulivor AW, Li H, Keates S, Alexander MJ, Pearsall RS, Kumar R.

J Pharmacol Exp Ther. 2019 Mar;368(3):435-445. doi: 10.1124/jpet.118.252304. Epub 2018 Dec 18.

PMID:
30563942
3.

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis.

Suragani RN, Cadena SM, Cawley SM, Sako D, Mitchell D, Li R, Davies MV, Alexander MJ, Devine M, Loveday KS, Underwood KW, Grinberg AV, Quisel JD, Chopra R, Pearsall RS, Seehra J, Kumar R.

Nat Med. 2014 Apr;20(4):408-14. doi: 10.1038/nm.3512. Epub 2014 Mar 23.

PMID:
24658078
4.

Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.

Sako D, Grinberg AV, Liu J, Davies MV, Castonguay R, Maniatis S, Andreucci AJ, Pobre EG, Tomkinson KN, Monnell TE, Ucran JA, Martinez-Hackert E, Pearsall RS, Underwood KW, Seehra J, Kumar R.

J Biol Chem. 2010 Jul 2;285(27):21037-48. doi: 10.1074/jbc.M110.114959. Epub 2010 Apr 12.

5.

A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys.

Lotinun S, Pearsall RS, Davies MV, Marvell TH, Monnell TE, Ucran J, Fajardo RJ, Kumar R, Underwood KW, Seehra J, Bouxsein ML, Baron R.

Bone. 2010 Apr;46(4):1082-8. doi: 10.1016/j.bone.2010.01.370. Epub 2010 Jan 18.

PMID:
20080223
6.

Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis).

Fajardo RJ, Manoharan RK, Pearsall RS, Davies MV, Marvell T, Monnell TE, Ucran JA, Pearsall AE, Khanzode D, Kumar R, Underwood KW, Roberts B, Seehra J, Bouxsein ML.

Bone. 2010 Jan;46(1):64-71. doi: 10.1016/j.bone.2009.09.018. Epub 2009 Sep 23.

PMID:
19781677
7.

Regulation of muscle growth by multiple ligands signaling through activin type II receptors.

Lee SJ, Reed LA, Davies MV, Girgenrath S, Goad ME, Tomkinson KN, Wright JF, Barker C, Ehrmantraut G, Holmstrom J, Trowell B, Gertz B, Jiang MS, Sebald SM, Matzuk M, Li E, Liang LF, Quattlebaum E, Stotish RL, Wolfman NM.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18117-22. Epub 2005 Dec 5.

8.

The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis.

Scheuner D, Gromeier M, Davies MV, Dorner AJ, Song B, Patel RV, Wimmer EJ, McLendon RE, Kaufman RJ.

Virology. 2003 Dec 20;317(2):263-74.

9.

Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases.

Wolfman NM, McPherron AC, Pappano WN, Davies MV, Song K, Tomkinson KN, Wright JF, Zhao L, Sebald SM, Greenspan DS, Lee SJ.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15842-6. Epub 2003 Dec 11.

10.

The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum.

Hill JJ, Davies MV, Pearson AA, Wang JH, Hewick RM, Wolfman NM, Qiu Y.

J Biol Chem. 2002 Oct 25;277(43):40735-41. Epub 2002 Aug 22.

11.

Induction of cachexia in mice by systemically administered myostatin.

Zimmers TA, Davies MV, Koniaris LG, Haynes P, Esquela AF, Tomkinson KN, McPherron AC, Wolfman NM, Lee SJ.

Science. 2002 May 24;296(5572):1486-8.

12.

GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding.

Thies RS, Chen T, Davies MV, Tomkinson KN, Pearson AA, Shakey QA, Wolfman NM.

Growth Factors. 2001;18(4):251-9.

PMID:
11519824
13.
15.

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR.

Park H, Davies MV, Langland JO, Chang HW, Nam YS, Tartaglia J, Paoletti E, Jacobs BL, Kaufman RJ, Venkatesan S.

Proc Natl Acad Sci U S A. 1994 May 24;91(11):4713-7.

16.

Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis.

Murtha-Riel P, Davies MV, Scherer BJ, Choi SY, Hershey JW, Kaufman RJ.

J Biol Chem. 1993 Jun 15;268(17):12946-51.

17.

Characterization of wild-type and Ser53 mutant eukaryotic initiation factor 4E overexpression in mammalian cells.

Kaufman RJ, Murtha-Riel P, Pittman DD, Davies MV.

J Biol Chem. 1993 Jun 5;268(16):11902-9.

19.

Internal translation initiation in the design of improved expression vectors.

Davies MV, Kaufman RJ.

Curr Opin Biotechnol. 1992 Oct;3(5):512-7. Review.

PMID:
1368936
22.

Stimulation of protein synthesis in COS cells transfected with variants of the alpha-subunit of initiation factor eIF-2.

Choi SY, Scherer BJ, Schnier J, Davies MV, Kaufman RJ, Hershey JW.

J Biol Chem. 1992 Jan 5;267(1):286-93.

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26.

Complementation of adenovirus virus-associated RNA I gene deletion by expression of a mutant eukaryotic translation initiation factor.

Davies MV, Furtado M, Hershey JW, Thimmappaya B, Kaufman RJ.

Proc Natl Acad Sci U S A. 1989 Dec;86(23):9163-7.

28.

The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs.

Kaufman RJ, Davies MV, Pathak VK, Hershey JW.

Mol Cell Biol. 1989 Mar;9(3):946-58.

29.

Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells.

Kaufman RJ, Wasley LC, Davies MV, Wise RJ, Israel DI, Dorner AJ.

Mol Cell Biol. 1989 Mar;9(3):1233-42.

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