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The Landscape of Early Clinical Gene Therapies outside of Oncology.

Rittié L, Athanasopoulos T, Calero-Garcia M, Davies ML, Dow DJ, Howe SJ, Morrison A, Ricciardelli I, Saudemont A, Jespers L, Clay TM.

Mol Ther. 2019 Sep 6. pii: S1525-0016(19)30403-4. doi: 10.1016/j.ymthe.2019.09.002. [Epub ahead of print] Review.


Scarlet fever changes its spots.

Brouwer S, Lacey JA, You Y, Davies MR, Walker MJ.

Lancet Infect Dis. 2019 Sep 10. pii: S1473-3099(19)30494-3. doi: 10.1016/S1473-3099(19)30494-3. [Epub ahead of print] No abstract available.


Call center performance affects patient perceptions of access and satisfaction.

Griffith KN, Li D, Davies ML, Pizer SD, Prentice JC.

Am J Manag Care. 2019 Sep 1;25(9):e282-e287.


Model-based super-resolution reconstruction of T2 maps.

Bano W, Piredda GF, Davies M, Marshall I, Golbabaee M, Meuli R, Kober T, Thiran JP, Hilbert T.

Magn Reson Med. 2019 Sep 13. doi: 10.1002/mrm.27981. [Epub ahead of print]


The effect of computerised tomography on operative planning in posterior malleolus ankle fractures.

Sheikh HQ, Mills EJ, McGregor-Riley JC, Chadwick C, Davies MB.

Foot Ankle Surg. 2019 Aug 28. pii: S1268-7731(19)30139-0. doi: 10.1016/j.fas.2019.08.007. [Epub ahead of print]


Acute and Long-term Adverse Events Associated With Checkpoint Blockade.

Davies M.

Semin Oncol Nurs. 2019 Sep 9:150926. doi: 10.1016/j.soncn.2019.08.005. [Epub ahead of print] Review.


Whey proteins: targets of oxidation, or mediators of redox protection.

Giblin L, Süha Yalçın A, Biçim G, Krämer AC, Chen Z, Callanan MJ, Arranz E, Davies MJ.

Free Radic Res. 2019 Sep 12:1-17. doi: 10.1080/10715762.2019.1632445. [Epub ahead of print]


The Microalbuminuria Education Medication and Optimisation (MEMO) study: 4 years follow-up of multifactorial intervention in high-risk individuals with type 2 diabetes.

Crasto W, Morrison AE, Gray LJ, John E, Jarvis J, Brela J, Khunti K, Troughton J, Lawrence IG, McNally PG, Davies MJ.

Diabet Med. 2019 Sep 10. doi: 10.1111/dme.14134. [Epub ahead of print]


Prevalence of and Risk Factors for Total Hip and Knee Replacement in Retired National Football League Athletes.

Davies MAM, Kerr ZY, DeFreese JD, Arden NK, Marshall SW, Guskiewicz KM, Padua DA, Pietrosimone B.

Am J Sports Med. 2019 Sep 9:363546519870804. doi: 10.1177/0363546519870804. [Epub ahead of print]


Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-d-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings.

Zacharias T, Flouda K, Jepps TA, Gammelgaard B, Schiesser CH, Davies MJ.

Biochem Pharmacol. 2019 Sep 5:113631. doi: 10.1016/j.bcp.2019.113631. [Epub ahead of print]


Stem cell injections for axial back pain: a systematic review of associated risks and complications with a case illustration of diffuse hyperplastic gliosis resulting in cauda equina syndrome.

Aoun SG, Peinado Reyes V, El Ahmadieh TY, Davies M, Patel AR, Ban VS, Plitt A, El Tecle NE, Moreno JR, Raisanen J, Bagley CA.

J Neurosurg Spine. 2019 Sep 6:1-8. doi: 10.3171/2019.6.SPINE19594. [Epub ahead of print] Review.


Reduced uterine volume after induction of puberty in women with hypogonadism.

Burt E, Davies MC, Yasmin E, Cameron-Pimblett A, Mavrelos D, Talaulikar V, Conway GS.

Clin Endocrinol (Oxf). 2019 Sep 5. doi: 10.1111/cen.14092. [Epub ahead of print]


FlowSculpt: software for efficient design of inertial flow sculpting devices.

Stoecklein D, Davies M, de Rutte JM, Wu CY, Di Carlo D, Ganapathysubramanian B.

Lab Chip. 2019 Sep 4. doi: 10.1039/c9lc00658c. [Epub ahead of print]


Use of Urban Health Indicator Tools by Built Environment Policy- and Decision-Makers: a Systematic Review and Narrative Synthesis.

Pineo H, Glonti K, Rutter H, Zimmermann N, Wilkinson P, Davies M.

J Urban Health. 2019 Sep 3. doi: 10.1007/s11524-019-00378-w. [Epub ahead of print]


Increased Risk of Musculoskeletal Disorders and Mental Health Problems in Retired Professional Jockeys: A Cross-Sectional Study.

Mackinnon AL, Jackson K, Kuznik K, Turner A, Hill J, Davies MAM, Jones ME, Delmestri A, Sanchez-Santos MT, Newton J.

Int J Sports Med. 2019 Sep 3. doi: 10.1055/a-1004-5495. [Epub ahead of print] No abstract available.


The right place for Sulphonylureas today: Part of review the series: Implications of recent CVOTs in Type 2 Diabetes Mellitus.

Webb DR, Davies MJ, Jarvis J, Seidu S, Khunti K.

Diabetes Res Clin Pract. 2019 Aug 31:107836. doi: 10.1016/j.diabres.2019.107836. [Epub ahead of print] Review.


activPAL and ActiGraph Assessed Sedentary Behavior and Cardiometabolic Health Markers.

Edwardson CL, Henson J, Biddle SJH, Davies MJ, Khunti K, Maylor B, Yates T.

Med Sci Sports Exerc. 2019 Aug 30. doi: 10.1249/MSS.0000000000002138. [Epub ahead of print]


Process evaluation of the school-based Girls Active programme.

Gorely T, Harrington DM, Bodicoat DH, Davies MJ, Khunti K, Sherar LB, Tudor-Edwards R, Yates T, Edwardson CL.

BMC Public Health. 2019 Aug 29;19(1):1187. doi: 10.1186/s12889-019-7493-7.


Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan.

Fuentes-Lemus E, Mariotti M, Hägglund P, Leinisch F, Fierro A, Silva E, López-Alarcón C, Davies MJ.

Free Radic Biol Med. 2019 Aug 22;143:375-386. doi: 10.1016/j.freeradbiomed.2019.08.023. [Epub ahead of print]


Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.

AbuHammad S, Cullinane C, Martin C, Bacolas Z, Ward T, Chen H, Slater A, Ardley K, Kirby L, Chan KT, Brajanovski N, Smith LK, Rao AD, Lelliott EJ, Kleinschmidt M, Vergara IA, Papenfuss AT, Lau P, Ghosh P, Haupt S, Haupt Y, Sanij E, Poortinga G, Pearson RB, Falk H, Curtis DJ, Stupple P, Devlin M, Street I, Davies MA, McArthur GA, Sheppard KE.

Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17990-18000. doi: 10.1073/pnas.1901323116. Epub 2019 Aug 22.


A novel mitochondrial inhibitor blocks MAPK pathway and overcomes MAPK inhibitor-resistance in melanoma.

Vashisht Gopal YN, Gammon ST, Prasad R, Knighton B, Pisaneschi F, Roszik J, Feng N, Johnson S, Pramanik S, Sudderth J, Sui D, Hudgens CW, Fischer GM, Deng W, Reuben A, Peng W, Wang J, Di Francesco ME, Marszalek JR, McQuade JL, Tetzlaff MT, Piwnica-Worms D, DeBerardinis RJ, Davies MA.

Clin Cancer Res. 2019 Aug 22. pii: clincanres.0836.2019. doi: 10.1158/1078-0432.CCR-19-0836. [Epub ahead of print]


Sales reps in India push unnecessary antibiotics.

Davies M, Meesaraganda R, Stockton B.

Lancet Infect Dis. 2019 Aug 19. pii: S1473-3099(19)30444-X. doi: 10.1016/S1473-3099(19)30444-X. [Epub ahead of print] No abstract available.


Using longitudinal targeted maximum likelihood estimation in complex settings with dynamic interventions.

Schomaker M, Luque-Fernandez MA, Leroy V, Davies MA.

Stat Med. 2019 Aug 22. doi: 10.1002/sim.8340. [Epub ahead of print]


Micro-costing and a cost-consequence analysis of the 'Girls Active' programme: A cluster randomised controlled trial.

Charles JM, Harrington DM, Davies MJ, Edwardson CL, Gorely T, Bodicoat DH, Khunti K, Sherar LB, Yates T, Edwards RT.

PLoS One. 2019 Aug 16;14(8):e0221276. doi: 10.1371/journal.pone.0221276. eCollection 2019.


Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study.

Long GV, Flaherty KT, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, Garbe C, Jouary T, Hauschild A, Chiarion-Sileni V, Lebbe C, Mandalá M, Millward M, Arance A, Bondarenko I, Haanen JBAG, Hansson J, Utikal J, Ferraresi V, Mohr P, Probachai V, Schadendorf D, Nathan P, Robert C, Ribas A, Davies MA, Lane SR, Legos JJ, Mookerjee B, Grob JJ.

Ann Oncol. 2019 Aug 13. pii: mdz221. doi: 10.1093/annonc/mdz221. [Epub ahead of print] No abstract available.


Impact of Depression and Anxiety on Change to Physical Activity Following a Pragmatic Diabetes Prevention Program Within Primary Care: Pooled Analysis From Two Randomized Controlled Trials.

Yates T, Gray LJ, Henson J, Edwardson CL, Khunti K, Davies MJ.

Diabetes Care. 2019 Oct;42(10):1847-1853. doi: 10.2337/dc19-0400. Epub 2019 Aug 9.


Incidence, patterns of progression, and outcomes of preexisting and newly discovered brain metastases during treatment with anti-PD-1 in patients with metastatic melanoma.

Schvartsman G, Ma J, Bassett RL Jr, Haydu LE, Amaria RN, Hwu P, Wong MK, Hwu WJ, Diab A, Patel SP, Davies MA, Hamerschlak N, Tawbi HA, Glitza Oliva IC.

Cancer. 2019 Aug 9. doi: 10.1002/cncr.32454. [Epub ahead of print]


Increased Risk of Musculoskeletal Disorders and Mental Health Problems in Retired Professional Jockeys: A Cross-Sectional Study.

Mackinnon AL, Jackson K, Kuznik K, Turner A, Hill J, Davies MAM, Jones ME, Delmestri A, Sanchez-Santos MT, Newton J.

Int J Sports Med. 2019 Aug 7. doi: 10.1055/a-0902-8601. [Epub ahead of print]


Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease.

Pearsall RS, Davies MV, Cannell M, Li J, Widrick J, Mulivor AW, Wallner S, Troy ME, Spaits M, Liharska K, Sako D, Castonguay R, Keates S, Grinberg AV, Suragani RNVS, Kumar R.

Sci Rep. 2019 Aug 6;9(1):11392. doi: 10.1038/s41598-019-47818-w.


Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features.

Nagarajan P, Piao J, Ning J, Noordenbos LE, Curry JL, Torres-Cabala CA, Diwan AH, Ivan D, Aung PP, Ross MI, Royal RE, Wargo JA, Wang WL, Samdani R, Lazar AJ, Rashid A, Davies MA, Prieto VG, Gershenwald JE, Tetzlaff MT.

Mod Pathol. 2019 Aug 5. doi: 10.1038/s41379-019-0340-7. [Epub ahead of print]


Statins and risk of thromboembolism: A meta-regression to disentangle the efficacy-to-effectiveness gap using observational and trial evidence.

Miksza JK, Zaccardi F, Kunutsor SK, Seidu S, Davies MJ, Khunti K.

Nutr Metab Cardiovasc Dis. 2019 Oct;29(10):1023-1029. doi: 10.1016/j.numecd.2019.06.022. Epub 2019 Jul 6.


Relevance of physical function in the association of red and processed meat intake with all-cause, cardiovascular, and cancer mortality.

Argyridou S, Zaccardi F, Davies MJ, Khunti K, Yates T.

Nutr Metab Cardiovasc Dis. 2019 Jun 27. pii: S0939-4753(19)30248-0. doi: 10.1016/j.numecd.2019.06.019. [Epub ahead of print]


20-year trends in cause-specific heart failure outcomes by sex, socioeconomic status, and place of diagnosis: a population-based study.

Lawson CA, Zaccardi F, Squire I, Ling S, Davies MJ, Lam CSP, Mamas MA, Khunti K, Kadam UT.

Lancet Public Health. 2019 Aug;4(8):e406-e420. doi: 10.1016/S2468-2667(19)30108-2.


Cleansing-induced changes in skin measured by in vivo confocal raman spectroscopy.

Davies MA.

Skin Res Technol. 2019 Aug 1. doi: 10.1111/srt.12760. [Epub ahead of print]


Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma.

Peng W, Williams LJ, Xu C, Melendez B, McKenzie JA, Chen Y, Jackson HL, Voo KS, Mbofung RM, Leahey SE, Wang J, Lizee G, Tawbi HA, Davies MA, Hoos A, Smothers J, Srinivasan R, Paul EM, Yanamandra N, Hwu P.

Clin Cancer Res. 2019 Aug 1. doi: 10.1158/1078-0432.CCR-19-1259. [Epub ahead of print]


Machine learning methods in predicting chemotherapy-induced neutropenia in oncology patients using clinical data.

Coupe B, Davies M, Zhou S.

Clin Med (Lond). 2019 Jun;19(Suppl 3):89-90. doi: 10.7861/clinmedicine.19-3-s89. No abstract available.


Evaluation and refinement of the PRESTARt tool for identifying 12-14 year olds at high lifetime risk of developing type 2 diabetes compared to a clinicians assessment of risk: a cross-sectional study.

Gray LJ, Brady EM, Albaina O, Edwardson CL, Harrington D, Khunti K, Miksza J, Raposo JF, Smith E, Vazeou A, Vergara I, Weihrauch-Blüher S, Davies MJ; PRE-STARt Collaborative.

BMC Endocr Disord. 2019 Jul 25;19(1):79. doi: 10.1186/s12902-019-0410-3.


Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy).

Ascierto PA, Agarwala SS, Botti G, Budillon A, Davies MA, Dummer R, Ernstoff M, Ferrone S, Formenti S, Gajewski TF, Garbe C, Hamid O, Lo RS, Luke JJ, Michielin O, Palmieri G, Zitvogel L, Marincola FM, Masucci G, Caracò C, Thurin M, Puzanov I.

J Transl Med. 2019 Jul 22;17(1):234. doi: 10.1186/s12967-019-1979-z.


Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Davies MR, McIntyre L, Mutreja A, Lacey JA, Lees JA, Towers RJ, Duchêne S, Smeesters PR, Frost HR, Price DJ, Holden MTG, David S, Giffard PM, Worthing KA, Seale AC, Berkley JA, Harris SR, Rivera-Hernandez T, Berking O, Cork AJ, Torres RSLA, Lithgow T, Strugnell RA, Bergmann R, Nitsche-Schmitz P, Chhatwal GS, Bentley SD, Fraser JD, Moreland NJ, Carapetis JR, Steer AC, Parkhill J, Saul A, Williamson DA, Currie BJ, Tong SYC, Dougan G, Walker MJ.

Nat Genet. 2019 Aug;51(8):1295. doi: 10.1038/s41588-019-0482-z.


International Exchange Programs: Professional Development and Benefits to Oncology Nursing Practice.

Turner L, Lau V, Neeson S, Davies M.

Clin J Oncol Nurs. 2019 Aug 1;23(4):439-442. doi: 10.1188/19.CJON.439-442.


Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response.

Haragan A, Field JK, Davies MPA, Escriu C, Gruver A, Gosney JR.

Lung Cancer. 2019 Aug;134:79-84. doi: 10.1016/j.lungcan.2019.06.005. Epub 2019 Jun 5.


Activity Intensity, Volume, and Norms: Utility and Interpretation of Accelerometer Metrics.

Rowlands AV, Fairclough SJ, Yates T, Edwardson CL, Davies M, Munir F, Khunti K, Stiles VH.

Med Sci Sports Exerc. 2019 Jul 12. doi: 10.1249/MSS.0000000000002047. [Epub ahead of print]


Differential left ventricular and left atrial remodelling in heart failure with preserved ejection fraction patients with and without diabetes.

Gulsin GS, Kanagala P, Chan DCS, Cheng ASH, Athithan L, Graham-Brown MPM, Singh A, Yang J, Li Z, Khunti K, Davies MJ, Arnold JR, Squire IB, Ng LL, McCann GP.

Ther Adv Endocrinol Metab. 2019 Jul 5;10:2042018819861593. doi: 10.1177/2042018819861593. eCollection 2019.


A newly developed anesthetic based on a unique chemical core.

Cayla NS, Dagne BA, Wu Y, Lu Y, Rodriguez L, Davies DL, Gross ER, Heifets BD, Davies MF, MacIver MB, Bertaccini EJ.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15706-15715. doi: 10.1073/pnas.1822076116. Epub 2019 Jul 15.


A data-driven, meaningful, easy to interpret, standardised accelerometer outcome variable for global surveillance.

Rowlands AV, Sherar LB, Fairclough SJ, Yates T, Edwardson CL, Harrington DM, Davies MJ, Munir F, Khunti K, Stiles VH.

J Sci Med Sport. 2019 Oct;22(10):1132-1138. doi: 10.1016/j.jsams.2019.06.016. Epub 2019 Jul 1.


Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer.

Woolston A, Khan K, Spain G, Barber LJ, Griffiths B, Gonzalez-Exposito R, Hornsteiner L, Punta M, Patil Y, Newey A, Mansukhani S, Davies MN, Furness A, Sclafani F, Peckitt C, Jiménez M, Kouvelakis K, Ranftl R, Begum R, Rana I, Thomas J, Bryant A, Quezada S, Wotherspoon A, Khan N, Fotiadis N, Marafioti T, Powles T, Lise S, Calvo F, Guettler S, von Loga K, Rao S, Watkins D, Starling N, Chau I, Sadanandam A, Cunningham D, Gerlinger M.

Cancer Cell. 2019 Jul 8;36(1):35-50.e9. doi: 10.1016/j.ccell.2019.05.013.


The Challenge of Urban Heat Exposure under Climate Change: An Analysis of Cities in the Sustainable Healthy Urban Environments (SHUE) Database.

Milner J, Harpham C, Taylor J, Davies M, Le Quéré C, Haines A, Wilkinson P.

Climate (Basel). 2019 Jun 17;5(4):93. doi: 10.3390/cli5040093. Epub 2017 Dec 13.


A Comparative Analysis of Global Datasets and Initiatives for Urban Health and Sustainability.

Taylor J, Haines A, Milner J, Davies M, Wilkinson P.

Sustainability. 2019 Jun 5;10(10). doi: 10.3390/su10103636. Epub 2018 Oct 11.

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