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Items: 1 to 50 of 513

1.

Exploring patients' experience and perception of being diagnosed with bladder cancer: A mixed methods approach.

Tan WS, Teo CH, Chan D, Ang KM, Heinrich M, Feber A, Sarpong R, Williams NR, Brew-Graves C, Ng CJ, Kelly JD; DETECT II trial collaborators.

BJU Int. 2020 Jan 23. doi: 10.1111/bju.15008. [Epub ahead of print]

PMID:
31975539
2.

Identification of folate receptor α (FRα) binding oligopeptides and their evaluation for targeted virotherapy applications.

Hulin-Curtis SL, Davies JA, Nestić D, Bates EA, Baker AT, Cunliffe TG, Majhen D, Chester JD, Parker AL.

Cancer Gene Ther. 2020 Jan 6. doi: 10.1038/s41417-019-0156-0. [Epub ahead of print]

PMID:
31902944
3.

Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions.

Nobre LV, Nightingale K, Ravenhill BJ, Antrobus R, Soday L, Nichols J, Davies JA, Seirafian S, Wang EC, Davison AJ, Wilkinson GW, Stanton RJ, Huttlin EL, Weekes MP.

Elife. 2019 Dec 24;8. pii: e49894. doi: 10.7554/eLife.49894.

4.

Infrared spectroscopy of a small ion solvated by helium: OH stretching region of HeN-HOCO.

Davies JA, Besley NA, Yang S, Ellis AM.

J Chem Phys. 2019 Nov 21;151(19):194307. doi: 10.1063/1.5124137.

PMID:
31757136
5.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets.

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2019 Dec;176 Suppl 1:S1-S20. doi: 10.1111/bph.14747.

6.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors.

Alexander SPH, Cidlowski JA, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2019 Dec;176 Suppl 1:S229-S246. doi: 10.1111/bph.14750.

7.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors.

Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2019 Dec;176 Suppl 1:S21-S141. doi: 10.1111/bph.14748.

8.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors.

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2019 Dec;176 Suppl 1:S247-S296. doi: 10.1111/bph.14751.

9.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels.

Alexander SPH, Mathie A, Peters JA, Veale EL, Striessnig J, Kelly E, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2019 Dec;176 Suppl 1:S142-S228. doi: 10.1111/bph.14749.

10.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes.

Alexander SPH, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2019 Dec;176 Suppl 1:S297-S396. doi: 10.1111/bph.14752.

11.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters.

Alexander SPH, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2019 Dec;176 Suppl 1:S397-S493. doi: 10.1111/bph.14753.

12.

The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY.

Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Sharman JL, Campo B, Cavanagh DR, Alexander SPH, Davenport AP, Spedding M, Davies JA; NC-IUPHAR.

Nucleic Acids Res. 2020 Jan 8;48(D1):D1006-D1021. doi: 10.1093/nar/gkz951.

PMID:
31691834
13.

Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.

Baker AT, Mundy RM, Davies JA, Rizkallah PJ, Parker AL.

Sci Adv. 2019 Sep 4;5(9):eaax3567. doi: 10.1126/sciadv.aax3567. eCollection 2019 Sep.

14.

Inverse pharmacology: Approaches and tools for introducing druggability into engineered proteins.

Davies JA, Ireland S, Harding S, Sharman JL, Southan C, Dominguez-Monedero A.

Biotechnol Adv. 2019 Dec;37(8):107439. doi: 10.1016/j.biotechadv.2019.107439. Epub 2019 Sep 5. Review.

15.

Systemic delivery and SPECT/CT in vivo imaging of 125I-labelled oncolytic adenoviral mutants in models of pancreatic cancer.

Stella Man YK, Foster J, Carapuça E, Davies JA, Parker AL, Sosabowski J, Halldén G.

Sci Rep. 2019 Sep 6;9(1):12840. doi: 10.1038/s41598-019-49150-9.

16.

Emergence of structure in mouse embryos: Structural Entropy morphometry applied to digital models of embryonic anatomy.

Waites W, Davies JA.

J Anat. 2019 Oct;235(4):706-715. doi: 10.1111/joa.13031. Epub 2019 Jul 5.

17.
18.

Probing Elusive Cations: Infrared Spectroscopy of Protonated Acetic Acid.

Davies JA, Besley NA, Yang S, Ellis AM.

J Phys Chem Lett. 2019 May 2;10(9):2108-2112. doi: 10.1021/acs.jpclett.9b00767. Epub 2019 Apr 16.

PMID:
30973734
19.

Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions.

Baker AT, Greenshields-Watson A, Coughlan L, Davies JA, Uusi-Kerttula H, Cole DK, Rizkallah PJ, Parker AL.

Nat Commun. 2019 Feb 14;10(1):741. doi: 10.1038/s41467-019-08599-y.

20.

Percutaneous Tibial Fracture Reduction Using Computed Tomography Imaging, Computer Modelling and 3D Printed Alignment Constructs: A Cadaveric Study.

Lynch AC, Davies JA.

Vet Comp Orthop Traumatol. 2019 Mar;32(2):139-148. doi: 10.1055/s-0039-1677751. Epub 2019 Feb 13.

PMID:
30759484
21.

Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development.

Munro DAD, Wineberg Y, Tarnick J, Vink CS, Li Z, Pridans C, Dzierzak E, Kalisky T, Hohenstein P, Davies JA.

Elife. 2019 Feb 13;8. pii: e43271. doi: 10.7554/eLife.43271.

22.

Investigating Aspects of Renal Physiology and Pharmacology in Organ and Organoid Culture.

Lawrence ML, Elhendawi M, Davies JA.

Methods Mol Biol. 2019;1926:127-142. doi: 10.1007/978-1-4939-9021-4_11.

PMID:
30742268
23.

An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis.

Lees NR, Han LC, Byrne MJ, Davies JA, Parnell AE, Moreland PEJ, Stach JEM, van der Kamp MW, Willis CL, Race PR.

Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2305-2309. doi: 10.1002/anie.201812105. Epub 2019 Jan 21.

PMID:
30664319
24.

Real-World Synthetic Biology: Is It Founded on an Engineering Approach, and Should It Be?

Davies JA.

Life (Basel). 2019 Jan 7;9(1). pii: E6. doi: 10.3390/life9010006.

25.

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

Sawhney JP, Kothiwale VA, Bisne V, Durgaprasad R, Jadhav P, Chopda M, Vanajakshamma V, Meena R, Vijayaraghavan G, Chawla K, Allu J, Pieper KS, John Camm A, Kakkar AK; GARFIELD-AF Investigators.

Indian Heart J. 2018 Nov - Dec;70(6):828-835. doi: 10.1016/j.ihj.2018.09.001. Epub 2018 Sep 12.

26.

Development and validation of a haematuria cancer risk score to identify patients at risk of harbouring cancer.

Tan WS, Ahmad A, Feber A, Mostafid H, Cresswell J, Fankhauser CD, Waisbrod S, Hermanns T, Sasieni P, Kelly JD; DETECT I trial collaborators.

J Intern Med. 2019 Apr;285(4):436-445. doi: 10.1111/joim.12868. Epub 2019 Jan 4.

27.

Dimers of acetic acid in helium nanodroplets.

Davies JA, Hanson-Heine MWD, Besley NA, Shirley A, Trowers J, Yang S, Ellis AM.

Phys Chem Chem Phys. 2019 Jul 3;21(26):13950-13958. doi: 10.1039/c8cp05934a.

PMID:
30394472
28.

A new guide to immunopharmacology.

Harding SD, Faccenda E, Southan C, Maffia P, Davies JA.

Nat Rev Immunol. 2018 Dec;18(12):729. doi: 10.1038/s41577-018-0079-2. No abstract available.

PMID:
30327546
29.

Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells.

Baaske J, Gonschorek P, Engesser R, Dominguez-Monedero A, Raute K, Fischbach P, Müller K, Cachat E, Schamel WWA, Minguet S, Davies JA, Timmer J, Weber W, Zurbriggen MD.

Sci Rep. 2018 Oct 9;8(1):15024. doi: 10.1038/s41598-018-32929-7.

30.

Metal- and Oxidant-Free Alkenyl C-H/Aromatic C-H Cross-Coupling Using Electrochemically Generated Iodosulfonium Ions.

Hayashi R, Shimizu A, Davies JA, Ishizaki Y, Willis C, Yoshida JI.

Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12891-12895. doi: 10.1002/anie.201807592. Epub 2018 Aug 29.

PMID:
30156746
31.

Tamoxifen- and Mifepristone-Inducible Versions of CRISPR Effectors, Cas9 and Cpf1.

Dominguez-Monedero A, Davies JA.

ACS Synth Biol. 2018 Sep 21;7(9):2160-2169. doi: 10.1021/acssynbio.8b00145. Epub 2018 Sep 4.

32.

Challenges of Connecting Chemistry to Pharmacology: Perspectives from Curating the IUPHAR/BPS Guide to PHARMACOLOGY.

Southan C, Sharman JL, Faccenda E, Pawson AJ, Harding SD, Davies JA.

ACS Omega. 2018 Jul 31;3(7):8408-8420. doi: 10.1021/acsomega.8b00884. Review.

33.

SynPharm: A Guide to PHARMACOLOGY Database Tool for Designing Drug Control into Engineered Proteins.

Ireland SM, Southan C, Dominguez-Monedero A, Harding SD, Sharman JL, Davies JA.

ACS Omega. 2018 Jul 31;3(7):7993-8002. doi: 10.1021/acsomega.8b00659. Epub 2018 Jul 18.

34.

Accessing Expert-Curated Pharmacological Data in the IUPHAR/BPS Guide to PHARMACOLOGY.

Sharman JL, Harding SD, Southan C, Faccenda E, Pawson AJ, Davies JA; NC-IUPHAR.

Curr Protoc Bioinformatics. 2018 Mar;61(1):1.34.1-1.34.46. doi: 10.1002/cpbi.46.

PMID:
30040201
35.

Does urinary cytology have a role in haematuria investigations?

Tan WS, Sarpong R, Khetrapal P, Rodney S, Mostafid H, Cresswell J, Watson D, Rane A, Hicks J, Hellawell G, Davies M, Srirangam SJ, Dawson L, Payne D, Williams N, Brew-Graves C, Feber A, Kelly JD; DETECT I trial collaborators.

BJU Int. 2019 Jan;123(1):74-81. doi: 10.1111/bju.14459. Epub 2018 Aug 29.

36.

Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus.

Hulin-Curtis SL, Davies JA, Jones R, Hudson E, Hanna L, Chester JD, Parker AL.

Oncotarget. 2018 May 29;9(41):26328-26341. doi: 10.18632/oncotarget.25242. eCollection 2018 May 29.

37.

Ad5NULL-A20: A Tropism-Modified, αvβ6 Integrin-Selective Oncolytic Adenovirus for Epithelial Ovarian Cancer Therapies.

Uusi-Kerttula H, Davies JA, Thompson JM, Wongthida P, Evgin L, Shim KG, Bradshaw A, Baker AT, Rizkallah PJ, Jones R, Hanna L, Hudson E, Vile RG, Chester JD, Parker AL.

Clin Cancer Res. 2018 Sep 1;24(17):4215-4224. doi: 10.1158/1078-0432.CCR-18-1089. Epub 2018 May 24.

38.

Vascularizing the Kidney in the Embryo and Organoid: Questioning Assumptions about Renal Vasculogenesis.

Munro DAD, Davies JA.

J Am Soc Nephrol. 2018 Jun;29(6):1593-1595. doi: 10.1681/ASN.2018020179. Epub 2018 May 10. No abstract available.

39.

Impact of two centuries of intensive agriculture on soil carbon, nitrogen and phosphorus cycling in the UK.

Muhammed SE, Coleman K, Wu L, Bell VA, Davies JAC, Quinton JN, Carnell EJ, Tomlinson SJ, Dore AJ, Dragosits U, Naden PS, Glendining MJ, Tipping E, Whitmore AP.

Sci Total Environ. 2018 Sep 1;634:1486-1504. doi: 10.1016/j.scitotenv.2018.03.378. Epub 2018 Apr 18.

40.

Functional transport of organic anions and cations in the murine mesonephros.

Lawrence ML, Smith JR, Davies JA.

Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F130-F137. doi: 10.1152/ajprenal.00021.2018. Epub 2018 Mar 21.

41.

Sebinger Culture: A System Optimized for Morphological Maturation and Imaging of Cultured Mouse Metanephric Primordia.

Elhendawi M, Davies JA.

Bio Protoc. 2018 Feb 20;8(4). pii: e2730. doi: 10.21769/BioProtoc.2730.

42.

The Novel Oncolytic Adenoviral Mutant Ad5-3Δ-A20T Retargeted to αvβ6 Integrins Efficiently Eliminates Pancreatic Cancer Cells.

Man YKS, Davies JA, Coughlan L, Pantelidou C, Blázquez-Moreno A, Marshall JF, Parker AL, Halldén G.

Mol Cancer Ther. 2018 Feb;17(2):575-587. doi: 10.1158/1535-7163.MCT-17-0671.

43.

Organizing Organoids: Stem Cells Branch Out.

Davies JA.

Cell Stem Cell. 2017 Dec 7;21(6):705-706. doi: 10.1016/j.stem.2017.11.011.

44.

Heterologous expression reveals the biosynthesis of the antibiotic pleuromutilin and generates bioactive semi-synthetic derivatives.

Alberti F, Khairudin K, Venegas ER, Davies JA, Hayes PM, Willis CL, Bailey AM, Foster GD.

Nat Commun. 2017 Nov 28;8(1):1831. doi: 10.1038/s41467-017-01659-1.

45.

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY.

Harding SD, Sharman JL, Faccenda E, Southan C, Pawson AJ, Ireland S, Gray AJG, Bruce L, Alexander SPH, Anderton S, Bryant C, Davenport AP, Doerig C, Fabbro D, Levi-Schaffer F, Spedding M, Davies JA; NC-IUPHAR.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1091-D1106. doi: 10.1093/nar/gkx1121.

46.

Asymmetric BMP4 signalling improves the realism of kidney organoids.

Mills CG, Lawrence ML, Munro DAD, Elhendawi M, Mullins JJ, Davies JA.

Sci Rep. 2017 Nov 1;7(1):14824. doi: 10.1038/s41598-017-14809-8.

47.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors.

Alexander SP, Christopoulos A, Davenport AP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2017 Dec;174 Suppl 1:S17-S129. doi: 10.1111/bph.13878.

48.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Other ion channels.

Alexander SP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2017 Dec;174 Suppl 1:S195-S207. doi: 10.1111/bph.13881.

49.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Ligand-gated ion channels.

Alexander SP, Peters JA, Kelly E, Marrion NV, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2017 Dec;174 Suppl 1:S130-S159. doi: 10.1111/bph.13879.

50.

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview.

Alexander SP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Buneman OP, Cidlowski JA, Christopoulos A, Davenport AP, Fabbro D, Spedding M, Striessnig J, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2017 Dec;174 Suppl 1:S1-S16. doi: 10.1111/bph.13882.

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