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Items: 1 to 50 of 454

1.

Assessing the ability of silage lactic acid bacteria to incorporate and transform inorganic selenium within laboratory scale silos.

Lee MRF, Fleming HR, Cogan T, Hodgson C, Davies DR.

Anim Feed Sci Technol. 2019 Jun;253:125-134. doi: 10.1016/j.anifeedsci.2019.05.011.

2.

58-Year-Old Asymptomatic Man With Left Ventricular Hypertrophy.

Davies DR, Bhatia S, Geske JB.

Mayo Clin Proc. 2019 Jul;94(7):1330-1333. doi: 10.1016/j.mayocp.2018.11.038. No abstract available.

PMID:
31272575
3.

A review of our current understanding of parasite survival in silage and stored forages, with a focus on Fasciola hepatica metacercariae.

John BC, Davies DR, Williams DJL, Hodgkinson JE.

Grass Forage Sci. 2019 Jun;74(2):211-217. doi: 10.1111/gfs.12429. Epub 2019 May 7. Review.

4.

Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison.

Nittinger E, Gibbons P, Eigenbrot C, Davies DR, Maurer B, Yu CL, Kiefer JR, Kuglstatter A, Murray J, Ortwine DF, Tang Y, Tsui V.

J Comput Aided Mol Des. 2019 Mar;33(3):307-330. doi: 10.1007/s10822-019-00187-y. Epub 2019 Feb 12.

PMID:
30756207
5.

Structure and analysis of nucleoside diphosphate kinase from Borrelia burgdorferi prepared in a transition-state complex with ADP and vanadate moieties.

Dumais M, Davies DR, Lin T, Staker BL, Myler PJ, Van Voorhis WC.

Acta Crystallogr F Struct Biol Commun. 2018 Jun 1;74(Pt 6):373-384. doi: 10.1107/S2053230X18007392. Epub 2018 May 31.

6.

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).

Rai G, Brimacombe KR, Mott BT, Urban DJ, Hu X, Yang SM, Lee TD, Cheff DM, Kouznetsova J, Benavides GA, Pohida K, Kuenstner EJ, Luci DK, Lukacs CM, Davies DR, Dranow DM, Zhu H, Sulikowski G, Moore WJ, Stott GM, Flint AJ, Hall MD, Darley-Usmar VM, Neckers LM, Dang CV, Waterson AG, Simeonov A, Jadhav A, Maloney DJ.

J Med Chem. 2017 Nov 22;60(22):9184-9204. doi: 10.1021/acs.jmedchem.7b00941. Epub 2017 Nov 9.

7.

The concurrent emergence and causes of double volcanic hotspot tracks on the Pacific plate.

Jones TD, Davies DR, Campbell IH, Iaffaldano G, Yaxley G, Kramer SC, Wilson CR.

Nature. 2017 May 25;545(7655):472-476. doi: 10.1038/nature22054. Epub 2017 May 3.

PMID:
28467819
8.

Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.

Ojo KK, Ranade RM, Zhang Z, Dranow DM, Myers JB, Choi R, Nakazawa Hewitt S, Edwards TE, Davies DR, Lorimer D, Boyle SM, Barrett LK, Buckner FS, Fan E, Van Voorhis WC.

PLoS One. 2016 Sep 22;11(9):e0163641. doi: 10.1371/journal.pone.0163641. eCollection 2016.

9.

Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.

Ojo KK, Ranade RM, Zhang Z, Dranow DM, Myers JB, Choi R, Nakazawa Hewitt S, Edwards TE, Davies DR, Lorimer D, Boyle SM, Barrett LK, Buckner FS, Fan E, Van Voorhis WC.

PLoS One. 2016 Aug 8;11(8):e0160350. doi: 10.1371/journal.pone.0160350. eCollection 2016. Erratum in: PLoS One. 2016;11(9):e0163641.

10.

Assessment of dietary ratios of red clover and corn silages on milk production and milk quality in dairy cows.

Moorby JM, Ellis NM, Davies DR.

J Dairy Sci. 2016 Oct;99(10):7982-7992. doi: 10.3168/jds.2016-11150. Epub 2016 Jul 27.

11.

Differential effects of glucocorticoid and mineralocorticoid antagonism on anxiety behavior in mild traumatic brain injury.

Fox LC, Davies DR, Scholl JL, Watt MJ, Forster GL.

Behav Brain Res. 2016 Oct 1;312:362-5. doi: 10.1016/j.bbr.2016.06.048. Epub 2016 Jun 27.

PMID:
27363926
12.

Mild Traumatic Brain Injury with Social Defeat Stress Alters Anxiety, Contextual Fear Extinction, and Limbic Monoamines in Adult Rats.

Davies DR, Olson D, Meyer DL, Scholl JL, Watt MJ, Manzerra P, Renner KJ, Forster GL.

Front Behav Neurosci. 2016 Apr 19;10:71. doi: 10.3389/fnbeh.2016.00071. eCollection 2016.

13.

Embracing proteins: structural themes in aptamer-protein complexes.

Gelinas AD, Davies DR, Janjic N.

Curr Opin Struct Biol. 2016 Feb;36:122-32. doi: 10.1016/j.sbi.2016.01.009. Epub 2016 Feb 24. Review.

14.

Strong, Multi-Scale Heterogeneity in Earth's Lowermost Mantle.

Tkalčić H, Young M, Muir JB, Davies DR, Mattesini M.

Sci Rep. 2015 Dec 17;5:18416. doi: 10.1038/srep18416.

15.

Lithospheric controls on magma composition along Earth's longest continental hotspot track.

Davies DR, Rawlinson N, Iaffaldano G, Campbell IH.

Nature. 2015 Sep 24;525(7570):511-4. doi: 10.1038/nature14903. Epub 2015 Sep 14.

PMID:
26367795
16.

Increased dopamine transporter function as a mechanism for dopamine hypoactivity in the adult infralimbic medial prefrontal cortex following adolescent social stress.

Novick AM, Forster GL, Hassell JE, Davies DR, Scholl JL, Renner KJ, Watt MJ.

Neuropharmacology. 2015 Oct;97:194-200. doi: 10.1016/j.neuropharm.2015.05.032. Epub 2015 Jun 6.

17.

Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.

Jarvis TC, Davies DR, Hisaminato A, Resnicow DI, Gupta S, Waugh SM, Nagabukuro A, Wadatsu T, Hishigaki H, Gawande B, Zhang C, Wolk SK, Mayfield WS, Nakaishi Y, Burgin AB, Stewart LJ, Edwards TE, Gelinas AD, Schneider DJ, Janjic N.

Structure. 2015 Jul 7;23(7):1293-304. doi: 10.1016/j.str.2015.03.027. Epub 2015 May 28.

18.

Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.

Phan IQ, Davies DR, Moretti NS, Shanmugam D, Cestari I, Anupama A, Fairman JW, Edwards TE, Stuart K, Schenkman S, Myler PJ.

Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):615-21. doi: 10.1107/S2053230X15004185. Epub 2015 May 7.

19.

Screening Ligands by X-ray crystallography.

Davies DR.

Methods Mol Biol. 2014;1140:315-23. doi: 10.1007/978-1-4939-0354-2_23.

PMID:
24590727
20.

Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand.

Gelinas AD, Davies DR, Edwards TE, Rohloff JC, Carter JD, Zhang C, Gupta S, Ishikawa Y, Hirota M, Nakaishi Y, Jarvis TC, Janjic N.

J Biol Chem. 2014 Mar 21;289(12):8720-34. doi: 10.1074/jbc.M113.532697. Epub 2014 Jan 12.

21.

Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.

Davies DR, Gelinas AD, Zhang C, Rohloff JC, Carter JD, O'Connell D, Waugh SM, Wolk SK, Mayfield WS, Burgin AB, Edwards TE, Stewart LJ, Gold L, Janjic N, Jarvis TC.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19971-6. doi: 10.1073/pnas.1213933109. Epub 2012 Nov 8.

22.

Young drivers' perceptions of culpability of sleep-deprived versus drinking drivers.

Williams LR, Davies DR, Thiele K, Davidson JR, MacLean AW.

J Safety Res. 2012 Apr;43(2):115-22. doi: 10.1016/j.jsr.2012.02.002. Epub 2012 Mar 9.

PMID:
22709996
23.

Mild traumatic brain injury in the rat alters neuronal number in the limbic system and increases conditioned fear and anxiety-like behaviors.

Meyer DL, Davies DR, Barr JL, Manzerra P, Forster GL.

Exp Neurol. 2012 Jun;235(2):574-87. doi: 10.1016/j.expneurol.2012.03.012. Epub 2012 Apr 1.

PMID:
22498103
24.

Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening.

Begley DW, Davies DR, Hartley RC, Hewitt SN, Rychel AL, Myler PJ, Van Voorhis WC, Staker BL, Stewart LJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1060-9. doi: 10.1107/S1744309111014436. Epub 2011 Aug 13.

25.

An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase.

Davies DR, Staker BL, Abendroth JA, Edwards TE, Hartley R, Leonard J, Kim H, Rychel AL, Hewitt SN, Myler PJ, Stewart LJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1044-50. doi: 10.1107/S1744309111030405. Epub 2011 Aug 13.

26.

The structural biology of Toll-like receptors.

Botos I, Segal DM, Davies DR.

Structure. 2011 Apr 13;19(4):447-59. doi: 10.1016/j.str.2011.02.004. Review.

27.

Fragment screening of infectious disease targets in a structural genomics environment.

Begley DW, Davies DR, Hartley RC, Edwards TE, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ.

Methods Enzymol. 2011;493:533-56. doi: 10.1016/B978-0-12-381274-2.00021-2.

28.

Predicting the success of fragment screening by X-ray crystallography.

Davies DR, Begley DW, Hartley RC, Staker BL, Stewart LJ.

Methods Enzymol. 2011;493:91-114. doi: 10.1016/B978-0-12-381274-2.00004-2.

PMID:
21371588
29.

Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.

Begley DW, Hartley RC, Davies DR, Edwards TE, Leonard JT, Abendroth J, Burris CA, Bhandari J, Myler PJ, Staker BL, Stewart LJ.

J Struct Funct Genomics. 2011 Jul;12(2):63-76. doi: 10.1007/s10969-011-9102-6. Epub 2011 Feb 26.

30.

Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.

Di Paolo JA, Huang T, Balazs M, Barbosa J, Barck KH, Bravo BJ, Carano RA, Darrow J, Davies DR, DeForge LE, Diehl L, Ferrando R, Gallion SL, Giannetti AM, Gribling P, Hurez V, Hymowitz SG, Jones R, Kropf JE, Lee WP, Maciejewski PM, Mitchell SA, Rong H, Staker BL, Whitney JA, Yeh S, Young WB, Yu C, Zhang J, Reif K, Currie KS.

Nat Chem Biol. 2011 Jan;7(1):41-50. doi: 10.1038/nchembio.481. Epub 2010 Nov 28.

PMID:
21113169
31.

Dimerization of Toll-like receptor 3 (TLR3) is required for ligand binding.

Wang Y, Liu L, Davies DR, Segal DM.

J Biol Chem. 2010 Nov 19;285(47):36836-41. doi: 10.1074/jbc.M110.167973. Epub 2010 Sep 22.

32.

Identifying regulators for EAG1 channels with a novel electrophysiology and tryptophan fluorescence based screen.

Brelidze TI, Carlson AE, Davies DR, Stewart LJ, Zagotta WN.

PLoS One. 2010 Sep 2;5(9). pii: e12523. doi: 10.1371/journal.pone.0012523.

33.

Spectroscopic and modeling investigations of the gas phase chemistry and composition in microwave plasma activated B2H6/CH4/Ar/H2 mixtures.

Ma J, Richley JC, Davies DR, Ashfold MN.

J Phys Chem A. 2010 Sep 23;114(37):10076-89. doi: 10.1021/jp104532y.

PMID:
20735120
34.

Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.

35.

Induced-fit mechanism for prolyl endopeptidase.

Li M, Chen C, Davies DR, Chiu TK.

J Biol Chem. 2010 Jul 9;285(28):21487-95. doi: 10.1074/jbc.M109.092692. Epub 2010 May 5.

36.

Solution conformation and dynamics of the HIV-1 integrase core domain.

Fitzkee NC, Masse JE, Shen Y, Davies DR, Bax A.

J Biol Chem. 2010 Jun 4;285(23):18072-84. doi: 10.1074/jbc.M110.113407. Epub 2010 Apr 1.

37.

Spectroscopic and modeling investigations of the gas-phase chemistry and composition in microwave plasma activated B2H6/Ar/H2 mixtures.

Ma J, Richley JC, Davies DR, Cheesman A, Ashfold MN, Mankelevich YA.

J Phys Chem A. 2010 Feb 25;114(7):2447-63. doi: 10.1021/jp9094694.

PMID:
20121057
38.

Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.

Sandanayaka V, Mamat B, Mishra RK, Winger J, Krohn M, Zhou LM, Keyvan M, Enache L, Sullins D, Onua E, Zhang J, Halldorsdottir G, Sigthorsdottir H, Thorlaksdottir A, Sigthorsson G, Thorsteinnsdottir M, Davies DR, Stewart LJ, Zembower DE, Andresson T, Kiselyov AS, Singh J, Gurney ME.

J Med Chem. 2010 Jan 28;53(2):573-85. doi: 10.1021/jm900838g.

PMID:
19950900
39.

Effects of impurities on membrane-protein crystallization in different systems.

Kors CA, Wallace E, Davies DR, Li L, Laible PD, Nollert P.

Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1062-73. doi: 10.1107/S0907444909029163. Epub 2009 Sep 16.

40.

The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel mechanism of relaxing the target for tumorigenic somatic APC mutations.

Dallosso AR, Jones S, Azzopardi D, Moskvina V, Al-Tassan N, Williams GT, Idziaszczyk S, Davies DR, Milewski P, Williams S, Beynon J, Sampson JR, Cheadle JP.

Hum Mutat. 2009 Oct;30(10):1412-8. doi: 10.1002/humu.21089.

PMID:
19701947
41.

Remission of histiocytic ulcerative colitis in Boxer dogs correlates with eradication of invasive intramucosal Escherichia coli.

Mansfield CS, James FE, Craven M, Davies DR, O'Hara AJ, Nicholls PK, Dogan B, MacDonough SP, Simpson KW.

J Vet Intern Med. 2009 Sep-Oct;23(5):964-9. doi: 10.1111/j.1939-1676.2009.0363.x. Epub 2009 Aug 11.

42.

Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.

Davies DR, Mamat B, Magnusson OT, Christensen J, Haraldsson MH, Mishra R, Pease B, Hansen E, Singh J, Zembower D, Kim H, Kiselyov AS, Burgin AB, Gurney ME, Stewart LJ.

J Med Chem. 2009 Aug 13;52(15):4694-715. doi: 10.1021/jm900259h. Erratum in: J Med Chem. 2010 Mar 11;53(5):2330-1.

43.

The toll-like receptor 3:dsRNA signaling complex.

Botos I, Liu L, Wang Y, Segal DM, Davies DR.

Biochim Biophys Acta. 2009 Sep-Oct;1789(9-10):667-74. doi: 10.1016/j.bbagrm.2009.06.005. Epub 2009 Jul 9. Review.

44.

Assessment of dietary ratios of red clover and grass silages on milk production and milk quality in dairy cows.

Moorby JM, Lee MR, Davies DR, Kim EJ, Nute GR, Ellis NM, Scollan ND.

J Dairy Sci. 2009 Mar;92(3):1148-60. doi: 10.3168/jds.2008-1771.

45.

Structure of PolC reveals unique DNA binding and fidelity determinants.

Evans RJ, Davies DR, Bullard JM, Christensen J, Green LS, Guiles JW, Pata JD, Ribble WK, Janjic N, Jarvis TC.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20695-700. doi: 10.1073/pnas.0809989106. Epub 2008 Dec 23.

46.

Principles of macromolecular X-ray crystallography.

Hickman AB, Davies DR.

Curr Protoc Protein Sci. 2001 May;Chapter 17:Unit 17.3. doi: 10.1002/0471140864.ps1703s10.

PMID:
18429137
47.

Structural basis of toll-like receptor 3 signaling with double-stranded RNA.

Liu L, Botos I, Wang Y, Leonard JN, Shiloach J, Segal DM, Davies DR.

Science. 2008 Apr 18;320(5874):379-81. doi: 10.1126/science.1155406.

48.

Hypokalaemic paresis, hypertension, alkalosis and adrenal-dependent hyperadrenocorticism in a dog.

Davies DR, Foster SF, Hopper BJ, Staudte KL, O'Hara AJ, Irwin PJ.

Aust Vet J. 2008 Apr;86(4):139-46. doi: 10.1111/j.1751-0813.2008.00276.x.

PMID:
18363988
49.

Inherited myopathy in a Great Dane.

Davies SE, Davies DR, Richards RB, Bruce WJ.

Aust Vet J. 2008 Jan-Feb;86(1-2):43-5. doi: 10.1111/j.1751-0813.2007.00202.x. No abstract available.

PMID:
18271825
50.

The TLR3 signaling complex forms by cooperative receptor dimerization.

Leonard JN, Ghirlando R, Askins J, Bell JK, Margulies DH, Davies DR, Segal DM.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):258-63. doi: 10.1073/pnas.0710779105. Epub 2008 Jan 2.

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