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Items: 1 to 50 of 156

1.

Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes.

Khan S, Jain A, Taghavian O, Nakajima R, Jasinskas A, Supnet M, Felgner J, Davies J, de Assis RR, Jan S, Obiero J, Strahsburger E, Pone EJ, Liang L, Davies DH, Felgner PL.

J Vis Exp. 2019 Jul 26;(149). doi: 10.3791/59973.

PMID:
31403629
2.

Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses.

Albin TJ, Tom JK, Manna S, Gilkes AP, Stetkevich SA, Katz BB, Supnet M, Felgner J, Jain A, Nakajima R, Jasinskas A, Zlotnik A, Pearlman E, Davies DH, Felgner PL, Burkhardt AM, Esser-Kahn AP.

ACS Cent Sci. 2019 Jul 24;5(7):1137-1145. doi: 10.1021/acscentsci.8b00823. Epub 2019 Jun 27.

3.

Naturally acquired immunity against immature Plasmodium falciparum gametocytes.

Dantzler KW, Ma S, Ngotho P, Stone WJR, Tao D, Rijpma S, De Niz M, Nilsson Bark SK, Jore MM, Raaijmakers TK, Early AM, Ubaida-Mohien C, Lemgruber L, Campo JJ, Teng AA, Le TQ, Walker CL, Hermand P, Deterre P, Davies DH, Felgner P, Morlais I, Wirth DF, Neafsey DE, Dinglasan RR, Laufer M, Huttenhower C, Seydel K, Taylor T, Bousema T, Marti M.

Sci Transl Med. 2019 Jun 5;11(495). pii: eaav3963. doi: 10.1126/scitranslmed.aav3963.

4.

Distinct Antibody Signatures Associated with Different Malaria Transmission Intensities in Zambia and Zimbabwe.

Kobayashi T, Jain A, Liang L, Obiero JM, Hamapumbu H, Stevenson JC, Thuma PE, Lupiya J, Chaponda M, Mulenga M, Mamini E, Mharakurwa S, Gwanzura L, Munyati S, Mutambu S, Felgner P, Davies DH, Moss WJ.

mSphere. 2019 Mar 27;4(2). pii: e00061-19. doi: 10.1128/mSphereDirect.00061-19.

5.

Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis.

Obiero JM, Campo JJ, Scholzen A, Randall A, Bijker EM, Roestenberg M, Hermsen CC, Teng A, Jain A, Davies DH, Sauerwein RW, Felgner PL.

mSphere. 2019 Feb 20;4(1). pii: e00027-19. doi: 10.1128/mSphereDirect.00027-19.

6.

Protein Microarray Analysis of the Specificity and Cross-Reactivity of Influenza Virus Hemagglutinin-Specific Antibodies.

Nakajima R, Supnet M, Jasinskas A, Jain A, Taghavian O, Obiero J, Milton DK, Chen WH, Grantham M, Webby R, Krammer F, Carter D, Felgner PL, Davies DH.

mSphere. 2018 Dec 12;3(6). pii: e00592-18. doi: 10.1128/mSphere.00592-18.

7.

Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts.

Döşkaya M, Liang L, Jain A, Can H, Gülçe İz S, Felgner PL, Değirmenci Döşkaya A, Davies DH, Gürüz AY.

Parasit Vectors. 2018 Jul 4;11(1):393. doi: 10.1186/s13071-018-2934-1.

8.

Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections.

Taghavian O, Jain A, Joyner CJ, Ketchum S, Nakajima R, Jasinskas A, Liang L, Fong R, King C, Greenhouse B, Murphy M, Bailey J, Galinski MR, Barnwell JW, Plowe CV, Davies DH, Felgner PL.

Proteomics. 2018 Jul;18(13):e1870115. doi: 10.1002/pmic.201870115. Epub 2018 Jun 11. No abstract available.

PMID:
29963771
9.

Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections.

Taghavian O, Jain A, Joyner CJ, Ketchum S, Nakajima R, Jasinskas A, Liang L, Fong R, King C, Greenhouse B, Murphy M, Bailey J, Galinski MR, Barnwell JW, Plowe CV, Davies DH, Felgner PL.

Proteomics. 2018 Jan;18(2). doi: 10.1002/pmic.201700277. Erratum in: Proteomics. 2018 Jul;18(13):e1870115.

10.

The Community Dental Service in Abertawe Bro Morgannwg University Health Board.

Davies DHJ.

Br J Community Nurs. 2017 Jul 2;22(7):318-320. doi: 10.12968/bjcn.2017.22.7.318. No abstract available.

PMID:
28686096
11.

Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children.

Felgner J, Jain A, Nakajima R, Liang L, Jasinskas A, Gotuzzo E, Vinetz JM, Miyajima F, Pirmohamed M, Hassan-Hanga F, Umoru D, Jibir BW, Gambo S, Olateju K, Felgner PL, Obaro S, Davies DH.

PLoS Negl Trop Dis. 2017 Jun 22;11(6):e0005679. doi: 10.1371/journal.pntd.0005679. eCollection 2017 Jun.

12.

An evaluation of purified Salmonella Typhi protein antigens for the serological diagnosis of acute typhoid fever.

Tran Vu Thieu N, Trinh Van T, Tran Tuan A, Klemm EJ, Nguyen Ngoc Minh C, Voong Vinh P, Pham Thanh D, Ho Ngoc Dan T, Pham Duc T, Langat P, Martin LB, Galan J, Liang L, Felgner PL, Davies DH, de Jong HK, Maude RR, Fukushima M, Wijedoru L, Ghose A, Samad R, Dondorp AM, Faiz A, Darton TC, Pollard AJ, Thwaites GE, Dougan G, Parry CM, Baker S.

J Infect. 2017 Aug;75(2):104-114. doi: 10.1016/j.jinf.2017.05.007. Epub 2017 May 25.

13.

Treatment of Chronic Asymptomatic Plasmodium falciparum Infection Does Not Increase the Risk of Clinical Malaria Upon Reinfection.

Portugal S, Tran TM, Ongoiba A, Bathily A, Li S, Doumbo S, Skinner J, Doumtabe D, Kone Y, Sangala J, Jain A, Davies DH, Hung C, Liang L, Ricklefs S, Homann MV, Felgner PL, Porcella SF, Färnert A, Doumbo OK, Kayentao K, Greenwood BM, Traore B, Crompton PD.

Clin Infect Dis. 2017 Mar 1;64(5):645-653. doi: 10.1093/cid/ciw849.

14.

Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays.

Uplekar S, Rao PN, Ramanathapuram L, Awasthi V, Verma K, Sutton P, Ali SZ, Patel A, G SL, Ravishankaran S, Desai N, Tandel N, Choubey S, Barla P, Kanagaraj D, Eapen A, Pradhan K, Singh R, Jain A, Felgner PL, Davies DH, Carlton JM, Das J.

PLoS Negl Trop Dis. 2017 Jan 24;11(1):e0005323. doi: 10.1371/journal.pntd.0005323. eCollection 2017 Jan.

15.

Serodiagnosis of Acute Typhoid Fever in Nigerian Pediatric Cases by Detection of Serum IgA and IgG Against Hemolysin E and Lipopolysaccharide.

Davies DH, Jain A, Nakajima R, Liang L, Jasinskis A, Supnet M, Felgner PL, Teng A, Pablo J, Molina DM, Obaro SK.

Am J Trop Med Hyg. 2016 Aug 3;95(2):431-9. doi: 10.4269/ajtmh.15-0869. Epub 2016 May 23.

16.

Towards Development of Improved Serodiagnostics for Tularemia by Use of Francisella tularensis Proteome Microarrays.

Nakajima R, Escudero R, Molina DM, Rodríguez-Vargas M, Randall A, Jasinskas A, Pablo J, Felgner PL, AuCoin DP, Anda P, Davies DH.

J Clin Microbiol. 2016 Jul;54(7):1755-1765. doi: 10.1128/JCM.02784-15. Epub 2016 Apr 20.

17.

Antibody Profiling in Naïve and Semi-immune Individuals Experimentally Challenged with Plasmodium vivax Sporozoites.

Arévalo-Herrera M, Lopez-Perez M, Dotsey E, Jain A, Rubiano K, Felgner PL, Davies DH, Herrera S.

PLoS Negl Trop Dis. 2016 Mar 25;10(3):e0004563. doi: 10.1371/journal.pntd.0004563. eCollection 2016 Mar.

18.

Evaluation of quantum dot immunofluorescence and a digital CMOS imaging system as an alternative to conventional organic fluorescence dyes and laser scanning for quantifying protein microarrays.

Jain A, Taghavian O, Vallejo D, Dotsey E, Schwartz D, Bell FG, Greef C, Davies DH, Grudzien J, Lee AP, Felgner PL, Liang L.

Proteomics. 2016 Apr;16(8):1271-9. doi: 10.1002/pmic.201500375. Epub 2016 Mar 29.

19.

Modulation of Innate Immune Responses via Covalently Linked TLR Agonists.

Tom JK, Dotsey EY, Wong HY, Stutts L, Moore T, Davies DH, Felgner PL, Esser-Kahn AP.

ACS Cent Sci. 2015 Nov 25;1(8):439-448. Epub 2015 Oct 28.

20.

Large screen approaches to identify novel malaria vaccine candidates.

Davies DH, Duffy P, Bodmer JL, Felgner PL, Doolan DL.

Vaccine. 2015 Dec 22;33(52):7496-505. doi: 10.1016/j.vaccine.2015.09.059. Epub 2015 Oct 1. Review.

21.

Genetic Resistance to Malaria Is Associated With Greater Enhancement of Immunoglobulin (Ig)M Than IgG Responses to a Broad Array of Plasmodium falciparum Antigens.

Arama C, Skinner J, Doumtabe D, Portugal S, Tran TM, Jain A, Traore B, Doumbo OK, Davies DH, Troye-Blomberg M, Dolo A, Felgner PL, Crompton PD.

Open Forum Infect Dis. 2015 Aug 26;2(3):ofv118. doi: 10.1093/ofid/ofv118. eCollection 2015 Sep.

22.

Biosignatures of Exposure/Transmission and Immunity.

King CL, Davies DH, Felgner P, Baum E, Jain A, Randall A, Tetteh K, Drakeley CJ, Greenhouse B.

Am J Trop Med Hyg. 2015 Sep;93(3 Suppl):16-27. doi: 10.4269/ajtmh.15-0037. Epub 2015 Aug 10.

23.

Plasmodium falciparum Protein Microarray Antibody Profiles Correlate With Protection From Symptomatic Malaria in Kenya.

Dent AE, Nakajima R, Liang L, Baum E, Moormann AM, Sumba PO, Vulule J, Babineau D, Randall A, Davies DH, Felgner PL, Kazura JW.

J Infect Dis. 2015 Nov 1;212(9):1429-38. doi: 10.1093/infdis/jiv224. Epub 2015 Apr 15. Erratum in: J Infect Dis. 2016 Jan 1;213(1):167.

24.

Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening.

Nayak K, Jing L, Russell RM, Davies DH, Hermanson G, Molina DM, Liang X, Sherman DR, Kwok WW, Yang J, Kenneth J, Ahamed SF, Chandele A, Murali-Krishna K, Koelle DM.

Tuberculosis (Edinb). 2015 May;95(3):275-87. doi: 10.1016/j.tube.2015.03.001. Epub 2015 Mar 27.

25.

Submicroscopic and asymptomatic Plasmodium falciparum and Plasmodium vivax infections are common in western Thailand - molecular and serological evidence.

Baum E, Sattabongkot J, Sirichaisinthop J, Kiattibutr K, Davies DH, Jain A, Lo E, Lee MC, Randall AZ, Molina DM, Liang X, Cui L, Felgner PL, Yan G.

Malar J. 2015 Feb 25;14:95. doi: 10.1186/s12936-015-0611-9.

26.

Identification of Toxoplasma gondii antigens associated with different types of infection by serum antibody profiling.

Felgner J, Juarez S, Hung C, Liang LI, Jain A, Döşkaya M, Felgner PL, Caner A, Gürüz Y, Davies DH.

Parasitology. 2015 May;142(6):827-38. doi: 10.1017/S0031182014001978. Epub 2015 Jan 14.

27.

T cell antigen discovery using soluble vaccinia proteome reveals recognition of antigens with both virion and nonvirion association.

Davies DH, Chun S, Hermanson G, Tucker JA, Jain A, Nakajima R, Pablo J, Felgner PL, Liang X.

J Immunol. 2014 Aug 15;193(4):1812-27. doi: 10.4049/jimmunol.1400663. Epub 2014 Jul 14.

28.

Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls.

Barton M, O'Brien K, Robinson JL, Davies DH, Simpson K, Asztalos E, Langley JM, Le Saux N, Sauve R, Synnes A, Tan B, de Repentigny L, Rubin E, Hui C, Kovacs L, Richardson SE.

BMC Infect Dis. 2014 Jun 12;14:327. doi: 10.1186/1471-2334-14-327.

29.

Immune profiling with a Salmonella Typhi antigen microarray identifies new diagnostic biomarkers of human typhoid.

Liang L, Juarez S, Nga TV, Dunstan S, Nakajima-Sasaki R, Davies DH, McSorley S, Baker S, Felgner PL.

Sci Rep. 2013;3:1043. doi: 10.1038/srep01043. Epub 2013 Jan 9.

30.

CD4 T-cell memory responses to viral infections of humans show pronounced immunodominance independent of duration or viral persistence.

Jing L, Schiffer JT, Chong TM, Bruckner JJ, Davies DH, Felgner PL, Haas J, Wald A, Verjans GM, Koelle DM.

J Virol. 2013 Mar;87(5):2617-27. doi: 10.1128/JVI.03047-12. Epub 2012 Dec 19.

31.

Humoral immunity to smallpox vaccines and monkeypox virus challenge: proteomic assessment and clinical correlations.

Townsend MB, Keckler MS, Patel N, Davies DH, Felgner P, Damon IK, Karem KL.

J Virol. 2013 Jan;87(2):900-11. doi: 10.1128/JVI.02089-12. Epub 2012 Nov 7.

32.

Identification of a common immune signature in murine and human systemic Salmonellosis.

Lee SJ, Liang L, Juarez S, Nanton MR, Gondwe EN, Msefula CL, Kayala MA, Necchi F, Heath JN, Hart P, Tsolis RM, Heyderman RS, MacLennan CA, Felgner PL, Davies DH, McSorley SJ.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4998-5003. doi: 10.1073/pnas.1111413109. Epub 2012 Feb 13.

33.

Discovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling.

Kalantari-Dehaghi M, Chun S, Chentoufi AA, Pablo J, Liang L, Dasgupta G, Molina DM, Jasinskas A, Nakajima-Sasaki R, Felgner J, Hermanson G, BenMohamed L, Felgner PL, Davies DH.

J Virol. 2012 Apr;86(8):4328-39. doi: 10.1128/JVI.05194-11. Epub 2012 Feb 8.

34.

Immunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individuals.

Dasgupta G, Chentoufi AA, Kalantari M, Falatoonzadeh P, Chun S, Lim CH, Felgner PL, Davies DH, BenMohamed L.

J Virol. 2012 Apr;86(8):4358-69. doi: 10.1128/JVI.07107-11. Epub 2012 Feb 8.

35.

Failure of the smallpox vaccine to develop a skin lesion in vaccinia virus-naïve individuals is related to differences in antibody profiles before vaccination, not after.

Tan X, Chun S, Pablo J, Felgner P, Liang X, Davies DH.

Clin Vaccine Immunol. 2012 Mar;19(3):418-28. doi: 10.1128/CVI.05521-11. Epub 2012 Jan 18.

36.

Measurement of antibody responses to Modified Vaccinia virus Ankara (MVA) and Dryvax(®) using proteome microarrays and development of recombinant protein ELISAs.

Hermanson G, Chun S, Felgner J, Tan X, Pablo J, Nakajima-Sasaki R, Molina DM, Felgner PL, Liang X, Davies DH.

Vaccine. 2012 Jan 11;30(3):614-25. doi: 10.1016/j.vaccine.2011.11.021. Epub 2011 Nov 17.

37.

Systems biology approach predicts antibody signature associated with Brucella melitensis infection in humans.

Liang L, Tan X, Juarez S, Villaverde H, Pablo J, Nakajima-Sasaki R, Gotuzzo E, Saito M, Hermanson G, Molina D, Felgner S, Morrow WJ, Liang X, Gilman RH, Davies DH, Tsolis RM, Vinetz JM, Felgner PL.

J Proteome Res. 2011 Oct 7;10(10):4813-24. doi: 10.1021/pr200619r. Epub 2011 Sep 8.

38.

Identification of circulating bacterial antigens by in vivo microbial antigen discovery.

Nuti DE, Crump RB, Dwi Handayani F, Chantratita N, Peacock SJ, Bowen R, Felgner PL, Davies DH, Wu T, Lyons CR, Brett PJ, Burtnick MN, Kozel TR, AuCoin DP.

MBio. 2011 Aug 16;2(4). pii: e00136-11. doi: 10.1128/mBio.00136-11. Print 2011.

39.

Identification of potential serodiagnostic and subunit vaccine antigens by antibody profiling of toxoplasmosis cases in Turkey.

Liang L, Döşkaya M, Juarez S, Caner A, Jasinskas A, Tan X, Hajagos BE, Bradley PJ, Korkmaz M, Gürüz Y, Felgner PL, Davies DH.

Mol Cell Proteomics. 2011 Jul;10(7):M110.006916. doi: 10.1074/mcp.M110.006916. Epub 2011 Apr 21.

40.

High-throughput profiling of the humoral immune responses against thirteen human papillomavirus types by proteome microarrays.

Luevano M, Bernard HU, Barrera-Saldaña HA, Trevino V, Garcia-Carranca A, Villa LL, Monk BJ, Tan X, Davies DH, Felgner PL, Kalantari M.

Virology. 2010 Sep 15;405(1):31-40. doi: 10.1016/j.virol.2010.05.011. Epub 2010 Jun 15.

41.

Defining the humoral immune response to infectious agents using high-density protein microarrays.

Vigil A, Davies DH, Felgner PL.

Future Microbiol. 2010 Feb;5(2):241-51. doi: 10.2217/fmb.09.127. Review.

42.

A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens.

Felgner PL, Kayala MA, Vigil A, Burk C, Nakajima-Sasaki R, Pablo J, Molina DM, Hirst S, Chew JS, Wang D, Tan G, Duffield M, Yang R, Neel J, Chantratita N, Bancroft G, Lertmemongkolchai G, Davies DH, Baldi P, Peacock S, Titball RW.

Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13499-504. doi: 10.1073/pnas.0812080106. Epub 2009 Jul 28.

43.

ORFeome approach to the clonal, HLA allele-specific CD4 T-cell response to a complex pathogen in humans.

Jing L, McCaughey SM, Davies DH, Chong TM, Felgner PL, De Rosa SC, Wilson CB, Koelle DM.

J Immunol Methods. 2009 Aug 15;347(1-2):36-45. doi: 10.1016/j.jim.2009.05.011. Epub 2009 Jun 9.

44.

Profiling humoral immune responses to P. falciparum infection with protein microarrays.

Doolan DL, Mu Y, Unal B, Sundaresh S, Hirst S, Valdez C, Randall A, Molina D, Liang X, Freilich DA, Oloo JA, Blair PL, Aguiar JC, Baldi P, Davies DH, Felgner PL.

Proteomics. 2008 Nov;8(22):4680-94. doi: 10.1002/pmic.200800194.

45.

Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities.

Sette A, Moutaftsi M, Moyron-Quiroz J, McCausland MM, Davies DH, Johnston RJ, Peters B, Rafii-El-Idrissi Benhnia M, Hoffmann J, Su HP, Singh K, Garboczi DN, Head S, Grey H, Felgner PL, Crotty S.

Immunity. 2008 Jun;28(6):847-58. doi: 10.1016/j.immuni.2008.04.018.

46.

An extremely diverse CD4 response to vaccinia virus in humans is revealed by proteome-wide T-cell profiling.

Jing L, Davies DH, Chong TM, Chun S, McClurkan CL, Huang J, Story BT, Molina DM, Hirst S, Felgner PL, Koelle DM.

J Virol. 2008 Jul;82(14):7120-34. doi: 10.1128/JVI.00453-08. Epub 2008 May 14. Erratum in: J Virol. 2009 Mar;83(5):2404.

47.

A genome-wide proteome array reveals a limited set of immunogens in natural infections of humans and white-footed mice with Borrelia burgdorferi.

Barbour AG, Jasinskas A, Kayala MA, Davies DH, Steere AC, Baldi P, Felgner PL.

Infect Immun. 2008 Aug;76(8):3374-89. doi: 10.1128/IAI.00048-08. Epub 2008 May 12.

48.

Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine.

Benhnia MR, McCausland MM, Su HP, Singh K, Hoffmann J, Davies DH, Felgner PL, Head S, Sette A, Garboczi DN, Crotty S.

J Virol. 2008 Apr;82(7):3751-68. doi: 10.1128/JVI.02244-07. Epub 2008 Jan 30.

49.

Antibody profiling by proteome microarray reveals the immunogenicity of the attenuated smallpox vaccine modified vaccinia virus ankara is comparable to that of Dryvax.

Davies DH, Wyatt LS, Newman FK, Earl PL, Chun S, Hernandez JE, Molina DM, Hirst S, Moss B, Frey SE, Felgner PL.

J Virol. 2008 Jan;82(2):652-63. Epub 2007 Oct 31.

50.

From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis.

Sundaresh S, Randall A, Unal B, Petersen JM, Belisle JT, Hartley MG, Duffield M, Titball RW, Davies DH, Felgner PL, Baldi P.

Bioinformatics. 2007 Jul 1;23(13):i508-18.

PMID:
17646338

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