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Items: 47


Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness.

Sharma A, Oonthonpan L, Sheldon RD, Rauckhorst AJ, Zhu Z, Tompkins SC, Cho K, Grzesik WJ, Gray LR, Scerbo DA, Pewa AD, Cushing EM, Dyle MC, Cox JE, Adams C, Davies BS, Shields RK, Norris AW, Patti G, Zingman LV, Taylor EB.

Elife. 2019 Jul 18;8. pii: e45873. doi: 10.7554/eLife.45873.


Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4.

Kolb R, Kluz P, Tan ZW, Borcherding N, Bormann N, Vishwakarma A, Balcziak L, Zhu P, Davies BS, Gourronc F, Liu LZ, Ge X, Jiang BH, Gibson-Corley K, Klingelhutz A, Tan NS, Zhu Y, Sutterwala FS, Shen X, Zhang W.

Oncogene. 2019 Mar;38(13):2351-2363. doi: 10.1038/s41388-018-0592-6. Epub 2018 Dec 5.


The role of the smartphone in the transition from medical student to foundation trainee: a qualitative interview and focus group study.

Shenouda JEA, Davies BS, Haq I.

BMC Med Educ. 2018 Jul 31;18(1):175. doi: 10.1186/s12909-018-1279-y.


Novel GPIHBP1-independent pathway for clearance of plasma TGs in Angptl4-/-Gpihbp1-/- mice.

Cushing EM, Sylvers KL, Chi X, Shetty SK, Davies BSJ.

J Lipid Res. 2018 Jul;59(7):1230-1243. doi: 10.1194/jlr.M084749. Epub 2018 May 8.


Can targeting ANGPTL proteins improve glucose tolerance?

Davies BSJ.

Diabetologia. 2018 Jun;61(6):1277-1281. doi: 10.1007/s00125-018-4604-4. Epub 2018 Apr 4.


ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase.

Chi X, Britt EC, Shows HW, Hjelmaas AJ, Shetty SK, Cushing EM, Li W, Dou A, Zhang R, Davies BSJ.

Mol Metab. 2017 Oct;6(10):1137-1149. doi: 10.1016/j.molmet.2017.06.014. Epub 2017 Jun 29.


Angiopoietin-like 4 directs uptake of dietary fat away from adipose during fasting.

Cushing EM, Chi X, Sylvers KL, Shetty SK, Potthoff MJ, Davies BSJ.

Mol Metab. 2017 Jun 19;6(8):809-818. doi: 10.1016/j.molmet.2017.06.007. eCollection 2017 Aug.


Angiopoietin-like 4 Modifies the Interactions between Lipoprotein Lipase and Its Endothelial Cell Transporter GPIHBP1.

Chi X, Shetty SK, Shows HW, Hjelmaas AJ, Malcolm EK, Davies BS.

J Biol Chem. 2015 May 8;290(19):11865-77. doi: 10.1074/jbc.M114.623769. Epub 2015 Mar 25.


GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.

Beigneux AP, Fong LG, Bensadoun A, Davies BS, Oberer M, Gårdsvoll H, Ploug M, Young SG.

Circ Res. 2015 Feb 13;116(4):624-32. doi: 10.1161/CIRCRESAHA.116.305085. Epub 2014 Nov 11.


Targeting protein prenylation in progeria.

Young SG, Yang SH, Davies BS, Jung HJ, Fong LG.

Sci Transl Med. 2013 Feb 6;5(171):171ps3. doi: 10.1126/scitranslmed.3005229. Review.


Non-tuberculous slow-growing mycobacterial pulmonary infections in non-HIV-infected patients in south London.

Davies BS, Roberts CH, Kaul S, Klein JL, Milburn HJ.

Scand J Infect Dis. 2012 Nov;44(11):815-9. doi: 10.3109/00365548.2012.694469.


Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells.

Davies BS, Goulbourne CN, Barnes RH 2nd, Turlo KA, Gin P, Vaughan S, Vaux DJ, Bensadoun A, Beigneux AP, Fong LG, Young SG.

J Lipid Res. 2012 Dec;53(12):2690-7. doi: 10.1194/jlr.M031559. Epub 2012 Sep 24.


Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1.

Gin P, Goulbourne CN, Adeyo O, Beigneux AP, Davies BS, Tat S, Voss CV, Bensadoun A, Fong LG, Young SG.

Hum Mol Genet. 2012 Jul 1;21(13):2961-72. doi: 10.1093/hmg/dds127. Epub 2012 Apr 6.


Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.

Jung HJ, Coffinier C, Choe Y, Beigneux AP, Davies BS, Yang SH, Barnes RH 2nd, Hong J, Sun T, Pleasure SJ, Young SG, Fong LG.

Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):E423-31. doi: 10.1073/pnas.1111780109. Epub 2012 Jan 30.


Mobile Medical Education (MoMEd) - how mobile information resources contribute to learning for undergraduate clinical students - a mixed methods study.

Davies BS, Rafique J, Vincent TR, Fairclough J, Packer MH, Vincent R, Haq I.

BMC Med Educ. 2012 Jan 12;12:1. doi: 10.1186/1472-6920-12-1.


Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice.

Weinstein MM, Goulbourne CN, Davies BS, Tu Y, Barnes RH 2nd, Watkins SM, Davis R, Reue K, Tontonoz P, Beigneux AP, Fong LG, Young SG.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):230-5. doi: 10.1161/ATVBAHA.111.241406. Epub 2011 Dec 15.


New wrinkles in lipoprotein lipase biology.

Davies BS, Beigneux AP, Fong LG, Young SG.

Curr Opin Lipidol. 2012 Feb;23(1):35-42. doi: 10.1097/MOL.0b013e32834d0b33. Review.


GPIHBP1, an endothelial cell transporter for lipoprotein lipase.

Young SG, Davies BS, Voss CV, Gin P, Weinstein MM, Tontonoz P, Reue K, Bensadoun A, Fong LG, Beigneux AP.

J Lipid Res. 2011 Nov;52(11):1869-84. doi: 10.1194/jlr.R018689. Epub 2011 Aug 15. Review.


Investigating the purpose of prelamin A processing.

Davies BS, Coffinier C, Yang SH, Barnes RH 2nd, Jung HJ, Young SG, Fong LG.

Nucleus. 2011 Jan-Feb;2(1):4-9. doi: 10.1093/hmg/ddq158. Review.


Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1.

Voss CV, Davies BS, Tat S, Gin P, Fong LG, Pelletier C, Mottler CD, Bensadoun A, Beigneux AP, Young SG.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7980-4. doi: 10.1073/pnas.1100992108. Epub 2011 Apr 25.


Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase.

Beigneux AP, Davies BS, Tat S, Chen J, Gin P, Voss CV, Weinstein MM, Bensadoun A, Pullinger CR, Fong LG, Young SG.

J Biol Chem. 2011 Jun 3;286(22):19735-43. doi: 10.1074/jbc.M111.242024. Epub 2011 Apr 7.


Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells.

Gin P, Beigneux AP, Voss C, Davies BS, Beckstead JA, Ryan RO, Bensadoun A, Fong LG, Young SG.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):176-82. doi: 10.1161/ATVBAHA.110.214718. Epub 2010 Oct 21.


Unexpected expression pattern for glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) in mouse tissues revealed by positron emission tomography scanning.

Olafsen T, Young SG, Davies BS, Beigneux AP, Kenanova VE, Voss C, Young G, Wong KP, Barnes RH 2nd, Tu Y, Weinstein MM, Nobumori C, Huang SC, Goldberg IJ, Bensadoun A, Wu AM, Fong LG.

J Biol Chem. 2010 Dec 10;285(50):39239-48. doi: 10.1074/jbc.M110.171041. Epub 2010 Sep 30.


Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice.

Weinstein MM, Tu Y, Beigneux AP, Davies BS, Gin P, Voss C, Walzem RL, Reue K, Tontonoz P, Bensadoun A, Fong LG, Young SG.

Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2106-13. doi: 10.1161/ATVBAHA.110.214403. Epub 2010 Sep 2.


GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries.

Davies BS, Beigneux AP, Barnes RH 2nd, Tu Y, Gin P, Weinstein MM, Nobumori C, Nyrén R, Goldberg I, Olivecrona G, Bensadoun A, Young SG, Fong LG.

Cell Metab. 2010 Jul 7;12(1):42-52. doi: 10.1016/j.cmet.2010.04.016.


Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice.

Coffinier C, Jung HJ, Li Z, Nobumori C, Yun UJ, Farber EA, Davies BS, Weinstein MM, Yang SH, Lammerding J, Farahani JN, Bentolila LA, Fong LG, Young SG.

J Biol Chem. 2010 Jul 2;285(27):20818-26. doi: 10.1074/jbc.M110.128835. Epub 2010 May 3.


An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.

Davies BS, Barnes RH 2nd, Tu Y, Ren S, Andres DA, Spielmann HP, Lammerding J, Wang Y, Young SG, Fong LG.

Hum Mol Genet. 2010 Jul 1;19(13):2682-94. doi: 10.1093/hmg/ddq158. Epub 2010 Apr 26.


Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.

Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG.

Hum Mol Genet. 2010 Apr 15;19(8):1603-17. doi: 10.1093/hmg/ddq036. Epub 2010 Jan 27.


Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia.

Olivecrona G, Ehrenborg E, Semb H, Makoveichuk E, Lindberg A, Hayden MR, Gin P, Davies BS, Weinstein MM, Fong LG, Beigneux AP, Young SG, Olivecrona T, Hernell O.

J Lipid Res. 2010 Jun;51(6):1535-45. doi: 10.1194/jlr.M002717. Epub 2009 Dec 21.


A novel approach to tag and identify geranylgeranylated proteins.

Chan LN, Hart C, Guo L, Nyberg T, Davies BS, Fong LG, Young SG, Agnew BJ, Tamanoi F.

Electrophoresis. 2009 Oct;30(20):3598-606. doi: 10.1002/elps.200900259.


Highly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase.

Beigneux AP, Gin P, Davies BS, Weinstein MM, Bensadoun A, Fong LG, Young SG.

J Biol Chem. 2009 Oct 30;284(44):30240-7. doi: 10.1074/jbc.M109.046391. Epub 2009 Sep 2.


The posttranslational processing of prelamin A and disease.

Davies BS, Fong LG, Yang SH, Coffinier C, Young SG.

Annu Rev Genomics Hum Genet. 2009;10:153-74. doi: 10.1146/annurev-genom-082908-150150. Review.


The small molecule phenamil induces osteoblast differentiation and mineralization.

Park KW, Waki H, Kim WK, Davies BS, Young SG, Parhami F, Tontonoz P.

Mol Cell Biol. 2009 Jul;29(14):3905-14. doi: 10.1128/MCB.00002-09. Epub 2009 May 11.


Activating the synthesis of progerin, the mutant prelamin A in Hutchinson-Gilford progeria syndrome, with antisense oligonucleotides.

Fong LG, Vickers TA, Farber EA, Choi C, Yun UJ, Hu Y, Yang SH, Coffinier C, Lee R, Yin L, Davies BS, Andres DA, Spielmann HP, Bennett CF, Young SG.

Hum Mol Genet. 2009 Jul 1;18(13):2462-71. doi: 10.1093/hmg/ddp184. Epub 2009 Apr 17.


GPIHBP1 and lipolysis: an update.

Beigneux AP, Weinstein MM, Davies BS, Gin P, Bensadoun A, Fong LG, Young SG.

Curr Opin Lipidol. 2009 Jun;20(3):211-6. doi: 10.1097/MOL.0b013e32832ac026. Review.


Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase.

Beigneux AP, Franssen R, Bensadoun A, Gin P, Melford K, Peter J, Walzem RL, Weinstein MM, Davies BS, Kuivenhoven JA, Kastelein JJ, Fong LG, Dallinga-Thie GM, Young SG.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):956-62. doi: 10.1161/ATVBAHA.109.186577. Epub 2009 Mar 19.


GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins.

Beigneux AP, Davies BS, Bensadoun A, Fong LG, Young SG.

J Lipid Res. 2009 Apr;50 Suppl:S57-62. doi: 10.1194/jlr.R800030-JLR200. Epub 2008 Oct 14. Review.


Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice.

Weinstein MM, Yin L, Beigneux AP, Davies BS, Gin P, Estrada K, Melford K, Bishop JR, Esko JD, Dallinga-Thie GM, Fong LG, Bensadoun A, Young SG.

J Biol Chem. 2008 Dec 12;283(50):34511-8. doi: 10.1074/jbc.M806067200. Epub 2008 Oct 8. Erratum in: J Biol Chem. 2009 Feb 6;284(6):4040.


The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma.

Davies BS, Waki H, Beigneux AP, Farber E, Weinstein MM, Wilpitz DC, Tai LJ, Evans RM, Fong LG, Tontonoz P, Young SG.

Mol Endocrinol. 2008 Nov;22(11):2496-504. doi: 10.1210/me.2008-0146. Epub 2008 Sep 11. Erratum in: Mol Endocrinol. 2008 Dec;22(12):2766.


Increasing the length of progerin's isoprenyl anchor does not worsen bone disease or survival in mice with Hutchinson-Gilford progeria syndrome.

Davies BS, Yang SH, Farber E, Lee R, Buck SB, Andres DA, Spielmann HP, Agnew BJ, Tamanoi F, Fong LG, Young SG.

J Lipid Res. 2009 Jan;50(1):126-34. doi: 10.1194/jlr.M800424-JLR200. Epub 2008 Aug 29.


The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.

Gin P, Yin L, Davies BS, Weinstein MM, Ryan RO, Bensadoun A, Fong LG, Young SG, Beigneux AP.

J Biol Chem. 2008 Oct 24;283(43):29554-62. doi: 10.1074/jbc.M802579200. Epub 2008 Aug 18.


Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase.

Beigneux AP, Gin P, Davies BS, Weinstein MM, Bensadoun A, Ryan RO, Fong LG, Young SG.

J Lipid Res. 2008 Jun;49(6):1312-21. doi: 10.1194/jlr.M700593-JLR200. Epub 2008 Mar 13.


GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons.

Young SG, Davies BS, Fong LG, Gin P, Weinstein MM, Bensadoun A, Beigneux AP.

Curr Opin Lipidol. 2007 Aug;18(4):389-96. Review.


Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons.

Beigneux AP, Davies BS, Gin P, Weinstein MM, Farber E, Qiao X, Peale F, Bunting S, Walzem RL, Wong JS, Blaner WS, Ding ZM, Melford K, Wongsiriroj N, Shu X, de Sauvage F, Ryan RO, Fong LG, Bensadoun A, Young SG.

Cell Metab. 2007 Apr;5(4):279-91.


A role for sterol levels in oxygen sensing in Saccharomyces cerevisiae.

Davies BS, Rine J.

Genetics. 2006 Sep;174(1):191-201. Epub 2006 Jun 18.


The pattern of haemolytic disease of the newborn.


Arch Dis Child. 1953 Dec;28(142):466-70. No abstract available.

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