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Items: 1 to 50 of 397

1.

Gene therapy matures to medicines.

Davidson BL, Arruda VR.

Hum Mol Genet. 2019 Sep 6. pii: ddz182. doi: 10.1093/hmg/ddz182. [Epub ahead of print] No abstract available.

PMID:
31595292
2.

Neuronal network dysfunction precedes storage and neurodegeneration in a lysosomal storage disorder.

Ahrens-Nicklas RC, Tecedor L, Hall A, Lysenko E, Cohen AS, Davidson BL, Marsh ED.

JCI Insight. 2019 Oct 1. pii: 131961. doi: 10.1172/jci.insight.131961. [Epub ahead of print]

3.

Doubling down on siRNAs in the brain.

Davidson BL.

Nat Biotechnol. 2019 Aug;37(8):865-866. doi: 10.1038/s41587-019-0204-1. No abstract available.

PMID:
31375811
4.

Standard screening methods underreport AAV-mediated transduction and gene editing.

Lang JF, Toulmin SA, Brida KL, Eisenlohr LC, Davidson BL.

Nat Commun. 2019 Jul 30;10(1):3415. doi: 10.1038/s41467-019-11321-7.

5.

Thromboprophylaxis by rivaroxaban, aspirin, both, or placebo after hospitalization for medical illness.

Tomkowski WZ, Davidson BL.

Thromb Res. 2019 Aug;180:62-63. doi: 10.1016/j.thromres.2019.06.002. Epub 2019 Jun 11. No abstract available.

PMID:
31226663
6.

Publisher Correction: Lysosomal storage diseases.

Platt FM, d'Azzo A, Davidson BL, Neufeld EF, Tifft CJ.

Nat Rev Dis Primers. 2019 May 17;5(1):34. doi: 10.1038/s41572-019-0089-9.

PMID:
31101820
7.

Extended anticoagulant therapy in venous thromboembolism: a balanced, fractional factorial, clinical vignette-based study.

Cate VT, Lensing AWA, Weitz JI, Beyer-Westendorf J, Wells PS, Mismetti P, Prandoni P, Cohen AT, Davidson BL, Prins MH.

Haematologica. 2019 Oct;104(10):e474-e477. doi: 10.3324/haematol.2018.209924. Epub 2019 Mar 7. No abstract available.

8.

Monoclonal Antibody Treatment of RSV Bronchiolitis in Young Infants: A Randomized Trial.

Alansari K, Toaimah FH, Almatar DH, El Tatawy LA, Davidson BL, Qusad MIM.

Pediatrics. 2019 Mar;143(3). pii: e20182308. doi: 10.1542/peds.2018-2308. Epub 2019 Feb 13.

PMID:
30760509
9.

CRISPR to the Rescue: Advances in Gene Editing for the FMR1 Gene.

Yrigollen CM, Davidson BL.

Brain Sci. 2019 Jan 21;9(1). pii: E17. doi: 10.3390/brainsci9010017. Review.

10.

Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene.

Maguire JA, Gagne AL, Gonzalez-Alegre P, Davidson BL, Shakkottai V, Gadue P, French DL.

Stem Cell Res. 2019 Jan;34:101361. doi: 10.1016/j.scr.2018.101361. Epub 2018 Dec 10.

11.

AAV-Mediated Progranulin Delivery to a Mouse Model of Progranulin Deficiency Causes T Cell-Mediated Toxicity.

Amado DA, Rieders JM, Diatta F, Hernandez-Con P, Singer A, Mak JT, Zhang J, Lancaster E, Davidson BL, Chen-Plotkin AS.

Mol Ther. 2019 Feb 6;27(2):465-478. doi: 10.1016/j.ymthe.2018.11.013. Epub 2018 Nov 17.

PMID:
30559071
12.

Adeno-Associated Virus Production, Purification, and Titering.

Chen YH, Keiser MS, Davidson BL.

Curr Protoc Mouse Biol. 2018 Dec;8(4):e56. doi: 10.1002/cpmo.56. Epub 2018 Nov 29.

PMID:
30489697
13.

Viral Vectors for Gene Transfer.

Chen YH, Keiser MS, Davidson BL.

Curr Protoc Mouse Biol. 2018 Dec;8(4):e58. doi: 10.1002/cpmo.58. Epub 2018 Nov 28. Review.

PMID:
30485696
14.

Techniques for Intracranial Stereotaxic Injections of Adeno-Associated Viral Vectors in Adult Mice.

Keiser MS, Chen YH, Davidson BL.

Curr Protoc Mouse Biol. 2018 Dec;8(4):e57. doi: 10.1002/cpmo.57. Epub 2018 Nov 5.

PMID:
30395418
15.

Author Correction: Lysosomal storage diseases.

Platt FM, d'Azzo A, Davidson BL, Neufeld EF, Tifft CJ.

Nat Rev Dis Primers. 2018 Oct 18;4(1):36. doi: 10.1038/s41572-018-0037-0.

PMID:
30337566
16.

Lysosomal storage diseases.

Platt FM, d'Azzo A, Davidson BL, Neufeld EF, Tifft CJ.

Nat Rev Dis Primers. 2018 Oct 1;4(1):27. doi: 10.1038/s41572-018-0025-4. Review. Erratum in: Nat Rev Dis Primers. 2018 Oct 18;4(1):36. Nat Rev Dis Primers. 2019 May 17;5(1):34.

PMID:
30275469
17.

The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities.

Cheng C, Spengler RM, Keiser MS, Monteys AM, Rieders JM, Ramachandran S, Davidson BL.

Hum Mol Genet. 2018 Dec 15;27(24):4303-4314. doi: 10.1093/hmg/ddy331.

18.

Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries.

Sun JH, Zhou L, Emerson DJ, Phyo SA, Titus KR, Gong W, Gilgenast TG, Beagan JA, Davidson BL, Tassone F, Phillips-Cremins JE.

Cell. 2018 Sep 20;175(1):224-238.e15. doi: 10.1016/j.cell.2018.08.005. Epub 2018 Aug 30.

19.

Benefits and risks of extended treatment of venous thromboembolism with rivaroxaban or with aspirin.

Prandoni P, Lensing AWA, Prins MH, Gebel M, Pap AF, Homering M, Bauersachs R, Beyer-Westendorf J, Bounameaux H, Cohen AT, Davidson BL, van Bellen B, Verhamme P, Wells PS, Yuan Z, Levitan B, Weitz JI.

Thromb Res. 2018 Aug;168:121-129. doi: 10.1016/j.thromres.2018.06.009. Epub 2018 Jul 10.

PMID:
30064683
20.

Administration of placebo vitamin D to non-consenting children.

Davidson BL.

Lancet Respir Med. 2018 Jun;6(6):e23-e24. doi: 10.1016/S2213-2600(18)30198-X. No abstract available.

PMID:
29856325
21.

Cardiac mTORC1 Dysregulation Impacts Stress Adaptation and Survival in Huntington's Disease.

Child DD, Lee JH, Pascua CJ, Chen YH, Mas Monteys A, Davidson BL.

Cell Rep. 2018 Apr 24;23(4):1020-1033. doi: 10.1016/j.celrep.2018.03.117.

22.

Modulating membrane fluidity corrects Batten disease phenotypes in vitro and in vivo.

Schultz ML, Tecedor L, Lysenko E, Ramachandran S, Stein CS, Davidson BL.

Neurobiol Dis. 2018 Jul;115:182-193. doi: 10.1016/j.nbd.2018.04.010. Epub 2018 Apr 13.

23.

Risk of recurrent venous thromboembolism according to baseline risk factor profiles.

Prins MH, Lensing AWA, Prandoni P, Wells PS, Verhamme P, Beyer-Westendorf J, Bauersachs R, Bounameaux H, Brighton TA, Cohen AT, Davidson BL, Decousus H, Kakkar AK, van Bellen B, Pap AF, Homering M, Tamm M, Weitz JI.

Blood Adv. 2018 Apr 10;2(7):788-796. doi: 10.1182/bloodadvances.2018017160.

24.

Vitamin D deficiency can impair respiratory health.

Davidson BL, Alansari K.

Respirology. 2018 Jun;23(6):554-555. doi: 10.1111/resp.13290. Epub 2018 Mar 12. No abstract available.

25.

Overcoming Limitations Inherent in Sulfamidase to Improve Mucopolysaccharidosis IIIA Gene Therapy.

Chen Y, Zheng S, Tecedor L, Davidson BL.

Mol Ther. 2018 Apr 4;26(4):1118-1126. doi: 10.1016/j.ymthe.2018.01.010. Epub 2018 Jan 31.

26.

Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes.

Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS.

Nat Neurosci. 2018 Mar;21(3):341-352. doi: 10.1038/s41593-018-0075-7. Epub 2018 Feb 5.

27.

Vitamin D Supplementation and Upper Respiratory Tract Infections in Children.

Davidson BL, Alansari K.

JAMA. 2017 Dec 5;318(21):2138-2139. doi: 10.1001/jama.2017.15150. No abstract available.

PMID:
29209712
28.

Response.

Alansari K, Davidson BL.

Chest. 2017 Nov;152(5):1094. doi: 10.1016/j.chest.2017.08.1164. No abstract available.

PMID:
29126528
29.

Rapid vs Maintenance Vitamin D Supplementation in Deficient Children With Asthma to Prevent Exacerbations.

Alansari K, Davidson BL, Yousef KI, Mohamed ANH, Alattar I.

Chest. 2017 Sep;152(3):527-536. doi: 10.1016/j.chest.2017.06.021. Epub 2017 Jun 23.

PMID:
28651793
30.

Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism.

Weitz JI, Lensing AWA, Prins MH, Bauersachs R, Beyer-Westendorf J, Bounameaux H, Brighton TA, Cohen AT, Davidson BL, Decousus H, Freitas MCS, Holberg G, Kakkar AK, Haskell L, van Bellen B, Pap AF, Berkowitz SD, Verhamme P, Wells PS, Prandoni P; EINSTEIN CHOICE Investigators.

N Engl J Med. 2017 Mar 30;376(13):1211-1222. doi: 10.1056/NEJMoa1700518. Epub 2017 Mar 18.

31.

IV Magnesium Sulfate for Bronchiolitis: A Randomized Trial.

Alansari K, Sayyed R, Davidson BL, Al Jawala S, Ghadier M.

Chest. 2017 Jul;152(1):113-119. doi: 10.1016/j.chest.2017.03.002. Epub 2017 Mar 9.

PMID:
28286262
32.

Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease.

Carmona V, Cunha-Santos J, Onofre I, Simões AT, Vijayakumar U, Davidson BL, Pereira de Almeida L.

Mol Ther. 2017 Apr 5;25(4):1038-1055. doi: 10.1016/j.ymthe.2017.01.021. Epub 2017 Feb 22.

33.

RNA Interference of Human α-Synuclein in Mouse.

Kim YC, Miller A, Lins LC, Han SW, Keiser MS, Boudreau RL, Davidson BL, Narayanan NS.

Front Neurol. 2017 Jan 31;8:13. doi: 10.3389/fneur.2017.00013. eCollection 2017.

34.

Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts.

Ramachandran S, Coffin SL, Tang TY, Jobaliya CD, Spengler RM, Davidson BL.

Hum Mol Genet. 2016 Nov 15;25(22):4939-4950. doi: 10.1093/hmg/ddw317.

35.

CRISPR/Cas9 Editing of the Mutant Huntingtin Allele In Vitro and In Vivo.

Monteys AM, Ebanks SA, Keiser MS, Davidson BL.

Mol Ther. 2017 Jan 4;25(1):12-23. doi: 10.1016/j.ymthe.2016.11.010. Epub 2017 Jan 4.

36.

Safety and Efficacy of Ex Vivo Donor Lung Adenoviral IL-10 Gene Therapy in a Large Animal Lung Transplant Survival Model.

Machuca TN, Cypel M, Bonato R, Yeung JC, Chun YM, Juvet S, Guan Z, Hwang DM, Chen M, Saito T, Harmantas C, Davidson BL, Waddell TK, Liu M, Keshavjee S.

Hum Gene Ther. 2017 Sep;28(9):757-765. doi: 10.1089/hum.2016.070. Epub 2017 Jan 4.

PMID:
28052693
37.

Reducing Procedural Hemorrhage Risk.

Davidson BL.

Chest. 2016 Dec;150(6):1421. doi: 10.1016/j.chest.2016.10.033. No abstract available.

PMID:
27938761
38.

Engineering a gene silencing viral construct that targets the cat hypothalamus to induce permanent sterility: An update.

Dissen GA, Adachi K, Lomniczi A, Chatkupt T, Davidson BL, Nakai H, Ojeda SR.

Reprod Domest Anim. 2017 Apr;52 Suppl 2:354-358. doi: 10.1111/rda.12834. Epub 2016 Nov 17.

39.

RNAi prevents and reverses phenotypes induced by mutant human ataxin-1.

Keiser MS, Monteys AM, Corbau R, Gonzalez-Alegre P, Davidson BL.

Ann Neurol. 2016 Nov;80(5):754-765. doi: 10.1002/ana.24789. Epub 2016 Nov 2.

40.

The use of disposable skin staples for intestinal resection and anastomosis in 63 dogs: 2000 to 2014.

Rosenbaum JM, Coolman BR, Davidson BL, Daly ML, Rexing JF, Eatroff AE.

J Small Anim Pract. 2016 Nov;57(11):631-636. doi: 10.1111/jsap.12584. Epub 2016 Oct 5.

PMID:
27709619
41.

Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP.

Spengler RM, Zhang X, Cheng C, McLendon JM, Skeie JM, Johnson FL, Davidson BL, Boudreau RL.

Nucleic Acids Res. 2016 Sep 6;44(15):7120-31. doi: 10.1093/nar/gkw640. Epub 2016 Jul 14.

42.

Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.

Lin L, Park JW, Ramachandran S, Zhang Y, Tseng YT, Shen S, Waldvogel HJ, Curtis MA, Faull RL, Troncoso JC, Pletnikova O, Ross CA, Davidson BL, Xing Y.

Hum Mol Genet. 2016 Aug 15;25(16):3454-3466. doi: 10.1093/hmg/ddw187. Epub 2016 Jul 4.

43.

Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH.

Martin K, Beyer-Westendorf J, Davidson BL, Huisman MV, Sandset PM, Moll S.

J Thromb Haemost. 2016 Jun;14(6):1308-13. doi: 10.1111/jth.13323. Epub 2016 Apr 27. Review. No abstract available.

44.

Long-term Anticoagulation With Rivaroxaban for Preventing Recurrent VTE: A Benefit-Risk Analysis of EINSTEIN-Extension.

Wells PS, Prins MH, Levitan B, Beyer-Westendorf J, Brighton TA, Bounameaux H, Cohen AT, Davidson BL, Prandoni P, Raskob GE, Yuan Z, Katz EG, Gebel M, Lensing AWA.

Chest. 2016 Nov;150(5):1059-1068. doi: 10.1016/j.chest.2016.05.023. Epub 2016 Jun 1.

PMID:
27262225
45.

Caffeine for the Treatment of Apnea in Bronchiolitis: A Randomized Trial.

Alansari K, Toaimah FH, Khalafalla H, El Tatawy LA, Davidson BL, Ahmed W.

J Pediatr. 2016 Oct;177:204-211.e3. doi: 10.1016/j.jpeds.2016.04.060. Epub 2016 May 14.

PMID:
27189681
46.

PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.

Ochaba J, Monteys AM, O'Rourke JG, Reidling JC, Steffan JS, Davidson BL, Thompson LM.

Neuron. 2016 May 4;90(3):507-20. doi: 10.1016/j.neuron.2016.03.016. Epub 2016 Apr 14.

47.

Gene therapy grows up (and moves out of the house).

Davidson BL, Lee B.

Hum Mol Genet. 2016 Apr 15;25(R1):R1. doi: 10.1093/hmg/ddw060. No abstract available.

PMID:
27001078
48.

Rebuttal From Dr Davidson.

Davidson BL.

Chest. 2016 Mar;149(3):628-9. doi: 10.1016/j.chest.2015.11.029. No abstract available.

PMID:
26965969
49.

POINT: Does the United States Need More Intensivist Physicians? Yes.

Davidson BL.

Chest. 2016 Mar;149(3):621-5. doi: 10.1016/j.chest.2015.11.030. No abstract available.

PMID:
26965967
50.

AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease.

Katz ML, Tecedor L, Chen Y, Williamson BG, Lysenko E, Wininger FA, Young WM, Johnson GC, Whiting RE, Coates JR, Davidson BL.

Sci Transl Med. 2015 Nov 11;7(313):313ra180. doi: 10.1126/scitranslmed.aac6191.

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