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A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma.

Furman WL, Federico SM, McCarville MB, Shulkin BL, Davidoff AM, Krasin MJ, Sahr N, Sykes A, Wu J, Brennan RC, Bishop MW, Helmig S, Stewart E, Navid F, Triplett B, Santana VM, Bahrami A, Anthony G, Yu AL, Hank J, Gillies SD, Sondel PM, Leung WH, Pappo AS.

Clin Cancer Res. 2019 Oct 10. doi: 10.1158/1078-0432.CCR-19-1452. [Epub ahead of print]


Minimally Invasive Surgery in Pediatric Surgical Oncology: Practice Evolution at a Contemporary Single-Center Institution and a Guideline Proposal for a Randomized Controlled Study.

Abdelhafeez A, Ortega-Laureano L, Murphy AJ, Davidoff AM, Fernandez-Pineda I, Sandoval JA.

J Laparoendosc Adv Surg Tech A. 2019 Aug;29(8):1046-1051. doi: 10.1089/lap.2018.0467. Epub 2019 Jun 25.


Acute Chest Syndrome After Splenectomy in Children With Sickle Cell Disease.

El-Gohary Y, Fleming A, Zhang H, Estepp JH, Hankins JS, Wang W, Davidoff AM, Murphy AJ.

J Surg Res. 2019 Oct;242:336-341. doi: 10.1016/j.jss.2019.04.077. Epub 2019 May 23.


Dedifferentiation in SDH-Deficient Gastrointestinal Stromal Tumor: A Report With Histologic, Immunophenotypic, and Molecular Characterization.

Malik F, Santiago T, Bahrami A, Davis E, McCarville B, Newman S, Azzato EM, Davidoff AM, Brennan R, Ellison DW, Clay MR.

Pediatr Dev Pathol. 2019 Oct;22(5):492-498. doi: 10.1177/1093526619846222. Epub 2019 May 9.


Role of the extent of prophylactic regional lymph node radiotherapy on survival in high-risk neuroblastoma: A report from the COG A3973 study.

Braunstein SE, London WB, Kreissman SG, Villablanca JG, Davidoff AM, DeSantes K, Castleberry RP, Murray K, Diller L, Matthay K, Cohn SL, Shulkin B, von Allmen D, Parisi MT, Van Ryn C, Park JR, La Quaglia MP, Haas-Kogan DA.

Pediatr Blood Cancer. 2019 Jul;66(7):e27736. doi: 10.1002/pbc.27736. Epub 2019 Apr 9.


Desmoplastic Small Round Cell Tumor: Long-Term Complications After Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy.

Stiles ZE, Murphy AJ, Anghelescu DL, Brown CL, Davidoff AM, Dickson PV, Glazer ES, Bishop MW, Furman WL, Pappo AS, Lucas JT Jr, Deneve JL.

Ann Surg Oncol. 2019 Apr 8. doi: 10.1245/s10434-019-07339-2. [Epub ahead of print]


Neutropenia at the time of subcutaneous port insertion may not be a risk factor for early infectious complications in pediatric oncology patients.

VanHouwelingen LT, Veras LV, Lu M, Wynn L, Wu J, Prajapati HJ, Gold RE, Murphy AJ, Fernandez-Pineda I, Gosain A, Pui CH, Davidoff AM.

J Pediatr Surg. 2019 Jan;54(1):145-149. doi: 10.1016/j.jpedsurg.2018.10.024. Epub 2018 Oct 5.


Implications of Image-Defined Risk Factors and Primary-Site Response on Local Control and Radiation Treatment Delivery in the Management of High-Risk Neuroblastoma: Is There a Role for De-escalation of Adjuvant Primary-Site Radiation Therapy?

Lucas JT Jr, McCarville MB, Cooper DA, Doubrovin M, Wakefield D, Santiago T, Li Y, Li X, Krasin M, Santana V, Furman W, Davidoff AM.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):869-877. doi: 10.1016/j.ijrobp.2018.11.041. Epub 2018 Nov 26.


Modified Uniportal Video-Assisted Thoracic Surgery Versus Three-Port Approach for Lung Nodule Biopsy in Pediatric Cancer Patients.

Fernandez-Pineda I, Seims AD, VanHouwelingen L, Abdelhafeez H, Wu H, Wu J, Murphy AJ, Davidoff AM.

J Laparoendosc Adv Surg Tech A. 2019 Mar;29(3):409-414. doi: 10.1089/lap.2018.0120. Epub 2018 Nov 10.


KDM5A Regulates a Translational Program that Controls p53 Protein Expression.

Hu D, Jablonowski C, Cheng PH, AlTahan A, Li C, Wang Y, Palmer L, Lan C, Sun B, Abu-Zaid A, Fan Y, Brimble M, Gamboa NT, Kumbhar RC, Yanishevski D, Miller KM, Kang G, Zambetti GP, Chen T, Yan Q, Davidoff AM, Yang J.

iScience. 2018 Nov 30;9:84-100. doi: 10.1016/j.isci.2018.10.012. Epub 2018 Oct 17.


Anesthesia and Pain Management for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Desmoplastic Small Round Cell Tumors in Children, Adolescents, and Young Adults.

Anghelescu DL, Brown CL, Murphy AJ, Davidoff AM, Dickson PV, Glazer ES, Stiles ZE, Bishop MW, Douthitt L, Deneve JL.

Ann Surg Oncol. 2019 Jan;26(1):131-138. doi: 10.1245/s10434-018-6808-8. Epub 2018 Oct 23.


Managing local-regional failure in children with high-risk neuroblastoma: A single institution experience.

Dove AP, Manole BA, Wakefield DV, Cross SJ, Doubrovin M, Shulkin BL, Merchant TE, Davidoff AM, Furman WL, Krasin MJ, Santana VM, Lucas JT Jr.

Pediatr Blood Cancer. 2018 Dec;65(12):e27408. doi: 10.1002/pbc.27408. Epub 2018 Sep 30.


Bilateral Wilms Tumor: A Surgical Perspective.

Murphy AJ, Davidoff AM.

Children (Basel). 2018 Sep 24;5(10). pii: E134. doi: 10.3390/children5100134. Review.


Outcome and factors associated with aborted cytoreduction for peritoneal carcinomatosis.

Guerrero W, Munene G, Dickson PV, Stiles ZE, Mays J, Davidoff AM, Glazer ES, Shibata D, Deneve JL.

J Gastrointest Oncol. 2018 Aug;9(4):664-673. doi: 10.21037/jgo.2018.04.05.


Is there a role for salvage re-irradiation in pediatric patients with locoregional recurrent rhabdomyosarcoma? Clinical outcomes from a multi-institutional cohort.

Wakefield DV, Eaton BR, Dove APH, Hsu CY, Merchant TE, Pappo A, Davidoff AM, Esiashvili N, Krasin MJ, Lucas JT Jr.

Radiother Oncol. 2018 Dec;129(3):513-519. doi: 10.1016/j.radonc.2018.06.041. Epub 2018 Jul 14.


The Impact of Ostomy Creation after Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy in a Newly Established Peritoneal Malignancy Program.

Stiles ZE, Hinkle NM, Munene G, Dickson PV, Davidoff AM, Deneve JL.

Am Surg. 2018 Jun 1;84(6):776-782.


Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines.

Feng H, Tillman H, Wu G, Davidoff AM, Yang J.

Oncotarget. 2018 Jun 5;9(43):27087-27091. doi: 10.18632/oncotarget.25484. eCollection 2018 Jun 5.


Desmoplastic small round cell tumor: A nationwide study of a rare sarcoma.

Stiles ZE, Dickson PV, Glazer ES, Murphy AJ, Davidoff AM, Behrman SW, Bishop MW, Martin MG, Deneve JL.

J Surg Oncol. 2018 Jun;117(8):1759-1767. doi: 10.1002/jso.25071. Epub 2018 Jun 7.


Early experience with cytoreduction and hyperthermic intraperitoneal chemotherapy at a newly developed center for peritoneal malignancy.

Guerrero WL, Munene G, Dickson PV, Darby D, Davidoff AM, Martin MG, Glazer ES, Shibata D, Deneve JL.

J Gastrointest Oncol. 2018 Apr;9(2):338-347. doi: 10.21037/jgo.2018.01.02.


Impact of ovarian transposition before pelvic irradiation on ovarian function among long-term survivors of childhood Hodgkin lymphoma: A report from the St. Jude Lifetime Cohort Study.

Fernandez-Pineda I, Davidoff AM, Lu L, Rao BN, Wilson CL, Srivastava DK, Klosky JL, Metzger ML, Krasin MJ, Ness KK, Pui CH, Robison LL, Hudson MM, Sklar CA, Green DM, Chemaitilly W.

Pediatr Blood Cancer. 2018 Sep;65(9):e27232. doi: 10.1002/pbc.27232. Epub 2018 May 11.


Surgical lung biopsy in children after hematopoietic cell transplantation.

Ortega-Laureano L, Santiago T, Maron G, Davidoff AM, Fernandez-Pineda I.

J Pediatr Surg. 2018 Jun;53(6):1129-1133. doi: 10.1016/j.jpedsurg.2018.02.069. Epub 2018 Mar 6.


MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent.

Wang T, Liu L, Chen X, Shen Y, Lian G, Shah N, Davidoff AM, Yang J, Wang R.

Cell Death Dis. 2018 Feb 14;9(2):220. doi: 10.1038/s41419-018-0295-5.


Learning and Age-Related Changes in Genome-wide H2A.Z Binding in the Mouse Hippocampus.

Stefanelli G, Azam AB, Walters BJ, Brimble MA, Gettens CP, Bouchard-Cannon P, Cheng HM, Davidoff AM, Narkaj K, Day JJ, Kennedy AJ, Zovkic IB.

Cell Rep. 2018 Jan 30;22(5):1124-1131. doi: 10.1016/j.celrep.2018.01.020.


Hypoxia and Hormone-Mediated Pathways Converge at the Histone Demethylase KDM4B in Cancer.

Yang J, Harris AL, Davidoff AM.

Int J Mol Sci. 2018 Jan 13;19(1). pii: E240. doi: 10.3390/ijms19010240. Review.


Use of ultrasound in diagnosing postoperative small-bowel intussusception in pediatric surgical oncology patients: a single-center retrospective review.

VanHouwelingen LT, Seims AD, Ortega-Laureano L, Coleman JL, McCarville MB, Davidoff AM, Fernandez-Pineda I.

Pediatr Radiol. 2018 Feb;48(2):204-209. doi: 10.1007/s00247-017-4018-3. Epub 2017 Oct 30.


Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.

Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA.

Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25.


Gene Therapy for Hemophilia.

Nathwani AC, Davidoff AM, Tuddenham EGD.

Hematol Oncol Clin North Am. 2017 Oct;31(5):853-868. doi: 10.1016/j.hoc.2017.06.011. Review.


Advances in Gene Therapy for Hemophilia.

Nathwani AC, Davidoff AM, Tuddenham EGD.

Hum Gene Ther. 2017 Nov;28(11):1004-1012. doi: 10.1089/hum.2017.167. Review.


An ROR1 bi-specific T-cell engager provides effective targeting and cytotoxicity against a range of solid tumors.

Gohil SH, Paredes-Moscosso SR, Harrasser M, Vezzalini M, Scarpa A, Morris E, Davidoff AM, Sorio C, Nathwani AC, Della Peruta M.

Oncoimmunology. 2017 May 17;6(7):e1326437. doi: 10.1080/2162402X.2017.1326437. eCollection 2017.


RIG-I and IL-6 are negative-feedback regulators of STING induced by double-stranded DNA.

Wu X, Yang J, Na T, Zhang K, Davidoff AM, Yuan BZ, Wang Y.

PLoS One. 2017 Aug 14;12(8):e0182961. doi: 10.1371/journal.pone.0182961. eCollection 2017.


The effects of type I interferon on glioblastoma cancer stem cells.

Du Z, Cai C, Sims M, Boop FA, Davidoff AM, Pfeffer LM.

Biochem Biophys Res Commun. 2017 Sep 16;491(2):343-348. doi: 10.1016/j.bbrc.2017.07.098. Epub 2017 Jul 18.


Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.

Yang J, Milasta S, Hu D, AlTahan AM, Interiano RB, Zhou J, Davidson J, Low J, Lin W, Bao J, Goh P, Nathwani AC, Wang R, Wang Y, Ong SS, Boyd VA, Young B, Das S, Shelat A, Wu Y, Li Z, Zheng JJ, Mishra A, Cheng Y, Qu C, Peng J, Green DR, White S, Guy RK, Chen T, Davidoff AM.

Cancer Res. 2017 Sep 1;77(17):4626-4638. doi: 10.1158/0008-5472.CAN-16-0826. Epub 2017 Jul 6.


Late toxicity and outcomes following radiation therapy for chest wall sarcomas in pediatric patients.

Lucas JT Jr, Fernandez-Pineda I, Tinkle CL, Bishop MW, Kaste SC, Heda R, Davidoff AM, Krasin MJ.

Pract Radiat Oncol. 2017 Nov - Dec;7(6):411-417. doi: 10.1016/j.prro.2017.04.015. Epub 2017 Apr 26.


Associations between treatment, scoliosis, pulmonary function, and physical performance in long-term survivors of sarcoma.

Interiano RB, Kaste SC, Li C, Srivastava DK, Rao BN, Warner WC Jr, Green DM, Krasin MJ, Robison LL, Davidoff AM, Hudson MM, Fernandez-Pineda I, Ness KK.

J Cancer Surviv. 2017 Oct;11(5):553-561. doi: 10.1007/s11764-017-0624-1. Epub 2017 Jul 1.


Outcomes of a pediatric surgical oncology fellowship in a pediatric cancer institution.

Fernandez-Pineda I, Sanders D, Rao BN, Shochat SJ, Davidoff AM.

Pediatr Blood Cancer. 2017 Oct;64(10). doi: 10.1002/pbc.26618. Epub 2017 May 5.


Gene Therapy for Hemophilia.

Nienhuis AW, Nathwani AC, Davidoff AM.

Mol Ther. 2017 May 3;25(5):1163-1167. doi: 10.1016/j.ymthe.2017.03.033. Epub 2017 Apr 11. Review.


Histone demethylases and their roles in cancer epigenetics.

D'Oto A, Tian QW, Davidoff AM, Yang J.

J Med Oncol Ther. 2016;1(2):34-40.


Operative and Immediate Postoperative Differences Between Traditional Multiport and Reduced Port Laparoscopic Total Splenectomy in Pediatric Patients.

Seims AD, VanHouwelingen L, Mead J, Mao S, Loh A, Sandoval JA, Davidoff AM, Wu J, Wang WC, Fernandez-Pineda I.

J Laparoendosc Adv Surg Tech A. 2017 Feb;27(2):206-210. doi: 10.1089/lap.2016.0309. Epub 2016 Oct 24.


Complications in the surgical management of children with malignant solid tumors.

Davidoff AM, Fernandez-Pineda I.

Semin Pediatr Surg. 2016 Dec;25(6):395-403. doi: 10.1053/j.sempedsurg.2016.10.003. Epub 2016 Oct 31. Review.


Surgical treatment of pulmonary metastases in pediatric solid tumors.

Heaton TE, Davidoff AM.

Semin Pediatr Surg. 2016 Oct;25(5):311-317. doi: 10.1053/j.sempedsurg.2016.09.001. Epub 2016 Sep 3. Review.


Dynamics of antigen presentation to transgene product-specific CD4+ T cells and of Treg induction upon hepatic AAV gene transfer.

Perrin GQ, Zolotukhin I, Sherman A, Biswas M, de Jong YP, Terhorst C, Davidoff AM, Herzog RW.

Mol Ther Methods Clin Dev. 2016 Dec 7;3:16083. eCollection 2016.


Impact of Extent of Resection on Local Control and Survival in Patients From the COG A3973 Study With High-Risk Neuroblastoma.

von Allmen D, Davidoff AM, London WB, Van Ryn C, Haas-Kogan DA, Kreissman SG, Khanna G, Rosen N, Park JR, La Quaglia MP.

J Clin Oncol. 2017 Jan 10;35(2):208-216. Epub 2016 Nov 21.


Comprehensive renal function evaluation in patients treated for synchronous bilateral Wilms tumor.

Interiano RB, McCarville MB, Santos ND, Mao S, Wu J, Dome JS, Kieran K, Williams MA, Brennan RC, Krasin MJ, Green DM, Davidoff AM.

J Pediatr Surg. 2017 Jan;52(1):98-103. doi: 10.1016/j.jpedsurg.2016.10.027. Epub 2016 Oct 27.


Long-term outcomes of pediatric and adolescent mediastinal germ cell tumors: a single pediatric oncology institutional experience.

Grabski DF, Pappo AS, Krasin MJ, Davidoff AM, Rao BN, Fernandez-Pineda I.

Pediatr Surg Int. 2017 Feb;33(2):235-244. doi: 10.1007/s00383-016-4020-0. Epub 2016 Nov 12.


Bortezomib sensitizes human glioblastoma cells to induction of apoptosis by type I interferons through NOXA expression and Mcl-1 cleavage.

Wang R, Davidoff AM, Pfeffer LM.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):128-134. doi: 10.1016/j.bbrc.2016.07.080. Epub 2016 Jul 20.


Pulmonary Function after Treatment for Childhood Cancer. A Report from the St. Jude Lifetime Cohort Study (SJLIFE).

Green DM, Zhu L, Wang M, Ness KK, Krasin MJ, Bhakta NH, McCarville MB, Srinivasan S, Stokes DC, Srivastava D, Ojha R, Shelton K, Pui CH, Armstrong GT, Mulrooney DA, Metzger M, Spunt SL, Navid F, Davidoff AM, Rao BN, Robison LL, Hudson MM.

Ann Am Thorac Soc. 2016 Sep;13(9):1575-85. doi: 10.1513/AnnalsATS.201601-022OC.


Limited Margin Radiation Therapy for Children and Young Adults With Ewing Sarcoma Achieves High Rates of Local Tumor Control.

Talleur AC, Navid F, Spunt SL, McCarville MB, Wu J, Mao S, Davidoff AM, Neel MD, Krasin MJ.

Int J Radiat Oncol Biol Phys. 2016 Sep 1;96(1):119-26. doi: 10.1016/j.ijrobp.2016.04.001. Epub 2016 Apr 12.


Long-term functional outcomes and quality of life in adult survivors of childhood extremity sarcomas: a report from the St. Jude Lifetime Cohort Study.

Fernandez-Pineda I, Hudson MM, Pappo AS, Bishop MW, Klosky JL, Brinkman TM, Srivastava DK, Neel MD, Rao BN, Davidoff AM, Krull KR, Mulrooney DA, Robison LL, Ness KK.

J Cancer Surviv. 2017 Feb;11(1):1-12. doi: 10.1007/s11764-016-0556-1. Epub 2016 Jun 4.


Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector.

Piras BA, Drury JE, Morton CL, Spence Y, Lockey TD, Nathwani AC, Davidoff AM, Meagher MM.

Mol Ther Methods Clin Dev. 2016 Mar 30;3:16015. doi: 10.1038/mtm.2016.15. eCollection 2016.


Feasibility of Pegylated Interferon in Children and Young Adults With Resected High-Risk Melanoma.

Navid F, Herzog CE, Sandoval J, Daryani VM, Stewart CF, Gattuso J, Mandrell B, Phipps S, Chemaitilly W, Sykes A, Davidoff AM, Shulkin BL, Bahrami A, Furman WL, Mao S, Wu J, Schiff D, Rao B, Pappo A.

Pediatr Blood Cancer. 2016 Jul;63(7):1207-13. doi: 10.1002/pbc.25983. Epub 2016 Apr 1.

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